Xenon has greater inhibitory effects on spinal dorsal horn neurons than nitrous oxide in spinal cord transected cats

Anesthesia and Analgesia

Volumn 88, Issue 4, 1999, Pages 893-897

  Miyazaki, Yoshiya ^a   Adachi, Takehiko ^a   Utsumi, Jun ^a   Shichino, Tsutomu ^a   Segawa, Hajime ^a  

^a KYOTO UNIVERSITY HOSPITAL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ATROPINE; CHLORALOSE; KETAMINE; NITROUS OXIDE; URETHAN; VECURONIUM; XENON;

ANIMAL EXPERIMENT; ANTINOCICEPTION; ARTICLE; CAT; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFECT; DRUG MECHANISM; FEMALE; INHALATION ANESTHESIA; INTRAMUSCULAR DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; MALE; NERVE POTENTIAL; NONHUMAN; PRIORITY JOURNAL; SPINAL CORD DORSAL HORN; SPINAL CORD NERVE CELL; SPINAL CORD TRANSSECTION; TACTILE STIMULATION;

EID: 0032943007     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1213/00000539-199904000-00038     Document Type: Article

References (24)

1. Kennedy RR, Stokes JW, Downing P. Anaesthesia and the 'inert' gases with special reference to xenon. Anaesth Intensive Care 1992;20:66-70.
2. Lane GA, Nahrwold ML, Tait AR, et al. Anesthetics as teratogens: nitrous oxide is fetotoxic, xenon is not. Science 1980; 210:899-901.
3. Cullen SC, Eger EI, Cullen BF, Gregory P. Observations on the anesthetic effect of the combination of xenon and halothane. Anesthesiology 1969;31:305-9.
4. Lachmann B, Armbruster S, Schairer W, et al. Safety and efficacy of xenon in routine use as an inhalational anaesthetic. Lancet 1990;335:1413-5.
5. Steward A, Allott PR, Cowles AL, Mapleson WW. Solubility coefficients for inhaled anaesthetics for water, oil and biological media. Br J Anaesth 1973;45:282-93.
6. Luttropp HH, Rydgren G, Thomasson R, Werner O. A minimal-flow system for xenon anesthesia. Anesthesiology 1991;75: 896-902.
7. Saito H, Saito M, Goto T, Morita S. Priming of anesthesia circuit with xenon for closed circuit anesthesia. Artif Organs 1997;21: 70-2.
8. Utsumi J, Adachi T, Miyazaki Y, et al. The effect of xenon on spinal dorsal horn neurons: a comparison with nitrous oxide. Anesth Analg 1997;84:1372-6.
9. Komatsu T, Shingu K, Tomemori N, et al. Nitrous oxide activates the supraspinal pain inhibition system. Acta Anaesthesiol Scand 1981;25:519-22.
10. Guo TZ, Poree L, Golden W, et al. Antinociceptive response to nitrous oxide is mediated by supraspinal opiate and spinal alpha 2 adrenergic receptors in the rat. Anesthesiology 1996;85: 846-52.
11. Herbert D, Mitcell R. Blood gas tensions and acid-base balance in awake cat. J Appl Physiol 1971;30:434-6.
12. Rexed B. A cytoarchitectonic atlas of the spinal cord in the cat. J Comp Neurol 1954;100:297-379.
13. Ohara A, Mashimo T, Zhang P, et al. A comparative study of the antinociceptive action of xenon and nitrous oxide in rats. Anesth Analg 1997;85:931-6.
14. Yagi M, Mashimo T, Kawaguchi T, Yoshiya I. Analgesic and hypnotic effects of subanaesthetic concentrations of xenon in human volunteers: comparison with nitrous oxide. Br J Anaesth 1995;74:670-3.
15. Utsumi J, Adachi T, Kurata J, et al. The effects of xenon on central nervous system electrical activity during sevoflurane anaesthesia in cats; a comparison with nitrous oxide. Br J Anaesth 1998;80:628-33.
16. Berkowitz BA, Finck AD, Ngai SH. Nitrous oxide analgesia: reversal by naloxone and development of tolerance. J Pharmacol Exp Ther 1977;203:539-47.
17. Gillman MA. Nitrous oxide, an opioid addictive agent: review of the evidence. Am J Med 1986;81:97-102.
18. Quock RM, Graczak LM. Influence of narcotic antagonist drugs upon nitrous oxide analgesia in mice. Brain Res 1988;440:35-41.
19. Smith RA, Wilson M, Miller KW. Naloxone has no effect on nitrous oxide anesthesia. Anesthesiology 1978;49:6-8.
20. Shingu K, Osawa M, Omatsu Y, et al. Naloxone does not antagonize the anesthetic-induced depression of nociceptor-driven spinal cord response in spinal cats. Acta Anaesthesiol Scand 1981;25:526-32.
21. Adachi T, Miyazaki Y, Kurata J, et al. Nitrous oxide depresses somatocardiac sympathetic A-and C-reflexes in anesthetized rats. Neurosci Lett 1996;213:57-60.
22. Fang F, Guo TZ, Davies MF, Maze M. Opiate receptors in the periaqueductal gray mediate analgesic effect of nitrous oxide in rats. Eur J Pharmacol 1997-336:137-41.
23. Jong RH, Robles R, Morikawa KI. Actions of halothane and nitrous oxide on dorsal horn neurons ("The Spinal Gate"). Anesthesiology 1969;31:205-12.
24. Kitahata LM, Taub A, Sato I. Lamina-specific suppression of dorsal horn unit activity by nitrous oxide and by hyperventilation. J Pharmacol Exp Ther 1971;176:101-8.