Frequency-dependent myofilament Ca2+ desensitization in failing rat myocardium

Journal of Physiology

Volumn 582, Issue 2, 2007, Pages 695-709

  Lamberts, Regis R ^a   Hamdani, Nazha ^b   Soekhoe, Tenoedj W ^b   Boontje, Nicky M ^b   Zaremba, Ruud ^b   Walker, Lori A ^c   De Tombe, Pieter P ^d   Van Der Velden, Jolanda ^b   Stienen, Ger J M ^b  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^b VU UNIVERSITY AMSTERDAM   (Netherlands)

^c UNIVERSITY OF COLORADO   (United States)

^d UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; CONTRACTILE PROTEIN; CYCLIC AMP DEPENDENT PROTEIN KINASE; MONOCROTALINE; MYOSIN LIGHT CHAIN; TROPONIN I; CALCIUM; MYOSIN LIGHT CHAIN 2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL ISOLATION; CHEMOSENSITIVITY; CONTROLLED STUDY; HEART FAILURE; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILE FORCE; HEART RATE; MALE; MYOFILAMENT; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; CALCIUM BLOOD LEVEL; CONGESTIVE HEART FAILURE; DESENSITIZATION; FREQUENCY DEPENDENT SELECTION; HEART LEFT VENTRICLE FAILURE; HEART MUSCLE; HEART PERFORMANCE; INCUBATION TIME; PROTEIN ANALYSIS; PROTEIN EXPRESSION;

ANIMALS; CALCIUM; CARDIAC OUTPUT, LOW; CONTRACTILE PROTEINS; HEART; HEART VENTRICLES; INTRACELLULAR MEMBRANES; MALE; MICROFILAMENTS; MONOCROTALINE; MYOCARDIAL CONTRACTION; MYOCARDIUM; MYOCYTES, CARDIAC; MYOSIN LIGHT CHAINS; PHOSPHORYLATION; PRESSURE; PROTEIN KINASE C-ALPHA; RATS; RATS, WISTAR; TROPONIN I;

EID: 34447264488     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2007.134486     Document Type: Article

References (57)

1. i transients in mouse ventricular myocytes. J Physiol 543, 889-898.
2. 2+ transport. Circ Res 93, 487-490.
3. Bilchick KC, Duncan JG, Ravi R, Takimoto E, Champion HC, Gao WD, Stull LB, Kass DA & Murphy AM (2007). Heart failure-associated alterations in troponin I phosphorylation impair ventricular relaxation-afterload and force-frequency responses and systolic function. Am J Physiol Heart Circ Physiol 292, H318-H325.
4. Bodor GS, Oakeley AE, Allen PD, Crimmins DL, Ladenson JH & Anderson PA (1997). Troponin I phosphorylation in the normal and failing adult human heart. Circulation 96, 1495-1500.
5. 2+-sensitive isoforms in the failing human heart. Circulation 99, 384-391.
6. Braz JC, Gregory K, Pathak A, Zhao W, Sahin B, Klevitsky R et al. (2004). PKC-α regulates cardiac contractility and propensity toward heart failure. Nat Med 10, 248-254.
7. 2+ sensitizer levosimendan in human myocardium. Am J Physiol Heart Circ Physiol 282, H131-H137.
8. Buermans HP, Redout EM, Schiel AE, Musters RJ, Zuidwijk M, Eijk PP, van Hardeveld C, Kasanmoentalib S, Visser FC, Ylstra B & Simonides WS (2005). Microarray analysis reveals pivotal divergent mRNA expression profiles early in the development of either compensated ventricular hypertrophy or heart failure. Physiol Genomics 21, 314-323.
9. DeSantiago J, Maier LS & Bers DM (2002). Frequency-dependent acceleration of relaxation in the heart depends on CaMKII, but not phospholamban. J Mol Cell Cardiol 34, 975-984.
10. Dias FA, Walker LA, Arteaga GM, Walker JS, Vijayan K, Pena JR, Ke Y, Fogaca RT, Sanbe A, Robbins J & Wolska BM (2006). The effect of myosin regulatory light chain phosphorylation on the frequency-dependent regulation of cardiac function. J Mol Cell Cardiol 41, 330-339.
11. Eising GP, Hammond HK, Helmer GA, Gilpin E & Ross J Jr (1994). Force-frequency relations during heart failure in pigs. Am J Physiol Heart Circ Physiol 267, H2516-H2522.
12. Fitzsimons DP, Bodell PW & Baldwin KM (1989). Phosphorylation of rodent cardiac myosin light chain 2: Effects of exercise. J Appl Physiol 67, 2447-2453.
13. Gao WD, Perez NG & Marban E (1998). Calcium cycling and contractile activation in intact mouse cardiac muscle. J Physiol 507, 175-184.
14. Garvey JL, Kranias EG & Solaro RJ (1988). Phosphorylation of C-protein, troponin I and phospholamban in isolated rabbit hearts. Biochem J 249, 709-714.
15. Gwathmey JK, Slawsky MT, Hajjar RJ, Briggs GM & Morgan JP (1990). Role of intracellular calcium handling in force-interval relationships of human ventricular myocardium. J Clin Invest 85, 1599-1613.
16. Harris SP, Bartley CR, Hacker TA, McDonald KS, Douglas PS, Greaser ML, Powers PA & Moss RL (2002). Hypertrophic cardiomyopathy in cardiac myosin binding protein-C knockout mice. Circ Res 90, 594-601.
17. Janssen PM, Datz N, Zeitz O & Hasenfuss G (2000). Levosimendan improves diastolic and systolic function in failing human myocardium. Eur J Pharmacol 404, 191-199.
18. Janssen PM, Stull LB & Marban E (2002). Myofilament properties comprise the rate-limiting step for cardiac relaxation at body temperature in the rat. Am J Physiol Heart Circ Physiol 282, H499-H507.
19. Jweied EE, McKinney RD, Walker LA, Brodsky I, Geha AS, Massad MG, Buttrick PM & de Tombe PP (2005). Depressed cardiac myofilament function in human diabetes mellitus. Am J Physiol Heart Circ Physiol 289, H2478-H2483.
20. Kameyama T, Chen Z, Bell SP, VanBuren P, Maughan D & LeWinter MM (1998). Mechanoenergetic alterations during the transition from cardiac hypertrophy to failure in Dahl salt-sensitive rats. Circulation 98, 2919-2929.
21. Kobayashi T, Yang X, Walker LA, Van Breemen RB & Solaro RJ (2005). A non-equilibrium isoelectric focusing method to determine states of phosphorylation of cardiac troponin I: Identification of Ser-23 and Ser-24 as significant sites of phosphorylation by protein kinase C. J Mol Cell Cardiol 38, 213-218.
22. Kogler H, Hartmann O, Leineweber K, Nguyen van P, Schott P, Brodde OE & Hasenfuss G (2003). Mechanical load-dependent regulation of gene expression in monocrotaline induced right ventricular hypertrophy in the rat. Circ Res 93, 230-237.
23. Korstjens IJ, Rouws CH, van der Laarse WJ, Van der Zee L & Stienen GJM (2002). Myocardial force development and structural changes associated with monocrotaline induced cardiac hypertrophy and heart failure. J Muscle Res Cell Motil 23, 93-102.
24. Lamberts RR, Vaessen RJ, Westerhof N & Stienen GJM (2007). Right ventricular hypertrophy causes impairment of left ventricular diastolic function in the rat. Basic Res Cardiol 102, 19-27.
25. Lamberts RR, Van Rijen MH, Sipkema P, Fransen P, Sys SU & Westerhof N (2002). Coronary perfusion and muscle lengthening increase cardiac contraction: Different stretch triggered mechanisms. Am J Physiol Heart Circ Physiol 283, H1515-H1522.
26. i - frequency relationships in rat ventricular trabeculae at physiological frequencies. Am J Physiol Heart Circ Physiol 276, H9-H18.
27. Layland J & Kentish JC (2002). Myofilament-based relaxant effect of isoprenaline revealed during work-loop contractions in rat cardiac trabeculae. J Physiol 544, 171-182.
28. Leineweber K, Seyfarth T & Brodde OE (2000). Chamber-specific alterations of noradrenaline uptake (uptake 1) in right ventricles of monocrotaline-treated rats. Br J Pharmacol 131, 1438-1444.
29. Lewartowski B & Pytkowski B (1987). Cellular mechanism of the relationship between myocardial force and frequency of contractions. Prog Biophys Mol Biol 50, 97-120.
30. Lim HW & Molkentin JD (1999). Calcineurin and human heart failure. Nat Med 5, 246-247.
31. Madden MS (1995). Reverse isoelectric focusing procedure resolves charge variants of basic proteins. Anal Biochem 229, 203-206.
32. Morano I, Arndt H, Gartner C & Ruegg JC (1988). Skinned fibers of human atrium and ventricle: Myosin isoenzymes and contractility. Circ Res 62, 632-639.
33. Morano I, Hadicke K, Haase H, Bohm M, Erdmann E & Schaub MC (1997). Changes in essential myosin light chain isoform expression provide a molecular basis for isometric force regulation in the failing human heart. J Mol Cell Cardiol 29, 1177-1187.
34. Mulieri LA, Hasenfuss G, Leavitt B, Allen PD & Alpert NR (1992). Altered myocardial force-frequency relation in human heart failure. Circulation 85, 1743-1750.
35. 2+-stimulated MgATPase of reconstituted actomyosin S-1. J Biol Chem 270, 25445-25454.
36. O'Farrell PZ, Goodman HM & O'Farrell PH (1977). High resolution two-dimensional electrophoresis of basic as well as acidic proteins. Cell 12, 1133-1141.
37. 2+ sensitivity of force and activation dependence of the kinetics of myocardial force development. Am J Physiol Heart Circ Physiol 287, H2712-H2718.
38. Pieske B, Kretschmann B, Meyer M, Holubarsch C, Weirich J, Posival H, Minami K, Just H & Hasenfuss G (1995). Alterations in intracellular calcium handling associated with the inverse force-frequency relation in human dilated cardiomyopathy. Circulation 92, 1169-1178.
39. 2+ content in isolated failing and nonfailing human myocardium. Circ Res 85, 38-46.
40. Schwinger RH, Bohm M, Muller-Ehmsen J, Uhlmann R, Schmidt U, Stablein A, Uberfuhr P, Kreuzer E, Reichart B & Eissner HJ (1993). Effect of inotropic stimulation on the negative force-frequency relationship in the failing human heart. Circulation 88, 2267-2276.
41. Seyfarth T, Gerbershagen HP, Giessler C, Leineweber K, Heinroth-Hoffmann I, Ponicke K & Brodde OE (2000). The cardiac β-adrenoceptor-G-protein(s)-adenylyl cyclase system in monocrotaline-treated rats. J Mol Cell Cardiol 32, 2315-2326.
42. Silver PJ, Buja LM & Stull JT (1986). Frequency-dependent myosin light chain phosphorylation in isolated myocardium. J Mol Cell Cardiol 18, 31-37.
43. Stelzer JE, Patel JR & Moss RL (2006). Acceleration of stretch activation in murine myocardium due to phosphorylation of myosin regulatory light chain. J Gen Physiol 128, 261-272.
44. Strang KT, Sweitzer NK, Greaser ML & Moss RL (1994). β-Adrenergic receptor stimulation increases unloaded shortening velocity of skinned single ventricular myocytes from rats. Circ Res 74, 542-549.
45. 2+ on force generation by mouse cardiac muscle. J Physiol 544, 817-830.
46. Sweeney HL, Bowman BF & Stull JT (1993). Myosin light chain phosphorylation in vertebrate striated muscle: Regulation and function. Am J Physiol Cell Physiol 264, C1085-C1095.
47. Swiderek K, Jaquet K, Meyer HE, Schachtele C, Hofmann F & Heilmeyer LM Jr (1990). Sites phosphorylated in bovine cardiac troponin T and I. Characterization by 31 P-NMR spectroscopy and phosphorylation by protein kinases. Eur J Biochem 190, 575-582.
48. Takimoto E, Soergel DG, Janssen PM, Stull LB, Kass DA & Murphy AM (2004). Frequency- and afterload-dependent cardiac modulation in vivo by troponin I with constitutively active protein kinase A phosphorylation sites. Circ Res 94, 496-504.
49. 2+ exchange. Can J Physiol Pharmacol 65, 619-626.
50. Tong CW, Gaffin RD, Zawieja DC & Muthuchamy M (2004). Roles of phosphorylation of myosin binding protein-C and troponin I in mouse cardiac muscle twitch dynamics. J Physiol 558, 927-941.
51. van der Velden J, Klein LJ, van der Bijl M, Huybregts MA, Stooker W, Witkop J, Eijsman L, Visser CA, Visser FC & Stienen GJM (1998). Force production in mechanically isolated cardiac myocytes from human ventricular muscle tissue. Cardiovasc Res 38, 414-423.
52. van der Velden J, Klein LJ, van der Bijl M, Huybregts MA, Stooker W, Witkop J, Eijsman L, Visser CA, Visser FC & Stienen GJM (1999). Isometric tension development and its calcium sensitivity in skinned myocyte-sized preparations from different regions of the human heart. Cardiovasc Res 42, 706-719.
53. van der Velden J, Klein LJ, Zaremba R, Boontje NM, Huybregts MA, Stooker W, Eijsman L, de Jong JW, Visser CA, Visser FC & Stienen GJM (2001). Effects of calcium, inorganic phosphate, and pH on isometric force in single skinned cardiomyocytes from donor and failing human hearts. Circulation 104, 1140-1146.
54. 2+ sensitivity of force is enhanced in failing human hearts. Cardiovasc Res 57, 505-514.
55. 2+ -sensitivity of the contractile apparatus in end-stage human heart failure results from altered phosphorylation of contractile proteins. Cardiovasc Res 57, 37-47.
56. Varian KD & Janssen PM (2007). Frequency dependent acceleration of relaxation involves decreased myofilament calcium sensitivity. Am J Physiol Heart Circ Physiol 292, H2212-2219.
57. Wolff MR, Buck SH, Stoker SW, Greaser ML & Mentzer RM (1996). Myofibrillar calcium sensitivity of isometric tension is increased in human dilated cardiomyopathies: Role of altered β-adrenergically mediated protein phosphorylation. J Clin Invest 98, 167-176.