-
1
-
-
0035909925
-
Interleukin-12 receptor/STAT4 signaling is required for the development of autoimmune myocarditis in mice by an interferon-gamma-independent pathway
-
Afanasyeva M., Wang Y., Kaya Z., Stafford E.A., Dohmen K.M., Sadighi Akha A.A., Rose N.R. Interleukin-12 receptor/STAT4 signaling is required for the development of autoimmune myocarditis in mice by an interferon-gamma-independent pathway. Circulation 2001, 104(25):3145-3151.
-
(2001)
Circulation
, vol.104
, Issue.25
, pp. 3145-3151
-
-
Afanasyeva, M.1
Wang, Y.2
Kaya, Z.3
Stafford, E.A.4
Dohmen, K.M.5
Sadighi Akha, A.A.6
Rose, N.R.7
-
2
-
-
13444269543
-
Haploview: analysis and visualization of LD and haplotype maps
-
Barrett J.C., Fry B., Maller J., Daly M.J. Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics 2005, 21(2):263-265.
-
(2005)
Bioinformatics
, vol.21
, Issue.2
, pp. 263-265
-
-
Barrett, J.C.1
Fry, B.2
Maller, J.3
Daly, M.J.4
-
3
-
-
48349136889
-
Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease
-
Barrett J.C., Hansoul S., Nicolae D.L., Cho J.H., Duerr R.H., Rioux J.D., Brant S.R., Silverberg M.S., Taylor K.D., Barmada M.M., Bitton A., Dassopoulos T., Datta L.W., Green T., Griffiths A.M., Kistner E.O., Murtha M.T., Regueiro M.D., Rotter J.I., Schumm L.P., Steinhart A.H., Targan S.R., Xavier R.J., Libioulle C., Sandor C., Lathrop M., Belaiche J., Dewit O., Gut I., Heath S., Laukens D., Mni M., Rutgeerts P., Van Gossum A., Zelenika D., Franchimont D., Hugot J.P., de Vos M., Vermeire S., Louis E., Cardon L.R., Anderson C.A., Drummond H., Nimmo E., Ahmad T., Prescott N.J., Onnie C.M., Fisher S.A., Marchini J., Ghori J., Bumpstead S., Gwilliam R., Tremelling M., Deloukas P., Mansfield J., Jewell D., Satsangi J., Mathew C.G., Parkes M., Georges M., Daly M.J. Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease. Nat. Genet. 2008, 40(8):955-962.
-
(2008)
Nat. Genet.
, vol.40
, Issue.8
, pp. 955-962
-
-
Barrett, J.C.1
Hansoul, S.2
Nicolae, D.L.3
Cho, J.H.4
Duerr, R.H.5
Rioux, J.D.6
Brant, S.R.7
Silverberg, M.S.8
Taylor, K.D.9
Barmada, M.M.10
Bitton, A.11
Dassopoulos, T.12
Datta, L.W.13
Green, T.14
Griffiths, A.M.15
Kistner, E.O.16
Murtha, M.T.17
Regueiro, M.D.18
Rotter, J.I.19
Schumm, L.P.20
Steinhart, A.H.21
Targan, S.R.22
Xavier, R.J.23
Libioulle, C.24
Sandor, C.25
Lathrop, M.26
Belaiche, J.27
Dewit, O.28
Gut, I.29
Heath, S.30
Laukens, D.31
Mni, M.32
Rutgeerts, P.33
Van Gossum, A.34
Zelenika, D.35
Franchimont, D.36
Hugot, J.P.37
de Vos, M.38
Vermeire, S.39
Louis, E.40
Cardon, L.R.41
Anderson, C.A.42
Drummond, H.43
Nimmo, E.44
Ahmad, T.45
Prescott, N.J.46
Onnie, C.M.47
Fisher, S.A.48
Marchini, J.49
Ghori, J.50
Bumpstead, S.51
Gwilliam, R.52
Tremelling, M.53
Deloukas, P.54
Mansfield, J.55
Jewell, D.56
Satsangi, J.57
Mathew, C.G.58
Parkes, M.59
Georges, M.60
Daly, M.J.61
more..
-
4
-
-
0032544004
-
Clustering of non-major histocompatibility complex susceptibility candidate loci in human autoimmune diseases
-
Becker K.G., Simon R.M., Bailey-Wilson J.E., Freidlin B., Biddison W.E., McFarland H.F., Trent J.M. Clustering of non-major histocompatibility complex susceptibility candidate loci in human autoimmune diseases. Proc. Natl. Acad. Sci. U. S. A. 1998, 95(17):9979-9984.
-
(1998)
Proc. Natl. Acad. Sci. U. S. A.
, vol.95
, Issue.17
, pp. 9979-9984
-
-
Becker, K.G.1
Simon, R.M.2
Bailey-Wilson, J.E.3
Freidlin, B.4
Biddison, W.E.5
McFarland, H.F.6
Trent, J.M.7
-
5
-
-
24144497765
-
The clustering of other chronic inflammatory diseases in inflammatory bowel disease: a population-based study
-
Bernstein C.N., Wajda A., Blanchard J.F. The clustering of other chronic inflammatory diseases in inflammatory bowel disease: a population-based study. Gastroenterology 2005, 129(3):827-836.
-
(2005)
Gastroenterology
, vol.129
, Issue.3
, pp. 827-836
-
-
Bernstein, C.N.1
Wajda, A.2
Blanchard, J.F.3
-
6
-
-
34248572345
-
T(H)-17 cells in the circle of immunity and autoimmunity
-
Bettelli E., Oukka M., Kuchroo V.K. T(H)-17 cells in the circle of immunity and autoimmunity. Nat. Immunol. 2007, 8(4):345-350.
-
(2007)
Nat. Immunol.
, vol.8
, Issue.4
, pp. 345-350
-
-
Bettelli, E.1
Oukka, M.2
Kuchroo, V.K.3
-
7
-
-
37849027930
-
Haplotypes of PADI4 susceptible to rheumatoid arthritis are also associated with ulcerative colitis in the Japanese population
-
Chen C.C., Isomoto H., Narumi Y., Sato K., Oishi Y., Kobayashi T., Yanagihara K., Mizuta Y., Kohno S., Tsukamoto K. Haplotypes of PADI4 susceptible to rheumatoid arthritis are also associated with ulcerative colitis in the Japanese population. Clin. Immunol. 2008, 126(2):165-171.
-
(2008)
Clin. Immunol.
, vol.126
, Issue.2
, pp. 165-171
-
-
Chen, C.C.1
Isomoto, H.2
Narumi, Y.3
Sato, K.4
Oishi, Y.5
Kobayashi, T.6
Yanagihara, K.7
Mizuta, Y.8
Kohno, S.9
Tsukamoto, K.10
-
8
-
-
0034789247
-
Effect of targeted disruption of STAT4 and STAT6 on the induction of experimental autoimmune encephalomyelitis
-
Chitnis T., Najafian N., Benou C., Salama A.D., Grusby M.J., Sayegh M.H., Khoury S.J. Effect of targeted disruption of STAT4 and STAT6 on the induction of experimental autoimmune encephalomyelitis. J. Clin. Invest. 2001, 108(5):739-747.
-
(2001)
J. Clin. Invest.
, vol.108
, Issue.5
, pp. 739-747
-
-
Chitnis, T.1
Najafian, N.2
Benou, C.3
Salama, A.D.4
Grusby, M.J.5
Sayegh, M.H.6
Khoury, S.J.7
-
9
-
-
0037265610
-
Haplotype structure and association to Crohn's disease of CARD15 mutations in two ethnically divergent populations
-
Croucher P.J., Mascheretti S., Hampe J., Huse K., Frenzel H., Stoll M., Lu T., Nikolaus S., Yang S.K., Krawczak M., Kim W.H., Schreiber S. Haplotype structure and association to Crohn's disease of CARD15 mutations in two ethnically divergent populations. Eur. J. Hum. Genet. 2003, 11(1):6-16.
-
(2003)
Eur. J. Hum. Genet.
, vol.11
, Issue.1
, pp. 6-16
-
-
Croucher, P.J.1
Mascheretti, S.2
Hampe, J.3
Huse, K.4
Frenzel, H.5
Stoll, M.6
Lu, T.7
Nikolaus, S.8
Yang, S.K.9
Krawczak, M.10
Kim, W.H.11
Schreiber, S.12
-
10
-
-
33845340501
-
A genome-wide association study identifies IL23R as an inflammatory bowel disease gene
-
Duerr R.H., Taylor K.D., Brant S.R., Rioux J.D., Silverberg M.S., Daly M.J., Steinhart A.H., Abraham C., Regueiro M., Griffiths A., Dassopoulos T., Bitton A., Yang H., Targan S., Datta L.W., Kistner E.O., Schumm L.P., Lee A.T., Gregersen P.K., Barmada M.M., Rotter J.I., Nicolae D.L., Cho J.H. A genome-wide association study identifies IL23R as an inflammatory bowel disease gene. Science 2006, 314(5804):1461-1463.
-
(2006)
Science
, vol.314
, Issue.5804
, pp. 1461-1463
-
-
Duerr, R.H.1
Taylor, K.D.2
Brant, S.R.3
Rioux, J.D.4
Silverberg, M.S.5
Daly, M.J.6
Steinhart, A.H.7
Abraham, C.8
Regueiro, M.9
Griffiths, A.10
Dassopoulos, T.11
Bitton, A.12
Yang, H.13
Targan, S.14
Datta, L.W.15
Kistner, E.O.16
Schumm, L.P.17
Lee, A.T.18
Gregersen, P.K.19
Barmada, M.M.20
Rotter, J.I.21
Nicolae, D.L.22
Cho, J.H.23
more..
-
11
-
-
0037105475
-
IL-4 and IL-12 regulate proteoglycan-induced arthritis through Stat-dependent mechanisms
-
Finnegan A., Grusby M.J., Kaplan C.D., O'Neill S.K., Eibel H., Koreny T., Czipri M., Mikecz K., Zhang J. IL-4 and IL-12 regulate proteoglycan-induced arthritis through Stat-dependent mechanisms. J. Immunol. 2002, 169(6):3345-3352.
-
(2002)
J. Immunol.
, vol.169
, Issue.6
, pp. 3345-3352
-
-
Finnegan, A.1
Grusby, M.J.2
Kaplan, C.D.3
O'Neill, S.K.4
Eibel, H.5
Koreny, T.6
Czipri, M.7
Mikecz, K.8
Zhang, J.9
-
12
-
-
33947732240
-
The IL-17 cytokine family
-
Gaffen S.L., Kramer J.M., Yu J.J., Shen F. The IL-17 cytokine family. Vitam. Horm. 2006, 74:255-282.
-
(2006)
Vitam. Horm.
, vol.74
, pp. 255-282
-
-
Gaffen, S.L.1
Kramer, J.M.2
Yu, J.J.3
Shen, F.4
-
13
-
-
0017138755
-
The extra-intestinal complications of Crohn's disease and ulcerative colitis: a study of 700 patients
-
Greenstein A.J., Janowitz H.D., Sachar D.B. The extra-intestinal complications of Crohn's disease and ulcerative colitis: a study of 700 patients. Medicine (Baltimore) 1976, 55(5):401-412.
-
(1976)
Medicine (Baltimore)
, vol.55
, Issue.5
, pp. 401-412
-
-
Greenstein, A.J.1
Janowitz, H.D.2
Sachar, D.B.3
-
14
-
-
33846627302
-
A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1
-
Hampe J., Franke A., Rosenstiel P., Till A., Teuber M., Huse K., Albrecht M., Mayr G., De La Vega F.M., Briggs J., Gunther S., Prescott N.J., Onnie C.M., Hasler R., Sipos B., Folsch U.R., Lengauer T., Platzer M., Mathew C.G., Krawczak M., Schreiber S. A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1. Nat. Genet. 2007, 39(2):207-211.
-
(2007)
Nat. Genet.
, vol.39
, Issue.2
, pp. 207-211
-
-
Hampe, J.1
Franke, A.2
Rosenstiel, P.3
Till, A.4
Teuber, M.5
Huse, K.6
Albrecht, M.7
Mayr, G.8
De La Vega, F.M.9
Briggs, J.10
Gunther, S.11
Prescott, N.J.12
Onnie, C.M.13
Hasler, R.14
Sipos, B.15
Folsch, U.R.16
Lengauer, T.17
Platzer, M.18
Mathew, C.G.19
Krawczak, M.20
Schreiber, S.21
more..
-
15
-
-
30344445931
-
Inflammatory bowel disease: epidemiology, pathogenesis, and therapeutic opportunities
-
Hanauer S.B. Inflammatory bowel disease: epidemiology, pathogenesis, and therapeutic opportunities. Inflamm. Bowel Dis. 2006, 12(Suppl 1):S3-S9.
-
(2006)
Inflamm. Bowel Dis.
, vol.12
, Issue.1 SUPPL.
-
-
Hanauer, S.B.1
-
16
-
-
0345422708
-
Disruption of the STAT4 signaling pathway protects from autoimmune diabetes while retaining antiviral immune competence
-
Holz A., Bot A., Coon B., Wolfe T., Grusby M.J., von Herrath M.G. Disruption of the STAT4 signaling pathway protects from autoimmune diabetes while retaining antiviral immune competence. J. Immunol. 1999, 163(10):5374-5382.
-
(1999)
J. Immunol.
, vol.163
, Issue.10
, pp. 5374-5382
-
-
Holz, A.1
Bot, A.2
Coon, B.3
Wolfe, T.4
Grusby, M.J.5
von Herrath, M.G.6
-
17
-
-
0035978651
-
Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
-
Hugot J.P., Chamaillard M., Zouali H., Lesage S., Cezard J.P., Belaiche J., Almer S., Tysk C., O'Morain C.A., Gassull M., Binder V., Finkel Y., Cortot A., Modigliani R., Laurent-Puig P., Gower-Rousseau C., Macry J., Colombel J.F., Sahbatou M., Thomas G. Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease. Nature 2001, 411(6837):599-603.
-
(2001)
Nature
, vol.411
, Issue.6837
, pp. 599-603
-
-
Hugot, J.P.1
Chamaillard, M.2
Zouali, H.3
Lesage, S.4
Cezard, J.P.5
Belaiche, J.6
Almer, S.7
Tysk, C.8
O'Morain, C.A.9
Gassull, M.10
Binder, V.11
Finkel, Y.12
Cortot, A.13
Modigliani, R.14
Laurent-Puig, P.15
Gower-Rousseau, C.16
Macry, J.17
Colombel, J.F.18
Sahbatou, M.19
Thomas, G.20
more..
-
18
-
-
0035313701
-
The Stat family in cytokine signaling
-
Ihle J.N. The Stat family in cytokine signaling. Curr. Opin. Cell Biol. 2001, 13(2):211-217.
-
(2001)
Curr. Opin. Cell Biol.
, vol.13
, Issue.2
, pp. 211-217
-
-
Ihle, J.N.1
-
19
-
-
0036306951
-
Lack of common NOD2 variants in Japanese patients with Crohn's disease
-
Inoue N., Tamura K., Kinouchi Y., Fukuda Y., Takahashi S., Ogura Y., Inohara N., Nunez G., Kishi Y., Koike Y., Shimosegawa T., Shimoyama T., Hibi T. Lack of common NOD2 variants in Japanese patients with Crohn's disease. Gastroenterology 2002, 123(1):86-91.
-
(2002)
Gastroenterology
, vol.123
, Issue.1
, pp. 86-91
-
-
Inoue, N.1
Tamura, K.2
Kinouchi, Y.3
Fukuda, Y.4
Takahashi, S.5
Ogura, Y.6
Inohara, N.7
Nunez, G.8
Kishi, Y.9
Koike, Y.10
Shimosegawa, T.11
Shimoyama, T.12
Hibi, T.13
-
20
-
-
47249119222
-
Association of STAT4 with susceptibility to rheumatoid arthritis and systemic lupus erythematosus in the Japanese population
-
Kobayashi S., Ikari K., Kaneko H., Kochi Y., Yamamoto K., Shimane K., Nakamura Y., Toyama Y., Mochizuki T., Tsukahara S., Kawaguchi Y., Terai C., Hara M., Tomatsu T., Yamanaka H., Horiuchi T., Tao K., Yasutomo K., Hamada D., Yasui N., Inoue H., Itakura M., Okamoto H., Kamatani N., Momohara S. Association of STAT4 with susceptibility to rheumatoid arthritis and systemic lupus erythematosus in the Japanese population. Arthritis Rheum. 2008, 58(7):1940-1946.
-
(2008)
Arthritis Rheum.
, vol.58
, Issue.7
, pp. 1940-1946
-
-
Kobayashi, S.1
Ikari, K.2
Kaneko, H.3
Kochi, Y.4
Yamamoto, K.5
Shimane, K.6
Nakamura, Y.7
Toyama, Y.8
Mochizuki, T.9
Tsukahara, S.10
Kawaguchi, Y.11
Terai, C.12
Hara, M.13
Tomatsu, T.14
Yamanaka, H.15
Horiuchi, T.16
Tao, K.17
Yasutomo, K.18
Hamada, D.19
Yasui, N.20
Inoue, H.21
Itakura, M.22
Okamoto, H.23
Kamatani, N.24
Momohara, S.25
more..
-
21
-
-
42549147098
-
Variant form of STAT4 is associated with primary Sjogren's syndrome
-
Korman B.D., Alba M.I., Le J.M., Alevizos I., Smith J.A., Nikolov N.P., Kastner D.L., Remmers E.F., Illei G.G. Variant form of STAT4 is associated with primary Sjogren's syndrome. Genes Immun. 2008, 9(3):267-270.
-
(2008)
Genes Immun.
, vol.9
, Issue.3
, pp. 267-270
-
-
Korman, B.D.1
Alba, M.I.2
Le, J.M.3
Alevizos, I.4
Smith, J.A.5
Nikolov, N.P.6
Kastner, D.L.7
Remmers, E.F.8
Illei, G.G.9
-
22
-
-
35348917269
-
Association of STAT4 with rheumatoid arthritis in the Korean population
-
Lee H.S., Remmers E.F., Le J.M., Kastner D.L., Bae S.C., Gregersen P.K. Association of STAT4 with rheumatoid arthritis in the Korean population. Mol. Med. 2007, 13(9-10):455-460.
-
(2007)
Mol. Med.
, vol.13
, Issue.9-10
, pp. 455-460
-
-
Lee, H.S.1
Remmers, E.F.2
Le, J.M.3
Kastner, D.L.4
Bae, S.C.5
Gregersen, P.K.6
-
23
-
-
0024810567
-
Classification of inflammatory bowel disease
-
discussion
-
Lennard-Jones J.E. Classification of inflammatory bowel disease. Scand. J. Gastroenterol. Suppl. 1989, 170(2-6):16-19. discussion.
-
(1989)
Scand. J. Gastroenterol. Suppl.
, vol.170
, Issue.2-6
, pp. 16-19
-
-
Lennard-Jones, J.E.1
-
24
-
-
34447617459
-
Involvement of dendritic cells in the pathogenesis of inflammatory bowel disease
-
Leon F., Smythies L.E., Smith P.D., Kelsall B.L. Involvement of dendritic cells in the pathogenesis of inflammatory bowel disease. Adv. Exp. Med. Biol. 2006, 579:117-132.
-
(2006)
Adv. Exp. Med. Biol.
, vol.579
, pp. 117-132
-
-
Leon, F.1
Smythies, L.E.2
Smith, P.D.3
Kelsall, B.L.4
-
25
-
-
0038235697
-
NOD2/CARD15 gene polymorphisms and Crohn's disease in the Chinese population
-
Leong R.W., Armuzzi A., Ahmad T., Wong M.L., Tse P., Jewell D.P., Sung J.J. NOD2/CARD15 gene polymorphisms and Crohn's disease in the Chinese population. Aliment. Pharmacol. Ther. 2003, 17(12):1465-1470.
-
(2003)
Aliment. Pharmacol. Ther.
, vol.17
, Issue.12
, pp. 1465-1470
-
-
Leong, R.W.1
Armuzzi, A.2
Ahmad, T.3
Wong, M.L.4
Tse, P.5
Jewell, D.P.6
Sung, J.J.7
-
26
-
-
51849120731
-
Association of the STAT4 gene with increased susceptibility for some immune-mediated diseases
-
Martinez A., Varade J., Marquez A., Cenit M.C., Espino L., Perdigones N., Santiago J.L., Fernandez-Arquero M., de la Calle H., Arroyo R., Mendoza J.L., Fernandez-Gutierrez B., de la Concha E.G., Urcelay E. Association of the STAT4 gene with increased susceptibility for some immune-mediated diseases. Arthritis Rheum. 2008, 58(9):2598-2602.
-
(2008)
Arthritis Rheum.
, vol.58
, Issue.9
, pp. 2598-2602
-
-
Martinez, A.1
Varade, J.2
Marquez, A.3
Cenit, M.C.4
Espino, L.5
Perdigones, N.6
Santiago, J.L.7
Fernandez-Arquero, M.8
de la Calle, H.9
Arroyo, R.10
Mendoza, J.L.11
Fernandez-Gutierrez, B.12
de la Concha, E.G.13
Urcelay, E.14
-
27
-
-
34247122412
-
STAT3 and STAT4 direct development of IL-17-secreting Th cells
-
Mathur A.N., Chang H.C., Zisoulis D.G., Stritesky G.L., Yu Q., O'Malley J.T., Kapur R., Levy D.E., Kansas G.S., Kaplan M.H. STAT3 and STAT4 direct development of IL-17-secreting Th cells. J. Immunol. 2007, 178(8):4901-4907.
-
(2007)
J. Immunol.
, vol.178
, Issue.8
, pp. 4901-4907
-
-
Mathur, A.N.1
Chang, H.C.2
Zisoulis, D.G.3
Stritesky, G.L.4
Yu, Q.5
O'Malley, J.T.6
Kapur, R.7
Levy, D.E.8
Kansas, G.S.9
Kaplan, M.H.10
-
28
-
-
13744249714
-
Activation pattern of signal transducers and activators of transcription (STAT) factors in inflammatory bowel diseases
-
Mudter J., Weigmann B., Bartsch B., Kiesslich R., Strand D., Galle P.R., Lehr H.A., Schmidt J., Neurath M.F. Activation pattern of signal transducers and activators of transcription (STAT) factors in inflammatory bowel diseases. Am. J. Gastroenterol. 2005, 100(1):64-72.
-
(2005)
Am. J. Gastroenterol.
, vol.100
, Issue.1
, pp. 64-72
-
-
Mudter, J.1
Weigmann, B.2
Bartsch, B.3
Kiesslich, R.4
Strand, D.5
Galle, P.R.6
Lehr, H.A.7
Schmidt, J.8
Neurath, M.F.9
-
29
-
-
65249157054
-
High-density genotyping of STAT4 reveals multiple haplotypic associations with systemic lupus erythematosus in different racial groups
-
Namjou B., Sestak A.L., Armstrong D.L., Zidovetzki R., Kelly J.A., Jacob N., Ciobanu V., Kaufman K.M., Ojwang J.O., Ziegler J., Quismorio F.P., Reiff A., Myones B.L., Guthridge J.M., Nath S.K., Bruner G.R., Mehrian-Shai R., Silverman E., Klein-Gitelman M., McCurdy D., Wagner-Weiner L., Nocton J.J., Putterman C., Bae S.C., Kim Y.J., Petri M., Reveille J.D., Vyse T.J., Gilkeson G.S., Kamen D.L., Alarcon-Riquelme M.E., Gaffney P.M., Moser K.L., Merrill J.T., Scofield R.H., James J.A., Langefeld C.D., Harley J.B., Jacob C.O. High-density genotyping of STAT4 reveals multiple haplotypic associations with systemic lupus erythematosus in different racial groups. Arthritis Rheum. 2009, 60(4):1085-1095.
-
(2009)
Arthritis Rheum.
, vol.60
, Issue.4
, pp. 1085-1095
-
-
Namjou, B.1
Sestak, A.L.2
Armstrong, D.L.3
Zidovetzki, R.4
Kelly, J.A.5
Jacob, N.6
Ciobanu, V.7
Kaufman, K.M.8
Ojwang, J.O.9
Ziegler, J.10
Quismorio, F.P.11
Reiff, A.12
Myones, B.L.13
Guthridge, J.M.14
Nath, S.K.15
Bruner, G.R.16
Mehrian-Shai, R.17
Silverman, E.18
Klein-Gitelman, M.19
McCurdy, D.20
Wagner-Weiner, L.21
Nocton, J.J.22
Putterman, C.23
Bae, S.C.24
Kim, Y.J.25
Petri, M.26
Reveille, J.D.27
Vyse, T.J.28
Gilkeson, G.S.29
Kamen, D.L.30
Alarcon-Riquelme, M.E.31
Gaffney, P.M.32
Moser, K.L.33
Merrill, J.T.34
Scofield, R.H.35
James, J.A.36
Langefeld, C.D.37
Harley, J.B.38
Jacob, C.O.39
more..
-
30
-
-
33646555786
-
Inflammatory bowel disease characteristics among African Americans, Hispanics, and non-Hispanic Whites: characterization of a large North American cohort
-
Nguyen G.C., Torres E.A., Regueiro M., Bromfield G., Bitton A., Stempak J., Dassopoulos T., Schumm P., Gregory F.J., Griffiths A.M., Hanauer S.B., Hanson J., Harris M.L., Kane S.V., Orkwis H.K., Lahaie R., Oliva-Hemker M., Pare P., Wild G.E., Rioux J.D., Yang H., Duerr R.H., Cho J.H., Steinhart A.H., Brant S.R., Silverberg M.S. Inflammatory bowel disease characteristics among African Americans, Hispanics, and non-Hispanic Whites: characterization of a large North American cohort. Am. J. Gastroenterol. 2006, 101(5):1012-1023.
-
(2006)
Am. J. Gastroenterol.
, vol.101
, Issue.5
, pp. 1012-1023
-
-
Nguyen, G.C.1
Torres, E.A.2
Regueiro, M.3
Bromfield, G.4
Bitton, A.5
Stempak, J.6
Dassopoulos, T.7
Schumm, P.8
Gregory, F.J.9
Griffiths, A.M.10
Hanauer, S.B.11
Hanson, J.12
Harris, M.L.13
Kane, S.V.14
Orkwis, H.K.15
Lahaie, R.16
Oliva-Hemker, M.17
Pare, P.18
Wild, G.E.19
Rioux, J.D.20
Yang, H.21
Duerr, R.H.22
Cho, J.H.23
Steinhart, A.H.24
Brant, S.R.25
Silverberg, M.S.26
more..
-
31
-
-
0035978533
-
A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease
-
Ogura Y., Bonen D.K., Inohara N., Nicolae D.L., Chen F.F., Ramos R., Britton H., Moran T., Karaliuskas R., Duerr R.H., Achkar J.P., Brant S.R., Bayless T.M., Kirschner B.S., Hanauer S.B., Nunez G., Cho J.H. A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease. Nature 2001, 411(6837):603-606.
-
(2001)
Nature
, vol.411
, Issue.6837
, pp. 603-606
-
-
Ogura, Y.1
Bonen, D.K.2
Inohara, N.3
Nicolae, D.L.4
Chen, F.F.5
Ramos, R.6
Britton, H.7
Moran, T.8
Karaliuskas, R.9
Duerr, R.H.10
Achkar, J.P.11
Brant, S.R.12
Bayless, T.M.13
Kirschner, B.S.14
Hanauer, S.B.15
Nunez, G.16
Cho, J.H.17
-
32
-
-
0033973568
-
Clinical phenotype is related to HLA genotype in the peripheral arthropathies of inflammatory bowel disease
-
Orchard T.R., Thiyagaraja S., Welsh K.I., Wordsworth B.P., Hill Gaston J.S., Jewell D.P. Clinical phenotype is related to HLA genotype in the peripheral arthropathies of inflammatory bowel disease. Gastroenterology 2000, 118(2):274-278.
-
(2000)
Gastroenterology
, vol.118
, Issue.2
, pp. 274-278
-
-
Orchard, T.R.1
Thiyagaraja, S.2
Welsh, K.I.3
Wordsworth, B.P.4
Hill Gaston, J.S.5
Jewell, D.P.6
-
33
-
-
0036731117
-
Uveitis and erythema nodosum in inflammatory bowel disease: clinical features and the role of HLA genes
-
Orchard T.R., Chua C.N., Ahmad T., Cheng H., Welsh K.I., Jewell D.P. Uveitis and erythema nodosum in inflammatory bowel disease: clinical features and the role of HLA genes. Gastroenterology 2002, 123(3):714-718.
-
(2002)
Gastroenterology
, vol.123
, Issue.3
, pp. 714-718
-
-
Orchard, T.R.1
Chua, C.N.2
Ahmad, T.3
Cheng, H.4
Welsh, K.I.5
Jewell, D.P.6
-
34
-
-
84859437871
-
Association of STAT4 with rheumatoid arthritis: a replication study in three European populations
-
Orozco G., Alizadeh B.Z., Delgado-Vega A.M., Gonzalez-Gay M.A., Balsa A., Pascual-Salcedo D., Fernandez-Gutierrez B., Gonzalez-Escribano M.F., Petersson I.F., van Riel P.L., Barrera P., Coenen M.J., Radstake T.R., van Leeuwen M.A., Wijmenga C., Koeleman B.P., Alarcon-Riquelme M., Martin J. Association of STAT4 with rheumatoid arthritis: a replication study in three European populations. Arthritis Rheum. 2008, 58(7):1974-1980.
-
(2008)
Arthritis Rheum.
, vol.58
, Issue.7
, pp. 1974-1980
-
-
Orozco, G.1
Alizadeh, B.Z.2
Delgado-Vega, A.M.3
Gonzalez-Gay, M.A.4
Balsa, A.5
Pascual-Salcedo, D.6
Fernandez-Gutierrez, B.7
Gonzalez-Escribano, M.F.8
Petersson, I.F.9
van Riel, P.L.10
Barrera, P.11
Coenen, M.J.12
Radstake, T.R.13
van Leeuwen, M.A.14
Wijmenga, C.15
Koeleman, B.P.16
Alarcon-Riquelme, M.17
Martin, J.18
-
35
-
-
37349050665
-
Increased expression and activation of IL-12-induced STAT4 signaling in the mucosa of ulcerative colitis patients
-
Pang Y.H., Zheng C.Q., Yang X.Z., Zhang W.J. Increased expression and activation of IL-12-induced STAT4 signaling in the mucosa of ulcerative colitis patients. Cell. Immunol. 2007, 248(2):115-120.
-
(2007)
Cell. Immunol.
, vol.248
, Issue.2
, pp. 115-120
-
-
Pang, Y.H.1
Zheng, C.Q.2
Yang, X.Z.3
Zhang, W.J.4
-
36
-
-
2442585704
-
Functional variants of OCTN cation transporter genes are associated with Crohn disease
-
Peltekova V.D., Wintle R.F., Rubin L.A., Amos C.I., Huang Q., Gu X., Newman B., Van Oene M., Cescon D., Greenberg G., Griffiths A.M., St George-Hyslop P.H., Siminovitch K.A. Functional variants of OCTN cation transporter genes are associated with Crohn disease. Nat. Genet. 2004, 36(5):471-475.
-
(2004)
Nat. Genet.
, vol.36
, Issue.5
, pp. 471-475
-
-
Peltekova, V.D.1
Wintle, R.F.2
Rubin, L.A.3
Amos, C.I.4
Huang, Q.5
Gu, X.6
Newman, B.7
Van Oene, M.8
Cescon, D.9
Greenberg, G.10
Griffiths, A.M.11
St George-Hyslop, P.H.12
Siminovitch, K.A.13
-
37
-
-
0037043658
-
Inflammatory bowel disease
-
Podolsky D.K. Inflammatory bowel disease. N. Engl. J. Med. 2002, 347(6):417-429.
-
(2002)
N. Engl. J. Med.
, vol.347
, Issue.6
, pp. 417-429
-
-
Podolsky, D.K.1
-
38
-
-
34548427925
-
STAT4 and the risk of rheumatoid arthritis and systemic lupus erythematosus
-
Remmers E.F., Plenge R.M., Lee A.T., Graham R.R., Hom G., Behrens T.W., de Bakker P.I., Le J.M., Lee H.S., Batliwalla F., Li W., Masters S.L., Booty M.G., Carulli J.P., Padyukov L., Alfredsson L., Klareskog L., Chen W.V., Amos C.I., Criswell L.A., Seldin M.F., Kastner D.L., Gregersen P.K. STAT4 and the risk of rheumatoid arthritis and systemic lupus erythematosus. N. Engl. J. Med. 2007, 357(10):977-986.
-
(2007)
N. Engl. J. Med.
, vol.357
, Issue.10
, pp. 977-986
-
-
Remmers, E.F.1
Plenge, R.M.2
Lee, A.T.3
Graham, R.R.4
Hom, G.5
Behrens, T.W.6
de Bakker, P.I.7
Le, J.M.8
Lee, H.S.9
Batliwalla, F.10
Li, W.11
Masters, S.L.12
Booty, M.G.13
Carulli, J.P.14
Padyukov, L.15
Alfredsson, L.16
Klareskog, L.17
Chen, W.V.18
Amos, C.I.19
Criswell, L.A.20
Seldin, M.F.21
Kastner, D.L.22
Gregersen, P.K.23
more..
-
39
-
-
2442571121
-
Autoimmune disorders and extraintestinal manifestations in first-degree familial and sporadic inflammatory bowel disease: a case-control study
-
Ricart E., Panaccione R., Loftus E.V., Tremaine W.J., Harmsen W.S., Zinsmeister A.R., Sandborn W.J. Autoimmune disorders and extraintestinal manifestations in first-degree familial and sporadic inflammatory bowel disease: a case-control study. Inflamm. Bowel. Dis. 2004, 10(3):207-214.
-
(2004)
Inflamm. Bowel. Dis.
, vol.10
, Issue.3
, pp. 207-214
-
-
Ricart, E.1
Panaccione, R.2
Loftus, E.V.3
Tremaine, W.J.4
Harmsen, W.S.5
Zinsmeister, A.R.6
Sandborn, W.J.7
-
40
-
-
0033910870
-
Genomewide search in Canadian families with inflammatory bowel disease reveals two novel susceptibility loci
-
Rioux J.D., Silverberg M.S., Daly M.J., Steinhart A.H., McLeod R.S., Griffiths A.M., Green T., Brettin T.S., Stone V., Bull S.B., Bitton A., Williams C.N., Greenberg G.R., Cohen Z., Lander E.S., Hudson T.J., Siminovitch K.A. Genomewide search in Canadian families with inflammatory bowel disease reveals two novel susceptibility loci. Am. J. Hum. Genet. 2000, 66(6):1863-1870.
-
(2000)
Am. J. Hum. Genet.
, vol.66
, Issue.6
, pp. 1863-1870
-
-
Rioux, J.D.1
Silverberg, M.S.2
Daly, M.J.3
Steinhart, A.H.4
McLeod, R.S.5
Griffiths, A.M.6
Green, T.7
Brettin, T.S.8
Stone, V.9
Bull, S.B.10
Bitton, A.11
Williams, C.N.12
Greenberg, G.R.13
Cohen, Z.14
Lander, E.S.15
Hudson, T.J.16
Siminovitch, K.A.17
-
41
-
-
0030912011
-
Genetic markers may predict disease behavior in patients with ulcerative colitis
-
Roussomoustakaki M., Satsangi J., Welsh K., Louis E., Fanning G., Targan S., Landers C., Jewell D.P. Genetic markers may predict disease behavior in patients with ulcerative colitis. Gastroenterology 1997, 112(6):1845-1853.
-
(1997)
Gastroenterology
, vol.112
, Issue.6
, pp. 1845-1853
-
-
Roussomoustakaki, M.1
Satsangi, J.2
Welsh, K.3
Louis, E.4
Fanning, G.5
Targan, S.6
Landers, C.7
Jewell, D.P.8
-
42
-
-
65549154046
-
The STAT4 gene influences the genetic predisposition to systemic sclerosis phenotype
-
Rueda B., Broen J., Simeon C., Hesselstrand R., Diaz B., Suarez H., Ortego-Centeno N., Riemekasten G., Fonollosa V., Vonk M.C., van den Hoogen F.H., Sanchez-Roman J., Aguirre-Zamorano M.A., Garcia-Portales R., Pros A., Camps M.T., Gonzalez-Gay M.A., Coenen M.J., Airo P., Beretta L., Scorza R., van Laar J., Gonzalez-Escribano M.F., Nelson J.L., Radstake T.R., Martin J. The STAT4 gene influences the genetic predisposition to systemic sclerosis phenotype. Hum. Mol. Genet. 2009, 18(11):2071-2077.
-
(2009)
Hum. Mol. Genet.
, vol.18
, Issue.11
, pp. 2071-2077
-
-
Rueda, B.1
Broen, J.2
Simeon, C.3
Hesselstrand, R.4
Diaz, B.5
Suarez, H.6
Ortego-Centeno, N.7
Riemekasten, G.8
Fonollosa, V.9
Vonk, M.C.10
van den Hoogen, F.H.11
Sanchez-Roman, J.12
Aguirre-Zamorano, M.A.13
Garcia-Portales, R.14
Pros, A.15
Camps, M.T.16
Gonzalez-Gay, M.A.17
Coenen, M.J.18
Airo, P.19
Beretta, L.20
Scorza, R.21
van Laar, J.22
Gonzalez-Escribano, M.F.23
Nelson, J.L.24
Radstake, T.R.25
Martin, J.26
more..
-
43
-
-
84894353884
-
Toward an integrated clinical, molecular and serological classification of inflammatory bowel disease: Report of a Working Party of the 2005 Montreal World Congress of Gastroenterology
-
Silverberg M.S., Satsangi J., Ahmad T., Arnott I.D., Bernstein C.N., Brant S.R., Caprilli R., Colombel J.F., Gasche C., Geboes K., Jewell D.P., Karban A., Loftus E.V., Pena A.S., Riddell R.H., Sachar D.B., Schreiber S., Steinhart A.H., Targan S.R., Vermeire S., Warren B.F. Toward an integrated clinical, molecular and serological classification of inflammatory bowel disease: Report of a Working Party of the 2005 Montreal World Congress of Gastroenterology. Can. J. Gastroenterol. 2005, 19(Suppl A):5-36.
-
(2005)
Can. J. Gastroenterol.
, vol.19
, Issue.SUPPL. A
, pp. 5-36
-
-
Silverberg, M.S.1
Satsangi, J.2
Ahmad, T.3
Arnott, I.D.4
Bernstein, C.N.5
Brant, S.R.6
Caprilli, R.7
Colombel, J.F.8
Gasche, C.9
Geboes, K.10
Jewell, D.P.11
Karban, A.12
Loftus, E.V.13
Pena, A.S.14
Riddell, R.H.15
Sachar, D.B.16
Schreiber, S.17
Steinhart, A.H.18
Targan, S.R.19
Vermeire, S.20
Warren, B.F.21
more..
-
44
-
-
21644450146
-
The role of the T cell in autoimmune inflammation
-
Skapenko A., Leipe J., Lipsky P.E., Schulze-Koops H. The role of the T cell in autoimmune inflammation. Arthritis Res. Ther. 2005, 7(Suppl 2):S4-S14.
-
(2005)
Arthritis Res. Ther.
, vol.7
, Issue.2 SUPPL.
-
-
Skapenko, A.1
Leipe, J.2
Lipsky, P.E.3
Schulze-Koops, H.4
-
45
-
-
33846966636
-
A brief history of T(H)17, the first major revision in the T(H)1/T(H)2 hypothesis of T cell-mediated tissue damage
-
Steinman L. A brief history of T(H)17, the first major revision in the T(H)1/T(H)2 hypothesis of T cell-mediated tissue damage. Nat. Med. 2007, 13(2):139-145.
-
(2007)
Nat. Med.
, vol.13
, Issue.2
, pp. 139-145
-
-
Steinman, L.1
-
46
-
-
2442519456
-
Genetic variation in DLG5 is associated with inflammatory bowel disease
-
Stoll M., Corneliussen B., Costello C.M., Waetzig G.H., Mellgard B., Koch W.A., Rosenstiel P., Albrecht M., Croucher P.J., Seegert D., Nikolaus S., Hampe J., Lengauer T., Pierrou S., Foelsch U.R., Mathew C.G., Lagerstrom-Fermer M., Schreiber S. Genetic variation in DLG5 is associated with inflammatory bowel disease. Nat. Genet. 2004, 36(5):476-480.
-
(2004)
Nat. Genet.
, vol.36
, Issue.5
, pp. 476-480
-
-
Stoll, M.1
Corneliussen, B.2
Costello, C.M.3
Waetzig, G.H.4
Mellgard, B.5
Koch, W.A.6
Rosenstiel, P.7
Albrecht, M.8
Croucher, P.J.9
Seegert, D.10
Nikolaus, S.11
Hampe, J.12
Lengauer, T.13
Pierrou, S.14
Foelsch, U.R.15
Mathew, C.G.16
Lagerstrom-Fermer, M.17
Schreiber, S.18
-
47
-
-
44949149145
-
Specificity of the STAT4 genetic association for severe disease manifestations of systemic lupus erythematosus
-
Taylor K.E., Remmers E.F., Lee A.T., Ortmann W.A., Plenge R.M., Tian C., Chung S.A., Nititham J., Hom G., Kao A.H., Demirci F.Y., Kamboh M.I., Petri M., Manzi S., Kastner D.L., Seldin M.F., Gregersen P.K., Behrens T.W., Criswell L.A. Specificity of the STAT4 genetic association for severe disease manifestations of systemic lupus erythematosus. PLoS Genet. 2008, 4(5):e1000084.
-
(2008)
PLoS Genet.
, vol.4
, Issue.5
-
-
Taylor, K.E.1
Remmers, E.F.2
Lee, A.T.3
Ortmann, W.A.4
Plenge, R.M.5
Tian, C.6
Chung, S.A.7
Nititham, J.8
Hom, G.9
Kao, A.H.10
Demirci, F.Y.11
Kamboh, M.I.12
Petri, M.13
Manzi, S.14
Kastner, D.L.15
Seldin, M.F.16
Gregersen, P.K.17
Behrens, T.W.18
Criswell, L.A.19
-
48
-
-
28444469783
-
Autoimmune-associated lymphoid tyrosine phosphatase is a gain-of-function variant
-
Vang T., Congia M., Macis M.D., Musumeci L., Orru V., Zavattari P., Nika K., Tautz L., Tasken K., Cucca F., Mustelin T., Bottini N. Autoimmune-associated lymphoid tyrosine phosphatase is a gain-of-function variant. Nat. Genet. 2005, 37(12):1317-1319.
-
(2005)
Nat. Genet.
, vol.37
, Issue.12
, pp. 1317-1319
-
-
Vang, T.1
Congia, M.2
Macis, M.D.3
Musumeci, L.4
Orru, V.5
Zavattari, P.6
Nika, K.7
Tautz, L.8
Tasken, K.9
Cucca, F.10
Mustelin, T.11
Bottini, N.12
-
49
-
-
28544444993
-
Current status of genetics research in inflammatory bowel disease
-
Vermeire S., Rutgeerts P. Current status of genetics research in inflammatory bowel disease. Genes Immun. 2005, 6(8):637-645.
-
(2005)
Genes Immun.
, vol.6
, Issue.8
, pp. 637-645
-
-
Vermeire, S.1
Rutgeerts, P.2
-
50
-
-
0346734196
-
The susceptibility to experimental myasthenia gravis of STAT6-/- and STAT4-/- BALB/c mice suggests a pathogenic role of Th1 cells
-
Wang W., Ostlie N.S., Conti-Fine B.M., Milani M. The susceptibility to experimental myasthenia gravis of STAT6-/- and STAT4-/- BALB/c mice suggests a pathogenic role of Th1 cells. J. Immunol. 2004, 172(1):97-103.
-
(2004)
J. Immunol.
, vol.172
, Issue.1
, pp. 97-103
-
-
Wang, W.1
Ostlie, N.S.2
Conti-Fine, B.M.3
Milani, M.4
-
51
-
-
9644257195
-
Signaling by IL-12 and IL-23 and the immunoregulatory roles of STAT4
-
Watford W.T., Hissong B.D., Bream J.H., Kanno Y., Muul L., O'Shea J.J. Signaling by IL-12 and IL-23 and the immunoregulatory roles of STAT4. Immunol. Rev. 2004, 202:139-156.
-
(2004)
Immunol. Rev.
, vol.202
, pp. 139-156
-
-
Watford, W.T.1
Hissong, B.D.2
Bream, J.H.3
Kanno, Y.4
Muul, L.5
O'Shea, J.J.6
-
52
-
-
60749113903
-
Extraintestinal manifestations of inflammatory bowel disease
-
Williams H., Walker D., Orchard T.R. Extraintestinal manifestations of inflammatory bowel disease. Curr. Gastroenterol. Rep. 2008, 10(6):597-605.
-
(2008)
Curr. Gastroenterol. Rep.
, vol.10
, Issue.6
, pp. 597-605
-
-
Williams, H.1
Walker, D.2
Orchard, T.R.3
-
53
-
-
12744274602
-
Association analysis of SLC22A4, SLC22A5 and DLG5 in Japanese patients with Crohn disease
-
Yamazaki K., Takazoe M., Tanaka T., Ichimori T., Saito S., Iida A., Onouchi Y., Hata A., Nakamura Y. Association analysis of SLC22A4, SLC22A5 and DLG5 in Japanese patients with Crohn disease. J. Hum. Genet. 2004, 49(12):664-668.
-
(2004)
J. Hum. Genet.
, vol.49
, Issue.12
, pp. 664-668
-
-
Yamazaki, K.1
Takazoe, M.2
Tanaka, T.3
Ichimori, T.4
Saito, S.5
Iida, A.6
Onouchi, Y.7
Hata, A.8
Nakamura, Y.9
-
54
-
-
27944464550
-
Single nucleotide polymorphisms in TNFSF15 confer susceptibility to Crohn's disease
-
Yamazaki K., McGovern D., Ragoussis J., Paolucci M., Butler H., Jewell D., Cardon L., Takazoe M., Tanaka T., Ichimori T., Saito S., Sekine A., Iida A., Takahashi A., Tsunoda T., Lathrop M., Nakamura Y. Single nucleotide polymorphisms in TNFSF15 confer susceptibility to Crohn's disease. Hum. Mol. Genet. 2005, 14:3499-3506.
-
(2005)
Hum. Mol. Genet.
, vol.14
, pp. 3499-3506
-
-
Yamazaki, K.1
McGovern, D.2
Ragoussis, J.3
Paolucci, M.4
Butler, H.5
Jewell, D.6
Cardon, L.7
Takazoe, M.8
Tanaka, T.9
Ichimori, T.10
Saito, S.11
Sekine, A.12
Iida, A.13
Takahashi, A.14
Tsunoda, T.15
Lathrop, M.16
Nakamura, Y.17
-
55
-
-
34347357508
-
Association analysis of genetic variants in IL23R, ATG16L1 and 5p13.1 loci with Crohn's disease in Japanese patients
-
Yamazaki K., Onouchi Y., Takazoe M., Kubo M., Nakamura Y., Hata A. Association analysis of genetic variants in IL23R, ATG16L1 and 5p13.1 loci with Crohn's disease in Japanese patients. J. Hum. Genet. 2007, 52(7):575-583.
-
(2007)
J. Hum. Genet.
, vol.52
, Issue.7
, pp. 575-583
-
-
Yamazaki, K.1
Onouchi, Y.2
Takazoe, M.3
Kubo, M.4
Nakamura, Y.5
Hata, A.6
-
56
-
-
70449719062
-
Contribution of IL23R but not ATG16L1 to Crohn's disease susceptibility in Koreans
-
Yang S.K., Park M., Lim J., Park S.H., Ye B.D., Lee I., Song K. Contribution of IL23R but not ATG16L1 to Crohn's disease susceptibility in Koreans. Inflamm. Bowel. Dis. 2009.
-
(2009)
Inflamm. Bowel. Dis.
-
-
Yang, S.K.1
Park, M.2
Lim, J.3
Park, S.H.4
Ye, B.D.5
Lee, I.6
Song, K.7
-
57
-
-
54549122571
-
STAT4: a risk factor for type 1 diabetes?
-
Zervou M.I., Mamoulakis D., Panierakis C., Boumpas D.T., Goulielmos G.N. STAT4: a risk factor for type 1 diabetes?. Hum. Immunol. 2008, 69(10):647-650.
-
(2008)
Hum. Immunol.
, vol.69
, Issue.10
, pp. 647-650
-
-
Zervou, M.I.1
Mamoulakis, D.2
Panierakis, C.3
Boumpas, D.T.4
Goulielmos, G.N.5
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