-
1
-
-
0030777012
-
The capsaicin receptor: A heat-activated ion channel in the pain pathway
-
Caterina MJ, Schumacher MA, Tominaga M, Rosen TA, Levine JD, Julius D: The capsaicin receptor: A heat-activated ion channel in the pain pathway. Nature (1997) 389(6653):816-824.
-
(1997)
Nature
, vol.389
, Issue.6653
, pp. 816-824
-
-
Caterina, M.J.1
Schumacher, M.A.2
Tominaga, M.3
Rosen, T.A.4
Levine, J.D.5
Julius, D.6
-
2
-
-
0347504835
-
TRP channels as cellular sensors
-
Clapham DE: TRP channels as cellular sensors. Nature (2003) 426(6966):517-524.
-
(2003)
Nature
, vol.426
, Issue.6966
, pp. 517-524
-
-
Clapham, D.E.1
-
3
-
-
38449104252
-
Transient receptor potential (TRP) cation channels: Rewarding unique proteins
-
Nilius B: Transient receptor potential (TRP) cation channels: Rewarding unique proteins. Bull Mem Acad R Med Belg (2007) 162 (3-4) : 244-253.
-
(2007)
Bull. Mem Acad. R Med. Belg.
, vol.162
, Issue.3-4
, pp. 244-253
-
-
Nilius, B.1
-
4
-
-
0027988505
-
Protons: Small stimulants of capsaicinsensitive sensory nerves
-
Bevan S, Geppetti P: Protons: Small stimulants of capsaicinsensitive sensory nerves. Trends Neurosci (1994) 17(12):509-512.
-
(1994)
Trends Neurosci.
, vol.17
, Issue.12
, pp. 509-512
-
-
Bevan, S.1
Geppetti, P.2
-
5
-
-
0037062411
-
An endogenous capsaicin-like substance with high potency at recombinant and native vanilloid VR1 receptors
-
Huang SM, Bisogno T, Trevisani M, Al-Hayani A, De Petrocellis L, Fezza F, Tognetto M, Petros TJ, Krey JF, Chu CJ, Miller JD et al: An endogenous capsaicin-like substance with high potency at recombinant and native vanilloid VR1 receptors. Proc Natl Acad Sci USA (2002) 99(12):8400-8405.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, Issue.12
, pp. 8400-8405
-
-
Huang, S.M.1
Bisogno, T.2
Trevisani, M.3
Al-Hayani, A.4
De Petrocellis, L.5
Fezza, F.6
Tognetto, M.7
Petros, T.J.8
Krey, J.F.9
Chu, C.J.10
Miller, J.D.11
-
6
-
-
0004906771
-
Direct activation of capsaicin receptors by products of lipoxygenases: Endogenous capsaicin-like substances
-
Hwang SW, Cho H, Kwak J, Lee SY, Kang CJ, Jung J, Cho S, Min KH, Suh YG, Kim D, Oh U: Direct activation of capsaicin receptors by products of lipoxygenases: Endogenous capsaicin-like substances. Proc Natl Acad Sci USA (2000) 97(11):6155-6160.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, Issue.11
, pp. 6155-6160
-
-
Hwang, S.W.1
Cho, H.2
Kwak, J.3
Lee, S.Y.4
Kang, C.J.5
Jung, J.6
Cho, S.7
Min, K.H.8
Suh, Y.G.9
Kim, D.10
Oh, U.11
-
7
-
-
0032169804
-
The cloned capsaicin receptor integrates multiple pain-producing stimuli
-
Tominaga M, Caterina MJ, Malmberg AB, Rosen TA, Gilbert H, Skinner K, Raumann BE, Basbaum AI, Julius D: The cloned capsaicin receptor integrates multiple pain-producing stimuli. Neuron (1998) 21(3):531-543.
-
(1998)
Neuron
, vol.21
, Issue.3
, pp. 531-543
-
-
Tominaga, M.1
Caterina, M.J.2
Malmberg, A.B.3
Rosen, T.A.4
Gilbert, H.5
Skinner, K.6
Raumann, B.E.7
Basbaum, A.I.8
Julius, D.9
-
8
-
-
0027290987
-
Characterization of tachykinin receptors in ferret trachea by peptide agonists and nonpeptide antagonists
-
Geppetti P, Bertrand C, Bacci E, Huber O, Nadel JA: Characterization of tachykinin receptors in ferret trachea by peptide agonists and nonpeptide antagonists. Am J Physiol (1993) 265 (2 Pt 1) : L164-L169.
-
(1993)
Am. J. Physiol.
, vol.265
, Issue.1-2 PT.
-
-
Geppetti, P.1
Bertrand, C.2
Bacci, E.3
Huber, O.4
Nadel, J.A.5
-
9
-
-
0034744445
-
NK1 receptor stimulation causes contraction and inositol phosphate increase in medium-size human isolated bronchi
-
Amadesi S, Moreau J, Tognetto M, Springer J, Trevisani M, Naline E, Advenier C, Fisher A, Vinci D, Mapp C, Miotto D et al: NK1 receptor stimulation causes contraction and inositol phosphate increase in medium-size human isolated bronchi. Am J Respir Crit Care Med (2001) 163(5):1206-1211.
-
(2001)
Am. J. Respir Crit. Care Med.
, vol.163
, Issue.5
, pp. 1206-1211
-
-
Amadesi, S.1
Moreau, J.2
Tognetto, M.3
Springer, J.4
Trevisani, M.5
Naline, E.6
Advenier, C.7
Fisher, A.8
Vinci, D.9
Mapp, C.10
Miotto, D.11
-
10
-
-
0035381322
-
Tachykinin receptor antagonists: Potential in airways diseases
-
Joos GF, Pauwels RA: Tachykinin receptor antagonists: Potential in airways diseases. Curr Opin Pharmacol (2001) 1(3):235-241.
-
(2001)
Curr. Opin. Pharmacol.
, vol.1
, Issue.3
, pp. 235-241
-
-
Joos, G.F.1
Pauwels, R.A.2
-
11
-
-
0041695412
-
Hypotonicity induces TRPV4-mediated nociception in rat
-
Alessandri-Haber N, Yeh JJ, Boyd AE, Parada CA, Chen X, Reichling DB, Levine JD: Hypotonicity induces TRPV4-mediated nociception in rat. Neuron (2003) 39(3):497-511.
-
(2003)
Neuron
, vol.39
, Issue.3
, pp. 497-511
-
-
Alessandri-Haber, N.1
Yeh, J.J.2
Boyd, A.E.3
Parada, C.A.4
Chen, X.5
Reichling, D.B.6
Levine, J.D.7
-
12
-
-
34447542435
-
The menthol receptor TRPM8 is the principal detector of environmental cold
-
Bautista DM, Siemens J, Glazer JM, Tsuruda PR, Basbaum AI, Stucky CL, Jordt SE, Julius D: The menthol receptor TRPM8 is the principal detector of environmental cold. Nature (2007) 448(7150):204-208.
-
(2007)
Nature
, vol.448
, Issue.7150
, pp. 204-208
-
-
Bautista, D.M.1
Siemens, J.2
Glazer, J.M.3
Tsuruda, P.R.4
Basbaum, A.I.5
Stucky, C.L.6
Jordt, S.E.7
Julius, D.8
-
13
-
-
0033119629
-
A capsaicin-receptor homologue with a high threshold for noxious heat
-
Caterina MJ, Rosen TA, Tominaga M, Brake AJ, Julius D: A capsaicin-receptor homologue with a high threshold for noxious heat. Nature (1999) 398(6726):436-441.
-
(1999)
Nature
, vol.398
, Issue.6726
, pp. 436-441
-
-
Caterina, M.J.1
Rosen, T.A.2
Tominaga, M.3
Brake, A.J.4
Julius, D.5
-
14
-
-
0034721648
-
Vanilloid receptor-related osmotically activated channel (VR-OAC), a candidate vertebrate osmoreceptor
-
Liedtke W, Choe Y, Martí-Renom MA, Bell AM, Denis CS, Sali A, Hudspeth AJ, Friedman JM, Heller S: Vanilloid receptor-related osmotically activated channel (VR-OAC), a candidate vertebrate osmoreceptor. Cell (2000) 103(3):525-535.
-
(2000)
Cell.
, vol.103
, Issue.3
, pp. 525-535
-
-
Liedtke, W.1
Choe, Y.2
Martí-Renom, M.A.3
Bell, A.M.4
Denis, C.S.5
Sali, A.6
Hudspeth, A.J.7
Friedman, J.M.8
Heller, S.9
-
15
-
-
0037034931
-
Identification of a cold receptor reveals a general role for TRP channels in thermosensation
-
McKemy DD, Neuhausser WM, Julius D: Identification of a cold receptor reveals a general role for TRP channels in thermosensation. Nature (2002) 416(6876):52-58.
-
(2002)
Nature
, vol.416
, Issue.6876
, pp. 52-58
-
-
McKemy, D.D.1
Neuhausser, W.M.2
Julius, D.3
-
16
-
-
18344386202
-
A TRP channel that senses cold stimuli and menthol
-
Peier AM, Moqrich A, Hergarden AC, Reeve AJ, Andersson DA, Story GM, Earley TJ, Dragoni I, McIntyre P, Bevan S, Patapoutian A: A TRP channel that senses cold stimuli and menthol. Cell (2002) 108(5):705-715.
-
(2002)
Cell.
, vol.108
, Issue.5
, pp. 705-715
-
-
Peier, A.M.1
Moqrich, A.2
Hergarden, A.C.3
Reeve, A.J.4
Andersson, D.A.5
Story, G.M.6
Earley, T.J.7
Dragoni, I.8
McIntyre, P.9
Bevan, S.10
Patapoutian, A.11
-
17
-
-
76949094139
-
TRPV2 has a pivotal role in macrophage particle binding and phagocytosis
-
Link TM, Park U, Vonakis BM, Raben DM, Soloski MJ, Caterina MJ: TRPV2 has a pivotal role in macrophage particle binding and phagocytosis. Nat Immunol (2010) 11(3):232-239.
-
(2010)
Nat. Immunol.
, vol.11
, Issue.3
, pp. 232-239
-
-
Link, T.M.1
Park, U.2
Vonakis, B.M.3
Raben, D.M.4
Soloski, M.J.5
Caterina, M.J.6
-
18
-
-
17644426325
-
Nociceptor and hair cell transducer properties of TRPA1, a channel for pain and hearing
-
Nagata K, Duggan A, Kumar G, García-Añoveros J: Nociceptor and hair cell transducer properties of TRPA1, a channel for pain and hearing. J Neurosci (2005) 25(16):4052-4061.
-
(2005)
J. Neurosci.
, vol.25
, Issue.16
, pp. 4052-4061
-
-
Nagata, K.1
Duggan, A.2
Kumar, G.3
García-Añoveros, J.4
-
19
-
-
0345616438
-
ANKTM1, a TRP-like channel expressed in nociceptive neurons, is activated by cold temperatures
-
Story GM, Peier AM, Reeve AJ, Eid SR, Mosbacher J, Hricik TR, Earley TJ, Hergarden AC, Andersson DA, Hwang SW, McIntyre P et al: ANKTM1, a TRP-like channel expressed in nociceptive neurons, is activated by cold temperatures. Cell (2003) 112(6):819-829.
-
(2003)
Cell.
, vol.112
, Issue.6
, pp. 819-829
-
-
Story, G.M.1
Peier, A.M.2
Reeve, A.J.3
Eid, S.R.4
Mosbacher, J.5
Hricik, T.R.6
Earley, T.J.7
Hergarden, A.C.8
Andersson, D.A.9
Hwang, S.W.10
McIntyre, P.11
-
20
-
-
1842475312
-
Noxious cold ion channel TRPA1 is activated by pungent compounds and bradykinin
-
Bandell M, Story GM, Hwang SW, Viswanath V, Eid SR, Petrus MJ, Earley TJ, Patapoutian A: Noxious cold ion channel TRPA1 is activated by pungent compounds and bradykinin. Neuron (2004) 41(6):849-857.
-
(2004)
Neuron
, vol.41
, Issue.6
, pp. 849-857
-
-
Bandell, M.1
Story, G.M.2
Hwang, S.W.3
Viswanath, V.4
Eid, S.R.5
Petrus, M.J.6
Earley, T.J.7
Patapoutian, A.8
-
21
-
-
33845900989
-
TRP channel activation by reversible covalent modification
-
Hinman A, Chuang HH, Bautista DM, Julius D: TRP channel activation by reversible covalent modification. Proc Natl Acad Sci USA (2006) 103(51):19564-19568.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, Issue.51
, pp. 19564-19568
-
-
Hinman, A.1
Chuang, H.H.2
Bautista, D.M.3
Julius, D.4
-
22
-
-
1642430679
-
Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1
-
Jordt SE, Bautista DM, Chuang HH, McKemy DD, Zygmunt PM, Högestätt ED, Meng ID, Julius D: Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1. Nature (2004) 427(6971):260-265.
-
(2004)
Nature
, vol.427
, Issue.6971
, pp. 260-265
-
-
Jordt, S.E.1
Bautista, D.M.2
Chuang, H.H.3
McKemy, D.D.4
Zygmunt, P.M.5
Högestätt, E.D.6
Meng, I.D.7
Julius, D.8
-
23
-
-
67049119907
-
A sensory neuronal ion channel essential for airway inflammation and hyperreactivity in asthma
-
•• TRPA1-null mice demonstrated markedly reduced bronchial hyper-responsiveness and pro-asthmatic lung cytokine levels in a model of airway allergic response, as compared with wild-type littermates
-
Caceres AI, Brackmann M, Elia MD, Bessac BF, del Camino D, D'Amours M, Witek JS, Fanger CM, Chong JA, Hayward NJ, Homer RJ et al: A sensory neuronal ion channel essential for airway inflammation and hyperreactivity in asthma. Proc Natl Acad Sci USA (2009) 106(22):9099-9104. •• TRPA1-null mice demonstrated markedly reduced bronchial hyper-responsiveness and pro-asthmatic lung cytokine levels in a model of airway allergic response, as compared with wild-type littermates.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, Issue.22
, pp. 9099-9104
-
-
Caceres, A.I.1
Brackmann, M.2
Elia, M.D.3
Bessac, B.F.4
Camino, D.D.5
D'Amours, M.6
Witek, J.S.7
Fanger, C.M.8
Chong, J.A.9
Hayward, N.J.10
Homer, R.J.11
-
24
-
-
46749091281
-
Cigarette smoke-induced neurogenic inflammation is mediated by α, β-unsaturated aldehydes and the TRPA1 receptor in rodents
-
•• Acrolein and crotonaldehyde, both of which are present in cigarette smoke, mediated the airway early inflammatory response to cigarette smoke inhalation via TRPA1 activation
-
Andrè E, Campi B, Materazzi S, Trevisani M, Amadesi S, Massi D, Creminon C, Vaksman N, Nassini R, Civelli M, Baraldi PG et al: Cigarette smoke-induced neurogenic inflammation is mediated by α, β-unsaturated aldehydes and the TRPA1 receptor in rodents. J Clin Invest (2008) 118(7):2574-2582. •• Acrolein and crotonaldehyde, both of which are present in cigarette smoke, mediated the airway early inflammatory response to cigarette smoke inhalation via TRPA1 activation.
-
(2008)
J. Clin. Invest.
, vol.118
, Issue.7
, pp. 2574-2582
-
-
Andrè, E.1
Campi, B.2
Materazzi, S.3
Trevisani, M.4
Amadesi, S.5
Massi, D.6
Creminon, C.7
Vaksman, N.8
Nassini, R.9
Civelli, M.10
Baraldi, P.G.11
-
25
-
-
33746471163
-
Immunohistochemical co-localization of transient receptor potential vanilloid (TRPV) 1 and sensory neuropeptides in the guinea-pig respiratory system
-
Watanabe N, Horie S, Michael GJ, Keir S, Spina D, Page CP, Priestley JV: Immunohistochemical co-localization of transient receptor potential vanilloid (TRPV) 1 and sensory neuropeptides in the guinea-pig respiratory system. Neuroscience (2006) 141(3):1533-1543.
-
(2006)
Neuroscience
, vol.141
, Issue.3
, pp. 1533-1543
-
-
Watanabe, N.1
Horie, S.2
Michael, G.J.3
Keir, S.4
Spina, D.5
Page, C.P.6
Priestley, J.V.7
-
26
-
-
0021869371
-
Bronchoconstrictor response to inhaled capsaicin in humans
-
Fuller RW, Dixon CM, Barnes PJ: Bronchoconstrictor response to inhaled capsaicin in humans. J Appl Physiol (1985) 58(4):1080-1084.
-
(1985)
J. Appl. Physiol.
, vol.58
, Issue.4
, pp. 1080-1084
-
-
Fuller, R.W.1
Dixon, C.M.2
Barnes, P.J.3
-
27
-
-
0020606221
-
Substance P and capsaicin-induced contraction of human bronchi
-
Lundberg JM, Martling CR, Saria A: Substance P and capsaicin-induced contraction of human bronchi. Acta Physiol Scand (1983) 119(1):49-53.
-
(1983)
Acta Physiol. Scand.
, vol.119
, Issue.1
, pp. 49-53
-
-
Lundberg, J.M.1
Martling, C.R.2
Saria, A.3
-
28
-
-
33847659728
-
Effect of an NK1/NK2 receptor antagonist on airway responses and inflammation to allergen in asthma
-
Boot JD, de Haas S, Tarasevych S, Roy C, Wang L, Amin D, Cohen J, Sterk PJ, Miller B, Paccaly A, Burggraaf J et al: Effect of an NK1/NK2 receptor antagonist on airway responses and inflammation to allergen in asthma. Am J Respir Crit Care Med (2007) 175(5):450-457.
-
(2007)
Am. J. Respir Crit. Care Med.
, vol.175
, Issue.5
, pp. 450-457
-
-
Boot, J.D.1
De Haas, S.2
Tarasevych, S.3
Roy, C.4
Wang, L.5
Amin, D.6
Cohen, J.7
Sterk, P.J.8
Miller, B.9
Paccaly, A.10
Burggraaf, J.11
-
29
-
-
0028990953
-
Effect of an NK1 receptor antagonist (CP-99, 994) on hypertonic saline-induced bronchoconstriction and cough in male asthmatic subjects
-
Fahy JV, Wong HH, Geppetti P, Reis JM, Harris SC, Maclean DB, Nadel JA, Boushey HA: Effect of an NK1 receptor antagonist (CP-99, 994) on hypertonic saline-induced bronchoconstriction and cough in male asthmatic subjects. Am J Respir Crit Care Med (1995) 152(3):879-884.
-
(1995)
Am. J. Respir Crit. Care Med.
, vol.152
, Issue.3
, pp. 879-884
-
-
Fahy, J.V.1
Wong, H.H.2
Geppetti, P.3
Reis, J.M.4
Harris, S.C.5
Maclean, D.B.6
Nadel, J.A.7
Boushey, H.A.8
-
30
-
-
0021344458
-
Capsaicin inhalation in man and the effects of sodium cromoglycate
-
Collier JG, Fuller RW: Capsaicin inhalation in man and the effects of sodium cromoglycate. Br J Pharmacol (1984) 81(1):113-117.
-
(1984)
Br. J. Pharmacol.
, vol.81
, Issue.1
, pp. 113-117
-
-
Collier, J.G.1
Fuller, R.W.2
-
31
-
-
0036308546
-
Chronic cough and the cough refex in common lung diseases
-
Higenbottam T: Chronic cough and the cough refex in common lung diseases. Pulm Pharmacol Ther (2002) 15(3):241-247.
-
(2002)
Pulm Pharmacol. Ther.
, vol.15
, Issue.3
, pp. 241-247
-
-
Higenbottam, T.1
-
32
-
-
0027324236
-
Effects of aerosol-applied capsaicin, histamine and prostaglandin E2 on airway sensory receptors of anaesthetized cats
-
Mohammed SP, Higenbottam TW, Adcock JJ: Effects of aerosol-applied capsaicin, histamine and prostaglandin E2 on airway sensory receptors of anaesthetized cats. J Physiol (1993) 469:51-66.
-
(1993)
J. Physiol.
, vol.469
, pp. 51-66
-
-
Mohammed, S.P.1
Higenbottam, T.W.2
Adcock, J.J.3
-
33
-
-
33745817390
-
Sensory transduction in coughassociated nerves
-
Kollarik M, Undem BJ: Sensory transduction in coughassociated nerves. Respir Physiol Neurobiol (2006) 152(3):243-254.
-
(2006)
Respir Physiol. Neurobiol.
, vol.152
, Issue.3
, pp. 243-254
-
-
Kollarik, M.1
Undem, B.J.2
-
34
-
-
29244463541
-
Synergistic interactions between airway afferent nerve subtypes regulating the cough refex in guinea-pigs
-
Mazzone SB, Mori N, Canning BJ: Synergistic interactions between airway afferent nerve subtypes regulating the cough refex in guinea-pigs. J Physiol (2005) 569 (Pt 2) : 559-573.
-
(2005)
J. Physiol.
, vol.569
, Issue.2 PT.
, pp. 559-573
-
-
Mazzone, S.B.1
Mori, N.2
Canning, B.J.3
-
35
-
-
2442713905
-
Ethanol causes inflammation in the airways by a neurogenic and TRPV1-dependent mechanism
-
Trevisani M, Gazzieri D, Benvenuti F, Campi B, Dinh QT, Groneberg DA, Rigoni M, Emonds-Alt X, Creminon C, Fischer A, Geppetti P et al: Ethanol causes inflammation in the airways by a neurogenic and TRPV1-dependent mechanism. J Pharmacol Exp Ther (2004) 309(3):1167-1173.
-
(2004)
J. Pharmacol. Exp. Ther.
, vol.309
, Issue.3
, pp. 1167-1173
-
-
Trevisani, M.1
Gazzieri, D.2
Benvenuti, F.3
Campi, B.4
Dinh, Q.T.5
Groneberg, D.A.6
Rigoni, M.7
Emonds-Alt, X.8
Creminon, C.9
Fischer, A.10
Geppetti, P.11
-
36
-
-
0028805448
-
Capsazepine inhibits cough induced by capsaicin and citric acid but not by hypertonic saline in guinea pigs
-
Lalloo UG, Fox AJ, Belvisi MG, Chung KF, Barnes PJ: Capsazepine inhibits cough induced by capsaicin and citric acid but not by hypertonic saline in guinea pigs. J Appl Physiol (1995) 79(4):1082-1087.
-
(1995)
J. Appl. Physiol.
, vol.79
, Issue.4
, pp. 1082-1087
-
-
Lalloo, U.G.1
Fox, A.J.2
Belvisi, M.G.3
Chung, K.F.4
Barnes, P.J.5
-
37
-
-
4544227074
-
Antitussive activity of iodoresiniferatoxin in guinea pigs
-
Trevisani M, Milan A, Gatti R, Zanasi A, Harrison S, Fontana G, Morice AH, Geppetti P: Antitussive activity of iodoresiniferatoxin in guinea pigs. Thorax (2004) 59(9):769-772.
-
(2004)
Thorax
, vol.59
, Issue.9
, pp. 769-772
-
-
Trevisani, M.1
Milan, A.2
Gatti, R.3
Zanasi, A.4
Harrison, S.5
Fontana, G.6
Morice, A.H.7
Geppetti, P.8
-
38
-
-
0036714577
-
Mechanisms of acid-induced activation of airway afferent nerve fibres in guinea-pig
-
Kollarik M, Undem BJ: Mechanisms of acid-induced activation of airway afferent nerve fibres in guinea-pig. J Physiol (2002) 543 (Pt 2) : 591-600.
-
(2002)
J. Physiol.
, vol.543
, Issue.2 PT.
, pp. 591-600
-
-
Kollarik, M.1
Undem, B.J.2
-
39
-
-
0027999369
-
Effect of inhaled menthol on citric acid induced cough in normal subjects
-
Morice AH, Marshall AE, Higgins KS, Grattan TJ: Effect of inhaled menthol on citric acid induced cough in normal subjects. Thorax (1994) 49(10):1024-1026.
-
(1994)
Thorax
, vol.49
, Issue.10
, pp. 1024-1026
-
-
Morice, A.H.1
Marshall, A.E.2
Higgins, K.S.3
Grattan, T.J.4
-
40
-
-
70449534119
-
TRPA1 agonists evoke coughing in guinea pig and human volunteers
-
Birrell MA, Belvisi MG, Grace M, Sadofsky L, Faruqi S, Hele DJ, Maher SA, Freund-Michel V, Morice AH: TRPA1 agonists evoke coughing in guinea pig and human volunteers. Am J Respir Crit Care Med (2009) 180(11):1042-1047.
-
(2009)
Am. J. Respir Crit. Care Med.
, vol.180
, Issue.11
, pp. 1042-1047
-
-
Birrell, M.A.1
Belvisi, M.G.2
Grace, M.3
Sadofsky, L.4
Faruqi, S.5
Hele, D.J.6
Maher, S.A.7
Freund-Michel, V.8
Morice, A.H.9
-
41
-
-
70350543343
-
Transient receptor potential ankyrin receptor 1 is a novel target for pro-tussive agents
-
Andrè E, Gatti R, Trevisani M, Preti D, Baraldi PG, Patacchini R, Geppetti P: Transient receptor potential ankyrin receptor 1 is a novel target for pro-tussive agents. Br J Pharmacol (2009) 158(6):1621-1628.
-
(2009)
Br. J. Pharmacol.
, vol.158
, Issue.6
, pp. 1621-1628
-
-
Andrè, E.1
Gatti, R.2
Trevisani, M.3
Preti, D.4
Baraldi, P.G.5
Patacchini, R.6
Geppetti, P.7
-
42
-
-
0033548702
-
An ankyrin-like protein with transmembrane domains is specifically lost after oncogenic transformation of human fibroblasts
-
Jaquemar D, Schenker T, Trueb B: An ankyrin-like protein with transmembrane domains is specifically lost after oncogenic transformation of human fibroblasts. J Biol Chem (1999) 274(11):7325-7333.
-
(1999)
J. Biol. Chem.
, vol.274
, Issue.11
, pp. 7325-7333
-
-
Jaquemar, D.1
Schenker, T.2
Trueb, B.3
-
43
-
-
0141783754
-
Vanilloid receptor activation by 2-and 10-μm particles induces responses leading to apoptosis in human airway epithelial cells
-
Agopyan N, Bhatti T, Yu S, Simon SA: Vanilloid receptor activation by 2-and 10-μm particles induces responses leading to apoptosis in human airway epithelial cells. Toxicol Appl Pharmacol (2003) 192(1):21-35.
-
(2003)
Toxicol Appl. Pharmacol.
, vol.192
, Issue.1
, pp. 21-35
-
-
Agopyan, N.1
Bhatti, T.2
Yu, S.3
Simon, S.A.4
-
44
-
-
0035927651
-
2-mediated inhibition
-
2-mediated inhibition. Nature (2001) 411(6840):957-962.
-
(2001)
Nature
, vol.411
, Issue.6840
, pp. 957-962
-
-
Chuang, H.H.1
Prescott, E.D.2
Kong, H.3
Shields, S.4
Jordt, S.E.5
Basbaum, A.I.6
Chao, M.V.7
Julius, D.8
-
45
-
-
0034700494
-
Induction of vanilloid receptor channel activity by protein kinase C
-
Premkumar LS, Ahern GP: Induction of vanilloid receptor channel activity by protein kinase C. Nature (2000) 408(6815):985-990.
-
(2000)
Nature
, vol.408
, Issue.6815
, pp. 985-990
-
-
Premkumar, L.S.1
Ahern, G.P.2
-
46
-
-
2342604388
-
Protease-activated receptor 2 sensitizes the capsaicin receptor transient receptor potential vanilloid receptor 1 to induce hyperalgesia
-
Amadesi S, Nie J, Vergnolle N, Cottrell GS, Grady EF, Trevisani M, Manni C, Geppetti P, McRoberts JA, Ennes H, Davis JB et al: Protease-activated receptor 2 sensitizes the capsaicin receptor transient receptor potential vanilloid receptor 1 to induce hyperalgesia. J Neurosci (2004) 24(18):4300-4312.
-
(2004)
J. Neurosci.
, vol.24
, Issue.18
, pp. 4300-4312
-
-
Amadesi, S.1
Nie, J.2
Vergnolle, N.3
Cottrell, G.S.4
Grady, E.F.5
Trevisani, M.6
Manni, C.7
Geppetti, P.8
McRoberts, J.A.9
Ennes, H.10
Davis, J.B.11
-
47
-
-
2442468123
-
Proteinase-activated receptor 2-mediated potentiation of transient receptor potential vanilloid subfamily 1 activity reveals a mechanism for proteinase-induced inflammatory pain
-
Dai Y, Moriyama T, Higashi T, Togashi K, Kobayashi K, Yamanaka H, Tominaga M, Noguchi K: Proteinase-activated receptor 2-mediated potentiation of transient receptor potential vanilloid subfamily 1 activity reveals a mechanism for proteinase-induced inflammatory pain. J Neurosci (2004) 24(18):4293-4299.
-
(2004)
J. Neurosci.
, vol.24
, Issue.18
, pp. 4293-4299
-
-
Dai, Y.1
Moriyama, T.2
Higashi, T.3
Togashi, K.4
Kobayashi, K.5
Yamanaka, H.6
Tominaga, M.7
Noguchi, K.8
-
48
-
-
0034977496
-
The vanilloid receptor (VR1)-mediated effects of anandamide are potently enhanced by the cAMP-dependent protein kinase
-
De Petrocellis L, Harrison S, Bisogno T, Tognetto M, Brandi I, Smith GD, Creminon C, Davis JB, Geppetti P, Di Marzo V: The vanilloid receptor (VR1)-mediated effects of anandamide are potently enhanced by the cAMP-dependent protein kinase. J Neurochem (2001) 77(6):1660-1663.
-
(2001)
J. Neurochem.
, vol.77
, Issue.6
, pp. 1660-1663
-
-
De Petrocellis, L.1
Harrison, S.2
Bisogno, T.3
Tognetto, M.4
Brandi, I.5
Smith, G.D.6
Creminon, C.7
Davis, J.B.8
Geppetti, P.9
Marzo, V.D.10
-
49
-
-
85047696992
-
Ethanol elicits and potentiates nociceptor responses via the vanilloid receptor-1
-
Trevisani M, Smart D, Gunthorpe MJ, Tognetto M, Barbieri M, Campi B, Amadesi S, Gray J, Jerman JC, Brough SJ, Owen D et al: Ethanol elicits and potentiates nociceptor responses via the vanilloid receptor-1. Nat Neurosci (2002) 5(6):546-551.
-
(2002)
Nat. Neurosci.
, vol.5
, Issue.6
, pp. 546-551
-
-
Trevisani, M.1
Smart, D.2
Gunthorpe, M.J.3
Tognetto, M.4
Barbieri, M.5
Campi, B.6
Amadesi, S.7
Gray, J.8
Jerman, J.C.9
Brough, S.J.10
Owen, D.11
-
50
-
-
58349089496
-
Ethanol potentiates the TRPV1-mediated cough in the guinea pig
-
• Reports that several of the effects produced or potentiated by ethanol in the respiratory system are mediated by TRPV1 stimulation
-
Gatti R, Andre E, Barbara C, Dinh TQ, Fontana G, Fischer A, Geppetti P, Trevisani M: Ethanol potentiates the TRPV1-mediated cough in the guinea pig. Pulm Pharmacol Ther (2009) 22(1):33-36. • Reports that several of the effects produced or potentiated by ethanol in the respiratory system are mediated by TRPV1 stimulation.
-
(2009)
Pulm Pharmacol. Ther.
, vol.22
, Issue.1
, pp. 33-36
-
-
Gatti, R.1
Andre, E.2
Barbara, C.3
Dinh, T.Q.4
Fontana, G.5
Fischer, A.6
Geppetti, P.7
Trevisani, M.8
-
52
-
-
50849092862
-
Inhaled ethanol potentiates the cough response to capsaicin in patients with airway sensory hyperreactivity
-
Millqvist E, Ternesten-Hasséus E, Bende M: Inhaled ethanol potentiates the cough response to capsaicin in patients with airway sensory hyperreactivity. Pulm Pharmacol Ther (2008) 21(5):794-797.
-
(2008)
Pulm Pharmacol. Ther.
, vol.21
, Issue.5
, pp. 794-797
-
-
Millqvist, E.1
Ternesten-Hasséus, E.2
Bende, M.3
-
53
-
-
34548834173
-
Sulfur-dioxide exposure increases TRPV1-mediated responses in nodose ganglia cells and augments cough in guinea pigs
-
McLeod RL, Jia Y, McHugh NA, Fernandez X, Mingo GG, Wang X, Parra LE, Chen J, Brown D, Bolser DC, Kreutner W et al: Sulfur-dioxide exposure increases TRPV1-mediated responses in nodose ganglia cells and augments cough in guinea pigs. Pulm Pharmacol Ther (2007) 20(6):750-757.
-
(2007)
Pulm Pharmacol. Ther.
, vol.20
, Issue.6
, pp. 750-757
-
-
McLeod, R.L.1
Jia, Y.2
McHugh, N.A.3
Fernandez, X.4
Mingo, G.G.5
Wang, X.6
Parra, L.E.7
Chen, J.8
Brown, D.9
Bolser, D.C.10
Kreutner, W.11
-
54
-
-
21744443081
-
Hydrogen sulfde is a novel mediator of lipopolysaccharideinduced inflammation in the mouse
-
Li L, Bhatia M, Zhu YZ, Zhu YC, Ramnath RD, Wang ZJ, Anuar FB, Whiteman M, Salto-Tellez M, Moore PK: Hydrogen sulfde is a novel mediator of lipopolysaccharideinduced inflammation in the mouse. FASEB J (2005) 19(9):1196-1198.
-
(2005)
FASEB J.
, vol.19
, Issue.9
, pp. 1196-1198
-
-
Li, L.1
Bhatia, M.2
Zhu, Y.Z.3
Zhu, Y.C.4
Ramnath, R.D.5
Wang, Z.J.6
Anuar, F.B.7
Whiteman, M.8
Salto-Tellez, M.9
Moore, P.K.10
-
55
-
-
30544435419
-
Hydrogen sulfde causes vanilloid receptor 1-mediated neurogenic inflammation in the airways
-
Trevisani M, Patacchini R, Nicoletti P, Gatti R, Gazzieri D, Lissi N, Zagli G, Creminon C, Geppetti P, Harrison S: Hydrogen sulfde causes vanilloid receptor 1-mediated neurogenic inflammation in the airways. Br J Pharmacol (2005) 145(8):1123-1131.
-
(2005)
Br. J. Pharmacol.
, vol.145
, Issue.8
, pp. 1123-1131
-
-
Trevisani, M.1
Patacchini, R.2
Nicoletti, P.3
Gatti, R.4
Gazzieri, D.5
Lissi, N.6
Zagli, G.7
Creminon, C.8
Geppetti, P.9
Harrison, S.10
-
56
-
-
13644262070
-
Capsazepine, a vanilloid antagonist, abolishes tonic responses induced by 20-HETE on guinea pig airway smooth muscle
-
Rousseau E, Cloutier M, Morin C, Proteau S: Capsazepine, a vanilloid antagonist, abolishes tonic responses induced by 20-HETE on guinea pig airway smooth muscle. Am J Physiol Lung Cell Mol Physiol (2005) 288 (3) : L460-L470.
-
(2005)
Am. J. Physiol. Lung Cell. Mol. Physiol.
, vol.288
, Issue.3
-
-
Rousseau, E.1
Cloutier, M.2
Morin, C.3
Proteau, S.4
-
57
-
-
9644269845
-
Increased expression of transient receptor potential vanilloid-1 in airway nerves of chronic cough
-
Groneberg DA, Niimi A, Dinh QT, Cosio B, Hew M, Fischer A, Chung KF: Increased expression of transient receptor potential vanilloid-1 in airway nerves of chronic cough. Am J Respir Crit Care Med (2004) 170(12):1276-1280.
-
(2004)
Am. J. Respir Crit. Care Med.
, vol.170
, Issue.12
, pp. 1276-1280
-
-
Groneberg, D.A.1
Niimi, A.2
Dinh, Q.T.3
Cosio, B.4
Hew, M.5
Fischer, A.6
Chung, K.F.7
-
58
-
-
33646045075
-
TRPA1 mediates the inflammatory actions of environmental irritants and proalgesic agents
-
•• Reports that acrolein, an environmental pollutant and oxidative stress byproduct, is a TRPA1 stimulant
-
Bautista DM, Jordt SE, Nikai T, Tsuruda PR, Read AJ, Poblete J, Yamoah EN, Basbaum AI, Julius D: TRPA1 mediates the inflammatory actions of environmental irritants and proalgesic agents. Cell (2006) 124(6):1269-1282. •• Reports that acrolein, an environmental pollutant and oxidative stress byproduct, is a TRPA1 stimulant.
-
(2006)
Cell.
, vol.124
, Issue.6
, pp. 1269-1282
-
-
Bautista, D.M.1
Jordt, S.E.2
Nikai, T.3
Tsuruda, P.R.4
Read, A.J.5
Poblete, J.6
Yamoah, E.N.7
Basbaum, A.I.8
Julius, D.9
-
59
-
-
34548094044
-
4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1
-
•• Reports that HNE, a major peroxidation byproduct of plasma membrane phospholipids, is a signaling molecule that causes pain and inflammation via TRPA1 activation
-
Trevisani M, Siemens J, Materazzi S, Bautista DM, Nassini R, Campi B, Imamachi N, Andrè E, Patacchini R, Cottrell GS, Gatti R et al: 4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1. Proc Natl Acad Sci USA (2007) 104(33):13519-13524. •• Reports that HNE, a major peroxidation byproduct of plasma membrane phospholipids, is a signaling molecule that causes pain and inflammation via TRPA1 activation.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, Issue.33
, pp. 13519-13524
-
-
Trevisani, M.1
Siemens, J.2
Materazzi, S.3
Bautista, D.M.4
Nassini, R.5
Campi, B.6
Imamachi, N.7
Andrè, E.8
Patacchini, R.9
Cottrell, G.S.10
Gatti, R.11
-
60
-
-
50149097238
-
COX-dependent fatty acid metabolites cause pain through activation of the irritant receptor TRPA1
-
•• Reports that COX-dependent ie, cyclopentenone prostaglandins or-independent ie, cyclopentenone isoprostane electrophillic arachidonic acid metabolites are TRPA1 agonists
-
Materazzi S, Nassini R, Andrè E, Campi B, Amadesi S, Trevisani M, Bunnett NW, Patacchini R, Geppetti P: COX-dependent fatty acid metabolites cause pain through activation of the irritant receptor TRPA1. Proc Natl Acad Sci USA (2008) 105(33):12045-12050. •• Reports that COX-dependent (ie, cyclopentenone prostaglandins) or-independent (ie, cyclopentenone isoprostane) electrophillic arachidonic acid metabolites are TRPA1 agonists.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, Issue.33
, pp. 12045-12050
-
-
Materazzi, S.1
Nassini, R.2
Andrè, E.3
Campi, B.4
Amadesi, S.5
Trevisani, M.6
Bunnett, N.W.7
Patacchini, R.8
Geppetti, P.9
-
61
-
-
34447121851
-
Sensitization of TRPA1 by PAR2 contributes to the sensation of inflammatory pain
-
Dai Y, Wang S, Tominaga M, Yamamoto S, Fukuoka T, Higashi T, Kobayashi K, Obata K, Yamanaka H, Noguchi K: Sensitization of TRPA1 by PAR2 contributes to the sensation of inflammatory pain. J Clin Invest (2007) 117(7):1979-1987.
-
(2007)
J. Clin. Invest.
, vol.117
, Issue.7
, pp. 1979-1987
-
-
Dai, Y.1
Wang, S.2
Tominaga, M.3
Yamamoto, S.4
Fukuoka, T.5
Higashi, T.6
Kobayashi, K.7
Obata, K.8
Yamanaka, H.9
Noguchi, K.10
-
62
-
-
44949182742
-
Phospholipase C and protein kinase A mediate bradykinin sensitization of TRPA1: A molecular mechanism of inflammatory pain
-
Wang S, Dai Y, Fukuoka T, Yamanaka H, Kobayashi K, Obata K, Cui X, Tominaga M, Noguchi K: Phospholipase C and protein kinase A mediate bradykinin sensitization of TRPA1: A molecular mechanism of inflammatory pain. Brain (2008) 131 (Pt 5) : 1241-1251.
-
(2008)
Brain
, vol.131
, Issue.5 PT.
, pp. 1241-1251
-
-
Wang, S.1
Dai, Y.2
Fukuoka, T.3
Yamanaka, H.4
Kobayashi, K.5
Obata, K.6
Cui, X.7
Tominaga, M.8
Noguchi, K.9
-
63
-
-
0037102347
-
4-Hydroxy-2-nonenal, a specific lipid peroxidation product, is elevated in lungs of patients with chronic obstructive pulmonary disease
-
Rahman I, van Schadewijk AA, Crowther AJ, Hiemstra PS, Stolk J, MacNee W, De Boer WI: 4-Hydroxy-2-nonenal, a specific lipid peroxidation product, is elevated in lungs of patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2002) 166(4):490-495.
-
(2002)
Am. J. Respir Crit. Care Med.
, vol.166
, Issue.4
, pp. 490-495
-
-
Rahman, I.1
Van Schadewijk, A.A.2
Crowther, A.J.3
Hiemstra, P.S.4
Stolk, J.5
MacNee, W.6
De Boer, W.I.7
-
64
-
-
33644806753
-
The transient receptor potential vanilloid 1: Role in airway inflammation and disease
-
Geppetti P, Materazzi S, Nicoletti P: The transient receptor potential vanilloid 1: Role in airway inflammation and disease. Eur J Pharmacol (2006) 533 (1-3) : 207-214.
-
(2006)
Eur. J. Pharmacol.
, vol.533
, Issue.1-3
, pp. 207-214
-
-
Geppetti, P.1
Materazzi, S.2
Nicoletti, P.3
-
65
-
-
0033910751
-
Capsaicin responsiveness and cough in asthma and chronic obstructive pulmonary disease
-
Doherty MJ, Mister R, Pearson MG, Calverley PM: Capsaicin responsiveness and cough in asthma and chronic obstructive pulmonary disease. Thorax (2000) 55(8):643-649.
-
(2000)
Thorax
, vol.55
, Issue.8
, pp. 643-649
-
-
Doherty, M.J.1
Mister, R.2
Pearson, M.G.3
Calverley, P.M.4
-
66
-
-
0028595979
-
Cough receptor sensitivity and bronchial responsiveness in patients with only chronic nonproductive cough: In view of effect of bronchodilator therapy
-
Fujimura M, Kamio Y, Hashimoto T, Matsuda T: Cough receptor sensitivity and bronchial responsiveness in patients with only chronic nonproductive cough: In view of effect of bronchodilator therapy. J Asthma (1994) 31(6):463-472.
-
(1994)
J. Asthma
, vol.31
, Issue.6
, pp. 463-472
-
-
Fujimura, M.1
Kamio, Y.2
Hashimoto, T.3
Matsuda, T.4
-
67
-
-
0028352672
-
The effect of anticholinergic bronchodilator therapy on cough during upper respiratory tract infections
-
Lowry R, Wood A, Higenbottam T: The effect of anticholinergic bronchodilator therapy on cough during upper respiratory tract infections. Br J Clin Pharmacol (1994) 37(2):187-191.
-
(1994)
Br. J. Clin. Pharmacol.
, vol.37
, Issue.2
, pp. 187-191
-
-
Lowry, R.1
Wood, A.2
Higenbottam, T.3
-
68
-
-
0023200791
-
Angiotensinconverting enzyme and the cough refex
-
Morice AH, Lowry R, Brown MJ, Higenbottam T: Angiotensinconverting enzyme and the cough refex. Lancetv (1987) 2(8568):1116-1118.
-
(1987)
Lancetv
, vol.2
, Issue.8568
, pp. 1116-1118
-
-
Morice, A.H.1
Lowry, R.2
Brown, M.J.3
Higenbottam, T.4
-
69
-
-
0028142225
-
Capsaicin cough sensitivity decreases with successful treatment of chronic cough
-
O'Connell F, Thomas VE, Pride NB, Fuller RW: Capsaicin cough sensitivity decreases with successful treatment of chronic cough. Am J Respir Crit Care Med (1994) 150(2):374-380.
-
(1994)
Am. J. Respir Crit. Care Med.
, vol.150
, Issue.2
, pp. 374-380
-
-
O'Connell, F.1
Thomas, V.E.2
Pride, N.B.3
Fuller, R.W.4
-
70
-
-
0032970173
-
Vanilloid (capsaicin) receptors and mechanisms
-
Szallasi A, Blumberg PM: Vanilloid (capsaicin) receptors and mechanisms. Pharmacol Rev (1999) 51(2):159-212.
-
(1999)
Pharmacol. Rev.
, vol.51
, Issue.2
, pp. 159-212
-
-
Szallasi, A.1
Blumberg, P.M.2
-
71
-
-
0023070412
-
Capsaicin and nociception
-
Szolcsányi J: Capsaicin and nociception. Acta Physiol Hung (1987) 69 (3-4) : 323-332.
-
(1987)
Acta Physiol. Hung
, vol.69
, Issue.3-4
, pp. 323-332
-
-
Szolcsányi, J.1
-
73
-
-
33744993480
-
Expression and localization of TRPV1 in human nasal mucosa
-
Seki N, Shirasaki H, Kikuchi M, Sakamoto T, Watanabe N, Himi T: Expression and localization of TRPV1 in human nasal mucosa. Rhinology (2006) 44(2):128-134.
-
(2006)
Rhinology
, vol.44
, Issue.2
, pp. 128-134
-
-
Seki, N.1
Shirasaki, H.2
Kikuchi, M.3
Sakamoto, T.4
Watanabe, N.5
Himi, T.6
-
74
-
-
0021281734
-
Local and systemic capsaicin pretreatment inhibits sneezing and the increase in nasal vascular permeability induced by certain chemical irritants
-
Lundblad L, Lundberg JM, Anggård A: Local and systemic capsaicin pretreatment inhibits sneezing and the increase in nasal vascular permeability induced by certain chemical irritants. Naunyn Schmiedebergs Arch Pharmacol (1984) 326(3):254-261.
-
(1984)
Naunyn Schmiedebergs Arch. Pharmacol.
, vol.326
, Issue.3
, pp. 254-261
-
-
Lundblad, L.1
Lundberg, J.M.2
Anggård, A.3
-
75
-
-
0023855438
-
Secretion, pain and sneezing induced by the application of capsaicin to the nasal mucosa in man
-
Geppetti P, Fusco BM, Marabini S, Maggi CA, Fanciullacci M, Sicuteri F: Secretion, pain and sneezing induced by the application of capsaicin to the nasal mucosa in man. Br J Pharmacol (1988) 93(3):509-514.
-
(1988)
Br. J. Pharmacol.
, vol.93
, Issue.3
, pp. 509-514
-
-
Geppetti, P.1
Fusco, B.M.2
Marabini, S.3
Maggi, C.A.4
Fanciullacci, M.5
Sicuteri, F.6
-
76
-
-
0028567491
-
Local treatment of aspecific nasal hyperreactivity with capsaicin
-
Filiaci F, Zambetti G, Ciofalo A, Luce M, Masieri S, Lovecchio A: Local treatment of aspecific nasal hyperreactivity with capsaicin. Allergol Immunopathol (1994) 22(6):264-268.
-
(1994)
Allergol. Immunopathol.
, vol.22
, Issue.6
, pp. 264-268
-
-
Filiaci, F.1
Zambetti, G.2
Ciofalo, A.3
Luce, M.4
Masieri, S.5
Lovecchio, A.6
-
77
-
-
0025903504
-
Beneficial effects of intranasal applications of capsaicin in patients with vasomotor rhinitis
-
Marabini S, Ciabatti PG, Polli G, Fusco BM, Geppetti P: Beneficial effects of intranasal applications of capsaicin in patients with vasomotor rhinitis. Eur Arch Otorhinolaryngol (1991) 248(4):191-194.
-
(1991)
Eur. Arch. Otorhinolaryngol.
, vol.248
, Issue.4
, pp. 191-194
-
-
Marabini, S.1
Ciabatti, P.G.2
Polli, G.3
Fusco, B.M.4
Geppetti, P.5
-
78
-
-
0025940005
-
Improvement of symptoms of non-allergic chronic rhinitis by local treatment with capsaicin
-
Lacroix JS, Buvelot JM, Polla BS, Lundberg JM: Improvement of symptoms of non-allergic chronic rhinitis by local treatment with capsaicin. Clin Exp Allergy (1991) 21(5):595-600.
-
(1991)
Clin. Exp. Allergy
, vol.21
, Issue.5
, pp. 595-600
-
-
Lacroix, J.S.1
Buvelot, J.M.2
Polla, B.S.3
Lundberg, J.M.4
-
79
-
-
0030200599
-
Tachykinin and kinin receptor antagonists: Therapeutic perspectives in allergic diease
-
Bertrand C, Geppetti P: Tachykinin and kinin receptor antagonists: Therapeutic perspectives in allergic diease. Trends Pharmacol Sci (1996) 17(7):255-259.
-
(1996)
Trends Pharmacol. Sci.
, vol.17
, Issue.7
, pp. 255-259
-
-
Bertrand, C.1
Geppetti, P.2
-
80
-
-
0028958275
-
Nasal response to capsaicin in patients with allergic rhinitis and in healthy volunteers: Effect of colchicine
-
Roche N, Lurie A, Authier S, Dusser DJ: Nasal response to capsaicin in patients with allergic rhinitis and in healthy volunteers: Effect of colchicine. Am J Respir Crit Care Med (1995) 151(4):1151-1158.
-
(1995)
Am. J. Respir Crit. Care Med.
, vol.151
, Issue.4
, pp. 1151-1158
-
-
Roche, N.1
Lurie, A.2
Authier, S.3
Dusser, D.J.4
-
82
-
-
0020560694
-
Capsaicin induced desensitization of the airway mucosa to cigarette smoke, mechanical and chemical irritants
-
Lundberg J, Saria A: Capsaicin induced desensitization of the airway mucosa to cigarette smoke, mechanical and chemical irritants. Nature (1983) 302(5905):251-253.
-
(1983)
Nature
, vol.302
, Issue.5905
, pp. 251-253
-
-
Lundberg, J.1
Saria, A.2
-
83
-
-
0029658571
-
NK1 receptor antagonist CP-99, 994 inhibits cigarette smoke-induced neutrophil and eosinophil adhesion in rat tracheal venules
-
Baluk P, Bertrand C, Geppetti P, McDonald DM, Nadel JA: NK1 receptor antagonist CP-99, 994 inhibits cigarette smoke-induced neutrophil and eosinophil adhesion in rat tracheal venules. Exp Lung Res (1996) 22(4):409-418.
-
(1996)
Exp. Lung Res.
, vol.22
, Issue.4
, pp. 409-418
-
-
Baluk, P.1
Bertrand, C.2
Geppetti, P.3
McDonald, D.M.4
Nadel, J.A.5
-
84
-
-
50849094871
-
The rabbit as a model to study asthma and other lung diseases
-
Keir S, Page C: The rabbit as a model to study asthma and other lung diseases. Pulm Pharmacol Ther (2008) 21(5):721-730.
-
(2008)
Pulm Pharmacol. Ther.
, vol.21
, Issue.5
, pp. 721-730
-
-
Keir, S.1
Page, C.2
-
85
-
-
0034027359
-
Presence and bronchomotor activity of protease-activated receptor-2 in guinea pig airways
-
Ricciardolo FL, Steinhoff M, Amadesi S, Guerrini R, Tognetto M, Trevisani M, Creminon C, Bertrand C, Bunnett NW, Fabbri LM, Salvadori S et al: Presence and bronchomotor activity of protease-activated receptor-2 in guinea pig airways. Am J Respir Crit Care Med (2000) 161(5):1672-1680.
-
(2000)
Am. J. Respir Crit. Care Med.
, vol.161
, Issue.5
, pp. 1672-1680
-
-
Ricciardolo, F.L.1
Steinhoff, M.2
Amadesi, S.3
Guerrini, R.4
Tognetto, M.5
Trevisani, M.6
Creminon, C.7
Bertrand, C.8
Bunnett, N.W.9
Fabbri, L.M.10
Salvadori, S.11
-
86
-
-
0027140185
-
Involvement of neurogenic inflammation in antigen-induced bronchoconstriction in guinea pigs
-
Bertrand C, Geppetti P, Graf PD, Foresi A, Nadel JA: Involvement of neurogenic inflammation in antigen-induced bronchoconstriction in guinea pigs. Am J Physiol (1993) 265 (5 Pt 1) : L507-L511.
-
(1993)
Am. J. Physiol.
, vol.265
, Issue.1-5 PT.
-
-
Bertrand, C.1
Geppetti, P.2
Graf, P.D.3
Foresi, A.4
Nadel, J.A.5
-
87
-
-
65649115865
-
Long-term outcomes of acute irritant-induced asthma
-
•• Reports that exposure to a series of agents, which had been previously identified as TRPA1 agonists, have the common feature of being able to cause either immediate or enduring asthma-like symptoms
-
Malo JL, L'Archeveque JJ, Castellanos L, Lavoie K, Ghezzo H, Maghni K: Long-term outcomes of acute irritant-induced asthma. Am J Respir Crit Care Med (2009) 179:923-928. •• Reports that exposure to a series of agents, which had been previously identified as TRPA1 agonists, have the common feature of being able to cause either immediate or enduring asthma-like symptoms.
-
(2009)
Am. J. Respir Crit. Care Med.
, vol.179
, pp. 923-928
-
-
Malo, J.L.1
L'Archeveque, J.J.2
Castellanos, L.3
Lavoie, K.4
Ghezzo, H.5
Maghni, K.6
-
88
-
-
0021823772
-
Reactive airways dysfunction syndrome (RADS). Persistent asthma syndrome after high level irritant exposures
-
Brooks SM, Weiss MA, Bernstein IL: Reactive airways dysfunction syndrome (RADS). Persistent asthma syndrome after high level irritant exposures. Chest (1985) 88(3):376-384.
-
(1985)
Chest
, vol.88
, Issue.3
, pp. 376-384
-
-
Brooks, S.M.1
Weiss, M.A.2
Bernstein, I.L.3
-
89
-
-
61849085255
-
Occupational asthma: Current concepts in pathogenesis, diagnosis, and management
-
Dykewicz MS: Occupational asthma: Current concepts in pathogenesis, diagnosis, and management. J Allergy Clin Immunol (2009) 123(3):519-528.
-
(2009)
J. Allergy Clin. Immunol.
, vol.123
, Issue.3
, pp. 519-528
-
-
Dykewicz, M.S.1
-
90
-
-
43049090817
-
TRPA1 is a major oxidant sensor in murine airway sensory neurons
-
• Summarizes the identification of TRPA1 as the sensor of oxidative stress
-
Bessac BF, Sivula M, von Hehn CA, Escalera J, Cohn L, Jordt SE: TRPA1 is a major oxidant sensor in murine airway sensory neurons. J Clin Invest (2008) 118(5):1899-1910. • Summarizes the identification of TRPA1 as the sensor of oxidative stress.
-
(2008)
J. Clin. Invest.
, vol.118
, Issue.5
, pp. 1899-1910
-
-
Bessac, B.F.1
Sivula, M.2
Von Hehn, C.A.3
Escalera, J.4
Cohn, L.5
Jordt, S.E.6
-
91
-
-
63849101712
-
Nitrooleic acid, an endogenous product of nitrative stress, activates nociceptive sensory nerves via the direct activation of TRPA1
-
•• Reports that nitro-oleic acid, which is a byproduct of nitrative stress, is a TRPA1 agonist
-
Taylor-Clark TE, Ghatta S, Bettner W, Undem BJ: Nitrooleic acid, an endogenous product of nitrative stress, activates nociceptive sensory nerves via the direct activation of TRPA1. Mol Pharmacol (2009) 75(4):820-829. •• Reports that nitro-oleic acid, which is a byproduct of nitrative stress, is a TRPA1 agonist.
-
(2009)
Mol. Pharmacol.
, vol.75
, Issue.4
, pp. 820-829
-
-
Taylor-Clark, T.E.1
Ghatta, S.2
Bettner, W.3
Undem, B.J.4
-
92
-
-
65349163523
-
Transient receptor potential ankyrin 1 antagonists block the noxious effects of toxic industrial isocyanates and tear gases
-
Bessac BF, Sivula M, von Hehn CA, Caceres AI, Escalera J, Jordt SE: Transient receptor potential ankyrin 1 antagonists block the noxious effects of toxic industrial isocyanates and tear gases. FASEB J (2009) 23(4):1102-1114.
-
(2009)
FASEB J.
, vol.23
, Issue.4
, pp. 1102-1114
-
-
Bessac, B.F.1
Sivula, M.2
Von Hehn, C.A.3
Caceres, A.I.4
Escalera, J.5
Jordt, S.E.6
-
93
-
-
63849217721
-
Transient receptor potential ankyrin 1 mediates toluene diisocyanate-evoked respiratory irritation
-
Taylor-Clark TE, Kiros F, Carr MJ, McAlexander MA: Transient receptor potential ankyrin 1 mediates toluene diisocyanate-evoked respiratory irritation. Am J Respir Cell Mol Biol (2008) 40(6):756-762.
-
(2008)
Am. J. Respir Cell. Mol. Biol.
, vol.40
, Issue.6
, pp. 756-762
-
-
Taylor-Clark, T.E.1
Kiros, F.2
Carr, M.J.3
McAlexander, M.A.4
-
94
-
-
0027931460
-
Capsaicin reduces ozone-induced airway inflammation in guinea pigs
-
Kaneko T, Ikeda H, Fu L, Nishiyama H, Matsuoka M, Yamakawa HO, Okubo T: Capsaicin reduces ozone-induced airway inflammation in guinea pigs. Am J Respir Crit Care Med (1994) 150(3):724-728.
-
(1994)
Am. J. Respir Crit. Care Med.
, vol.150
, Issue.3
, pp. 724-728
-
-
Kaneko, T.1
Ikeda, H.2
Fu, L.3
Nishiyama, H.4
Matsuoka, M.5
Yamakawa, H.O.6
Okubo, T.7
-
95
-
-
0028953863
-
Plasma extravasation in the rat trachea induced by cold air is mediated by tachykinin release from sensory nerves
-
Yoshihara S, Chan B, Yamawaki I, Geppetti P, Ricciardolo FL, Massion PP, Nadel JA: Plasma extravasation in the rat trachea induced by cold air is mediated by tachykinin release from sensory nerves. Am J Respir Crit Care Med (1995) 151(4):1011-1017.
-
(1995)
Am. J. Respir Crit. Care Med.
, vol.151
, Issue.4
, pp. 1011-1017
-
-
Yoshihara, S.1
Chan, B.2
Yamawaki, I.3
Geppetti, P.4
Ricciardolo, F.L.5
Massion, P.P.6
Nadel, J.A.7
-
96
-
-
0033047557
-
Bronchoconstriction induced by citric acid inhalation in guinea pigs: Role of tachykinins, bradykinin, and nitric oxide
-
Ricciardolo FL, Rado V, Fabbri LM, Sterk PJ, Di Maria GU, Geppetti P: Bronchoconstriction induced by citric acid inhalation in guinea pigs: Role of tachykinins, bradykinin, and nitric oxide. Am J Respir Crit Care Med (1999) 159(2):557-562.
-
(1999)
Am. J. Respir Crit. Care Med.
, vol.159
, Issue.2
, pp. 557-562
-
-
Ricciardolo, F.L.1
Rado, V.2
Fabbri, L.M.3
Sterk, P.J.4
Maria, G.U.D.5
Geppetti, P.6
-
97
-
-
66749097274
-
Bronchoconstriction induced by hyperventilation with humidifed hot air: Role of TRPV1-expressing airway afferents
-
Lin RL, Hayes D Jr, Lee LY: Bronchoconstriction induced by hyperventilation with humidifed hot air: Role of TRPV1-expressing airway afferents. J Appl Physiol (2009) 106(6):1917-1924.
-
(2009)
J. Appl. Physiol.
, vol.106
, Issue.6
, pp. 1917-1924
-
-
Lin, R.L.1
Hayes Jr., D.2
Lee, L.Y.3
-
98
-
-
0027103748
-
Inhibition of low pH evoked activation of airway sensory nerves by capsazepine, a novel capsaicin-receptor antagonist
-
Lou YP, Lundberg JM: Inhibition of low pH evoked activation of airway sensory nerves by capsazepine, a novel capsaicin-receptor antagonist. Biochem Biophys Res Commun (1992) 189(1):537-544.
-
(1992)
Biochem. Biophys. Res. Commun.
, vol.189
, Issue.1
, pp. 537-544
-
-
Lou, Y.P.1
Lundberg, J.M.2
-
100
-
-
0035989762
-
Tachykinins and airway microvascular leakage induced by HCl intra-oesophageal instillation
-
Daoui S, D'Agostino B, Gallelli L, Alt XE, Rossi F, Advenier C: Tachykinins and airway microvascular leakage induced by HCl intra-oesophageal instillation. Eur Respir J (2002) 20(2):268-273.
-
(2002)
Eur. Respir J.
, vol.20
, Issue.2
, pp. 268-273
-
-
Daoui, S.1
D'Agostino, B.2
Gallelli, L.3
Alt, X.E.4
Rossi, F.5
Advenier, C.6
-
101
-
-
9644289444
-
Gastroesophageal refux: A potential asthma trigger
-
Harding SM: Gastroesophageal refux: A potential asthma trigger. Immunol Allergy Clin North Am (2005) 25(1):131-148.
-
(2005)
Immunol. Allergy Clin. North Am.
, vol.25
, Issue.1
, pp. 131-148
-
-
Harding, S.M.1
-
102
-
-
0034636441
-
Vanilloid receptor-1 is essential for inflammatory thermal hyperalgesia
-
Davis JB, Gray J, Gunthorpe MJ, Hatcher JP, Davey PT, Overend P, Harries MH, Latcham J, Clapham C, Atkinson K, Hughes SA et al: Vanilloid receptor-1 is essential for inflammatory thermal hyperalgesia. Nature (2000) 405(6783):183-187.
-
(2000)
Nature
, vol.405
, Issue.6783
, pp. 183-187
-
-
Davis, J.B.1
Gray, J.2
Gunthorpe, M.J.3
Hatcher, J.P.4
Davey, P.T.5
Overend, P.6
Harries, M.H.7
Latcham, J.8
Clapham, C.9
Atkinson, K.10
Hughes, S.A.11
-
103
-
-
0037215646
-
The VR1 antagonist capsazepine reverses mechanical hyperalgesia in models of inflammatory and neuropathic pain
-
Walker KM, Urban L, Medhurst SJ, Patel S, Panesar M, Fox AJ, McIntyre P: The VR1 antagonist capsazepine reverses mechanical hyperalgesia in models of inflammatory and neuropathic pain. J Pharmacol Exp Ther (2003) 304(1):56-62.
-
(2003)
J. Pharmacol. Exp. Ther.
, vol.304
, Issue.1
, pp. 56-62
-
-
Walker, K.M.1
Urban, L.2
Medhurst, S.J.3
Patel, S.4
Panesar, M.5
Fox, A.J.6
McIntyre, P.7
-
104
-
-
67649482336
-
Activation of TRPV1 and TRPA1 leads to muscle nociception and mechanical hyperalgesia
-
Ro JY, Lee JS, Zhang Y: Activation of TRPV1 and TRPA1 leads to muscle nociception and mechanical hyperalgesia. Pain (2009) 144(3):270-277.
-
(2009)
Pain
, vol.144
, Issue.3
, pp. 270-277
-
-
Ro, J.Y.1
Lee, J.S.2
Zhang, Y.3
-
105
-
-
65549123596
-
TRPA1 modulates mechanotransduction in cutaneous sensory neurons
-
Kwan KY, Glazer JM, Corey DP, Rice FL, Stucky CL: TRPA1 modulates mechanotransduction in cutaneous sensory neurons. J Neurosci (2009) 29(15):4808-4819.
-
(2009)
J. Neurosci.
, vol.29
, Issue.15
, pp. 4808-4819
-
-
Kwan, K.Y.1
Glazer, J.M.2
Corey, D.P.3
Rice, F.L.4
Stucky, C.L.5
-
106
-
-
84965360688
-
The nocifensor system of nerves and its reactions
-
Lewis T: The nocifensor system of nerves and its reactions. BMJ (1937) 1(3974):491-494.
-
(1937)
BMJ
, vol.1
, Issue.3974
, pp. 491-494
-
-
Lewis, T.1
-
107
-
-
33947732192
-
Role of capsaicin-sensitive afferents and sensory neuropeptides in endotoxin-induced airway inflammation and consequent bronchial hyperreactivity in the mouse
-
Elekes K, Helyes Z, Németh J, Sándor K, Pozsgai G, Kereskai L, Börzsei R, Pintér E, Szabó A, Szolcsányi J: Role of capsaicin-sensitive afferents and sensory neuropeptides in endotoxin-induced airway inflammation and consequent bronchial hyperreactivity in the mouse. Regul Pept (2007) 141 (1-3) : 44-54.
-
(2007)
Regul Pept
, vol.141
, Issue.1-3
, pp. 44-54
-
-
Elekes, K.1
Helyes, Z.2
Németh, J.3
Sándor, K.4
Pozsgai, G.5
Kereskai, L.6
Börzsei, R.7
Pintér, E.8
Szabó, A.9
Szolcsányi, J.10
-
108
-
-
34248138496
-
The vanilloid receptor TRPV1:10 years from channel cloning to antagonist proof-of-concept
-
Szallasi A, Cortright DN, Blum CA, Eid SR: The vanilloid receptor TRPV1:10 years from channel cloning to antagonist proof-of-concept. Nat Rev Drug Discov (2007) 6(5):357-372.
-
(2007)
Nat. Rev. Drug Discov.
, vol.6
, Issue.5
, pp. 357-372
-
-
Szallasi, A.1
Cortright, D.N.2
Blum, C.A.3
Eid, S.R.4
-
109
-
-
34548101399
-
TRPA1 mediates formalin-induced pain
-
•• Demonstrated that the first selective TRPA1 antagonist, HC-030031, could abate the first and second phases of the formalin-evoked nociceptive response ie, the formalin test for nociception
-
McNamara CR, Mandel-Brehm J, Bautista DM, Siemens J, Deranian KL, Zhao M, Hayward NJ, Chong JA, Julius D, Moran MM, Fanger CM: TRPA1 mediates formalin-induced pain. Proc Natl Acad Sci USA (2007) 104(33):13525-13530. •• Demonstrated that the first selective TRPA1 antagonist, HC-030031, could abate the first and second phases of the formalin-evoked nociceptive response (ie, the formalin test for nociception).
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, Issue.33
, pp. 13525-13530
-
-
McNamara, C.R.1
Mandel-Brehm, J.2
Bautista, D.M.3
Siemens, J.4
Deranian, K.L.5
Zhao, M.6
Hayward, N.J.7
Chong, J.A.8
Julius, D.9
Moran, M.M.10
Fanger, C.M.11
|