Antioxidant activities and xanthine oxidase inhibitory effects of extracts and main polyphenolic compounds obtained from geranium sibiricum L.

Journal of Agricultural and Food Chemistry

Volumn 58, Issue 8, 2010, Pages 4737-4743

  Wu, Nan ^a   Zu, Yuangang ^a   Fu, Yujie ^a   Kong, Yu ^a   Zhao, Jintong ^a   Li, Xiaojuan ^a   Li, Ji ^a   Wink, Michael ^b   Efferth, Thomas ^c  

^a NORTHEAST FORESTRY UNIVERSITY   (China)

^b UNIVERSITY OF HEIDELBERG   (Germany)

^c JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

Antioxidant activity; Geranium sibiricum L.; Polyphenolic compounds; Xanthine oxidase

Indexed keywords

ANTIOXIDANT; ENZYME INHIBITOR; FLAVONOID; PHENOL DERIVATIVE; PLANT EXTRACT; POLYPHENOLS; XANTHINE OXIDASE;

ARTICLE; CHEMISTRY; DRUG ANTAGONISM; GERANIUM; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

ANTIOXIDANTS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ENZYME INHIBITORS; FLAVONOIDS; GERANIUM; PHENOLS; PLANT EXTRACTS; XANTHINE OXIDASE;

GERANIUM SIBIRICUM;

EID: 77951276679     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf904593n     Document Type: Article

References (34)

1. Shim, J. U.; Oh, P. S.; Lim, K. T. Anti-inflammatory activity of ethanol extract from Geranium sibiricum Linne J. Ethnopharmacol. 2009, 126, 90-95
2. Serkedjieva, J.; Ivancheva, S. Antiherpes virus activity of extracts from the medicinal plant Geranium sanguineum L J. Ethnopharmacol. 1999, 64, 59-68
3. Şöhretoǧlu, D.; Ekizoǧlu, M.; Özalp, M.; Sakar, M. K. Free radical scavenging and antimicrobial activities of some Geranium species H. U. J. Fac. Pharm. 2008, 28, 115-124
4. Nikolaevich, G.; Jurievna, E.; Alexeevna, O.; Ivanovna, N.; Mikhailovich, J.; Romanovna, E.; Alexandrovich, G.; Ivanovich, V.; Eduardovna, E.; Ivanovna, R. Substance in the form of an aqueous extract of vegetal raw material for treating oncological diseases and method for producing the same. European Patent Application. WO 98/24458 (11.06.1998 Gazette 1998/23).
5. Hammond, G. B.; Fernández, I. D.; Villegas, L. F.; Vaisberg, A. J. A survey of traditional medicinal plants from the Callejón de Huaylas, Department of Ancash, Perú J. Ethnopharmacol. 1998, 61, 17-30
6. Yin, H. B. Pharmacognosy research of Herba Geranii in the northeast of China. Ph.D. Thesis, Liaoning University of Traditional Chinese Medicine, August, 1997.
7. Lee, S. R.; Yoon, E. S.; Shin, S. C.; Lee, S. C. Screening for antitumor efficacy from the wild plants in Korea (II) J. Orient. Bot. Resour. 1993, 6, 25-32
8. Shim, J. U.; Lim, K. T. Anti-oxidative and anti-proliferative character of glycoprotein isolated from Geranium sibiricum Linne in Chang liver cells Environ. Toxicol. Pharmacol. 2008, 26, 320-324
9. Cheng, J. T.; Lin, T. C.; Hsu, F. L. Antihypertensive effect of corilagin in the rat Can. J. Physiol. Pharmacol. 1995, 73, 1425-1429
10. Kinoshita, S.; Inoue, Y.; Nakama, S.; Ichiba, T.; Aniya, Y. Antioxidant and hepatoprotective actions of medicinal herb, Terminalia catappa L. from Okinawa Island and its tannin corilagin Phytomedicine 2007, 14, 755-762
11. Uozaki, M.; Yamasaki, H.; Katsuyama, Y.; Higuchi, M.; Higuti, T.; Koyama, A. H. Antiviral effect of octyl gallate against DNA and RNA viruses Antiviral Res. 2007, 73, 85-91
12. Sokmen, M.; Angelova, M.; Krumova, E.; Pashova, S.; Ivancheva, S.; Sokmen, A.; Serkedjieva, J. In vitro antioxidant activity of polyphenol extracts with antiviral properties from Geranium sanguineum L Life Sci. 2005, 76, 2981-2993
13. Simonian, N. A.; Coyle, J. T. Oxidative stress in neurodegenerative diseases Annu. Rev. Pharmacol. Toxicol. 1996, 36, 83-106
14. Hatano, T.; Edamatsu, R.; Hiramatsu, M.; Mori, A.; Fujita, Y.; Yoshida, T.; Okuda, T. Effects of interaction of tannins with co-existing substances. VI: Effects of tannins and related polyphenols on superoxide anion radical, and on 1,1-diphenyl-2-picrylhydrazyl radical Chem. Pharm. Bull. 1989, 37, 2016-2021
15. Halliwell, B. Reactive oxygen species in living systems: Source, biochemistry, and role in human disease Am. J. Med. 1991, 91, S14-S22
16. Karagözler, A. A.; Erdag, B.; Emek, Y. C.; Uygun, D. A. Antioxidant activity and proline content of leaf extracts from Dorystoechas hastate Food Chem. 2008, 111, 400-407
17. Tabata, H.; Katsube, T.; Tsuma, T.; Ohta, Y.; Imawaka, N.; Utsumi, T. Isolation and evaluation of the radical-scavenging activity of the antioxidants in the leaves of an edible plant, Mallotus japonicus Food Chem. 2008, 109, 64-71
18. Wang, H.; Provan, G. J.; Helliwell, K. Determination of hamamelitannin, catechins and gallic acid in witch hazel bark, twig and leaf by HPLC J. Pharm. Biomed. 2003, 33, 539-544
19. Oktay, M.; Gulcin, I.; Kufrevioglu, O. I. Determination of in vitro antioxidant activity of fennel (Foeniculum vulgare) seed extracts Lebens.-Wiss. Technol. 2003, 36, 263-271
20. Wang, Z. H.; Hsu, C. C.; Yin, M. C. Antioxidative characteristics of aqueous and ethanol extracts of glossy privet fruit Food Chem. 2009, 112, 914-918
21. Gullcin, I. Antioxidant activity of caffeic acid (3,4-dihydroxycinnamic acid) Toxicology 2006, 217, 213-220
22. Huang, D.; Ou, B.; Prior, R. L. The chemistry behind antioxidant capacity assays - Reviews J. Agric. Food Chem. 2005, 53, 1841-1856
23. Kamiloǧlu, Ö.; Ercisli, S.; Şengül, M.; Toplu, C.; Serçe, S. Total phenolics and antioxidant activity of jujube (Zizyphus jujube Mill.) genotypes selected from Turkey Afr. J. Biotechnol. 2009, 8, 303-307
24. Kaur, C.; Kapoor, H. C. Anti-oxidant activity and total phenolic content of some Asian vegetables Int. J. Food Sci. Technol. 2002, 37, 153-161 (Pubitemid 36840533)
25. Miliauskas, G.; Venskutonisa, P. R.; Beek, T. A. Screening of radical scavenging activity of some medicinal and aromatic plant extracts Food Chem. 2004, 85, 231-237
26. Halvorsen, B. L.; Holte, K.; Myhrstad, M. C. W.; Barikmo, I.; Hvattum, E.; Remberg, S. F; Wold, A. B.; Haffner, K.; Baugerod, H.; Andersen, L. F.; Jacobs, D. R.; Blomhoff, R. A systematic screening of total antioxidants in dietary plants J. Nutr. 2002, 132, 461-471
27. Albayrak, S.; Aksoy, A.; Sagdic, O.; Hamzaoglu, E. Compositions, antioxidant and antimicrobial activities of Helichrysum (Asteraceae) species collected from Turkey Food Chem. 2010, 119, 114-122
28. Parejo, I.; Viladomat, F.; Bastida, J.; Rosas-Romero, A.; Saavedra, G.; Murcia, M. A.; Jiménez, A. M.; Codina, C. Investigation of Bolivian plant extracts for their radical scavenging activity and antioxidant activity Life Sci. 2003, 73, 1667-1681
29. Hatano, T.; Yasuhara, T.; Yoshihara, R.; Agata, I.; Noro, T.; Okuda, T. Effects of interaction of tannins with co-existing substances. VII: Inhibitory effects of tannins and related polyphenols on xanthine oxidase Chem. Pharm. Bull. 1990, 38, 1224-1229
30. Sabuncuoglu, S.; Sohretoglu, D.; Koray Sakar, M.; Ozgunes, H. Antioxidant activity of polyphenolic compounds and extracts from Geranium purpureum Toxicol. Lett. 2008, 180S, S32-S246
31. Hagerman, A. E.; Riedl, K. M.; Jones, G. A.; Sovik, K. N.; Ritchard, N. T.; Hartzfeld, P. W.; Riechel, T. L. High molecular weight plant polyphenolics (tannins) as biological antioxidants J. Agric. Food Chem. 1998, 46, 1887-1892
32. Lin, J. K.; Chen, P. C.; Ho, C. T.; Lin-Shiau, S. Y. Inhibition of xanthine oxidase and suppression of intracellular reactive oxygen species in HL-60 cells by theaflavin-3,3′-digallate, (-)-epigallocatechin-3-gallate, and propyl Gallate J. Agric. Food Chem. 2000, 48, 2736-2743
33. Chang, W. S.; Lee, Y. J.; Lu, F. J.; Chiang, H. C. Inhibitory effects of flavonoids on xanthine oxidase Anticancer Res. 1993, 13, 2165-2170
34. Nagno, A.; Seki, M.; Kobayachi, H. Inhibition of xanthine oxidase by flavonoids Biosci., Biotechnol., Biochem. 1999, 63, 1787-1790