메뉴 건너뛰기




Volumn 26, Issue 10, 2005, Pages 1782-1792

Inhibition of adult liver progenitor (oval) cell growth and viability by an agonist of the peroxisome proliferator activated receptor (PPAR) family member γ, but not α or δ

Author keywords

[No Author keywords available]

Indexed keywords

[2 METHYL 4 [4 METHYL 2 (4 TRIFLUOROMETHYLPHENYL) 5 THIAZOLYLMETHYLTHIO]PHENOXY]ACETIC ACID; CHOLINE; CIGLITAZONE; ETHIONINE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR AGONIST; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PIRINIXIC ACID;

EID: 27144555677     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgi138     Document Type: Article
Times cited : (37)

References (60)
  • 3
    • 0037213389 scopus 로고    scopus 로고
    • The role of hepatocytes and oval cells in liver regeneration and repopulation
    • Fausto,N. and Campbell,J.S. (2003) The role of hepatocytes and oval cells in liver regeneration and repopulation. Mech. Dev., 120, 117-130.
    • (2003) Mech. Dev. , vol.120 , pp. 117-130
    • Fausto, N.1    Campbell, J.S.2
  • 4
    • 0343387640 scopus 로고    scopus 로고
    • Early effects in chemical-induced rat liver carcinogenesis: An immunohistochemical study following exposure to 0.04% AAF
    • Hadjiolov,N. and Bitsch,A. (1997) Early effects in chemical-induced rat liver carcinogenesis: An immunohistochemical study following exposure to 0.04% AAF. Apoptosis, 2, 91-100.
    • (1997) Apoptosis , vol.2 , pp. 91-100
    • Hadjiolov, N.1    Bitsch, A.2
  • 5
    • 3242728437 scopus 로고    scopus 로고
    • Telomerase regulation and progressive telomere shortening of rat hepatic stem-like epithelial cells during in vitro aging
    • Oh,B.K., Lee,C.H., Park,C. and Park,Y.N. (2004) Telomerase regulation and progressive telomere shortening of rat hepatic stem-like epithelial cells during in vitro aging. Exp. Cell Res., 298, 445-454.
    • (2004) Exp. Cell Res. , vol.298 , pp. 445-454
    • Oh, B.K.1    Lee, C.H.2    Park, C.3    Park, Y.N.4
  • 6
    • 22944437771 scopus 로고    scopus 로고
    • Inflammation and cytokine, production, but not acute phase protein synthesis, accompany the liver progenitor (oval) cell response to chronic liver injury
    • in press
    • Knight,B., Matthews,V.B., Akhurst,B., Croager,E.J., Abraham,L.J., Olynyk,J.K. and Yeoh,G.C. (2005) Inflammation and cytokine, production, but not acute phase protein synthesis, accompany the liver progenitor (oval) cell response to chronic liver injury. Immunol. Cell Biol., in press.
    • (2005) Immunol. Cell Biol.
    • Knight, B.1    Matthews, V.B.2    Akhurst, B.3    Croager, E.J.4    Abraham, L.J.5    Olynyk, J.K.6    Yeoh, G.C.7
  • 7
    • 0032964899 scopus 로고    scopus 로고
    • Oval cell numbers in human chronic liver diseases are directly related to disease severity
    • Lowes,X.N., Brennan,B.A., Yeoh,G.C. and Olynyk,J.K. (1999) Oval cell numbers in human chronic liver diseases are directly related to disease severity. Am. J. Pathol., 154, 537-541.
    • (1999) Am. J. Pathol. , vol.154 , pp. 537-541
    • Lowes, X.N.1    Brennan, B.A.2    Yeoh, G.C.3    Olynyk, J.K.4
  • 8
    • 0026554967 scopus 로고
    • Persistence of the cholangiocellular and hepatocellular lesions observed in rats fed a choline-deficient/DL-ethionine-supplemented diet
    • Hacker,H.J., Steinberg,P., Toshkov,I., Oesch,F. and Bannasch,P. (1992) Persistence of the cholangiocellular and hepatocellular lesions observed in rats fed a choline-deficient/DL-ethionine-supplemented diet. Carcinogenesis, 13, 271-276.
    • (1992) Carcinogenesis , vol.13 , pp. 271-276
    • Hacker, H.J.1    Steinberg, P.2    Toshkov, I.3    Oesch, F.4    Bannasch, P.5
  • 9
    • 4444298586 scopus 로고    scopus 로고
    • Function of oval cells in hepatocellular carcinoma in rats
    • Fang,C.H., Gong,J.Q. and Zhang,W. (2004) Function of oval cells in hepatocellular carcinoma in rats. World J. Gastroenterol., 10, 2482-2487.
    • (2004) World J. Gastroenterol. , vol.10 , pp. 2482-2487
    • Fang, C.H.1    Gong, J.Q.2    Zhang, W.3
  • 10
    • 0025297612 scopus 로고
    • Expression of hepatocyte and oval cell antigens in hepatocellular carcinomas produced by oncogene-transfected liver epithelia] cells
    • Goyette,M., Faris,R., Braun,L., Hixson,D. and Fausto,N. (1990) Expression of hepatocyte and oval cell antigens in hepatocellular carcinomas produced by oncogene-transfected liver epithelia] cells. Cancer Res., 50, 4809-4817.
    • (1990) Cancer Res. , vol.50 , pp. 4809-4817
    • Goyette, M.1    Faris, R.2    Braun, L.3    Hixson, D.4    Fausto, N.5
  • 11
    • 0036210375 scopus 로고    scopus 로고
    • Generation and characterization of p53 null transformed hepatic progenitor cells: Oval cells give rise to hepatocellular carcinoma
    • Dumble,M.L., Croager,E.J., Yeoh,G.C. and Quail,E.A. (2002) Generation and characterization of p53 null transformed hepatic progenitor cells: oval cells give rise to hepatocellular carcinoma. Carcinogenesis, 23, 435-445.
    • (2002) Carcinogenesis , vol.23 , pp. 435-445
    • Dumble, M.L.1    Croager, E.J.2    Yeoh, G.C.3    Quail, E.A.4
  • 13
    • 0022402544 scopus 로고
    • Oncodevelopmental expression of rat placental alkaline phosphatase. Detection in oval cells during liver carcinogenesis
    • Yaswen,P., Thompson,N.L. and Fausto,N. (1985) Oncodevelopmental expression of rat placental alkaline phosphatase. Detection in oval cells during liver carcinogenesis. Am. J. Pathol., 121, 505-513.
    • (1985) Am. J. Pathol. , vol.121 , pp. 505-513
    • Yaswen, P.1    Thompson, N.L.2    Fausto, N.3
  • 14
    • 0021912710 scopus 로고
    • Expression of c-Ki-ras, c-Ha-ras, and c-myc in specific cell types during hepatocarcinogenesis
    • Yaswen,P., Goyette,M., Shank,P.R. and Fausto,N. (1985) Expression of c-Ki-ras, c-Ha-ras, and c-myc in specific cell types during hepatocarcinogenesis. Mol. Cell Biol., 5, 780-786.
    • (1985) Mol. Cell Biol. , vol.5 , pp. 780-786
    • Yaswen, P.1    Goyette, M.2    Shank, P.R.3    Fausto, N.4
  • 15
    • 0034684651 scopus 로고    scopus 로고
    • Impaired preneoplastic changes and liver tumor formation in tumor necrosis factor receptor type 1 knockout mice
    • Knight,B., Yeoh,G.C., Husk,K.L., Ly,T., Abraham,L.J., Yu,C., Rhim,J.A. and Fausto,N. (2000) Impaired preneoplastic changes and liver tumor formation in tumor necrosis factor receptor type 1 knockout mice. J. Exp. Med., 192, 1809-1818.
    • (2000) J. Exp. Med. , vol.192 , pp. 1809-1818
    • Knight, B.1    Yeoh, G.C.2    Husk, K.L.3    Ly, T.4    Abraham, L.J.5    Yu, C.6    Rhim, J.A.7    Fausto, N.8
  • 16
    • 0034569799 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors, coactivators, and downstream targets
    • Qi,C., Zhu,Y. and Reddy,J.K. (2000) Peroxisome proliferator-activated receptors, coactivators, and downstream targets. Cell Biochem. Biophys., 32, 187-204.
    • (2000) Cell Biochem. Biophys. , vol.32 , pp. 187-204
    • Qi, C.1    Zhu, Y.2    Reddy, J.K.3
  • 17
    • 0842263981 scopus 로고    scopus 로고
    • The biology of peroxisome proliferator-activated receptors: Relationship with lipid metabolism and insulin sensitivity
    • Ferre,P. (2004) The biology of peroxisome proliferator-activated receptors: Relationship with lipid metabolism and insulin sensitivity. Diabetes, 53 (Suppl. 1), S43-S50.
    • (2004) Diabetes , vol.53 , Issue.SUPPL. 1
    • Ferre, P.1
  • 18
    • 0030047806 scopus 로고    scopus 로고
    • Differential expression of peroxisome proliferator-activated receptors (PPARs): Tissue distribution of PPAR-alpha, -beta, and -gamma in the adult rat
    • Braissant,O., Foufelle,F., Scotto,C., Dauca,M. and Wahli,W. (1996) Differential expression of peroxisome proliferator-activated receptors (PPARs): Tissue distribution of PPAR-alpha, -beta, and -gamma in the adult rat. Endocrinology, 137, 354-366.
    • (1996) Endocrinology , vol.137 , pp. 354-366
    • Braissant, O.1    Foufelle, F.2    Scotto, C.3    Dauca, M.4    Wahli, W.5
  • 19
    • 0034532156 scopus 로고    scopus 로고
    • Expression of PPAR(alpha) in human hepatocytes and activation by trichloroacetate and dichloroacetate
    • Walgen,J.E., Kurtz,D.T. and McMillan,J.M. (2000) Expression of PPAR(alpha) in human hepatocytes and activation by trichloroacetate and dichloroacetate. Res. Commun. Mol. Pathol. Pharmacol., 108, 116-132.
    • (2000) Res. Commun. Mol. Pathol. Pharmacol. , vol.108 , pp. 116-132
    • Walgen, J.E.1    Kurtz, D.T.2    McMillan, J.M.3
  • 21
    • 0024241608 scopus 로고
    • Relationship of hepatic peroxisome proliferation and replicative DNA synthesis to the hepatocarcinogenicity of the peroxisome proliferators di(2-ethylhexyl)phthalate and [4-chloro-6-(2,3-xylidino) -2-pyrimidinylthio] acetic acid (Wy-14,643) in rats
    • Marsman,D.S., Cattley,R.C., Conway,J.G. and Popp,J.A. (1988) Relationship of hepatic peroxisome proliferation and replicative DNA synthesis to the hepatocarcinogenicity of the peroxisome proliferators di(2-ethylhexyl)phthalate and [4-chloro-6-(2,3-xylidino)-2-pyrimidinylthio] acetic acid (Wy-14,643) in rats. Cancer Res., 48, 6739-6744.
    • (1988) Cancer Res. , vol.48 , pp. 6739-6744
    • Marsman, D.S.1    Cattley, R.C.2    Conway, J.G.3    Popp, J.A.4
  • 22
    • 0035169452 scopus 로고    scopus 로고
    • Hepatocellular proliferation in response to a peroxisome proliferator does not require TNFalpha signaling
    • Anderson,S.P., Dunn,C.S., Cattley,R.C. and Corton,J.C. (2001) Hepatocellular proliferation in response to a peroxisome proliferator does not require TNFalpha signaling. Carcinogenesis, 22, 1843-1851.
    • (2001) Carcinogenesis , vol.22 , pp. 1843-1851
    • Anderson, S.P.1    Dunn, C.S.2    Cattley, R.C.3    Corton, J.C.4
  • 23
    • 0036730442 scopus 로고    scopus 로고
    • Delayed liver regeneration in peroxisome proliferator-activated receptor-alpha-null mice
    • Anderson,S.P., Yoon,L., Richard,E.B., Dunn,C.S., Cattley,R.C. and Corton,J.C. (2002) Delayed liver regeneration in peroxisome proliferator-activated receptor-alpha-null mice. Hepatology, 36, 544-554.
    • (2002) Hepatology , vol.36 , pp. 544-554
    • Anderson, S.P.1    Yoon, L.2    Richard, E.B.3    Dunn, C.S.4    Cattley, R.C.5    Corton, J.C.6
  • 24
    • 0036120125 scopus 로고    scopus 로고
    • Hepatic regeneration in peroxisome proliferator-activated receptor alpha-null mice after partial hepatectomy
    • Rao,M.S., Peters,J.M., Gonzalez,F.J. and Reddy,J.K. (2002) Hepatic regeneration in peroxisome proliferator-activated receptor alpha-null mice after partial hepatectomy. Hepatol. Res., 22, 52-57.
    • (2002) Hepatol. Res. , vol.22 , pp. 52-57
    • Rao, M.S.1    Peters, J.M.2    Gonzalez, F.J.3    Reddy, J.K.4
  • 25
    • 0030478960 scopus 로고    scopus 로고
    • Hepatocarcinogenesis of peroxisome proliferators
    • Rao,M.S. and Reddy,J.K. (1996) Hepatocarcinogenesis of peroxisome proliferators. Ann. N. Y. Acad. Sci., 804, 573-587.
    • (1996) Ann. N. Y. Acad. Sci. , vol.804 , pp. 573-587
    • Rao, M.S.1    Reddy, J.K.2
  • 26
    • 0035943681 scopus 로고    scopus 로고
    • Differential gene regulation in human versus rodent hepatocytes by peroxisome proliferator-activated receptor (PPAR) alpha. PPAR alpha fails to induce peroxisome proliferation-associated genes in human cells independently of the level of receptor expresson
    • Lawrence,J.W., Li,Y., Chen,S., DeLuca,J.G., Berger,J.P., Umbenhauer,D.R., Moller,D.E. and Zhou,G. (2001) Differential gene regulation in human versus rodent hepatocytes by peroxisome proliferator-activated receptor (PPAR) alpha. PPAR alpha fails to induce peroxisome proliferation-associated genes in human cells independently of the level of receptor expresson. J. Biol. Chem., 276, 31521-31527.
    • (2001) J. Biol. Chem. , vol.276 , pp. 31521-31527
    • Lawrence, J.W.1    Li, Y.2    Chen, S.3    DeLuca, J.G.4    Berger, J.P.5    Umbenhauer, D.R.6    Moller, D.E.7    Zhou, G.8
  • 27
    • 0033855572 scopus 로고    scopus 로고
    • Ligands of peroxisome proliferator-activated receptor gamma modulate profibrogenic and pro-inflammatory actions in hepatic stellate cells
    • Marra,F., Efsen,E., Romanelli,R.G. et al. (2000) Ligands of peroxisome proliferator-activated receptor gamma modulate profibrogenic and pro-inflammatory actions in hepatic stellate cells. Gastroenterology, 119, 466-478.
    • (2000) Gastroenterology , vol.119 , pp. 466-478
    • Marra, F.1    Efsen, E.2    Romanelli, R.G.3
  • 28
    • 0035200209 scopus 로고    scopus 로고
    • Activation of retinoic X receptor and peroxisome proliferator-activated receptor-gamma inhibits nitric oxide and tumor necrosis factor-alpha production in rat Kupffer cells
    • Uchimura,K., Nakamuta,M., Enjoji,M., Irie,T., Sugimoto,R., Muta,T., Iwamoto,H. and Nawata,H. (2001) Activation of retinoic X receptor and peroxisome proliferator-activated receptor-gamma inhibits nitric oxide and tumor necrosis factor-alpha production in rat Kupffer cells. Hepatology, 33, 91-99.
    • (2001) Hepatology , vol.33 , pp. 91-99
    • Uchimura, K.1    Nakamuta, M.2    Enjoji, M.3    Irie, T.4    Sugimoto, R.5    Muta, T.6    Iwamoto, H.7    Nawata, H.8
  • 29
    • 0041927816 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma ligands inhibit cell growth and induce apoptosis in human liver cancer BEL-7402 cells
    • Li,M.Y., Deng,H., Zhao,J.M., Dai,D. and Tan,X.Y. (2003) Peroxisome proliferator-activated receptor gamma ligands inhibit cell growth and induce apoptosis in human liver cancer BEL-7402 cells. World J. Gastroenterol., 9, 1683-1688.
    • (2003) World J. Gastroenterol. , vol.9 , pp. 1683-1688
    • Li, M.Y.1    Deng, H.2    Zhao, J.M.3    Dai, D.4    Tan, X.Y.5
  • 30
    • 0038389867 scopus 로고    scopus 로고
    • PPARgamma pathway activation results in apoptosis and COX-2 inhibition in HepG2 cells
    • Li,M.Y., Deng,H., Zhao,J.M., Dai,D. and Tan,X.Y. (2003) PPARgamma pathway activation results in apoptosis and COX-2 inhibition in HepG2 cells. World J. Gastroenterol., 9, 1220-1226.
    • (2003) World J. Gastroenterol. , vol.9 , pp. 1220-1226
    • Li, M.Y.1    Deng, H.2    Zhao, J.M.3    Dai, D.4    Tan, X.Y.5
  • 31
    • 6044267548 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma ligands, 15-deoxy-Delta 12,14-prostaglandin J2, and ciglitazone, induce growth inhibition and cell cycle arrest in hepatic oval cells
    • Cheng,J., Nakamura,H., Imanishi,H., Liu,W., Morisaki,T., Sugiyama,T. and Hada,T. (2004) Peroxisome proliferator-activated receptor gamma ligands, 15-deoxy-Delta 12,14-prostaglandin J2, and ciglitazone, induce growth inhibition and cell cycle arrest in hepatic oval cells. Biochem. Biophys. Res. Commun., 322, 458-464.
    • (2004) Biochem. Biophys. Res. Commun. , vol.322 , pp. 458-464
    • Cheng, J.1    Nakamura, H.2    Imanishi, H.3    Liu, W.4    Morisaki, T.5    Sugiyama, T.6    Hada, T.7
  • 32
    • 0842308111 scopus 로고    scopus 로고
    • Pioglitazone prevents hepatic steatosis, fibrosis, and enzyme-altered lesions in rat liver cirrhosis induced by a choline-deficient L-amino acid-defined diet
    • Kawaguchi,K., Sakaida,I., Tsuchiya,M., Omori,K., Takami,T. and Okita,K. (2004) Pioglitazone prevents hepatic steatosis, fibrosis, and enzyme-altered lesions in rat liver cirrhosis induced by a choline-deficient L-amino acid-defined diet. Biochem. Biophys. Res. Commun., 315, 187-195.
    • (2004) Biochem. Biophys. Res. Commun. , vol.315 , pp. 187-195
    • Kawaguchi, K.1    Sakaida, I.2    Tsuchiya, M.3    Omori, K.4    Takami, T.5    Okita, K.6
  • 33
    • 1442355447 scopus 로고    scopus 로고
    • A pilot study of pioglitazone treatment for nonalcoholic steatohepatitis
    • Promrat,K., Lutchman,G., Uwaifo,G.I. et al. (2004) A pilot study of pioglitazone treatment for nonalcoholic steatohepatitis. Hepatology, 39, 188-196.
    • (2004) Hepatology , vol.39 , pp. 188-196
    • Promrat, K.1    Lutchman, G.2    Uwaifo, G.I.3
  • 34
    • 0037221210 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-beta signaling contributes to enhanced proliferation of hepatic stellate cells
    • Hellemans,K., Michalik,L., Dittie,A. et al. (2003) Peroxisome proliferator-activated receptor-beta signaling contributes to enhanced proliferation of hepatic stellate cells. Gastroenterology, 124, 184-201.
    • (2003) Gastroenterology , vol.124 , pp. 184-201
    • Hellemans, K.1    Michalik, L.2    Dittie, A.3
  • 35
    • 0042388005 scopus 로고    scopus 로고
    • PPARdelta activation induces COX-2 gene expression and cell proliferation in human hepatocellular carcinoma cells
    • Glinghammar,B., Skogsberg,J., Hamsten,A. and Ehrenborg,E. (2003) PPARdelta activation induces COX-2 gene expression and cell proliferation in human hepatocellular carcinoma cells. Biochem. Biophys. Res. Commun., 308, 361-368.
    • (2003) Biochem. Biophys. Res. Commun. , vol.308 , pp. 361-368
    • Glinghammar, B.1    Skogsberg, J.2    Hamsten, A.3    Ehrenborg, E.4
  • 36
    • 0037453718 scopus 로고    scopus 로고
    • Peroxisome-proliferator-activated receptor delta activates fat metabolism to prevent obesity
    • Wang,Y.X., Lee,C.H., Tiep,S., Yu,R.T., Ham,J., Kang,H. and Evans,R.M. (2003) Peroxisome-proliferator-activated receptor delta activates fat metabolism to prevent obesity. Cell, 113, 159-170.
    • (2003) Cell , vol.113 , pp. 159-170
    • Wang, Y.X.1    Lee, C.H.2    Tiep, S.3    Yu, R.T.4    Ham, J.5    Kang, H.6    Evans, R.M.7
  • 37
    • 0034868440 scopus 로고    scopus 로고
    • A modified choline-deficient, ethionine-supplemented diet protocol effectively induces oval cells in mouse liver
    • Akhurst,B., Croager,E.J., Farley-Roche,C.A., Ong,J.K., Dumble,M.L., Knight,B. and Yeoh,G.C. (2001) A modified choline-deficient, ethionine-supplemented diet protocol effectively induces oval cells in mouse liver. Hepatology, 34, 519-522.
    • (2001) Hepatology , vol.34 , pp. 519-522
    • Akhurst, B.1    Croager, E.J.2    Farley-Roche, C.A.3    Ong, J.K.4    Dumble, M.L.5    Knight, B.6    Yeoh, G.C.7
  • 38
    • 9644262296 scopus 로고    scopus 로고
    • Direct effects of interleukin-6 on liver progenitor oval cells in culture
    • Matthews,V.B., Klinken,E. and Yeoh,G.C. (2004) Direct effects of interleukin-6 on liver progenitor oval cells in culture. Wound Repair Regen., 12, 650-656.
    • (2004) Wound Repair Regen. , vol.12 , pp. 650-656
    • Matthews, V.B.1    Klinken, E.2    Yeoh, G.C.3
  • 39
    • 18844447266 scopus 로고    scopus 로고
    • Oncostatin M induces an acute phase response, but does not modulate the growth or maturation-status of liver progenitor (oval) cells in culture
    • Matthews,V.B., Knight,B., Tirnitz-Parker,J.E.E., Boon,J., Olynyk,J.K. and Yeoh,G.C. (2005) Oncostatin M induces an acute phase response, but does not modulate the growth or maturation-status of liver progenitor (oval) cells in culture. Exp. Cell Res., 306, 252-263.
    • (2005) Exp. Cell Res. , vol.306 , pp. 252-263
    • Matthews, V.B.1    Knight, B.2    Tirnitz-Parker, J.E.E.3    Boon, J.4    Olynyk, J.K.5    Yeoh, G.C.6
  • 40
    • 0022445670 scopus 로고
    • Rapid colorimetric assay for cell growth and survival. Modifications to the tetrazolium dye procedure giving improved sensitivity and reliability
    • Denizot,F. and Lang,R. (1986) Rapid colorimetric assay for cell growth and survival. Modifications to the tetrazolium dye procedure giving improved sensitivity and reliability. J. Immunol. Methods, 89, 271-277.
    • (1986) J. Immunol. Methods , vol.89 , pp. 271-277
    • Denizot, F.1    Lang, R.2
  • 41
    • 77049156222 scopus 로고
    • A modification of Masson's trichrome stain which differentiates in colour between striated and smooth muscle
    • Towers,B. (1953) A modification of Masson's trichrome stain which differentiates in colour between striated and smooth muscle. J. Physiol., 119, 23P-24P.
    • (1953) J. Physiol. , vol.119
    • Towers, B.1
  • 42
    • 16644375655 scopus 로고    scopus 로고
    • CD14-positive hepatic monocytes/macrophages increase in hereditary hemochromatosis
    • Leicester,K.L., Olynyk,J.K., Brunt,E.M., Britton,R.S. and Bacon,B.R. (2004) CD14-positive hepatic monocytes/macrophages increase in hereditary hemochromatosis. Liver Int., 24, 446-451.
    • (2004) Liver Int. , vol.24 , pp. 446-451
    • Leicester, K.L.1    Olynyk, J.K.2    Brunt, E.M.3    Britton, R.S.4    Bacon, B.R.5
  • 43
    • 2342455049 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma is expressed in airways and inhibits features of airway remodeling in a mouse asthma model
    • Honda,K., Marquillies,P., Capron,M. and Dombrowicz,D. (2004) Peroxisome proliferator-activated receptor gamma is expressed in airways and inhibits features of airway remodeling in a mouse asthma model. J. Allergy Clin. Immunol., 113, 882-888.
    • (2004) J. Allergy Clin. Immunol. , vol.113 , pp. 882-888
    • Honda, K.1    Marquillies, P.2    Capron, M.3    Dombrowicz, D.4
  • 44
    • 5044242957 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-gamma induces regression of endometrial explants in a rat model of endometriosis
    • Lebovic,D.I., Kir,M. and Casey,C.L. (2004) Peroxisome proliferator-activated receptor-gamma induces regression of endometrial explants in a rat model of endometriosis. Fertil. Steril., 81 (Suppl. 3), 1008-1013.
    • (2004) Fertil. Steril. , vol.81 , Issue.SUPPL. 3 , pp. 1008-1013
    • Lebovic, D.I.1    Kir, M.2    Casey, C.L.3
  • 45
    • 1942470331 scopus 로고    scopus 로고
    • Activation of nuclear hormone receptor peroxisome proliferator-activated receptor-delta accelerates intestinal adenoma growth
    • Gupta,R.A., Wang,D., Katkuri,S., Wang,H., Dey,S.K. and DuBois,R.N. (2004) Activation of nuclear hormone receptor peroxisome proliferator-activated receptor-delta accelerates intestinal adenoma growth. Nature Med., 10, 245-247.
    • (2004) Nature Med. , vol.10 , pp. 245-247
    • Gupta, R.A.1    Wang, D.2    Katkuri, S.3    Wang, H.4    Dey, S.K.5    DuBois, R.N.6
  • 46
    • 0030835678 scopus 로고    scopus 로고
    • The organization, promoter analysis, and expression of the human PPARgamma gene
    • Fajas,L., Auboeuf,D., Raspe,E. et al. (1997) The organization, promoter analysis, and expression of the human PPARgamma gene. J. Biol. Chem., 272, 18779-18789.
    • (1997) J. Biol. Chem. , vol.272 , pp. 18779-18789
    • Fajas, L.1    Auboeuf, D.2    Raspe, E.3
  • 48
    • 0033428565 scopus 로고    scopus 로고
    • Suppression of apoptosis and induction of DNA synthesis in vitro by the phthalate plasticizers monoethylhexylphthalate (MEHP) and diisononylphthalate (DINP): A comparison of rat and human hepatocytes in vitro
    • Hasmall,S.C., James,N.H., Macdonald,N., West,D., Chevalier,S., Cosulich,S.C. and Roberts,R.A. (1999) Suppression of apoptosis and induction of DNA synthesis in vitro by the phthalate plasticizers monoethylhexylphthalate (MEHP) and diisononylphthalate (DINP): A comparison of rat and human hepatocytes in vitro. Arch. Toxicol., 73, 451-456.
    • (1999) Arch. Toxicol. , vol.73 , pp. 451-456
    • Hasmall, S.C.1    James, N.H.2    Macdonald, N.3    West, D.4    Chevalier, S.5    Cosulich, S.C.6    Roberts, R.A.7
  • 49
    • 0033200395 scopus 로고    scopus 로고
    • The extracellular signal-regulated kinase pathway contributes to mitogenic and antiapoptotic effects of peroxisome proliferators in vitro
    • Mounho,B.J. and Thrall,B.D. (1999) The extracellular signal-regulated kinase pathway contributes to mitogenic and antiapoptotic effects of peroxisome proliferators in vitro. Toxicol. Appl. Pharmacol., 159, 125-133.
    • (1999) Toxicol. Appl. Pharmacol. , vol.159 , pp. 125-133
    • Mounho, B.J.1    Thrall, B.D.2
  • 50
    • 0031658358 scopus 로고    scopus 로고
    • The coordinate regulation of DNA synthesis and suppression of apoptosis is differentially regulated by the liver growth agents, phenobarbital and methylclofenapate
    • Plant,N.J., Horley,N.J., Dickins,M., Hasmall,S., Elcombe,C.R. and Bell,D.R. (1998) The coordinate regulation of DNA synthesis and suppression of apoptosis is differentially regulated by the liver growth agents, phenobarbital and methylclofenapate. Carcinogenesis, 19, 1521-1527.
    • (1998) Carcinogenesis , vol.19 , pp. 1521-1527
    • Plant, N.J.1    Horley, N.J.2    Dickins, M.3    Hasmall, S.4    Elcombe, C.R.5    Bell, D.R.6
  • 51
    • 0033965526 scopus 로고    scopus 로고
    • Differentiation of rat oval cells after activation of peroxisome proliferator-activated receptor alpha43
    • Kaplanski,C., Pauley,C.J., Griffiths,T.G., Kawabata,T.T. and Ledwith,B.J. (2000) Differentiation of rat oval cells after activation of peroxisome proliferator-activated receptor alpha43. Cancer Res., 60, 580-587.
    • (2000) Cancer Res. , vol.60 , pp. 580-587
    • Kaplanski, C.1    Pauley, C.J.2    Griffiths, T.G.3    Kawabata, T.T.4    Ledwith, B.J.5
  • 52
    • 2542454565 scopus 로고    scopus 로고
    • Be fit or be sick: Peroxisome proliferator-activated receptors are down the road
    • Desvergne,B., Michalik,L. and Wahli,W. (2004) Be fit or be sick: peroxisome proliferator-activated receptors are down the road. Mol. Endocrinol., 18, 1321-1332.
    • (2004) Mol. Endocrinol. , vol.18 , pp. 1321-1332
    • Desvergne, B.1    Michalik, L.2    Wahli, W.3
  • 53
    • 2442425421 scopus 로고    scopus 로고
    • Rosiglitazone, a ligand of the peroxisome proliferator-activated receptor-gamma, reduces acute pancreatitis induced by cerulein
    • Cuzzocrea,S., Pisano,B., Dugo,L. et al. (2004) Rosiglitazone, a ligand of the peroxisome proliferator-activated receptor-gamma, reduces acute pancreatitis induced by cerulein. Intensive Care Med., 30, 951-956.
    • (2004) Intensive Care Med. , vol.30 , pp. 951-956
    • Cuzzocrea, S.1    Pisano, B.2    Dugo, L.3
  • 57
    • 1842716887 scopus 로고    scopus 로고
    • Effects of PPARg agonist pioglitazone on rat hepatic fibrosis
    • Yuan,G.J., Zhang,M.L. and Gong,Z.J. (2004) Effects of PPARg agonist pioglitazone on rat hepatic fibrosis. World J. Gastroenterol., 10, 1047-1051.
    • (2004) World J. Gastroenterol. , vol.10 , pp. 1047-1051
    • Yuan, G.J.1    Zhang, M.L.2    Gong, Z.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.