Changes related to phosphatidylinositol 3-kinase/Akt signaling in leiomyomas: possible involvement of glycogen synthase kinase 3α and cyclin D2 in the pathophysiology

Fertility and Sterility

Volumn 93, Issue 8, 2010, Pages 2646-2651

  Karra, Laila ^a   Shushan, Asher ^a   Ben Meir, Assaf ^a   Rojansky, Nathan ^a   Klein, Benjamin Y ^a   Shveiky, David ^a   Levitzki, Rubina ^a   Ben Bassat, Hanna ^a  

^a HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

Author keywords

cell survival; cyclin D2; GSK3; PI3K Akt; signal transduction; Uterine leiomyomas

Indexed keywords

CYCLIN D2; GLYCOGEN SYNTHASE KINASE 3ALPHA; HAMARTIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE 1; PROTEIN KINASE B; TRANSCRIPTION FACTOR FKHR; TUBERIN;

ADULT; AMINO TERMINAL SEQUENCE; APOPTOSIS; ARTICLE; CELL CYCLE G1 PHASE; CELL CYCLE PROGRESSION; CELL CYCLE S PHASE; CELL GROWTH; CELL SURVIVAL; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; HYSTERECTOMY; IMMUNOHISTOCHEMISTRY; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; UTERUS MYOMA;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ADULT; CYCLIN D2; FEMALE; GLYCOGEN SYNTHASE KINASE 3; HUMANS; LEIOMYOMA; MIDDLE AGED; MYOMETRIUM; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; SIGNAL TRANSDUCTION; UTERINE NEOPLASMS;

EID: 77952109487     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2009.03.100     Document Type: Article

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