DHA hydroperoxides as a potential inducer of neuronal cell death: A mitochondrial dysfunction-mediated pathway

Journal of Clinical Biochemistry and Nutrition

Volumn 43, Issue 1, 2008, Pages 26-33

  Liu, Xuebo ^a   Shibata, Takahiro ^a   Hisaka, Shinsuke ^a   Kawai, Yoshichika ^a,b   Osawa, Toshihiko ^a  

^a NAGOYA UNIVERSITY   (Japan)

^b UNIVERSITY OF TOKUSHIMA   (Japan)

Author keywords

Apoptosis; DHA hydroperoxides; Lipid peroxidation; Mitochondria dysfunction; Neurodegeneration

Indexed keywords

ARACHIDONIC ACID HYDROPEROXIDE; CASPASE 3; CYTOCHROME C; DNA; DOCOSAHEXAENOIC ACID HYDROPEROXIDE; HYDROPEROXIDE; LINOLEIC ACID HYDROPEROXIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PEROXIDE; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DNA FRAGMENTATION; ENZYME ACTIVITY; ENZYME RELEASE; HUMAN; HUMAN CELL; LIPID PEROXIDATION; MITOCHONDRIAL MEMBRANE POTENTIAL; NERVE CELL NECROSIS; NERVE CELL STIMULATION; NEUROBLASTOMA CELL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN SECRETION; SIGNAL TRANSDUCTION;

EID: 50349091182     PISSN: 09120009     EISSN: None     Source Type: Journal    
DOI: 10.3164/jcbn.2008040     Document Type: Article

References (36)

1. Porter, N.A., Caldwell, S.E., and Mills, K.A.: Mechanisms of free radical oxidation of unsaturated lipids. Lipids, 30, 277-290, 1995.
2. Gutteridge, J.M. and Halliwell, B.: The measurement and mechanism of lipid peroxidation in biological systems. Trends Biochem. Sci., 15, 129-135, 1990.
3. Shibata, T., Iio, K., Kawai, Y., Shibata, N., Kawaguchi, M., Toi, S., Kobayashi, M., Kobayashi, M., Yamamoto, K., and Uchida, K.: Identification of a lipid peroxidation product as a potential trigger of the p53 pathway. J. Biol. Chem., 281, 1196-1204, 2006.
4. ε-(succinyl) lysine (SUL) in vivo: a novel marker for docosahexaenoic acid-derived protein modification. J. Lip. Res., 47, 1386-1398, 2006.
5. Standstrom, P.A., Pardi, D., Tebbey, P.W., Dudek, R.W., Terrian, D.M., Folks, T.M., and Buttke, T.M.: Lipid hydroperoxide-induced apoptosis: lack of inhibition by Bcl-2 over-expression. FEBS Lett., 365, 66-70, 1995.
6. Suraneni, V., Mahipal, K., Subhashini, J., Reddy, M.C., Reddy, M.M., Anilkumara, K., Roy, K.R., Reddy, G.V., and Reddanna, P.: Effect of 15-lipoxygenase metabolites, 15-(S)-HPETE and15-(S)-HETE on chronic myelogenous leukemia cell line K-562: Reactive oxygen species (ROS) mediate caspase-dependent apoptosis. Biochem. Pharmacol., 74, 202-214, 2007.
7. Bernoud-Hubac, N., Davies, S., Boutaud, O., Montine, T., and Roberts, II. L.: Formation of highly reactive gamma-ketoaldehydes (neuroketals) as products of the neuroprostane pathway. J. Biol. Chem., 276, 30964-30970, 2001.
8. Forman, H.J. and Dickinson, D.A.: Introduction to serial reviews on 4-hydroxy-2-nonenal as a signaling molecule. Free Radic. Biol. Med., 37, 594-596, 2004.
9. Lossi, L. and Gambino, G: Apoptosis of the cerebellar neurons. Histo. Histophathol., 23, 367-380, 2008.
10. ε-(Hexanonyl) lysine in protein exposed to lipid hydroperoxide. J. Biol. Chem., 274, 20406-20414, 1999.
11. Hui-Chun, Y., Tsai, A.-L., and Wang, L.-H.: Reaction mechanisms of 15-hydroperoxyeicosatetraenoic acid catalyzed by human prostacyclin and thromboxane synthases. Arc. Biochem. Biophys., 461, 159-168, 2007.
12. Liu, X. and Osawa, T.: Cis astaxanthin and especially 9-cis astaxanthin exhibits a higher antioxidant activity in vitro compared to the all-trans isomer. Biochem. Biophys. Res. Commun., 357, 187-193, 2007.
13. Pallotti, F. and Lenaz, G.: Isolation and subfractionation of mitochondria from animal cells and tissue culture lines. Methods Cell Biol., 80, 3-44, 2007.
14. Ko, C.H., Shen, S.H., Yang, L.Y., Lin, C.W., and Chen, YC.: Gossypol reduction of tumor growth through ROS-dependent mitochondria pathway in human colorectal carcinoma cells. Int. J. Cancer, 121, 1670-1679, 2007.
15. Andersen, J.K.: Does neuronal loss in Parkinson's disease involve programmed cell death?. BioEssays, 23, 640-646, 2001.
16. Cutler, R.G., Kelly, J., Storie, K., Pedersen, W.A., Tammara, A., Hatanpaa, K., Troncoso, J.C., and Mattson, M.P.: Involvement of oxidative stress-induced abnormalities in ceramide and cholesterol metabolism in brain aging and Alzheimer's disease. Proc. Natl. Acad. Sci., 101, 2070-2075, 2004.
17. Butterfield, D.A., Reed, T., Newman, SF., and Sultana, R.: Roles of amyloid beta-peptide-associated oxidative stress and brain protein modifications in the pathogenesis of Alzheimer's disease and mild cognitive impairment. Free Radic. Biol. Med., 43, 658-677, 2007.
18. Osawa, T.: Nephroprotective and hepatoprotective effects of curcuminoids. Adv. Exp. Med. Biol., 595, 407-423, 2007.
19. Yuan, H., Zheng, J.C., Liu, P., Zhang, S.F., Xu, J.Y., and Bai, L.M.: Pathogenesis of Parkinson's disease: oxidative stress, environmental impact factors and inflammatory processes. Neurosci. Bull., 23, 125-130, 2007.
20. Moraine, T.J. and Morrow, J.D.: Fatty acid oxidation in the pathogenesis of Alzheimer's disease. Am. J. Pathol., 166, 1283-1289, 2005.
21. Tapiero, H., Ba, GN., Couvreur, P., and Tew, K.D.: Polyunsaturated fatty acids (PUFA) and eicosanoids in human health and pathologies. Biomed. Pharmacother., 56, 215-222, 2002.
22. Jian, W.Y., Arora, J.S., Oe, T., Shuvaev, V.V., and Blair, I.A.: Induction of endothelial cell apoptosis by lipid hydroperoxide-derived bifunctional electrophiles. Free Radic. Biol. Med., 39, 1162-1176, 2005.
23. Maccarrone, M., Ranalli, M., Bellincampi, L., Salucci, M.L., Sabatini, S., Melino, G, and Alessandro, F.A.: Activation of different lipoxygenase isozymes induces apoptosis in human erythroleukemia and neuroblastoma cells. Biochem. Biophys. Res. Commun., 272, 345-350, 2000.
24. Zhu, X., Su, B., Wang, X., Smith, M.A., and Perrya, G: Causes of oxidative stress in Alzheimer disease. Cell. Mol. Life Sci., In press, 2007.
25. Shirai, N. and Suzuki, H.: Effect of dietary docosahexaenoic acid and catechins on maze behavior in mice. Ann. Nutr. Metab., 48, 51-58, 2004.
26. Kim, H.Y, Akbar, M., Lau, A., and Edsall, L.: Inhibition of neuronal apoptosis by docosahexaenoic acid (22:6n-3), Role of phosphatidylserine in antiapoptotic effect. J. Biol. Chem., 275, 35215-35223, 2000.
27. Rodriguez de., Turco, E.B., Belayev, L., Liu, Y., Busto, R., Parkins, N., Bazan, N.G, and Ginsberg, M.D.: Systemic fatty acid responses to transient focal cerebral ischemia: influence of neuroprotectant therapy with human albumin. J. Neurochem., 83, 515-524, 2002.
28. Hashimoto, M., Shinozuka, K., Gamoh, S., Tanabe, Y., Hossain, M.S., Kwon, Y.M., Hata, N., Misawa, Y., Kunitomo, M., and Masumura, S.: The hypotensive effect of docosahexaenoic acid is associated with the enhanced release of ATP from the caudal artery of aged rats. J. Nutr., 129, 70-76, 1999.
29. Bazan, N.G., Palacios-Pelaez, R., and Lukiw, W.J.: Hypoxia signaling: significance in Alzheimer's disease. Mol. Neurobiol., 26, 283-298, 2002.
30. Esterbauer, H., Schaur, R.J., and Zollner, H.: Chemistry and biochemistry of 4-hydroxynonenal, malondialdehyde and related aldehydes. Free Radic. Biol. Med., 11, 81-128, 1991.
31. Shamo-Nagai, M., Maruyama, W., Kato, Y., Isobe, K., Tanaka, M., Naoi, M., and Osawa, T.: An inhibitor of mitochondrial complex I, rotenone, inactivates proteasome by oxidative modification and induces aggregation of oxidized proteins in SH-SY5Y cells. J. Neurosci. Res., 74, 589-597, 2003.
32. Naoi, M., Maruyama, W., Shimoto-Nagai, M., Yi, H., Akao, Y., and Tanaka, M.: Oxidative stress in mitochondria: Decision of survival and death of neurons in neurodegenerative disorders. Molecular Neurobiology, 31, 81-93, 2005.
33. Montine, K.S., Quinn, J.F., Zhang, J., Fessel, J.P., Roberts II, L.J., Morrow, J.D., and Montine, T.J.: Isoprostanes and related products of lipid peroxidation in neurodegenerative disease. Chem. Phys. Lip., 128, 117-124, 2004.
34. Negre-Salvayre, A., Coatrieus, C., Ingueneau, C., and Salvayre, R.: Advanced lipid peroxidation end products in oxidative damage to proteins. Potential role in diseases and therapeutic prospects for the inhibitors. Bri. J. Pharmacol., In press, 2007.
35. Haddad, J.J.: Redox and oxidant-mediated regulation of apoptosis signaling pathways: immuno-pharmaco-redox conception of oxidative siege versus cell death commitiment. Int. Immunopharmacol., 4, 475-493, 2004.
36. Lin, M.T. and Flint Beal, M.: Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases. Nature, 433, 787-795, 2006.