Docosahexaenoic acid metabolome in neural tumors: Identification of cytotoxic intermediates

FASEB Journal

Volumn 24, Issue 3, 2010, Pages 906-915

  Gleissman, Helena ^a   Yang, Rong ^b   Martinod, Kimberly ^b   Lindskog, Magnus ^a   Serhan, Charles N ^b   Johnsen, John Inge ^a   Kogner, Per ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Cancer; Docosanoids; Lipidomics; Neuroblastoma; Omega 3 fatty acids

Indexed keywords

17 HYDROPEROXYDOCOSAHEXAENOIC ACID; 17 HYDROXYDOCOSAHEXAENOIC ACID; ALPHA TOCOPHEROL; ARACHIDONATE 15 LIPOXYGENASE; CELECOXIB; DOCOSAHEXAENOIC ACID; DRUG METABOLITE; UNCLASSIFIED DRUG; 17 HYDROXY 4,7,10,13,15,19 DOCOSAHEXAENOIC ACID; 17-HYDROXY-4,7,10,13,15,19-DOCOSAHEXAENOIC ACID; FATTY ACID;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; AUTOOXIDATION; CELL PROTECTION; CONTROLLED STUDY; CYTOTOXICITY; DRUG CONJUGATION; DRUG CYTOTOXICITY; DRUG METABOLISM; HUMAN; HUMAN CELL; IC 50; LIQUID CHROMATOGRAPHY; METABOLOME; NEUROBLASTOMA; NEUROBLASTOMA CELL; PRIORITY JOURNAL; TANDEM MASS SPECTROMETRY; CELL SURVIVAL; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; FLOW CYTOMETRY; IMMUNOBLOTTING; MASS FRAGMENTOGRAPHY; METABOLISM; SOLID PHASE EXTRACTION; TUMOR CELL LINE;

ARACHIDONATE 15-LIPOXYGENASE; CELL LINE, TUMOR; CELL SURVIVAL; CHROMATOGRAPHY, LIQUID; DOCOSAHEXAENOIC ACIDS; FATTY ACIDS; FLOW CYTOMETRY; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HUMANS; IMMUNOBLOTTING; NEUROBLASTOMA; SOLID PHASE EXTRACTION; TANDEM MASS SPECTROMETRY;

EID: 77951064881     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.09-137919     Document Type: Article

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