Calcium sensitivity, force frequency relationship and cardiac troponin I: Critical role of PKA and PKC phosphorylation sites

Journal of Molecular and Cellular Cardiology

Volumn 48, Issue 5, 2010, Pages 943-953

  Ramirez Correa, Genaro A ^a   Cortassa, Sonia ^a   Stanley, Brian ^a   Gao, Wei Dong ^a   Murphy, Anne M ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Computational modeling; CTnI phosphorylation; E C coupling; Force frequency relation; Isolated trabeculae; Myofilament Ca2+ sensitivity; Protein kinase A; Protein kinase C

Indexed keywords

CALCIUM; CYCLIC AMP DEPENDENT PROTEIN KINASE; PROTEIN KINASE C; TROPONIN C; TROPONIN I;

ANIMAL TISSUE; ARTICLE; CALCIUM SIGNALING; CONTROLLED STUDY; ENZYME ACTIVATION; FEMALE; HEART CONTRACTION; HEART FAILURE; HEART MUSCLE RELAXATION; HYSTERESIS; INOTROPISM; MALE; MATHEMATICAL MODEL; MOUSE; MUSCLE FORCE; MUSCLE TWITCH; MYOFILAMENT; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TISSUE LEVEL; TRANSGENIC MOUSE;

ANIMALS; CALCIUM; COMPUTER SIMULATION; CYCLIC AMP-DEPENDENT PROTEIN KINASES; FEMALE; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MICROFILAMENTS; MYOCARDIUM; PHOSPHORYLATION; PROTEIN KINASE C; TROPONIN I;

MUS; MUS MUSCULUS;

EID: 77951621403     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2010.01.004     Document Type: Article

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