-
1
-
-
33644850815
-
Antifibrotic agents for liver disease
-
Albanis E, Friedman SL. 2006. Antifibrotic agents for liver disease. Am J Transplant 6:12-19.
-
(2006)
Am J Transplant
, vol.6
, pp. 12-19
-
-
Albanis, E.1
Friedman, S.L.2
-
2
-
-
0037039374
-
Effects of peroxisome proliferator-activated receptor delta on placentation, adiposity, and colorectal cancer
-
DOI 10.1073/pnas.012610299
-
Barak Y, Liao D, He W, Ong ES, Nelson MC, Olefsky JM, Boland R, Evans RM. 2002. Effects of peroxisome proliferator-activated receptor delta on placentation, adiposity, and colorectal cancer. Proc Natl Acad Sci USA 99:303-308. (Pubitemid 34060358)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.1
, pp. 303-308
-
-
Barak, Y.1
Liao, D.2
He, W.3
Ong, E.S.4
Nelson, M.C.5
Olefsky, J.M.6
Boland, R.7
Evans, R.M.8
-
4
-
-
33751545838
-
A placebo-controlled trial of pioglitazone in subjects with nonalcoholic steatohepatitis
-
DOI 10.1056/NEJMoa060326
-
Belfort R, Harrison SA, Brown K, Darland C, Finch J, Hardies J, Balas B, Gastaldelli A, Tio F, Pulcini J, Berria R, Ma JZ, Dwivedi S, Havranek R, Fincke C, DeFronzo R, Bannayan GA, Schenker S, Cusi K. 2006. A placebo-controlled trial of pioglitazone in subjects with nonalcoholic steatohepatitis. N Engl J Med 355:2297-2307. (Pubitemid 44837778)
-
(2006)
New England Journal of Medicine
, vol.355
, Issue.22
, pp. 2297-2307
-
-
Belfort, R.1
Harrison, S.A.2
Brown, K.3
Darland, C.4
Finch, J.5
Hardies, J.6
Balas, B.7
Gastaldelli, A.8
Tio, F.9
Pulcini, J.10
Berria, R.11
Ma, J.Z.12
Dwivedi, S.13
Havranek, R.14
Fincke, C.15
Defronzo, R.16
Bannayan, G.A.17
Schenker, S.18
Cusi, K.19
-
5
-
-
27844522733
-
Disruption of intermolecular disulfide bonds in PDGF-BB dimers by N-acetyl-L-cysteine does not prevent PDGF signaling in cultured hepatic stellate cells
-
DOI 10.1016/j.bbrc.2005.10.139, PII S0006291X05024319
-
Borkham-Kamphorst E, Meurer SK, Gressner AM, Weiskirchen R. 2005. Disruption of intermolecular disulfide bonds in PDGF-BB dimers by N-acetyl-L-cysteine does not prevent PDGF signaling in cultured hepatic stellate cells. Biochem Biophys Res Commun 338:1711-1718. (Pubitemid 41643080)
-
(2005)
Biochemical and Biophysical Research Communications
, vol.338
, Issue.4
, pp. 1711-1718
-
-
Borkham-Kamphorst, E.1
Meurer, S.K.2
Gressner, A.M.3
Weiskirchen, R.4
-
6
-
-
57349116772
-
Prolonged therapy of advanced chronic hepatitis C with low-dose peginterferon
-
Di Bisceglie AM, Shiffman ML, Everson GT, Lindsay KL, Everhart JE, Wright EC, Lee WM, Lok AS, Bonkovsky HL, Morgan TR, et al. 2008. Prolonged therapy of advanced chronic hepatitis C with low-dose peginterferon. N Engl J Med 359:2429-2441.
-
(2008)
N Engl J Med
, vol.359
, pp. 2429-2441
-
-
Di Bisceglie, A.M.1
Shiffman, M.L.2
Everson, G.T.3
Lindsay, K.L.4
Everhart, J.E.5
Wright, E.C.6
Lee, W.M.7
Lok, A.S.8
Bonkovsky, H.L.9
Morgan, T.R.10
-
7
-
-
35248848237
-
Antioxidant therapy for chronic hepatitis C after failure of interferon: Results of phase II randomized, double-blind placebo controlled clinical trial
-
Gabbay E, Zigmond E, Pappo O, Hemed N, Rowe M, Zabrecky G, Cohen R, Ilan Y. 2007. Antioxidant therapy for chronic hepatitis C after failure of interferon: results of phase II randomized, double-blind placebo controlled clinical trial. World J Gastroenterol 13:5317-5323. (Pubitemid 47559461)
-
(2007)
World Journal of Gastroenterology
, vol.13
, Issue.40
, pp. 5317-5323
-
-
Gabbay, E.1
Zigmond, E.2
Pappo, O.3
Hemed, N.4
Rowe, M.5
Zabrecky, G.6
Cohen, R.7
Ilan, Y.8
-
8
-
-
0036257518
-
Oxidative stress, plant-derived antioxidants and liver fibrosis
-
DOI 10.1055/s-2002-26761
-
Gebhardt R. 2002. Oxidative stress, plant-derived antioxidants and liver fibrosis. Planta Med 68:289-296. (Pubitemid 34494036)
-
(2002)
Planta Medica
, vol.68
, Issue.4
, pp. 289-296
-
-
Gebhardt, R.1
-
10
-
-
43549113326
-
Quantitative expression patterns of peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) protein in mice
-
Girroir EE, Hollingshead HE, He P, Zhu B, Perdew GH, Peters JM. 2008. Quantitative expression patterns of peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) protein in mice. Biochem Biophys Res Commun 371:456-461.
-
(2008)
Biochem Biophys Res Commun
, vol.371
, pp. 456-461
-
-
Girroir, E.E.1
Hollingshead, H.E.2
He, P.3
Zhu, B.4
Perdew, G.H.5
Peters, J.M.6
-
11
-
-
0037221210
-
Peroxisome proliferator-activated receptor-beta signaling contributes to enhanced proliferation of hepatic stellate cells
-
DOI 10.1053/gast.2003.50015
-
Hellemans K, Michalik L, Dittie A, Knorr A, Rombouts K, De Jong J, Heirman C, Quartier E, Schuit F, Wahli W, et al. 2003. Peroxisome proliferator-activated receptor-beta signaling contributes to enhanced proliferation of hepatic stellate cells. Gastroenterology 124:184-201. (Pubitemid 36055351)
-
(2003)
Gastroenterology
, vol.124
, Issue.1
, pp. 184-201
-
-
Hellemans, K.1
Michalik, L.2
Dittie, A.3
Knorr, A.4
Rombouts, K.5
De Jong, J.6
Heirman, C.7
Quartier, E.8
Schuit, F.9
Wahli, W.10
Geerts, A.11
-
12
-
-
44349112305
-
Adipocyte-Derived Th2 Cytokines and Myeloid PPARdelta Regulate Macrophage Polarization and Insulin Sensitivity
-
DOI 10.1016/j.cmet.2008.04.002, PII S1550413108001125
-
Kang K, Reilly SM, Karabacak V, Gangl MR, Fitzgerald K, Hatano B, Lee CH. 2008. Adipocyte-derived Th2 cytokines and myeloid PPARdelta regulate macrophage polarization and insulin sensitivity. Cell Metab 7:485-495. (Pubitemid 351729204)
-
(2008)
Cell Metabolism
, vol.7
, Issue.6
, pp. 485-495
-
-
Kang, K.1
Reilly, S.M.2
Karabacak, V.3
Gangl, M.R.4
Fitzgerald, K.5
Hatano, B.6
Lee, C.-H.7
-
13
-
-
34247510652
-
The PPARdelta agonist GW501516 suppresses interleukin-6-mediated hepatocyte acute phase reaction via STAT3 inhibition
-
DOI 10.1111/j.1365-2362.2007.01796.x
-
Kino T, Rice KC, Chrousos GP. 2007. The PPARdelta agonist GW501516 suppresses interleukin-6-mediated hepatocyte acute phase reaction via STAT3 inhibition. Eur J Clin Invest 37:425-433. (Pubitemid 46653139)
-
(2007)
European Journal of Clinical Investigation
, vol.37
, Issue.5
, pp. 425-433
-
-
Kino, T.1
Rice, K.C.2
Chrousos, G.P.3
-
14
-
-
27144555677
-
Inhibition of adult liver progenitor (oval) cell growth and viability by an agonist of the peroxisome proliferator activated receptor (PPAR) family member gamma, but not alpha or delta
-
Knight B, Yeap BB, Yeoh GC, Olynyk JK. 2005. Inhibition of adult liver progenitor (oval) cell growth and viability by an agonist of the peroxisome proliferator activated receptor (PPAR) family member gamma, but not alpha or delta. Carcinogenesis 26:1782-1792.
-
(2005)
Carcinogenesis
, vol.26
, pp. 1782-1792
-
-
Knight, B.1
Yeap, B.B.2
Yeoh, G.C.3
Olynyk, J.K.4
-
15
-
-
33644766913
-
PPARdelta regulates glucose metabolism and insulin sensitivity
-
DOI 10.1073/pnas.0511253103
-
Lee CH, Olson P, Hevener A, Mehl I, Chong LW, Olefsky JM, Gonzalez FJ, Ham J, Kang H, Peters JM, et al. 2006. PPARdelta regulates glucose metabolism and insulin sensitivity. Proc Natl Acad Sci USA 103:3444-3449. (Pubitemid 43346488)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.9
, pp. 3444-3449
-
-
Lee, C.-H.1
Olson, P.2
Hevener, A.3
Mehl, I.4
Chong, L.-W.5
Olefsky, J.M.6
Gonzalez, F.J.7
Ham, J.8
Kang, H.9
Peters, J.M.10
Evans, R.M.11
-
17
-
-
33645891166
-
Effects of bezafibrate, PPAR pan-agonist, and GW501516, PPARdelta agonist, on development of steatohepatitis in mice fed a methionine- and choline-deficient diet
-
Nagasawa T, Inada Y, Nakano S, Tamura T, Takahashi T, Maruyama K, Yamazaki Y, Kuroda J, Shibata N. 2006. Effects of bezafibrate, PPAR pan-agonist, and GW501516, PPARdelta agonist, on development of steatohepatitis in mice fed a methionine- and choline-deficient diet. Eur J Pharmacol 536:182-191.
-
(2006)
Eur J Pharmacol
, vol.536
, pp. 182-191
-
-
Nagasawa, T.1
Inada, Y.2
Nakano, S.3
Tamura, T.4
Takahashi, T.5
Maruyama, K.6
Yamazaki, Y.7
Kuroda, J.8
Shibata, N.9
-
18
-
-
48449094498
-
AMPK and PPARdelta agonists are exercise mimetics
-
Narkar VA, Downes M, Yu RT, Embler E, Wang YX, Banayo E, Mihaylova MM, Nelson MC, Zou Y, Juguilon H, et al. 2008. AMPK and PPARdelta agonists are exercise mimetics. Cell 134:405-415.
-
(2008)
Cell
, vol.134
, pp. 405-415
-
-
Narkar, V.A.1
Downes, M.2
Yu, R.T.3
Embler, E.4
Wang, Y.X.5
Banayo, E.6
Mihaylova, M.M.7
Nelson, M.C.8
Zou, Y.9
Juguilon, H.10
-
19
-
-
0141532275
-
Improved nonalcoholic steatohepatitis after 48 weeks of treatment with the PPAR-gamma ligand rosiglitazone
-
DOI 10.1053/jhep.2003.50420
-
Neuschwander-Tetri BA, Brunt EM, Wehmeier KR, Oliver D, Bacon BR. 2003. Improved nonalcoholic steatohepatitis after 48 weeks of treatment with the PPAR-gamma ligand rosiglitazone. Hepatology 38:1008-1017. (Pubitemid 37221684)
-
(2003)
Hepatology
, vol.38
, Issue.4
, pp. 1008-1017
-
-
Neuschwander-Tetri, B.A.1
Brunt, E.M.2
Wehmeier, K.R.3
Oliver, D.4
Bacon, B.R.5
-
20
-
-
44349161098
-
Alternative M2 Activation of Kupffer Cells by PPARdelta Ameliorates Obesity-Induced Insulin Resistance
-
DOI 10.1016/j.cmet.2008.04.003, PII S1550413108001137
-
Odegaard JI, Ricardo-Gonzalez RR, Red Eagle A, Vats D, Morel CR, Goforth MH, Subramanian V, Mukundan L, Ferrante AW, Chawla A. 2008. Alternative M2 activation of Kupffer cells by PPARdelta ameliorates obesity-induced insulin resistance. Cell Metab 7:496-507. (Pubitemid 351729205)
-
(2008)
Cell Metabolism
, vol.7
, Issue.6
, pp. 496-507
-
-
Odegaard, J.I.1
Ricardo-Gonzalez, R.R.2
Red Eagle, A.3
Vats, D.4
Morel, C.R.5
Goforth, M.H.6
Subramanian, V.7
Mukundan, L.8
Ferrante, A.W.9
Chawla, A.10
-
21
-
-
67349255861
-
PPARdelta agonist attenuates alcohol-induced hepatic insulin resistance and improves liver injury and repair
-
Pang M, de la Monte SM, Longato L, Tong M, He J, Chaudhry R, Duan K, Ouh J, Wands JR. 2009. PPARdelta agonist attenuates alcohol-induced hepatic insulin resistance and improves liver injury and repair. J Hepatol 50:1192-1201.
-
(2009)
J Hepatol
, vol.50
, pp. 1192-1201
-
-
Pang, M.1
De La Monte, S.M.2
Longato, L.3
Tong, M.4
He, J.5
Chaudhry, R.6
Duan, K.7
Ouh, J.8
Wands, J.R.9
-
22
-
-
33645112691
-
The toxicology of ligands for peroxisome proliferator-activated receptors (PPAR)
-
Peraza MA, Burdick AD, Marin HE, Gonzalez FJ, Peters JM. 2006. The toxicology of ligands for peroxisome proliferator-activated receptors (PPAR). Toxicol Sci 90:269-295.
-
(2006)
Toxicol Sci
, vol.90
, pp. 269-295
-
-
Peraza, M.A.1
Burdick, A.D.2
Marin, H.E.3
Gonzalez, F.J.4
Peters, J.M.5
-
23
-
-
70349177505
-
Sorting out the functional role(s) of peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) in cell proliferation and cancer
-
Peters JM, Gonzalez FJ. 2009. Sorting out the functional role(s) of peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) in cell proliferation and cancer. Biochim Biophys Acta 1796:230-241.
-
(2009)
Biochim Biophys Acta
, vol.1796
, pp. 230-241
-
-
Peters, J.M.1
Gonzalez, F.J.2
-
24
-
-
0033625677
-
Growths, adipose, brain, and skin alterations resulting from targeted disruption of the mouse peroxisome proliferator-activated receptor beta(delta)
-
DOI 10.1128/MCB.20.14.5119-5128.2000
-
Peters JM, Lee SS, Li W, Ward JM, Gavrilova O, Everett C, Reitman ML, Hudson LD, Gonzalez FJ. 2000. Growth, adipose, brain, and skin alterations resulting from targeted disruption of the mouse peroxisome proliferator- activated receptor beta(delta). Mol Cell Biol 20:5119-5128. (Pubitemid 30431565)
-
(2000)
Molecular and Cellular Biology
, vol.20
, Issue.14
, pp. 5119-5128
-
-
Peters, J.M.1
Lee, S.S.T.2
Li, W.3
Ward, J.M.4
Gavrilova, O.5
Everett, C.6
Reitman, M.L.7
Hudson, L.D.8
Gonzalez, F.J.9
-
25
-
-
63149088164
-
Trophic macrophages in development and disease
-
Pollard JW. 2009. Trophic macrophages in development and disease. Nat Rev Immunol 9:259-270.
-
(2009)
Nat Rev Immunol
, vol.9
, pp. 259-270
-
-
Pollard, J.W.1
-
26
-
-
0036242165
-
Impact of pegylated interferon alfa-2b and ribavirin on liver fibrosis in patients with chronic hepatitis C
-
Poynard T, McHutchison J, Manns M, Trepo C, Lindsay K, Goodman Z, Ling MH, Albrecht J. 2002. Impact of pegylated interferon alfa-2b and ribavirin on liver fibrosis in patients with chronic hepatitis C. Gastroenterology 122:1303-1313. (Pubitemid 34465173)
-
(2002)
Gastroenterology
, vol.122
, Issue.5
, pp. 1303-1313
-
-
Poynard, T.1
McHutchison, J.2
Manns, M.3
Trepo, C.4
Lindsay, K.5
Goodman, Z.6
Ling, M.7
Albrecht, J.8
-
27
-
-
49649129066
-
Peroxisome proliferator-activated receptor-delta induces insulin-induced gene-1 and suppresses hepatic lipogenesis in obese diabetic mice
-
Qin X, Xie X, Fan Y, Tian J, Guan Y, Wang X, Zhu Y, Wang N. 2008. Peroxisome proliferator-activated receptor-delta induces insulin-induced gene-1 and suppresses hepatic lipogenesis in obese diabetic mice. Hepatology 48:432-441.
-
(2008)
Hepatology
, vol.48
, pp. 432-441
-
-
Qin, X.1
Xie, X.2
Fan, Y.3
Tian, J.4
Guan, Y.5
Wang, X.6
Zhu, Y.7
Wang, N.8
-
28
-
-
37349007681
-
PPARdelta as a therapeutic target in metabolic disease
-
DOI 10.1016/j.febslet.2007.11.040, PII S0014579307011842
-
Reilly SM, Lee CH. 2008. PPAR delta as a therapeutic target in metabolic disease. FEBS Lett 582:26-31. (Pubitemid 350297247)
-
(2008)
FEBS Letters
, vol.582
, Issue.1
, pp. 26-31
-
-
Reilly, S.M.1
Lee, C.-H.2
-
29
-
-
4544342831
-
Beneficial effect of angiotensin-blocking agents on graft fibrosis in hepatitis C recurrence after liver transplantation
-
DOI 10.1097/01.TP.0000128913.09774.CE
-
Rimola A, Londono MC, Guevara G, Bruguera M, Navasa M, Forns X, Garcia-Retortillo M, Garcia-Valdecasas JC, Rodes J. 2004. Beneficial effect of angiotensin-blocking agents on graft fibrosis in hepatitis C recurrence after liver transplantation. Transplantation 78:686-691. (Pubitemid 39244729)
-
(2004)
Transplantation
, vol.78
, Issue.5
, pp. 686-691
-
-
Rimola, A.1
Londono, M.-C.2
Guevara, G.3
Bruguera, M.4
Navasa, M.5
Forns, X.6
Garcia-Retortillo, M.7
Garcia-Valdecasas, J.-C.8
Rodes, J.9
-
30
-
-
39649101196
-
Activation of peroxisome proliferator-activated receptor (PPAR)delta promotes reversal of multiple metabolic abnormalities, reduces oxidative stress, and increases fatty acid oxidation in moderately obese men
-
Riserus U, Sprecher D, Johnson T, Olson E, Hirschberg S, Liu A, Fang Z, Hegde P, Richards D, Sarov-Blat L, et al. 2008. Activation of peroxisome proliferator-activated receptor (PPAR)delta promotes reversal of multiple metabolic abnormalities, reduces oxidative stress, and increases fatty acid oxidation in moderately obese men. Diabetes 57:332-339.
-
(2008)
Diabetes
, vol.57
, pp. 332-339
-
-
Riserus, U.1
Sprecher, D.2
Johnson, T.3
Olson, E.4
Hirschberg, S.5
Liu, A.6
Fang, Z.7
Hegde, P.8
Richards, D.9
Sarov-Blat, L.10
-
31
-
-
54549119172
-
Current and future anti-fibrotic therapies for chronic liver disease
-
xi.
-
Rockey DC. 2008. Current and future anti-fibrotic therapies for chronic liver disease. Clin Liver Dis 12:939-962, xi.
-
(2008)
Clin Liver Dis
, vol.12
, pp. 939-962
-
-
Rockey, D.C.1
-
32
-
-
51349156218
-
Insulin sensitivity: Modulation by nutrients and inflammation
-
Schenk S, Saberi M, Olefsky JM. 2008. Insulin sensitivity: modulation by nutrients and inflammation. J Clin Invest 118:2992-3002.
-
(2008)
J Clin Invest
, vol.118
, pp. 2992-3002
-
-
Schenk, S.1
Saberi, M.2
Olefsky, J.M.3
-
33
-
-
0034956559
-
The role of Smad3 in mediating mouse hepatic stellate cell activation
-
DOI 10.1053/jhep.2001.25349
-
Schnabl B, Kweon YO, Frederick JP, Wang XF, Rippe RA, Brenner DA. 2001. The role of Smad3 in mediating mouse hepatic stellate cell activation. Hepatology 34:89-100. (Pubitemid 32591487)
-
(2001)
Hepatology
, vol.34
, Issue.1
, pp. 89-100
-
-
Schnabl, B.1
Kweon, Y.O.2
Frederick, J.P.3
Wang, X.-F.4
Rippe, R.A.5
Brenner, D.A.6
-
34
-
-
0037370003
-
Replicative senescence of activated human hepatic stellate cells is accompanied by a pronounced inflammatory but less fibrogenic phenotype
-
DOI 10.1053/jhep.2003.50097
-
Schnabl B, Purbeck CA, Choi YH, Hagedorn CH, Brenner DA. 2003. Replicative senescence of activated human hepatic stellate cells is accompanied by a pronounced inflammatory but less fibrogenic phenotype. Hepatology 37:653-664. (Pubitemid 36258787)
-
(2003)
Hepatology
, vol.37
, Issue.3
, pp. 653-664
-
-
Schnabl, B.1
Purbeck, C.A.2
Choi, Y.H.3
Hagedorn, C.H.4
Brenner, D.A.5
-
35
-
-
51349157015
-
What is the potential role of antifibrotic agents for the treatment of liver disease?
-
Schnabl B, Scholten D, Brenner DA. 2008. What is the potential role of antifibrotic agents for the treatment of liver disease? Nat Clin Pract Gastroenterol Hepatol 5:496-497.
-
(2008)
Nat Clin Pract Gastroenterol Hepatol
, vol.5
, pp. 496-497
-
-
Schnabl, B.1
Scholten, D.2
Brenner, D.A.3
-
36
-
-
33750427891
-
PGC1alpha expression is controlled in skeletal muscles by PPARbeta, whose ablation results in fiber-type switching, obesity, and type 2 diabetes
-
DOI 10.1016/j.cmet.2006.10.003, PII S1550413106003317
-
Schuler M, Ali F, Chambon C, Duteil D, Bornert JM, Tardivel A, Desvergne B, Wahli W, Chambon P, Metzger D. 2006. PGC1alpha expression is controlled in skeletal muscles by PPARbeta, whose ablation results in fiber-type switching, obesity, and type 2 diabetes. Cell Metab 4:407-414. (Pubitemid 44645068)
-
(2006)
Cell Metabolism
, vol.4
, Issue.5
, pp. 407-414
-
-
Schuler, M.1
Ali, F.2
Chambon, C.3
Duteil, D.4
Bornert, J.-M.5
Tardivel, A.6
Desvergne, B.7
Wahli, W.8
Chambon, P.9
Metzger, D.10
-
37
-
-
38649104434
-
Peroxisome proliferator-activated receptor-beta/delta protects against chemically induced liver toxicity in mice
-
DOI 10.1002/hep.21925
-
Shan W, Nicol CJ, Ito S, Bility MT, Kennett MJ, Ward JM, Gonzalez FJ, Peters JM. 2008a. Peroxisome proliferator-activated receptor-beta/delta protects against chemically induced liver toxicity in mice. Hepatology 47:225-235. (Pubitemid 351171060)
-
(2008)
Hepatology
, vol.47
, Issue.1
, pp. 225-235
-
-
Shan, W.1
Nicol, C.J.2
Ito, S.3
Bility, M.T.4
Kennett, M.J.5
Ward, J.M.6
Gonzalez, F.J.7
Peters, J.M.8
-
38
-
-
51849123779
-
Ligand activation of peroxisome proliferator-activated receptor beta/delta (PPARbeta/delta) attenuates carbon tetrachloride hepatotoxicity by downregulating proinflammatory gene expression
-
Shan W, Palkar PS, Murray IA, McDevitt EI, Kennett MJ, Kang BH, Isom HC, Perdew GH, Gonzalez FJ, Peters JM. 2008b. Ligand activation of peroxisome proliferator-activated receptor beta/delta (PPARbeta/delta) attenuates carbon tetrachloride hepatotoxicity by downregulating proinflammatory gene expression. Toxicol Sci 105:418-428.
-
(2008)
Toxicol Sci
, vol.105
, pp. 418-428
-
-
Shan, W.1
Palkar, P.S.2
Murray, I.A.3
McDevitt, E.I.4
Kennett, M.J.5
Kang, B.H.6
Isom, H.C.7
Perdew, G.H.8
Gonzalez, F.J.9
Peters, J.M.10
-
39
-
-
34547625616
-
The next generation of PPAR drugs: Do we have the tools to find them?
-
Shearer BG, Billin AN. 2007. The next generation of PPAR drugs: do we have the tools to find them? Biochim Biophys Acta 1771:1082-1093.
-
(2007)
Biochim Biophys Acta
, vol.1771
, pp. 1082-1093
-
-
Shearer, B.G.1
Billin, A.N.2
-
40
-
-
33846443997
-
Triglyceride: High-density lipoprotein cholesterol effects in healthy subjects administered a peroxisome proliferator activated receptor delta agonist
-
DOI 10.1161/01.ATV.0000252790.70572.0c, PII 0004360520070200000017
-
Sprecher DL, Massien C, Pearce G, Billin AN, Perlstein I, Willson TM, Hassall DG, Ancellin N, Patterson SD, Lobe DC, et al. 2007. Triglyceride:high- density lipoprotein cholesterol effects in healthy subjects administered a peroxisome proliferator activated receptor delta agonist. Arterioscler Thromb Vasc Biol 27:359-365. (Pubitemid 46143052)
-
(2007)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.27
, Issue.2
, pp. 359-365
-
-
Sprecher, D.L.1
Massien, C.2
Pearce, G.3
Billin, A.N.4
Perlstein, I.5
Willson, T.M.6
Hassall, D.G.7
Ancellin, N.8
Patterson, S.D.9
Lobe, D.C.10
Johnson, T.G.11
-
41
-
-
9144271149
-
Activation of peroxisome proliferator-activated receptor delta induces fatty acid beta-oxidation in skeletal muscle and attenuates metabolic syndrome
-
Tanaka T, Yamamoto J, Iwasaki S, Asaba H, Hamura H, Ikeda Y, Watanabe M, Magoori K, Ioka RX, Tachibana K, et al. 2003. Activation of peroxisome proliferator-activated receptor delta induces fatty acid beta-oxidation in skeletal muscle and attenuates metabolic syndrome. Proc Natl Acad Sci USA 100:15924-15929.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 15924-15929
-
-
Tanaka, T.1
Yamamoto, J.2
Iwasaki, S.3
Asaba, H.4
Hamura, H.5
Ikeda, Y.6
Watanabe, M.7
Magoori, K.8
Ioka, R.X.9
Tachibana, K.10
-
42
-
-
0032903634
-
Hepatocyte growth factor gene therapy of liver cirrhosis in rats
-
DOI 10.1038/5593
-
Ueki T, Kaneda Y, Tsutsui H, Nakanishi K, Sawa Y, Morishita R, Matsumoto K, Nakamura T, Takahashi H, Okamoto E, et al. 1999. Hepatocyte growth factor gene therapy of liver cirrhosis in rats. Nat Med 5:226-230. (Pubitemid 29068532)
-
(1999)
Nature Medicine
, vol.5
, Issue.2
, pp. 226-230
-
-
Ueki, T.1
Kaneda, Y.2
Tsutsui, H.3
Nakanishi, K.4
Sawa, Y.5
Morishita, R.6
Matsumoto, K.7
Nakamura, T.8
Takahashi, H.9
Okamoto, E.10
Fujimoto, J.11
-
43
-
-
0037453718
-
Peroxisome-proliferator-activated receptor delta activates fat metabolism to prevent obesity
-
Wang YX, Lee CH, Tiep S, Yu RT, Ham J, Kang H, Evans RM. 2003. Peroxisome-proliferator-activated receptor delta activates fat metabolism to prevent obesity. Cell 113:159-170.
-
(2003)
Cell
, vol.113
, pp. 159-170
-
-
Wang, Y.X.1
Lee, Ch.2
Tiep, S.3
Yu, R.T.4
Ham, J.5
Kang, H.6
Evans, R.M.7
-
44
-
-
7044222556
-
Therapeutic efficacy of an angiotensin II receptor antagonist in patients with nonalcoholic steatohepatitis
-
Yokohama S, Yoneda M, Haneda M, Okamoto S, Okada M, Aso K, Hasegawa T, Tokusashi Y, Miyokawa N, Nakamura K. 2004. Therapeutic efficacy of an angiotensin II receptor antagonist in patients with nonalcoholic steatohepatitis. Hepatology 40:1222-1225.
-
(2004)
Hepatology
, vol.40
, pp. 1222-1225
-
-
Yokohama, S.1
Yoneda, M.2
Haneda, M.3
Okamoto, S.4
Okada, M.5
Aso, K.6
Hasegawa, T.7
Tokusashi, Y.8
Miyokawa, N.9
Nakamura, K.10
|