Xenon does not affect γ-aminobutyric acid type A receptor binding in humans

Anesthesia and Analgesia

Volumn 106, Issue 1, 2008, Pages 129-134

  Salmi, Elina ^a,d   Laitio, Ruut M ^d   Aalto, Sargo ^a,c   Maksimow, Anu T ^a   Långsjö, Jaakko W ^a,d   Kaisti, Kaike K ^d   Aantaa, Riku ^d   Oikonen, Vesa ^a   Metsähonkala, Liisa ^e   Någren, Kjell ^a   Korpi, Esa R ^f   Scheinin, Harry ^a,b  

^a TURKU PET CENTRE   (Finland)

^b UNIVERSITY OF TURKU   (Finland)

^c ÅBO AKADEMI UNIVERSITY   (Finland)

^d TURKU UNIVERSITY HOSPITAL   (Finland)

^e HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^f UNIVERSITY OF HELSINKI   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; CARBON 13; FLUMAZENIL; XENON;

ADULT; ARTICLE; AUTOANALYSIS; BISPECTRAL INDEX; BRAIN CORTEX; BRAIN REGION; DRUG BINDING; GRAY MATTER; HEART RATE; HUMAN; HUMAN EXPERIMENT; INHALATION ANESTHESIA; LUNG ALVEOLUS; MALE; MEAN ARTERIAL PRESSURE; NORMAL HUMAN; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; RECEPTOR BINDING;

ADULT; ANESTHETICS; BRAIN; CARBON RADIOISOTOPES; ELECTROENCEPHALOGRAPHY; FLUMAZENIL; GABA MODULATORS; HEMODYNAMICS; HUMANS; LIGANDS; MALE; POSITRON-EMISSION TOMOGRAPHY; PROTEIN BINDING; RADIOPHARMACEUTICALS; RECEPTORS, GABA-A; XENON;

EID: 37549031730     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1213/01.ane.0000287658.14763.13     Document Type: Article

References (38)

1. Cullen SC, Gross EG. The anesthetic properties of xenon in animals and human beings, with additional observations on krypton. Science 1951;113:580-2
2. Wilhelm S, Ma D, Maze M, Franks NP. Effects of xenon in vitro and in vivo models of neuronal injury. Anesthesiology 2002;96:1485-91
3. Schmidt M, Marx T, Göggl E, Reinelt H, Schirmer U. Xenon attenuates cerebral damage after ischemia in pigs. Anesthesiology 2005;102:929-36
4. Goto T, Hanne P, Ishiguro Y, Ichninose F, Niimi Y, Morita S. Cardiovascular effects of xenon and nitrous oxide in patients during fentanyl-midazolam anesthesia. Anesthesia 2004;59:1178-83
5. Coburn M, Kunitz O, Baumert JH, Hecker K, Haaf S, Zuhlsdorff A, Beeker T, Rossaint R. Randomized controlled trial of hemodynamic and recovery effects of xenon or propofol anesthesia. Br J Anaesth 2005;94:198-202
6. Franks NP, Dickinson R, de Sousa SLM, Hall AC, Lieb WR. How does xenon produce anesthesia? Nature 1998;396:324
7. Thompson SA and Wafford K. Mechanism of action of general anesthetics-new information from molecular pharmacology. Curr Opin Pharmacol 2001;1:78-83
8. A receptors. Anesth Analg 2000;91:1542-9
9. Yamakura T, Harris RA. Effects of gaseous anesthetics nitrous oxide and xenon on ligand-gated ion channels: comparison with isoflurane and ethanol. Anesthesiology 2000;93:1095-101
10. A benzodiazepine receptor binding by isoflurane. Anesthesiology 2001;95:585-93
11. 11C-flumazenil binding to gamma-aminobutyric acidA receptors in humans. Anesth Analg 2004;99:1420-26
12. 11C-flumazenil binding in humans. Anesth Analg 2005;101:722-5
13. Långsjö JW, Kaisti KK, Aalto S, Hinkka S, Aantaa R, Oikonen V, Sipilä H, Kurki T, Silvanto M, Scheinin H. Effects of subanesthetic doses of ketamine on regional cerebral blood flow, oxygen consumption, and blood volume in humans. Anesthesiology 2003;99:614-23
14. Långsjö JW, Salmi E, Kaisti KK, Aalto S, Hinkka S, Aantaa R, Oikonen V, Viljanen T, Kurki T, Silvanto M, Scheinin H. Effects of subanesthetic ketamine on regional cerebral glucose metabolism in humans. Anesthesiology 2004;100:1065-71
15. Rex S, Schaefer W, Meyer PH, Roissaint R, Boy C, Setani K, Büll U, Baumert JH. Positron emission tomography study of regional cerebral metabolism during general anesthesia with xenon in humans. Anesthesiology 2006;105:936-43
16. 2O enhances ketamine-induced c-Fos expression in rat posterior cingulate and retrospinal cortices. Anesth Analg 2001;92:362-8
17. Sakamoto S, Nakao S, Masuzawa M, Inada T, Maze M, Franks NP, Shingu K. The differential effects of nitrous oxide and xenon on extracellular dopamine levels in the rat nucleus accumbens: a microdialysis study. Anesth Analg 2006;103:1459-63
18. Laitio RM, Kaisti KK, Långsjö JW, Aalto S, Salmi E, Maksimow A, Aantaa R, Oikonen V, Sipilä H, Parkkola R, Scheinin H. Effects of xenon anesthesia on cerebral blood flow in humans: a positron emission tomography study. Anesthesiology 2007;106:1128-33
19. Nakata Y, Goto T, Ischiguro Y, Terui K, Kawakami H, Santo M, Niimi Y, Morita S. Minimum alveolar concentration (MAC) of xenon with sevoflurane in humans. Anesthesiology 2001;94:611-4
20. 11C]methionine. J Labeled Compd Rad 1998;41:831-41
21. Friston KJ, Holmes AP, Worsley KJ, Poline JP, Frith CD, Frackowiak RSJ. Statistical parametric maps in functional imaging: a general linear approach. Hum Brain Mapp 1995;2:189-210
22. Ashburner J, Friston K. Multimodal image coregistration and partitioning-a unified framework. Neuroimage 1997;6:209-17
23. Ashburner J, Friston KJ. Nonlinear spatial normalization using basis functions. Hum Brain Mapp 1999;7:254-66
24. 18F]fluoro-L-dopa uptake and frontal cognitive functions in early Parkinson's disease. Neurobiol Aging 2005;26:891-8
25. 11C]PIB uptake in Alzheimer disease. Neurology 2006;67:1575-80
26. De Sousa SLM, Dickinson R, Lieb WR, Franks NP. Contrasting synaptic actions of the inhalational general anesthetics isoflurane and xenon. Anesthesiology 2000;92:1055-66
27. Alkire MT, Haier RJ. Correlating in vivo anesthetic effects with ex vivo receptor density data supports a GABAergic mechanism of action for propofol, but not for isoflurane. Br J Anaesth 2001;86:618-26
28. Friederich P, Dybek A, Urban BW. Sterospecific interaction of ketamine with nicotinic acetylcholine receptors in human sympathetic ganglion-like SH-SY5Y cells. Anesthesiology 2000;93:818-24
29. Hirota K, Okawa H, Appadu BL, Grandy DK, Devi LA, Lambert DG. Stereoselective interaction of ketamine with recombinant μ, κ, and δ- opioid receptors expressed in Chinese hamster ovary cells. Anesthesiology 1999;90:174-82
30. Tso MM, Blatchford KL, Callado LF, McLauhghlin DP, Stamford JA. Stereoselective effects of ketamine on dopamine, serotonin and noradrenaline release and uptake in rat brain slices. Neurochem Int 2004;44:1-7
31. Möhler H, Richards JG. Agonist and antagonist benzodiazepine receptor interaction in vitro. Nature 1981;294:763-5
32. Hunkeler W, Möhler H, Pieri L, Polc C, Bonetti EP, Cumin R, Schaffner R, Haefely W. Selective antagonists of benzodiazepines. Nature 1981;290:514-6
33. Slifstein M, Laruelle M. Models and methods for derivation of in vivo neuroreceptor parameters with PET and SPECT reversible radiotracers. Nucl Med Biol 2001;28:595-608
34. Korpi ER, Gründer G, Lüddens H. Drug interactions at GABAA receptors. Prog Neurobiol 2002;67:113-59
35. Nagele P, Metz LB, Crowder CM. Xenon acts by inhibition of non-N-methyl-D-aspartate receptor-mediated glutamatergic neurotransmission in Caenorhabditis elegans. Anesthesiology 2005;103:508-13
36. Daniels S, Roberts RJ. Post-synaptic inhibitory mechanisms of anesthesia: glycine receptors. Toxicol Lett 1998;100-101:71-6
37. + channels are a novel target for anesthetic gases xenon, nitrous oxide, and cyclopropane. Mol Pharmacol 2004;65:443-52
38. Preckel B, Weber NC, Sanders RD, Maze M, Schlack W. Molecular mechanisms transducing the anesthetic, analgesic, and organ-protective actions of xenon. Anesthesiology 2006;105:187-97