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Volumn 14, Issue 5-6, 2008, Pages 264-275

Differential expression of receptor tyrosine kinases (RTKs) and IGF-I pathway activation in human uterine leiomyomas

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR RECEPTOR; GROWTH FACTOR RECEPTOR BOUND PROTEIN 2; INSULIN RECEPTOR SUBSTRATE 1; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NEUTRALIZING ANTIBODY; PHOSPHATIDYLINOSITOL 3 KINASE; PLATELET DERIVED GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR RECEPTOR; PROTEIN KINASE B; PROTEIN SHC; PROTEIN TYROSINE KINASE; SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR;

EID: 44649107576     PISSN: 10761551     EISSN: None     Source Type: Journal    
DOI: 10.2119/2007-00101.Yu     Document Type: Article
Times cited : (77)

References (48)
  • 2
    • 27844487407 scopus 로고    scopus 로고
    • The economic impact of uterine fibroids in the United States: A summary of published estimates
    • Mauskopf J, Flynn M, Thieda P, Spalding J, Duchane J. (2005) The economic impact of uterine fibroids in the United States: a summary of published estimates. J. Womens Health. (Larchmt) 14:692-703.
    • (2005) J. Womens Health. (Larchmt) , vol.14 , pp. 692-703
    • Mauskopf, J.1    Flynn, M.2    Thieda, P.3    Spalding, J.4    Duchane, J.5
  • 3
    • 4344563483 scopus 로고    scopus 로고
    • Uterine myomas: An overview of development, clinical features, and management
    • Wallach EE, Vlahos NF. (2004) Uterine myomas: an overview of development, clinical features, and management. Obstet. Gynecol. 104:393-406.
    • (2004) Obstet. Gynecol , vol.104 , pp. 393-406
    • Wallach, E.E.1    Vlahos, N.F.2
  • 5
    • 0033675860 scopus 로고    scopus 로고
    • Immunohistochemical localization of growth factors and their receptors in uterine leiomyomas and matched myometrium
    • Dixon D, He H, Haseman JK. (2000) Immunohistochemical localization of growth factors and their receptors in uterine leiomyomas and matched myometrium. Environ. Health Perspect. 108 Suppl 5:795-802.
    • (2000) Environ. Health Perspect , vol.108 , Issue.SUPPL. 5 , pp. 795-802
    • Dixon, D.1    He, H.2    Haseman, J.K.3
  • 7
    • 20444389034 scopus 로고    scopus 로고
    • Uterine fibroids: The elephant in the room
    • Walker CL, Stewart EA. (2005) Uterine fibroids: the elephant in the room. Science. 308:1589-92.
    • (2005) Science , vol.308 , pp. 1589-1592
    • Walker, C.L.1    Stewart, E.A.2
  • 8
    • 0037677597 scopus 로고    scopus 로고
    • Etiology and pathogenesis of uterine leiomyomas: A review
    • Flake GP, Andersen J, Dixon D. (2003) Etiology and pathogenesis of uterine leiomyomas: a review. Environ. Health Perspect. 111:1037-54.
    • (2003) Environ. Health Perspect , vol.111 , pp. 1037-1054
    • Flake, G.P.1    Andersen, J.2    Dixon, D.3
  • 10
    • 13244269807 scopus 로고    scopus 로고
    • Expression profile of tuberin and some potential tumorigenic factors in 60 patients with uterine leiomyomata
    • Wei J, Chiriboga L, Mizuguchi M, Yee H, Mittal K. (2005) Expression profile of tuberin and some potential tumorigenic factors in 60 patients with uterine leiomyomata. Mod. Pathol. 18:179-88.
    • (2005) Mod. Pathol , vol.18 , pp. 179-188
    • Wei, J.1    Chiriboga, L.2    Mizuguchi, M.3    Yee, H.4    Mittal, K.5
  • 11
    • 0027515736 scopus 로고
    • Insulin-like growth factor (IGF), IGF binding protein (IGFBP), and IGF receptor gene expression and IGFBP synthesis in human uterine leiomyomata
    • Giudice LC et al. (1993) Insulin-like growth factor (IGF), IGF binding protein (IGFBP), and IGF receptor gene expression and IGFBP synthesis in human uterine leiomyomata. Hum. Reprod. 8:1796-806.
    • (1993) Hum. Reprod , vol.8 , pp. 1796-1806
    • Giudice, L.C.1
  • 12
    • 0029119731 scopus 로고
    • Insulin-like growth factor-I receptor. Its role in cell proliferation, apoptosis, and tumorigenicity
    • Rubin R, Baserga R. (1995) Insulin-like growth factor-I receptor. Its role in cell proliferation, apoptosis, and tumorigenicity. Lab. Invest. 73:311-31.
    • (1995) Lab. Invest , vol.73 , pp. 311-331
    • Rubin, R.1    Baserga, R.2
  • 13
    • 0037300604 scopus 로고    scopus 로고
    • The IGFI receptor gene: A molecular target for disrupted transcription factors
    • Werner H, Roberts CT Jr. (2003) The IGFI receptor gene: a molecular target for disrupted transcription factors. Genes Chromosomes Cancer 36:113-120.
    • (2003) Genes Chromosomes Cancer , vol.36 , pp. 113-120
    • Werner, H.1    Roberts Jr., C.T.2
  • 14
    • 16544384123 scopus 로고    scopus 로고
    • IGF-I receptor, cell-cell adhesion, tumor development and progression
    • Mauro L, Surmacz E. (2004) IGF-I receptor, cell-cell adhesion, tumor development and progression. J. Mol. Histol. 35:247-53.
    • (2004) J. Mol. Histol , vol.35 , pp. 247-253
    • Mauro, L.1    Surmacz, E.2
  • 15
    • 24944512406 scopus 로고    scopus 로고
    • Estrogen-induced changes in IGF-I, Myb family and MAP kinase pathway genes in human uterine leiomyoma and normal uterine smooth muscle cell lines
    • Swartz CD, Afshari CA, Yu L, Hall KE, Dixon D. (2005) Estrogen-induced changes in IGF-I, Myb family and MAP kinase pathway genes in human uterine leiomyoma and normal uterine smooth muscle cell lines. Mol. Hum. Reprod. 11:441-50.
    • (2005) Mol. Hum. Reprod , vol.11 , pp. 441-450
    • Swartz, C.D.1    Afshari, C.A.2    Yu, L.3    Hall, K.E.4    Dixon, D.5
  • 16
    • 0020334316 scopus 로고
    • Analysis of covariance using the rank transformation
    • Conover WJ, Iman RL. (1982) Analysis of covariance using the rank transformation. Biometrics. 38:715-24.
    • (1982) Biometrics , vol.38 , pp. 715-724
    • Conover, W.J.1    Iman, R.L.2
  • 17
    • 18744410984 scopus 로고    scopus 로고
    • Gene expression studies provide clues to the pathogenesis of uterine leiomyoma: New evidence and a systematic review
    • Arslan AA et al. (2005) Gene expression studies provide clues to the pathogenesis of uterine leiomyoma: new evidence and a systematic review. Hum. Reprod. 20:852-63.
    • (2005) Hum. Reprod , vol.20 , pp. 852-863
    • Arslan, A.A.1
  • 18
    • 0036305538 scopus 로고    scopus 로고
    • Cell proliferation and apoptosis in human uterine leiomyomas and myometria
    • Dixon D et al. (2002) Cell proliferation and apoptosis in human uterine leiomyomas and myometria. Virchows Arch. 441:53-62.
    • (2002) Virchows Arch , vol.441 , pp. 53-62
    • Dixon, D.1
  • 19
    • 33745855890 scopus 로고    scopus 로고
    • A novel selective progesterone receptor modulator asoprisnil (J867) down-regulates the expression of EGF, IGF-I, TGFbeta3 and their receptors in cultured uterine leiomyoma cells
    • Wang J et al. (2006) A novel selective progesterone receptor modulator asoprisnil (J867) down-regulates the expression of EGF, IGF-I, TGFbeta3 and their receptors in cultured uterine leiomyoma cells. Hum. Reprod. 21:1869-77.
    • (2006) Hum. Reprod , vol.21 , pp. 1869-1877
    • Wang, J.1
  • 20
    • 0028212465 scopus 로고
    • Quantification of messenger ribonucleic acid for epidermal growth factor in human myometrium and leiomyomata using reverse transcriptase polymerase chain reaction
    • Harrison-Woolrych ML, Charnock-Jones DS, Smith SK. (1994) Quantification of messenger ribonucleic acid for epidermal growth factor in human myometrium and leiomyomata using reverse transcriptase polymerase chain reaction. J. Clin. Endocrinol. Metab. 78:1179-84.
    • (1994) J. Clin. Endocrinol. Metab , vol.78 , pp. 1179-1184
    • Harrison-Woolrych, M.L.1    Charnock-Jones, D.S.2    Smith, S.K.3
  • 21
    • 0026488235 scopus 로고
    • Biology of uterine myomas and myometrium in vitro
    • Rein MS, Nowak RA. (1992) Biology of uterine myomas and myometrium in vitro. Semin. Reprod. Endocrinol. 10:310-9.
    • (1992) Semin. Reprod. Endocrinol , vol.10 , pp. 310-319
    • Rein, M.S.1    Nowak, R.A.2
  • 22
    • 0031763790 scopus 로고    scopus 로고
    • Up-regulation by progesterone of proliferating cell nuclear antigen and epidermal growth factor expression in human uterine leiomyoma
    • Shimomura Y, Matsuo H, Samoto T, Maruo T. (1998) Up-regulation by progesterone of proliferating cell nuclear antigen and epidermal growth factor expression in human uterine leiomyoma. J. Clin. Endocrinol. Metab. 83:2192-8.
    • (1998) J. Clin. Endocrinol. Metab , vol.83 , pp. 2192-2198
    • Shimomura, Y.1    Matsuo, H.2    Samoto, T.3    Maruo, T.4
  • 23
    • 0029957296 scopus 로고    scopus 로고
    • Leiomyoma-related bleeding: A classic hypothesis updated for the molecular era
    • Stewart EA, Nowak RA. (1996) Leiomyoma-related bleeding: a classic hypothesis updated for the molecular era. Hum. Reprod. Update. 2:295-306.
    • (1996) Hum. Reprod. Update , vol.2 , pp. 295-306
    • Stewart, E.A.1    Nowak, R.A.2
  • 24
    • 0029097356 scopus 로고
    • Isolation and characterization of heparin-binding growth factors in human leiomyomas and normal myometrium
    • Mangrulkar RS, Ono M, Ishikawa M, Takashima S, Klagsbrun M, Nowak RA. (1995) Isolation and characterization of heparin-binding growth factors in human leiomyomas and normal myometrium. Biol. Reprod. 53:636-46.
    • (1995) Biol. Reprod , vol.53 , pp. 636-646
    • Mangrulkar, R.S.1    Ono, M.2    Ishikawa, M.3    Takashima, S.4    Klagsbrun, M.5    Nowak, R.A.6
  • 25
    • 27944492881 scopus 로고    scopus 로고
    • Fibroblast growth factors (FGF) in human myometrium and uterine leiomyomas in various stages of tumor growth
    • Wolanska M, Bankowski E. (2006) Fibroblast growth factors (FGF) in human myometrium and uterine leiomyomas in various stages of tumor growth. Biochimie. 88:141-6.
    • (2006) Biochimie , vol.88 , pp. 141-146
    • Wolanska, M.1    Bankowski, E.2
  • 26
    • 0024595717 scopus 로고
    • Human uterine leiomyoma cells: Binding and growth responses to epidermal growth factor, platelet-derived growth factor, and insulin
    • Fayed YM, Tsibris JC, Langenberg PW, Robertson AL Jr. (1989) Human uterine leiomyoma cells: binding and growth responses to epidermal growth factor, platelet-derived growth factor, and insulin. Lab. Invest. 60:30-7.
    • (1989) Lab. Invest , vol.60 , pp. 30-37
    • Fayed, Y.M.1    Tsibris, J.C.2    Langenberg, P.W.3    Robertson Jr., A.L.4
  • 27
    • 32544448224 scopus 로고    scopus 로고
    • Expression and functional analysis of platelet-derived growth factor in uterine leiomyomata
    • Liang M, Wang H, Zhang Y, Lu S, Wang Z. (2006) Expression and functional analysis of platelet-derived growth factor in uterine leiomyomata. Cancer Biol. Ther. 5:28-33.
    • (2006) Cancer Biol. Ther , vol.5 , pp. 28-33
    • Liang, M.1    Wang, H.2    Zhang, Y.3    Lu, S.4    Wang, Z.5
  • 28
    • 33846244271 scopus 로고    scopus 로고
    • Transforming growth factor beta and platelet-derived growth factor in human myometrium and in uterine leiomyomas at various stages of tumor growth
    • Wolanska M, Bankowski E. (2007) Transforming growth factor beta and platelet-derived growth factor in human myometrium and in uterine leiomyomas at various stages of tumor growth. Eur. J. Obstet. Gynecol. Reprod. Biol. 130:238-44.
    • (2007) Eur. J. Obstet. Gynecol. Reprod. Biol , vol.130 , pp. 238-244
    • Wolanska, M.1    Bankowski, E.2
  • 29
    • 0025077575 scopus 로고
    • Expression of the insulin-like and platelet-derived growth factor genes in human uterine tissues
    • Boehm KD, Daimon M, Gorodeski IG, Sheean LA, Utian WH, Ilan J. (1990) Expression of the insulin-like and platelet-derived growth factor genes in human uterine tissues. Mol. Reprod. Dev. 27:93-101.
    • (1990) Mol. Reprod. Dev , vol.27 , pp. 93-101
    • Boehm, K.D.1    Daimon, M.2    Gorodeski, I.G.3    Sheean, L.A.4    Utian, W.H.5    Ilan, J.6
  • 30
    • 0024006721 scopus 로고
    • Expression of insulin-like growth factor-I and -II genes in human smooth muscle tumours
    • Hoppener JW et al. (1988) Expression of insulin-like growth factor-I and -II genes in human smooth muscle tumours. Embo. J. 7:1379-85.
    • (1988) Embo. J , vol.7 , pp. 1379-1385
    • Hoppener, J.W.1
  • 31
    • 15444365353 scopus 로고    scopus 로고
    • Gene expression and tyrosine kinase activity of insulin receptor in uterine leiomyoma and matched myometrium
    • Toscani GK et al. (2004) Gene expression and tyrosine kinase activity of insulin receptor in uterine leiomyoma and matched myometrium. Arch. Gynecol. Obstet. 270:170-3.
    • (2004) Arch. Gynecol. Obstet , vol.270 , pp. 170-173
    • Toscani, G.K.1
  • 32
    • 0024438039 scopus 로고
    • Binding of epidermal growth factor and insulin-like growth factor I in human myometrium and leiomyomata
    • Tommola P, Pekonen F, Rutanen EM. (1989) Binding of epidermal growth factor and insulin-like growth factor I in human myometrium and leiomyomata. Obstet. Gynecol. 74:658-62.
    • (1989) Obstet. Gynecol , vol.74 , pp. 658-662
    • Tommola, P.1    Pekonen, F.2    Rutanen, E.M.3
  • 33
  • 34
    • 0030998199 scopus 로고    scopus 로고
    • Expression of insulin-like growth factors (IGFs), their receptors and IGF binding protein-3 in normal, benign and malignant smooth muscle tissues
    • Van der Ven LT et al. (1997) Expression of insulin-like growth factors (IGFs), their receptors and IGF binding protein-3 in normal, benign and malignant smooth muscle tissues. Br. J. Cancer. 75:1631-40.
    • (1997) Br. J. Cancer , vol.75 , pp. 1631-1640
    • Van der Ven, L.T.1
  • 35
    • 0034644539 scopus 로고    scopus 로고
    • Cell signaling by receptor tyrosine kinases
    • Schlessinger J. (2000) Cell signaling by receptor tyrosine kinases. Cell. 103:211-25.
    • (2000) Cell , vol.103 , pp. 211-225
    • Schlessinger, J.1
  • 36
    • 0002254373 scopus 로고    scopus 로고
    • The IGF-I Receptor in Normal and Abnormal Growth
    • Dickson RB, Salomon DS ed, Wiley-Liss Inc, Wilmington, DE, pp
    • Baserga R. (1998) The IGF-I Receptor in Normal and Abnormal Growth. In: Hormones and Growth Factors in Development and Neoplasia. Dickson RB, Salomon DS (ed.) Wiley-Liss Inc, Wilmington, DE, pp. 269-87.
    • (1998) Hormones and Growth Factors in Development and Neoplasia , pp. 269-287
    • Baserga, R.1
  • 37
    • 0028067989 scopus 로고
    • Growth advantage of human leiomyoma cells compared to normal smooth-muscle cells due to enhanced sensitivity toward insulin-like growth factor I
    • van der Ven LT et al. (1994) Growth advantage of human leiomyoma cells compared to normal smooth-muscle cells due to enhanced sensitivity toward insulin-like growth factor I. Int. J. Cancer. 59:427-34.
    • (1994) Int. J. Cancer , vol.59 , pp. 427-434
    • van der Ven, L.T.1
  • 38
    • 0033808363 scopus 로고    scopus 로고
    • Gene expression and tissue concentrations of IGF-I in human myometrium and fibroids under different hormonal conditions
    • Englund K, Lindblom B, Carlstrom K, Gustavsson I, Sjoblom P, Blanck A. (2000) Gene expression and tissue concentrations of IGF-I in human myometrium and fibroids under different hormonal conditions. Mol. Hum. Reprod. 6:915-20.
    • (2000) Mol. Hum. Reprod , vol.6 , pp. 915-920
    • Englund, K.1    Lindblom, B.2    Carlstrom, K.3    Gustavsson, I.4    Sjoblom, P.5    Blanck, A.6
  • 39
    • 12344307176 scopus 로고    scopus 로고
    • An accumulation of insulin-like growth factor I (IGF-I) in human myometrium and uterine leiomyomas in various stages of tumour growth
    • Wolanska M, Bankowski E. (2004) An accumulation of insulin-like growth factor I (IGF-I) in human myometrium and uterine leiomyomas in various stages of tumour growth. Eur. Cytokine Netw. 15:359-63.
    • (2004) Eur. Cytokine Netw , vol.15 , pp. 359-363
    • Wolanska, M.1    Bankowski, E.2
  • 40
    • 0346725862 scopus 로고    scopus 로고
    • Regulation of IGF-I receptor signaling in tumor cells
    • O'Connor R. (2003) Regulation of IGF-I receptor signaling in tumor cells. Horm. Metab. Res. 35:771-7.
    • (2003) Horm. Metab. Res , vol.35 , pp. 771-777
    • O'Connor, R.1
  • 42
    • 0242624594 scopus 로고    scopus 로고
    • Growth factor receptors as therapeutic targets: Strategies to inhibit the insulin-like growth factor I receptor
    • Surmacz E. (2003) Growth factor receptors as therapeutic targets: strategies to inhibit the insulin-like growth factor I receptor. Oncogene. 22:6589-97.
    • (2003) Oncogene , vol.22 , pp. 6589-6597
    • Surmacz, E.1
  • 43
    • 17744405954 scopus 로고    scopus 로고
    • Differential expression of Akt/protein kinase B, Bcl-2 and Bax proteins in human leiomyoma and myometrium
    • Kovacs KA et al. (2003) Differential expression of Akt/protein kinase B, Bcl-2 and Bax proteins in human leiomyoma and myometrium. J. Steroid Biochem. Mol. Biol. 87:233-40.
    • (2003) J. Steroid Biochem. Mol. Biol , vol.87 , pp. 233-240
    • Kovacs, K.A.1
  • 44
    • 33846437521 scopus 로고    scopus 로고
    • Phosphorylation of PTEN (phosphatase and tensin homologue deleted on chromosome ten) protein is enhanced in human fibromyomatous uteri
    • Kovacs KA et al. (2007) Phosphorylation of PTEN (phosphatase and tensin homologue deleted on chromosome ten) protein is enhanced in human fibromyomatous uteri. J. Steroid Biochem. Mol. Biol. 103:196-9.
    • (2007) J. Steroid Biochem. Mol. Biol , vol.103 , pp. 196-199
    • Kovacs, K.A.1
  • 45
    • 0023655764 scopus 로고
    • Molecular cloning of gene sequences that are regulated by insulin-like growth factor I
    • Zumstein P, Stiles CD. (1987) Molecular cloning of gene sequences that are regulated by insulin-like growth factor I. J. Biol. Chem. 262:11252-60.
    • (1987) J. Biol. Chem , vol.262 , pp. 11252-11260
    • Zumstein, P.1    Stiles, C.D.2
  • 46
    • 0029036589 scopus 로고    scopus 로고
    • Strawn EY, Jr., Novy MJ, Burry KA, Bethea CL. (1995) Insulin-like growth factor I promotes leiomyoma cell growth in vitro. Am. J. Obstet. Gynecol. 172:1837-43; discussion 1843-4.
    • Strawn EY, Jr., Novy MJ, Burry KA, Bethea CL. (1995) Insulin-like growth factor I promotes leiomyoma cell growth in vitro. Am. J. Obstet. Gynecol. 172:1837-43; discussion 1843-4.
  • 47
    • 35148837581 scopus 로고    scopus 로고
    • Mechanisms of disease: Signaling of the insulin-like growth factor 1 receptor pathway - therapeutic perspectives in cancer
    • Tao Y, Pinzi V, Bourhis J, Deutsch E. (2007) Mechanisms of disease: signaling of the insulin-like growth factor 1 receptor pathway - therapeutic perspectives in cancer. Nat. Clin. Pract. Oncol. 4:591-602.
    • (2007) Nat. Clin. Pract. Oncol , vol.4 , pp. 591-602
    • Tao, Y.1    Pinzi, V.2    Bourhis, J.3    Deutsch, E.4
  • 48
    • 34848845313 scopus 로고    scopus 로고
    • Modifying IGF1 activity: An approach to treat endocrine disorders, atherosclerosis and cancer
    • Clemmons DR. (2007) Modifying IGF1 activity: an approach to treat endocrine disorders, atherosclerosis and cancer. Nat. Rev. Drug Discov. 6:821-33.
    • (2007) Nat. Rev. Drug Discov , vol.6 , pp. 821-833
    • Clemmons, D.R.1


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