Knock-in mutation of the distal four tyrosines of linker for activation of T cells blocks murine T cell development

Journal of Experimental Medicine

Volumn 194, Issue 2, 2001, Pages 135-142

  Sommers, Connie L ^a   Menon, Rashmi K ^a   Grinberg, Alexander ^b   Zhang, Weiguo ^c   Samelson, Lawrence E ^a   Love, Paul E ^b  

^a NATIONAL CANCER INSTITUTE   (United States)

^b EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^c DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Adapter; Development; Gene targeting; Signal transduction; Thymocyte

Indexed keywords

DOCKING PROTEIN; LINK PROTEIN; MUTANT PROTEIN; NUCLEAR FACTOR; PHENYLALANINE; T LYMPHOCYTE RECEPTOR; TYROSINE;

ANIMAL CELL; ARTICLE; CALCIUM MOBILIZATION; CELL MATURATION; CONTROLLED STUDY; GENE EXPRESSION; GENE MUTATION; GENE TARGETING; HUMAN; HUMAN CELL; KNOCKOUT MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; THYMOCYTE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; BASE SEQUENCE; CARRIER PROTEINS; CELL DIFFERENTIATION; DNA PRIMERS; LYMPHOCYTE ACTIVATION; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, MUTANT STRAINS; PHENOTYPE; PHOSPHOPROTEINS; PHOSPHORYLATION; RECEPTORS, ANTIGEN, T-CELL; SIGNAL TRANSDUCTION; T-LYMPHOCYTES; TYROSINE;

EID: 0035898379     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.194.2.135     Document Type: Article

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