STAT6 deletion converts the Th2 inflammatory pathology afflicting Lat Y136F mice into a lymphoproliferative disorder involving Th1 and CD8 effector T cells

Journal of Immunology

Volumn 182, Issue 5, 2009, Pages 2680-2689

  Archambaud, Cristel ^a,b,c   Sansoni, Amandine ^a,b,c   Mingueneau, Michael ^a,b,c   Devilard, Elisabeth ^a,b,c   Delsol, Georges ^b,d,e   Malissen, Bernard ^a,b,c   Malissen, Marie ^a,b,c  

^a CENTRE D IMMUNOLOGIE DE MARSEILLE LUMINY   (France)

^b INSERM   (France)

^c CNRS   (France)

^d UNIVERSITÉ DE TOULOUSE   (France)

^e CHU PURPAN   (France)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN G2A; IMMUNOGLOBULIN G2B; LAT PROTEIN; STAT6 PROTEIN; LAT PROTEIN, MOUSE; MEMBRANE PROTEIN; PHOSPHOPROTEIN; SIGNAL TRANSDUCING ADAPTOR PROTEIN; STAT6 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; B LYMPHOCYTE ACTIVATION; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL DIFFERENTIATION; CELL EXPANSION; CELL POPULATION; CELL PROLIFERATION; CONTROLLED STUDY; GENE DELETION; LYMPHOPROLIFERATIVE DISEASE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; TH1 CELL; TH2 CELL; AMINO ACID SUBSTITUTION; ANIMAL; C57BL MOUSE; COMPARATIVE STUDY; GENETICS; IMMUNOLOGY; INFLAMMATION; METABOLISM; MOUSE MUTANT; PATHOLOGY; PHYSIOLOGY;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AMINO ACID SUBSTITUTION; ANIMALS; CD8-POSITIVE T-LYMPHOCYTES; INFLAMMATION; LYMPHOPROLIFERATIVE DISORDERS; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, MUTANT STRAINS; PHOSPHOPROTEINS; STAT6 TRANSCRIPTION FACTOR; TH1 CELLS; TH2 CELLS;

EID: 64849091388     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0803257     Document Type: Article

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