Reduction of IKKα expression promotes chronic ultraviolet B exposure-induced skin inflammation and carcinogenesis

American Journal of Pathology

Volumn 176, Issue 5, 2010, Pages 2500-2508

  Xia, Xiaojun ^a   Park, Eunmi ^b   Liu, Bigang ^c   Willette Brown, Jami ^d   Gong, Wanghua ^e   Wang, Jiming ^d   Mitchell, David ^c   Fischer, Susan M ^c   Hu, Yinling ^d  

^a CENTER FOR CELL AND GENE THERAPY   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF TEXAS   (United States)

^d NATIONAL CANCER INSTITUTE   (United States)

^e SAIC FREDERICK INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

I KAPPA B KINASE ALPHA; INTERLEUKIN 1; INTERLEUKIN 6; MONOCYTE CHEMOTACTIC PROTEIN 1; PROTEIN P53; TUMOR NECROSIS FACTOR ALPHA; I KAPPA B KINASE; KI 67 ANTIGEN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CARCINOGENESIS; CELL MIGRATION; CONTROLLED STUDY; FEMALE; GENE MUTATION; KERATINOCYTE; LATENT PERIOD; MACROPHAGE; MITOGENESIS; MITOSIS RATE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RADIATION EXPOSURE; SKIN; SKIN INFLAMMATION; SKIN TUMOR; TUMOR VOLUME; ULTRAVIOLET B RADIATION; UPREGULATION; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CYTOLOGY; DNA REPAIR; GENE EXPRESSION REGULATION; GENETICS; INFLAMMATION; METABOLISM; MUTATION; PHYSIOLOGY; RADIOIMMUNOASSAY; TRANSGENIC MOUSE; TUMOR SUPPRESSOR GENE; ULTRAVIOLET RADIATION;

ANIMALS; CHEMOKINE CCL2; DNA REPAIR; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, P53; I-KAPPA B KINASE; INFLAMMATION; KERATINOCYTES; KI-67 ANTIGEN; MACROPHAGES; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MUTATION; RADIOIMMUNOASSAY; ULTRAVIOLET RAYS;

EID: 77952066545     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.2353/ajpath.2010.091041     Document Type: Article

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