Overexpression of the mouse Fas gene in human Hep3B hepatoma cells overcomes their resistance to Fas-mediated apoptosis

Journal of Hepatology

Volumn 36, Issue 3, 2002, Pages 385-394

  Lamboley, Christelle ^a   Bringuier, Annie France ^a   Camus, Emmanuel ^a   Lardeux, Bernard ^a   Groyer, André ^a   Feldmann, Gérard ^a  

^a INSERM   (France)

Author keywords

Apoptosis; Fas CD95 Apo 1; Gene; Human hepatoma cells

Indexed keywords

CASPASE; DNA FRAGMENT; FAS ANTIBODY; FAS LIGAND; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE;

APOPTOSIS; ARTICLE; CELL DEATH; CELL MEMBRANE; CHROMATIN CONDENSATION; CONTROLLED STUDY; FLOW CYTOMETRY; GENE OVEREXPRESSION; GENETIC TRANSFECTION; HEPATOMA CELL; HUMAN; HUMAN CELL; LIVER CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RECEPTOR BINDING;

ANTIGENS, CD95; CARCINOMA, HEPATOCELLULAR; CASPASE 3; CASPASE 8; CASPASE 9; CASPASES; CELL MEMBRANE; CHROMATIN; COENZYME A LIGASES; DNA FRAGMENTATION; ESCHERICHIA COLI PROTEINS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LIVER NEOPLASMS; PHENOTYPE; POINT MUTATION; POLY(ADP-RIBOSE) POLYMERASES; PROTEINS; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0036192025     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-8278(01)00284-7     Document Type: Article

References (48)

1. Mechanisms and genes of cellular suicide
2. The hallmarks of cancer
3. Programmed cell death: Apoptosis and oncogenesis
4. The molecular biology of carcinogenesis
5. The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis
6. Fas-mediated apoptosis in primary cultured mouse hepatocytes
7. Targeted mutation in the Fas gene causes hyperplasia in peripheral lymphoid organs and liver
8. Involvement of the CD95 (APO-1/Fas) receptor and ligand in liver damage
9. Apoptosis and hepatobiliary disease
10. Liver apoptosis
11. Death receptors in liver biology and pathobiology
12. The Fas death factor
13. Fas ligand-induced apoptosis
14. Mechanisms of CD95 (APO-1/Fas)-mediated apoptosis
15. Apoptosis by death factor
16. Two CD95 (APO-1/Fas) signaling pathways
17. Involvement of Fas system-mediated apoptosis in pathogenesis of viral hepatitis
18. Apoptosis and pathogenesis of viral hepatitis C - An update
19. The Fas system is not significantly involved in apoptosis in human hepatocellular carcinoma
20. Fas antigen expression and its relationship with apoptosis in human hepatocellular carcinoma and noncancerous tissues
21. Expression of Fas-related genes in human hepatocellular carcinomas
22. Fas antigen expression in hepatocellular carcinoma tissues
23. The alteration of Fas receptor and ligand system in hepatocellular carcinomas: How do hepatoma cells escape from the host immune surveillance in vivo?
24. Resistance to Fas-mediated apoptosis in human hepatoma cells
25. Apoptotic behaviour of hepatic and extra-hepatic tumor cell lines differs after Fas stimulation
26. The cDNA structure, expression, and chromosomal assignment of the mouse Fas antigen
27. High-efficiency transformation of mammalian cells by plasmid DNA
28. A selective procedure for DNA extraction from apoptotic cells applicable for gel electrophoresis and flow cytometry
29. A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells
30. Cleavage of poly(ADP-ribose) polymerase: A sensitive parameter to study cell death
31. Lymphocyte apoptosis induced by CD95 (APO-1/Fas) ligand-expressing tumor cells - A mechanism of immune evasion?
32. Human lung carcinomas express Fas ligand
33. Drug-induced apoptosis in hepatoma cells is mediated by the CD95 (APO-1/Fas) receptor/ligand system and involves activation of wild-type p53
34. Deficient activation of the CD95 (APO-1/Fas) system in drug-resistant cells
35. Apoptosis in human hepatoma cell lines by chemotherapeutic drugs via Fas-dependent and Fas-independent pathways
36. Expression of Fas and anti-Fas-mediated apoptosis in human hepatocellular carcinoma cell lines
37. Wild-type human p53 and a temperature-sensitive mutant induce Fas/APO-1 expression
38. Defective CD95/APO-1/Fas signal complex formation in the human autoimmune lymphoproliferative syndrome, type Ia
39. The lymphoproliferation mutation in Fas locally unfolds the Fas death domain
40. Somatic mutations in the death domain of the Fas (Apo-1/CD95) gene in gastric cancer
41. Mutations in the Fas antigen in patients with multiple myeloma
42. Somatic Fas mutations in non-Hodgkin's lymphoma: Association with extranodal disease and autoimmunity
43. NMR structure and mutagenesis of the Fas (APO-1/CD95) death domain
44. Metabolic inhibitors sensitize for CD95 (APO-1/Fas)-induced apoptosis by down-regulating Fas-associated death domain-like interleukin 1-converting enzyme inhibitory protein expression
45. FLICE-inhibitory protein expression during macrophage differentiation confers resistance to fas-mediated apoptosis
46. Modulation of caspase-8 and FLICE-inhibitory protein expression as a potential mechanism of Epstein-Barr virus tumorigenesis in Burkitt's lymphoma
47. The inhibitor of death receptor signaling, FLICE-inhibitory protein defines a new class of tumor progression factors
48. Inhibition of mitogen-activated kinase signaling sensitizes HeLa cells to Fas receptor-mediated apoptosis