Xenon inhibits excitatory but not inhibitory transmission in rat spinal cord dorsal horn neurons

Molecular Pain

Volumn 6, Issue , 2010, Pages

  Georgiev, Stefan K ^a   Furue, Hidemasa ^b,c   Baba, Hiroshi ^a   Kohno, Tatsuro ^a,d  

^a NIIGATA UNIVERSITY GRADUATE SCHOOL OF MEDICAL AND DENTAL SCIENCES   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

^c NATIONAL INSTITUTE FOR PHYSIOLOGICAL SCIENCES   (Japan)

^d Pain Mechanism Research Group   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; NEUROTRANSMITTER; XENON; 2 AMINO 5 PHOSPHOPENTANOIC ACID; 2-AMINO-5-PHOSPHOPENTANOIC ACID; DRUG DERIVATIVE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYLASPARTIC ACID; TETRODOTOXIN; VALINE;

ANALGESIC ACTIVITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFICACY; EVOKED SPINAL CORD RESPONSE; EXCITATORY POSTSYNAPTIC POTENTIAL; IN VITRO STUDY; IN VIVO STUDY; INHIBITORY POSTSYNAPTIC POTENTIAL; MALE; NOCICEPTION; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; RAT; SPINAL CORD DORSAL HORN; SPINAL CORD NERVE CELL; SYNAPTIC INHIBITION; SYNAPTIC TRANSMISSION; TACTILE STIMULATION; ANIMAL; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; METABOLISM; POSTERIOR HORN CELL; SPINAL CORD; WISTAR RAT;

ANIMALS; EXCITATORY POSTSYNAPTIC POTENTIALS; INHIBITORY POSTSYNAPTIC POTENTIALS; MALE; N-METHYLASPARTATE; PATCH-CLAMP TECHNIQUES; POSTERIOR HORN CELLS; RATS; RATS, WISTAR; RECEPTORS, N-METHYL-D-ASPARTATE; SPINAL CORD; TETRODOTOXIN; VALINE; XENON;

EID: 77951870346     PISSN: 17448069     EISSN: None     Source Type: Journal    
DOI: 10.1186/1744-8069-6-25     Document Type: Article

References (42)

1. Preckel B, Schlack W. Inert gases as the future inhalational anaesthetics?. Best Pract Res Clin Anaesthesiol 2005, 19:365-379. 10.1016/j.bpa.2005.01.002, 16013687.
2. Tonner PH, Bangert K, Scholz J. Xenon as a replacement for nitrous oxide?. Baillière's Best Practice and Research in Clinical Anaesthesiology 2001, 15:491-503.
3. Derwall M, Coburn M, Rex S, Hein M, Rossaint R, Fries M. Xenon: recent developments and future perspectives. Minerva Anestesiol 2009, 75:37-45.
4. Ma D, Wilhelm S, Maze M, Franks NP. Neuroprotective and neurotoxic properties of the 'inert' gas, xenon. Br J Anaesth 2002, 89:739-746. 10.1093/bja/aef258, 12393773.
5. David HN, Haelewyn B, Rouillon C, Lecoq M, Chazalviel L, Apiou G, Risso JJ, Lemaire M, Abraini JH. Neuroprotective effects of xenon: a therapeutic window of opportunity in rats subjected to transient cerebral ischemia. FASEB J 2008, 22:1275-1286. 10.1096/fj.07-9420com, 18024836.
6. Preckel B, Weber NC, Sanders RD, Maze M, Schlack W. Molecular mechanisms transducing the anesthetic, analgesic, and organ-protective actions of xenon. Anesthesiology 2006, 105:187-197. 10.1097/00000542-200607000-00029, 16810011.
7. Franks NP, Dickinson R, de Sousa SL, Hall AC, Lieb WR. How does xenon produce anaesthesia?. Nature 1998, 396:324. 10.1038/24525, 9845069.
8. Dickinson R, Peterson BK, Banks P, Simillis C, Martin JC, Valenzuela CA, Maze M, Franks NP. Competitive inhibition at the glycine site of the N-methyl-D-aspartate receptor by the anesthetics xenon and isoflurane: evidence from molecular modeling and electrophysiology. Anesthesiology 2007, 107:756-767. 10.1097/01.anes.0000287061.77674.71, 18073551.
9. de Sousa SL, Dickinson R, Lieb WR, Franks NP. Contrasting synaptic actions of the inhalational general anesthetics isoflurane and xenon. Anesthesiology 2000, 92:1055-1066. 10.1097/00000542-200004000-00024, 10754626.
10. Dinse A, Fohr KJ, Georgieff M, Beyer C, Bulling A, Weigt HU. Xenon reduces glutamate-, AMPA-, and kainate-induced membrane currents in cortical neurones. Br J Anaesth 2005, 94:479-485. 10.1093/bja/aei080, 15695547.
11. Haseneder R, Kratzer S, Kochs E, Eckle VS, Zieglgansberger W, Rammes G. Xenon reduces N-methyl-D-aspartate and alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor-mediated synaptic transmission in the amygdala. Anesthesiology 2008, 109:998-1006. 10.1097/ALN.0b013e31818d6aee, 19034096.
12. Utsumi J, Adachi T, Miyazaki Y, Kurata J, Shibata M, Murakawa M, Arai T, Mori K. The effect of xenon on spinal dorsal horn neurons: a comparison with nitrous oxide. Anesth Analg 1997, 84:1372-1376. 10.1097/00000539-199706000-00036, 9174323.
13. Miyazaki Y, Adachi T, Utsumi J, Shichino T, Segawa H. Xenon has greater inhibitory effects on spinal dorsal horn neurons than nitrous oxide in spinal cord transected cats. Anesth Analg 1999, 88:893-897. 10.1097/00000539-199904000-00038, 10195543.
14. David HN, Leveille F, Chazalviel L, MacKenzie ET, Buisson A, Lemaire M, Abraini JH. Reduction of ischemic brain damage by nitrous oxide and xenon. J Cereb Blood Flow Metab 2003, 23:1168-1173. 10.1097/01.WCB.0000087342.31689.18, 14526227.
15. Koblin DD, Fang Z, Eger EI, Laster MJ, Gong D, Ionescu P, Halsey MJ, Trudell JR. Minimum alveolar concentrations of noble gases, nitrogen, and sulfur hexafluoride in rats: helium and neon as nonimmobilizers (nonanesthetics). Anesth Analg 1998, 87:419-424. 10.1097/00000539-199808000-00035, 9706943.
16. Yagi M, Mashimo T, Kawaguchi T, Yoshiya I. Analgesic and hypnotic effects of subanaesthetic concentrations of xenon in human volunteers: comparison with nitrous oxide. Br J Anaesth 1995, 74:670-673. 10.1093/bja/74.6.670, 7640122.
17. Petersen-Felix S, Luginbuhl M, Schnider TW, Curatolo M, Arendt-Nielsen L, Zbinden AM. Comparison of the analgesic potency of xenon and nitrous oxide in humans evaluated by experimental pain. Br J Anaesth 1998, 81:742-747.
18. Watanabe I, Takenoshita M, Sawada T, Uchida I, Mashimo T. Xenon suppresses nociceptive reflex in newborn rat spinal cord in vitro; comparison with nitrous oxide. Eur J Pharmacol 2004, 496:71-76. 10.1016/j.ejphar.2004.06.005, 15288577.
19. Yamakura T, Harris RA. Effects of gaseous anesthetics nitrous oxide and xenon on ligand-gated ion channels. Comparison with isoflurane and ethanol. Anesthesiology 2000, 93:1095-1101. 10.1097/00000542-200010000-00034, 11020766.
20. Benrath J, Kempf C, Georgieff M, Sandkuhler J. Xenon blocks the induction of synaptic long-term potentiation in pain pathways in the rat spinal cord in vivo. Anesth Analg 2007, 104:106-111. 10.1213/01.ane.0000250368.27822.31, 17179253.
21. Adolph O, Koster S, Georgieff M, Bader S, Fohr KJ, Kammer T, Herrnberger B, Gron G. Xenon-induced changes in CNS sensitization to pain. Neuroimage 2010, 49:720-730. 10.1016/j.neuroimage.2009.08.034, 19703572.
22. Wilhelm S, Ma D, Maze M, Franks NP. Effects of xenon on in vitro and in vivo models of neuronal injury. Anesthesiology 2002, 96:1485-1491. 10.1097/00000542-200206000-00031, 12170064.
23. Nishiyama T, Yaksh TL, Weber E. Effects of intrathecal NMDA and non-NMDA antagonists on acute thermal nociception and their interaction with morphine. Anesthesiology 1998, 89:715-722. 10.1097/00000542-199809000-00023, 9743410.
24. Dougherty PM, Palecek J, Paleckova V, Sorkin LS, Willis WD. The role of NMDA and non-NMDA excitatory amino acid receptors in the excitation of primate spinothalamic tract neurons by mechanical, chemical, thermal, and electrical stimuli. J Neurosci 1992, 12:3025-3041.
25. Hang L, Shao D, Yang Y, Sun W, Dai T, Zeng Y. Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors participate in the analgesic but not hypnotic effects of emulsified halogenated anaesthetics. Basic Clin Pharmacol Toxicol 2008, 103:31-35. 10.1111/j.1742-7843.2008.00270.x, 18598297.
26. Haseneder R, Kurz J, Dodt HU, Kochs E, Zieglgansberger W, Scheller M, Rammes G, Hapfelmeier G. Isoflurane reduces glutamatergic transmission in neurons in the spinal cord superficial dorsal horn: evidence for a presynaptic site of an analgesic action. Anesth Analg 2004, 98:1718-1723. 10.1213/01.ANE.0000112309.80017.3F, 15155334.
27. Garry EM, Fleetwood-Walker SM. A new view on how AMPA receptors and their interacting proteins mediate neuropathic pain. Pain 2004, 109:210-213. 10.1016/j.pain.2004.04.002, 15157680.
28. Bleakman D, Alt A, Nisenbaum ES. Glutamate receptors and pain. Semin Cell Dev Biol 2006, 17:592-604. 10.1016/j.semcdb.2006.10.008, 17110139.
29. Plested AJ, Wildman SS, Lieb WR, Franks NP. Determinants of the sensitivity of AMPA receptors to xenon. Anesthesiology 2004, 100:347-358. 10.1097/00000542-200402000-00025, 14739810.
30. Nagy GG, Al-Ayyan M, Andrew D, Fukaya M, Watanabe M, Todd AJ. Widespread expression of the AMPA receptor GluR2 subunit at glutamatergic synapses in the rat spinal cord and phosphorylation of GluR1 in response to noxious stimulation revealed with an antigen-unmasking method. J Neurosci 2004, 24:5766-5777. 10.1523/JNEUROSCI.1237-04.2004, 15215299.
31. Millan MJ. The induction of pain: an integrative review. Prog Neurobiol 1999, 57:1-164. 10.1016/S0301-0082(98)00048-3, 9987804.
32. Nagele P, Metz LB, Crowder CM. Xenon acts by inhibition of non-N-methyl-D-aspartate receptor-mediated glutamatergic neurotransmission in Caenorhabditis elegans. Anesthesiology 2005, 103:508-513. 10.1097/00000542-200509000-00013, 16129975.
33. Haseneder R, Kratzer S, Kochs E, Mattusch C, Eder M, Rammes G. Xenon attenuates excitatory synaptic transmission in the rodent prefrontal cortex and spinal cord dorsal horn. Anesthesiology 2009, 111:1297-1307. 10.1097/ALN.0b013e3181c14c05, 19934875.
34. Hara K, Harris RA. The anesthetic mechanism of urethane: the effects on neurotransmitter-gated ion channels. Anesth Analg 2002, 94:313-318. 10.1097/00000539-200202000-00015, 11812690.
35. Takazawa T, Furue H, Nishikawa K, Uta D, Takeshima K, Goto F, Yoshimura M. Actions of propofol on substantia gelatinosa neurones in rat spinal cord revealed by in vitro and in vivo patch-clamp recordings. Eur J Neurosci 2009, 29:518-528. 10.1111/j.1460-9568.2008.06607.x, 19222560.
36. Hapfelmeier G, Zieglgansberger W, Haseneder R, Schneck H, Kochs E. Nitrous oxide and xenon increase the efficacy of GABA at recombinant mammalian GABA(A) receptors. Anesth Analg 2000, 91:1542-1549. 10.1097/00000539-200012000-00045, 11094015.
37. Salmi E, Laitio RM, Aalto S, Maksimow AT, Langsjo JW, Kaisti KK, Aantaa R, Oikonen V, Metsahonkala L, Nagren K, et al. Xenon does not affect gamma-aminobutyric acid type A receptor binding in humans. Anesth Analg 2008, 106:129-134. 10.1213/01.ane.0000287658.14763.13, 18165567.
38. Georgiev SK, Kohno T, Ikoma M, Yamakura T, Baba H. Nitrous oxide inhibits glutamatergic transmission in spinal dorsal horn neurons. Pain 2008, 134:24-31. 10.1016/j.pain.2007.03.026, 17481820.
39. Georgiev SK, Baba H, Kohno T. Nitrous oxide and the inhibitory synaptic transmission in rat dorsal horn neurons. Eur J Pain 2010, 14:17-22. 10.1016/j.ejpain.2009.01.008, 19261495.
40. Kohno T, Kumamoto E, Baba H, Ataka T, Okamoto M, Shimoji K, Yoshimura M. Actions of midazolam on GABAergic transmission in substantia gelatinosa neurons of adult rat spinal cord slices. Anesthesiology 2000, 92:507-515. 10.1097/00000542-200002000-00034, 10691239.
41. Furue H, Narikawa K, Kumamoto E, Yoshimura M. Responsiveness of rat substantia gelatinosa neurones to mechanical but not thermal stimuli revealed by in vivo patch-clamp recording. J Physiol 1999, 521:529-535. 10.1111/j.1469-7793.1999.00529.x, 2269671, 10581321.
42. Furue H, Kato G, Kim JH, Min B-I, Katafuchi T, Yoshimura M. In vivo patch-clamp analysis of sensory neuronal circuit in the rat superficial spinal dorsal horn. International Congress Series 2004, 1269:69-72.