Downregulation of adipose glutathione S-tansferase A4 leads to increased protein carbonylation, oxidative stress, and mitochondrial dysfunction

Diabetes

Volumn 59, Issue 5, 2010, Pages 1132-1142

  Curtis, Jessica M ^a   Grimsrud, Paul A ^a   Wright, Wendy S ^a   Xu, Xin ^b   Foncea, Rocio E ^a   Graham, David W ^a   Brestoff, Jonathan R ^a   Wiczer, Brian M ^a   Ilkayeva, Olga ^c   Cianflone, Katherine ^d   Muoio, Deborah E ^c,e   Arriaga, Edgar A ^b   Bernlohr, David A ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

^b University of Minnesota   (United States)

^c DUKE UNIVERSITY   (United States)

^d MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

^e DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COPPER ZINC SUPEROXIDE DISMUTASE; GLUCOSE TRANSPORTER; GLUTATHIONE PEROXIDASE 1; GLUTATHIONE TRANSFERASE A4; HEME OXYGENASE 1; MESSENGER RNA; PROTEIN; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SUPEROXIDE;

ADIPOCYTE; ADIPOSE TISSUE; ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ARTICLE; CARBONYLATION; CELL STRAIN 3T3; CONTROLLED STUDY; DOWN REGULATION; FEMALE; GENE EXPRESSION; GENE SILENCING; GLUCOSE METABOLISM; GLUCOSE TRANSPORT; INSULIN RESISTANCE; LIPOLYSIS; MALE; MICROARRAY ANALYSIS; MITOCHONDRIAL RESPIRATION; MITOCHONDRION; MOUSE; NONHUMAN; OBESITY; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; WILD TYPE;

3T3-L1 CELLS; ANIMALS; DOWN-REGULATION; GLUTATHIONE TRANSFERASE; HUMANS; INSULIN RESISTANCE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MITOCHONDRIA; OBESITY; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OXIDATIVE STRESS; PROTEIN CARBONYLATION;

EID: 77951842594     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db09-1105     Document Type: Article

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