New limonene-hybrid derivatives with anti-T. cruzi activity

Letters in Drug Design and Discovery

Volumn 7, Issue 6, 2010, Pages 452-460

  Alvarez G ^a   Gerpe, A ^a   Benitez, D ^a   Garibotto, F ^b   Zacchino, S ^b   Graebin, C S ^c   Gomes da Rosa, R ^c   Eifler Lima, V L ^c   Gonzalez M ^a   Cerecetto, H ^a  

^a UNIVERSIDAD DE LA REPÚBLICA   (Uruguay)

^b UNIVERSIDAD NACIONAL DE ROSARIO   (Argentina)

^c FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

Author keywords

5 nitrofuran; 5 nitroindazole; Anti T. cruzi agents; Antifungal; Limonene derivatives; Lipinski rule

Indexed keywords

2,2 DIMETHYL 5 {N [3 (4 METHYL 3 CICLOHEXENYL)BUTYL]N PROPYLAMINO}METHYL 2H BENZIMIDAZOLE 1,3 DIOXIDE; 3 (4 METHYL 3 CICLOHEXENYL) N [5 (3 METHOXY 5 NITRO 1H INDAZOLE 1 YL) 3 OXAPENTYL] N PROPYLBUTANEAMINE; 5 {N [3 (4 METHYL 3 CYCLOHEXENYL)BUTYL] N PROPYLAMINO} METHYLBENZOFUROXAN; ANTIFUNGAL AGENT; ANTITRYPANOSOMAL AGENT; ERGOSTEROL; FREE RADICAL; FUNGICIDE; INDAZOLE DERIVATIVE; LIMONENE; N [3 (4 METHYL 3 CICLOHEXENYL)BUTYL] 3 (5 NITROFURAN 2 YL) N PROPYLPROPENAMIDE; N [5 (3 BENZYLOXY 5 NITRO 1H INDAZOLE 1 YL) 3 OXAPENTYL] 3 (4 METHYL 3 CICLOHEXENYL) N PROPYLBUTANEAMINE; N [5 (3 BENZYLOXY 5 NITRO 1H INDAZOLE 1 YL)PENTYL] 3 (4 METHYL 3 CICLOHEXENYL) N PROPYLBUTANEAMINE; NITROFURAN DERIVATIVE; SQUALENE; STEROL; UNCLASSIFIED DRUG;

ANTIFUNGAL ACTIVITY; ARTICLE; BIOLOGICAL ACTIVITY; CHEMICAL STRUCTURE; CONTROLLED STUDY; DRUG MECHANISM; GROWTH INHIBITION; HYBRID; IN VITRO STUDY; LIPOPHILICITY; MEMBRANE; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; TRYPANOSOMA CRUZI;

EID: 77952135696     PISSN: 15701808     EISSN: None     Source Type: Journal    
DOI: 10.2174/157018010791306524     Document Type: Article

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