-
1
-
-
6944250259
-
Role of resveratrol in prevention and therapy of cancer: Preclinical and clinical studies
-
Aggarwal B.B., Bhardwaj A., Aggarwal RS.i wsp.: Role of resveratrol in prevention and therapy of cancer: preclinical and clinical studies. Anticancer Res., 2004. 24 (5A), 2783-2840.
-
(2004)
Anticancer Res.
, vol.24
, Issue.5 A
, pp. 2783-2840
-
-
Aggarwal, B.B.1
Bhardwaj, A.2
Aggarwal, R.S.3
-
4
-
-
33644875954
-
Neuronal protection by sirtuins in Alzheimer's disease
-
Anekonda T.S., Reddy P.H.: Neuronal protection by sirtuins in Alzheimer's disease. J. Neurochem., 2006, 96 (2), 305-313.
-
(2006)
J. Neurochem.
, vol.96
, Issue.2
, pp. 305-313
-
-
Anekonda, T.S.1
Reddy, P.H.2
-
5
-
-
1642297558
-
Structural basis for the mechanism and regulation of Sir2 enzymes
-
Avalos J.L., Boeke J.D., Wolberger C.: Structural basis for the mechanism and regulation of Sir2 enzymes. Mol. Cell, 2004, 12, 13 (5), 639-648.
-
(2004)
Mol. Cell
, vol.12-13
, Issue.5
, pp. 639-648
-
-
Avalos, J.L.1
Boeke, J.D.2
Wolberger, C.3
-
6
-
-
20444444649
-
Mechanism of human SIRT1 activation by resveratrol
-
Borra M.T., Smith B.C., Denu J.M.: Mechanism of human SIRT1 activation by resveratrol. J. Biol. Chem., 2005, 29, 280 (17), 17187-17195.
-
(2005)
J. Biol. Chem.
, vol.29-280
, Issue.17
, pp. 17187-17195
-
-
Borra, M.T.1
Smith, B.C.2
Denu, J.M.3
-
7
-
-
42949156843
-
P53 Activation: A case against Sir
-
Brooks CL., Gu W.: p53 Activation: a case against Sir. Cancer Cell, 2008, 13 (5), 377-378.
-
(2008)
Cancer Cell
, vol.13
, Issue.5
, pp. 377-378
-
-
Brooks, C.L.1
Gu, W.2
-
8
-
-
41949118209
-
Sirtuins: Novel targets for metabolic disease
-
Elliott P. J., Jirousek M.: Sirtuins: novel targets for metabolic disease. Curr. Opin. Investig. Drugs, 2008, 9 (4), 371-378.
-
(2008)
Curr. Opin. Investig. Drugs
, vol.9
, Issue.4
, pp. 371-378
-
-
Elliott, P.J.1
Jirousek, M.2
-
9
-
-
54849425547
-
Specific SIRTI activation mimics low energy levels and protects against diet-induced metabolic disorders by enhancing fat oxidation
-
Feige J.N., tagouge M., Canto C i wsp.: Specific SIRTI activation mimics low energy levels and protects against diet-induced metabolic disorders by enhancing fat oxidation. Cell Metab., 2008, 8 (5), 347-358.
-
(2008)
Cell Metab.
, vol.8
, Issue.5
, pp. 347-358
-
-
Feige, J.N.1
Tagouge, M.2
Canto, C.3
-
10
-
-
44849096876
-
The SIRT1 deacetylase suppresses intestinal tumorigenesis and colon cancer growth
-
Firestein R., Blander G., Michan S. i wsp.: The SIRT1 deacetylase suppresses intestinal tumorigenesis and colon cancer growth. PLoS One, 2008, 3 (4), e2020.
-
(2008)
PLoS One
, vol.3
, Issue.4
-
-
Firestein, R.1
Blander, G.2
Michan, S.3
-
11
-
-
34548570794
-
Linking SIRT2 to Paridnson's disease
-
Garske A.L, Smith B.C., Denu J.M.: Linking SIRT2 to Paridnson's disease. ACS Chem. Biol., 2007, 17, 2 (8), 529-532.
-
(2007)
ACS Chem. Biol.
, vol.17
, Issue.2-8
, pp. 529-532
-
-
Garske, A.L.1
Smith, B.C.2
Denu, J.M.3
-
12
-
-
0142243190
-
Relationship between mechanisms, bioavailibility, and preclinical chemopreventive efficacy of resveratrol: A conundrum
-
Gescher A.J., Steward W.P.: Relationship between mechanisms, bioavailibility, and preclinical chemopreventive efficacy of resveratrol: a conundrum. Cancer Epidemiol. Biomarkers Prev., 2003, 12 (10), 953-957.
-
(2003)
Cancer Epidemiol. Biomarkers Prev.
, vol.12
, Issue.10
, pp. 953-957
-
-
Gescher, A.J.1
Steward, W.P.2
-
13
-
-
13944253348
-
Calorie restriction - The SIR2 connection
-
Guarente L., Picard F.: Calorie restriction - the SIR2 connection. Cell, 2005, 25, 120 (4), 473-4.82.
-
(2005)
Cell
, vol.25-120
, Issue.4
, pp. 473-482
-
-
Guarente, L.1
Picard, F.2
-
14
-
-
33646254136
-
Antitumor activity of a smallmolecule inhibitor of human silent information regulator 2 enzymes
-
Heltweg B., Gatbonton T., Schuler AD. i wsp.: Antitumor activity of a smallmolecule inhibitor of human silent information regulator 2 enzymes. Cancer Res., 2006, 15, 66 (8), 4368-4377.
-
(2006)
Cancer Res.
, vol.15-66
, Issue.8
, pp. 4368-4377
-
-
Heltweg, B.1
Gatbonton, T.2
Schuler, A.D.3
-
15
-
-
34447308268
-
SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis
-
Kim D., Nguyen M.D., Dobbin M.M. i wsp.: SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis. EMBO J., 2007, 11, 26 (13), 3169-3179.
-
(2007)
EMBO J.
, vol.11-26
, Issue.13
, pp. 3169-3179
-
-
Kim, D.1
Nguyen, M.D.2
Dobbin, M.M.3
-
16
-
-
40149093701
-
Human immunodeficiency vims type 1 Tat protein inhibits the SIRT1 deacetylase and induces T cell hyper activation
-
Kwon H.S., Brent M.M., Getachew R. i wsp.: Human immunodeficiency vims type 1 Tat protein inhibits the SIRT1 deacetylase and induces T cell hyper activation. Cell Host Microbe, 2008. 13, 3 (3), 158-167.
-
(2008)
Cell Host Microbe
, vol.13
, Issue.3
, pp. 158-167
-
-
Kwon, H.S.1
Brent, M.M.2
Getachew, R.3
-
17
-
-
33845399894
-
Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha
-
Lagouge M., Argmann C., Gerhart-Hines Z. i wsp.: Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha. Cell, 2006, 15, 127 (6), 1109-1122.
-
(2006)
Cell
, vol.15-127
, Issue.6
, pp. 1109-1122
-
-
Lagouge, M.1
Argmann, C.2
Gerhart-Hines, Z.3
-
18
-
-
60149091562
-
Salermide, a Sirtuin inhibitor with a strong cancer-specific pmapoptotic effect
-
Lara E., Mai A., Calvanese V. i wsp.: Salermide, a Sirtuin inhibitor with a strong cancer-specific pmapoptotic effect. Oncogene, 2009, 12, 28 (6), 781-791.
-
(2009)
Oncogene
, vol.12-28
, Issue.6
, pp. 781-791
-
-
Lara, E.1
Mai, A.2
Calvanese, V.3
-
19
-
-
0032514633
-
Memory-enhancing effects of secreted forms of the beta-amyloid precursor protein in normal and amnestic mice
-
Meziane H., Dodart J.C, Mathis C i wsp.: Memory-enhancing effects of secreted forms of the beta-amyloid precursor protein in normal and amnestic mice. Proc. Natl. Acad. Sci. USA, 1998,13, 95 (21), 12683-12688.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.13-95
, Issue.21
, pp. 12683-12688
-
-
Meziane, H.1
Dodart, J.C.2
Mathis, C.3
-
20
-
-
20144372893
-
SIRT1 regulates HIV transcription via Tat deacetylation
-
Pagans S., Pedal A., North B.J. i wsp.: SIRT1 regulates HIV transcription via Tat deacetylation. PLoS Biol., 2005, 3 (2), e41.
-
(2005)
PLoS Biol.
, vol.3
, Issue.2
-
-
Pagans, S.1
Pedal, A.2
North, B.J.3
-
21
-
-
47849088748
-
Emerging roles of SIRTI in vascular endothelial homeostasis
-
Potente M., Dimmeler S.: Emerging roles of SIRTI in vascular endothelial homeostasis. Cell Cycle, 2008, 15, 7 (14), 2117-2122.
-
(2008)
Cell Cycle
, vol.15
, Issue.7-14
, pp. 2117-2122
-
-
Potente, M.1
Dimmeler, S.2
-
22
-
-
33746824192
-
Neuronal SIRT1 activation as a novel mechanism underlying the prevention of Alzheimer disease amyloid neuropathology by calorie restriction
-
Qin W., Yang T., Ho L. i wsp.: Neuronal SIRT1 activation as a novel mechanism underlying the prevention of Alzheimer disease amyloid neuropathology by calorie restriction. J. Biol. Chem., 2006, 4, 281 (31), 21745-21754.
-
(2006)
J. Biol. Chem.
, vol.4-281
, Issue.31
, pp. 21745-21754
-
-
Qin, W.1
Yang, T.2
Ho, L.3
-
23
-
-
33745203038
-
The biochemistry of sirtuins
-
Sauve A.A., Wolberger C, Schramm V.L. i wsp.: The biochemistry of sirtuins. Annu. Rev. Biochem., 2006, 75, 435-465.
-
(2006)
Annu. Rev. Biochem.
, vol.75
, pp. 435-465
-
-
Sauve, A.A.1
Wolberger, C.2
Schramm, V.L.3
-
24
-
-
38649123072
-
Conserved metabolic regulatory functions of sirtuins
-
Schwer B., Verdin E.: Conserved metabolic regulatory functions of sirtuins. Cell Metab., 2008, 7 (2), 104-112.
-
(2008)
Cell Metab.
, vol.7
, Issue.2
, pp. 104-112
-
-
Schwer, B.1
Verdin, E.2
-
25
-
-
63549094179
-
Small molecule activators of SIRT1 replicate signaling pathways triggered by calorie restriction in vivo
-
Smith J.J., Kenney .D. Gagne D.J. i wsp.: Small molecule activators of SIRT1 replicate signaling pathways triggered by calorie restriction in vivo. BMC Syst. Biol., 2009, 3, 31.
-
(2009)
BMC Syst. Biol.
, vol.3
, pp. 31
-
-
Smith, J.J.1
Kenney, D.2
Gagne, D.J.3
-
26
-
-
33645221885
-
Inhibition of SIRT1 catalytic activity increases p53 acetylation but does not alter cell survival following DNA damage
-
Solomon J.M., Pasupuleti R., Xu L. i wsp.: Inhibition of SIRT1 catalytic activity increases p53 acetylation but does not alter cell survival following DNA damage. Mol. Cell Biol., 2006. 26 (1), 28-38.
-
(2006)
Mol. Cell Biol.
, vol.26
, Issue.1
, pp. 28-38
-
-
Solomon, J.M.1
Pasupuleti, R.2
Xu, L.3
-
27
-
-
58149140055
-
Biological and potential therapeutic roles of sirtuin deacetylases
-
Taylor D.M., Maxwell M.M., Luthi-Carter R. I wsp.: Biological and potential therapeutic roles of sirtuin deacetylases. Cell MoI. Life Sd., 2008, 65 (24), 4000-4018.
-
(2008)
Cell MoI. Life Sd.
, vol.65
, Issue.24
, pp. 4000-4018
-
-
Taylor, D.M.1
Maxwell, M.M.2
Luthi-Carter, R.3
-
28
-
-
41449083867
-
Sirt7 increases stress resistance of cardiomyocytes and prevents apoptosis and inflammatory cardiomyopathy in mice
-
Vakhrusheva O., Smolka C., Gajawada P. i wsp.: Sirt7 increases stress resistance of cardiomyocytes and prevents apoptosis and inflammatory cardiomyopathy in mice. Circ. Res., 2008, 28, 102 (6), 703-710.
-
(2008)
Circ. Res.
, vol.28-102
, Issue.6
, pp. 703-710
-
-
Vakhrusheva, O.1
Smolka, C.2
Gajawada, P.3
-
29
-
-
34547413569
-
Sirtuin functions in health and disease
-
Yamamoto H., Schoonjans K., Auwerx J.: Sirtuin functions in health and disease. Mol. Endocrinol., 2007, 21 (8), 1745-1755.
-
(2007)
Mol. Endocrinol.
, vol.21
, Issue.8
, pp. 1745-1755
-
-
Yamamoto, H.1
Schoonjans, K.2
Auwerx, J.3
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