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Volumn 15, Issue 5, 2010, Pages 463-472

Polymorphisms in SREBF1 and SREBF2, two antipsychotic-activated transcription factors controlling cellular lipogenesis, are associated with schizophrenia in German and Scandinavian samples

Author keywords

17p; 22q; Functional convergent genomics; Lipids; Myelin

Indexed keywords

GENOMIC DNA; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; STEROL REGULATORY ELEMENT BINDING PROTEIN 2;

EID: 77951878950     PISSN: 13594184     EISSN: 14765578     Source Type: Journal    
DOI: 10.1038/mp.2008.110     Document Type: Article
Times cited : (56)

References (63)
  • 1
    • 33747193538 scopus 로고    scopus 로고
    • Schizophrenia susceptibility genes converge on interlinked pathways related to glutamatergic transmission and long-term potentiation, oxidative stress and oligodendrocyte viability
    • Carter CJ. Schizophrenia susceptibility genes converge on interlinked pathways related to glutamatergic transmission and long-term potentiation, oxidative stress and oligodendrocyte viability. Schizophr Res 2006; 86: 1-14.
    • (2006) Schizophr Res , vol.86 , pp. 1-14
    • Carter, C.J.1
  • 3
    • 39449121270 scopus 로고    scopus 로고
    • The myelin-pathogenesis puzzle in schizophrenia: A literature review
    • DOI 10.1038/sj.mp.4002096, PII 4002096
    • Karoutzou G, Emrich HM, Dietrich DE. The myelin-pathogenesis puzzle in schizophrenia: a literature review. Mol Psychiatry 2008; 13: 245-260. (Pubitemid 351272657)
    • (2008) Molecular Psychiatry , vol.13 , Issue.3 , pp. 245-260
    • Karoutzou, G.1    Emrich, H.M.2    Dietrich, D.E.3
  • 6
    • 33750980390 scopus 로고    scopus 로고
    • Drug-induced activation of SREBP-controlled lipogenic gene expression in CNS-related cell lines: Marked differences between various antipsychotic drugs
    • DOI 10.1186/1471-2202-7-69
    • Ferno J, Skrede S, Vik-Mo AO, Ha?vik B, Steen VM. Drug-induced activation of SREBP-controlled lipogenic gene expression in CNS-related cell lines: marked differences between various antipsychotic drugs. BMC Neurosci 2006; 7: 69. (Pubitemid 44741152)
    • (2006) BMC Neuroscience , vol.7 , pp. 69
    • Ferno, J.1    Skrede, S.2    Vik-Mo, A.O.3    Havik, B.4    Steen, V.M.5
  • 8
    • 0032104180 scopus 로고    scopus 로고
    • Activation of cholesterol synthesis in preference to fatty acid synthesis in liver and adipose tissue of transgenic mice overproducing sterol regulatory element-binding protein-2
    • Horton JD, Shimomura I, Brown MS, Hammer RE, Goldstein JL, Shimano H. Activation of cholesterol synthesis in preference to fatty acid synthesis in liver and adipose tissue of transgenic mice overproducing sterol regulatory element-binding protein-2. J Clin Invest 1998; 101: 2331-2339. (Pubitemid 28270427)
    • (1998) Journal of Clinical Investigation , vol.101 , Issue.11 , pp. 2331-2339
    • Norton, J.D.1    Shimomura, I.2    Brown, M.S.3    Hammer, R.E.4    Goldstein, J.L.5    Shimano, H.6
  • 9
    • 38149026282 scopus 로고    scopus 로고
    • Compromised myelin integrity during psychosis with repair during remission in drug-responding schizophrenia
    • Garver DL, Holcomb JA, Christensen JD. Compromised myelin integrity during psychosis with repair during remission in drug-responding schizophrenia. Int J Neuropsychopharmacol 2008; 11: 49-61.
    • (2008) Int J Neuropsychopharmacol , vol.11 , pp. 49-61
    • Garver, D.L.1    Holcomb, J.A.2    Christensen, J.D.3
  • 10
    • 3543104951 scopus 로고    scopus 로고
    • Thematic review series: Brain lipids. Cholesterol metabolism in the central nervous system during early development and in the mature animal
    • Dietschy JM, Turley SD. Thematic review series: brain lipids. Cholesterol metabolism in the central nervous system during early development and in the mature animal. J Lipid Res 2004; 45: 1375-1397.
    • (2004) J Lipid Res , vol.45 , pp. 1375-1397
    • Dietschy, J.M.1    Turley, S.D.2
  • 11
    • 0030907175 scopus 로고    scopus 로고
    • Isoform 1c of sterol regulatory element binding protein is less active than isoform 1a in livers of transgenic mice and in cultured cells
    • Shimano H, Horton JD, Shimomura I, Hammer RE, Brown MS, Goldstein JL. Isoform 1c of sterol regulatory element binding protein is less active than isoform 1a in livers of transgenic mice and in cultured cells. J Clin Invest 1997; 99: 846-854. (Pubitemid 27123620)
    • (1997) Journal of Clinical Investigation , vol.99 , Issue.5 , pp. 846-854
    • Shimano, H.1    Horton, J.D.2    Shimomura, I.3    Hammer, R.E.4    Brown, M.S.5    Goldstein, J.L.6
  • 12
    • 0004235298 scopus 로고
    • American Psychiatric Association, Committee on Nomenclature and Statistics 4th edn. American Psychiatric Association: Washington
    • American Psychiatric Association, Committee on Nomenclature and Statistics. Diagnostic and statistical manual of mental disorders, 4th edn. American Psychiatric Association: Washington, 1994.
    • (1994) Diagnostic and Statistical Manual of Mental Disorders
  • 13
    • 0004085199 scopus 로고    scopus 로고
    • Structured Clinical Interview for DSM-IV Axis i Disorders
    • Patient ed New York State Psychiatric Institute: New York
    • First MB, Spitzer RL, Gibbon M, Williams JBW. Structured Clinical Interview for DSM-IV Axis I Disorders. Patient ed. Biometrics Research Department, New York State Psychiatric Institute: New York, 1997.
    • (1997) Biometrics Research Department
    • First, M.B.1    Spitzer, R.L.2    Gibbon, M.3    Williams, J.B.W.4
  • 14
    • 0026486965 scopus 로고
    • Methodological issues in using a polydiagnostic approach to define psychotic illness
    • Farmer AE, Wessely S, Castle D, McGuffin P. Methodological issues in using a polydiagnostic approach to define psychotic illness. Br J Psychiatry 1992; 161: 824-830.
    • (1992) Br J Psychiatry , vol.161 , pp. 824-830
    • Farmer, A.E.1    Wessely, S.2    Castle, D.3    McGuffin, P.4
  • 15
    • 0019951788 scopus 로고
    • Best estimate of lifetime psychiatric diagnosis. A methodological study
    • Leckman JF, Sholomskas D, Thompson WD, Belanger A, Weissman MM. Best estimate of lifetime psychiatric diagnosis: a methodological study. Arch Gen Psychiatry 1982; 39: 879-883. (Pubitemid 12042853)
    • (1982) Archives of General Psychiatry , vol.39 , Issue.8 , pp. 879-883
    • Leckman, J.F.1    Sholomskas, D.2    Thompson, W.D.3
  • 16
    • 0024284028 scopus 로고
    • A simple salting out procedure for extracting DNA from human nucleated cells
    • Miller SA, Dykes DD, Polesky HF. A simple salting out procedure for extracting DNA from human nucleated cells. Nucl Acids Res 1988; 16: 1215.
    • (1988) Nucl Acids Res , vol.16 , pp. 1215
    • Miller, S.A.1    Dykes, D.D.2    Polesky, H.F.3
  • 17
    • 13444269543 scopus 로고    scopus 로고
    • Haploview: Analysis and visualization of LD and haplotype maps
    • DOI 10.1093/bioinformatics/bth457
    • Barrett JC, Fry B, Maller J, Daly MJ. Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics 2005; 21: 263-265. (Pubitemid 40202029)
    • (2005) Bioinformatics , vol.21 , Issue.2 , pp. 263-265
    • Barrett, J.C.1    Fry, B.2    Maller, J.3    Daly, M.J.4
  • 25
    • 0042632779 scopus 로고    scopus 로고
    • Interaction between SREBP-1a and APOB polymorphisms influences total and low-density lipoprotein cholesterol levels in patients with coronary artery disease
    • Rios DL, Vargas AF, Torres MR, Zago AJ, Callegari-Jacques SM, Hutz MH. Interaction between SREBP-1a and APOB polymorphisms influences total and low-density lipoprotein cholesterol levels in patients with coronary artery disease. Clin Genet 2003; 63: 380-385.
    • (2003) Clin Genet , vol.63 , pp. 380-385
    • Rios, D.L.1    Vargas, A.F.2    Torres, M.R.3    Zago, A.J.4    Callegari-Jacques, S.M.5    Hutz, M.H.6
  • 26
    • 1842845028 scopus 로고    scopus 로고
    • Effects of SREBF-1a and SCAP polymorphisms on plasma levels of lipids, severity, progression and regression of coronary atherosclerosis and response to therapy with fluvastatin
    • Salek L, Lutucuta S, Ballantyne CM, Gotto Jr AM, Marian AJ. Effects of SREBF-1a and SCAP polymorphisms on plasma levels of lipids, severity, progression and regression of coronary atherosclerosis and response to therapy with fluvastatin. J Mol Med 2002; 80: 737-744.
    • (2002) J Mol Med , vol.80 , pp. 737-744
    • Salek, L.1    Lutucuta, S.2    Ballantyne, C.M.3    Gotto Jr, A.M.4    Marian, A.J.5
  • 27
    • 34548303945 scopus 로고    scopus 로고
    • Evidence for two schizophrenia susceptibility genes on chromosome 22q13
    • DOI 10.1097/YPG.0b013e3281ac2345, PII 0004144420071000000006
    • Condra JA, Neibergs H, Wei W, Brennan MD. Evidence for two schizophrenia susceptibility genes on chromosome 22q13. Psychiatry Genet 2007; 17: 292-298. (Pubitemid 47345751)
    • (2007) Psychiatric Genetics , vol.17 , Issue.5 , pp. 292-298
    • Condra, J.A.1    Neibergs, H.2    Wei, W.3    Brennan, M.D.4
  • 30
    • 1342300634 scopus 로고    scopus 로고
    • Oligodendroglial density in the prefrontal cortex in schizophrenia and mood disorders: A study from the Stanley neuropathology consortium
    • Uranova NA, Vostrikov VM, Orlovskaya DD, Rachmanova VI. Oligodendroglial density in the prefrontal cortex in schizophrenia and mood disorders: a study from the Stanley neuropathology consortium. Schizophr Res 2004; 67: 269-275.
    • (2004) Schizophr Res , vol.67 , pp. 269-275
    • Uranova, N.A.1    Vostrikov, V.M.2    Orlovskaya, D.D.3    Rachmanova, V.I.4
  • 36
    • 27744450725 scopus 로고    scopus 로고
    • Increase in gray matter and decrease in white matter volumes in the cortex during treatment with atypical neuroleptics in schizophrenia
    • DOI 10.1016/j.schres.2005.07.031, PII S0920996405002963
    • Molina V, Reig S, Sanz J, Palomo T, Benito C, Sánchez J et al. Increase in gray matter and decrease in white matter volumes in the cortex during treatment with atypical neuroleptics in schizophrenia. Schizophr Res 2005; 80: 61-71. (Pubitemid 41587464)
    • (2005) Schizophrenia Research , vol.80 , Issue.1 , pp. 61-71
    • Molina, V.1    Reig, S.2    Sanz, J.3    Palomo, T.4    Benito, C.5    Sanchez, J.6    Sarramea, F.7    Pascau, J.8    Desco, M.9
  • 39
    • 26844483219 scopus 로고    scopus 로고
    • Variations in myelin and oligodendrocyte-related gene expression across multiple brain regions in schizophrenia: A gene ontology study
    • DOI 10.1016/j.schres.2005.06.007, PII S0920996405002409
    • Katsel P, Davis KL, Haroutunian V. Variations in myelin and oligodendrocyte-related gene expression across multiple brain regions in schizophrenia: a gene ontology study. Schizophr Res 2005; 79: 157-173. (Pubitemid 41457256)
    • (2005) Schizophrenia Research , vol.79 , Issue.2-3 , pp. 157-173
    • Katsel, P.1    Davis, K.L.2    Haroutunian, V.3
  • 40
    • 4444324427 scopus 로고    scopus 로고
    • Microarray analysis of postmortem temporal cortex from patients with schizophrenia
    • DOI 10.1002/jnr.20208
    • Aston C, Jiang L, Sokolov BP. Microarray analysis of postmortem temporal cortex from patients with schizophrenia. J Neurosci Res 2004; 77: 858-866. (Pubitemid 39187068)
    • (2004) Journal of Neuroscience Research , vol.77 , Issue.6 , pp. 858-866
    • Aston, C.1    Jiang, L.2    Sokolov, B.P.3
  • 41
    • 15944367439 scopus 로고    scopus 로고
    • Transcriptional profiling reveals evidence for signaling and oligodendroglial abnormalities in the temporal cortex from patients with major depressive disorder
    • DOI 10.1038/sj.mp.4001565
    • Aston C, Jiang L, Sokolov BP. Transcriptional profiling reveals evidence for signaling and oligodendroglial abnormalities in the temporal cortex from patients with major depressive disorder. Mol Psychiatry 2005; 10: 309-322. (Pubitemid 40432684)
    • (2005) Molecular Psychiatry , vol.10 , Issue.3 , pp. 309-322
    • Aston, C.1    Jiang, L.2    Sokolov, B.P.3
  • 42
    • 33646067730 scopus 로고    scopus 로고
    • Ontogeny of the human central nervous system: What is happening when?
    • de Graaf-Peters VB, Hadders-Algra M. Ontogeny of the human central nervous system: what is happening when? Early Hum Dev 2006; 82: 257-266.
    • (2006) Early Hum Dev , vol.82 , pp. 257-266
    • De Graaf-Peters, V.B.1    Hadders-Algra, M.2
  • 46
    • 0036791990 scopus 로고    scopus 로고
    • Schizophrenia: Breakdown in the well-regulated lifelong process of brain development and maturation
    • Bartzokis G. Schizophrenia: breakdown in the well-regulated lifelong process of brain development and maturation. Neuro-psychopharmacology 2002; 27: 672-683.
    • (2002) Neuro-psychopharmacology , vol.27 , pp. 672-683
    • Bartzokis, G.1
  • 48
    • 0036251153 scopus 로고    scopus 로고
    • SREBPs: Activators of the complete program of cholesterol and fatty acid synthesis in the liver
    • Horton JD, Goldstein JL, Brown MS. SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver. J Clin Invest 2002; 109: 1125-1131.
    • (2002) J Clin Invest , vol.109 , pp. 1125-1131
    • Horton, J.D.1    Goldstein, J.L.2    Brown, M.S.3
  • 49
    • 0037137346 scopus 로고    scopus 로고
    • Cholesterol homeostasis: Not until the SCAP lady INSIGs
    • Loewen CJ, Levine TP. Cholesterol homeostasis: not until the SCAP lady INSIGs. Curr Biol 2002; 12: R779-R781.
    • (2002) Curr Biol , vol.12
    • Loewen, C.J.1    Levine, T.P.2
  • 51
    • 0141594942 scopus 로고    scopus 로고
    • Local regulation of fat metabolism in peripheral nerves
    • DOI 10.1101/gad.1116203
    • Verheijen MH, Chrast R, Burrola P, Lemke G. Local regulation of fat metabolism in peripheral nerves. Genes Dev 2003; 17: 2450-2464. (Pubitemid 37214792)
    • (2003) Genes and Development , vol.17 , Issue.19 , pp. 2450-2464
    • Verheijen, M.H.G.1    Chrast, R.2    Burrola, P.3    Lemke, G.4
  • 52
    • 34250827871 scopus 로고    scopus 로고
    • Oligodendroglial abnormalities in schizophrenia, mood disorders and substance abuse. Comorbidity, shared traits
    • Sokolov BP. Oligodendroglial abnormalities in schizophrenia, mood disorders and substance abuse. Comorbidity, shared traits, or molecular phenocopies? Int J Neuropsychopharmacol 2007; 10: 547-555.
    • (2007) Or Molecular Phenocopies? Int J Neuropsychopharmacol , vol.10 , pp. 547-555
    • Sokolov, B.P.1
  • 54
    • 45549101680 scopus 로고    scopus 로고
    • Quetiapine facilitates oligodendrocyte development and prevents mice from myelin breakdown and behavioral changes
    • DOI 10.1038/sj.mp.4002064, PII 4002064
    • Xiao L, Xu H, Zhang Y, Wei Z, He J, Jiang W et al. Quetiapine facilitates oligodendrocyte development and prevents mice from myelin breakdown and behavioral changes. Mol Psychiatry 2008; 13: 697-708. (Pubitemid 351861531)
    • (2008) Molecular Psychiatry , vol.13 , Issue.7 , pp. 697-708
    • Xiao, L.1    Xu, H.2    Zhang, Y.3    Wei, Z.4    He, J.5    Jiang, W.6    Li, X.7    Dyck, L.E.8    Devon, R.M.9    Deng, Y.10    Li, X.M.11
  • 56
    • 34247120097 scopus 로고    scopus 로고
    • Correlations between weight changes and lipid profile changes in schizophrenic patients after antipsychotics therapy
    • Huang TL, Lu CY. Correlations between weight changes and lipid profile changes in schizophrenic patients after antipsychotics therapy. Chang Gung Med J 2007; 30: 26-32.
    • (2007) Chang Gung Med J , vol.30 , pp. 26-32
    • Huang, T.L.1    Lu, C.Y.2
  • 58
    • 32244431947 scopus 로고    scopus 로고
    • Antidepressant drugs activate SREBP and up-regulate cholesterol and fatty acid biosynthesis in human glial cells
    • DOI 10.1016/j.neulet.2005.10.096, PII S0304394005012711
    • Raeder MB, Ferno J, Glambek M, Stansberg C, Steen VM. Antidepressant drugs activate SREBP and up-regulate cholesterol and fatty acid biosynthesis in human glial cells. Neurosci Lett 2006; 395: 185-190. (Pubitemid 43213141)
    • (2006) Neuroscience Letters , vol.395 , Issue.3 , pp. 185-190
    • Raeder, M.B.1    Ferno, J.2    Glambek, M.3    Stansberg, C.4    Steen, V.M.5
  • 59
    • 33748328048 scopus 로고    scopus 로고
    • SREBP activation by antipsychotic- and antidepressant-drugs in cultured human liver cells: Relevance for metabolic side-effects?
    • DOI 10.1007/s11010-006-9160-4
    • Raeder MB, Ferno J, Vik-Mo AO, Steen VM. SREBP activation by antipsychotic-and antidepressant-drugs in cultured human liver cells: relevance for metabolic side-effects? Mol Cell Biochem 2006; 289: 167-173. (Pubitemid 44322486)
    • (2006) Molecular and Cellular Biochemistry , vol.289 , Issue.1-2 , pp. 167-173
    • Raeder, M.B.1    Ferno, J.2    Vik-Mo, A.O.3    Steen, V.M.4
  • 61
    • 34547469943 scopus 로고    scopus 로고
    • Pharmacogenetics and pharmacogenomics of schizophrenia: A review of last decade of research
    • DOI 10.1038/sj.mp.4002009, PII 4002009
    • Arranz MJ, de Leon J. Pharmacogenetics and pharmacogenomics of schizophrenia: a review of last decade of research. Mol Psychiatry 2007; 12: 707-747. (Pubitemid 47172693)
    • (2007) Molecular Psychiatry , vol.12 , Issue.8 , pp. 707-747
    • Arranz, M.J.1    De Leon, J.2
  • 62
    • 60449089077 scopus 로고    scopus 로고
    • Association between the insulin-induced gene 2 (INSIG2) and weight gain in a German sample of antipsychotic-treated schizophrenic patients: Perturbation of SREBP-controlled lipogenesis in drug-related metabolic adverse effects?
    • e-pub ahead of print: doi:10.1038
    • Le Hellard S, Theisen FM, Haberhausen M, Raeder MB, Fernø J, Gebhardt S et al. Association between the insulin-induced gene 2 (INSIG2) and weight gain in a German sample of antipsychotic-treated schizophrenic patients: perturbation of SREBP-controlled lipogenesis in drug-related metabolic adverse effects?. Mol Psychiatry 2008; e-pub ahead of print: doi:10.1038.
    • (2008) Mol Psychiatry
    • Le Hellard, S.1    Theisen, F.M.2    Haberhausen, M.3    Raeder, M.B.4    Fernø, J.5    Gebhardt, S.6


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