Perspectives on emerging biomarkers for non-invasive assessment of embryo viability in assisted reproduction

Current Molecular Medicine

Volumn 10, Issue 2, 2010, Pages 206-215

  Aydiner, F ^a   Yetkin, C E ^a   Seli, E ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

ART; Assisted reproductive technologies; Embryo; In vitro fertilization; IVF; Metablomics; Non invasive

Indexed keywords

AMINO ACID; BIOLOGICAL MARKER; GLUCOSE; LACTIC ACID; LEUKOCYTE ANTIGEN; OXYGEN; PYRUVIC ACID; TRANSCRIPTOME;

BLASTOCYTE; CULTURE MEDIUM; EMBRYO; EMBRYO TRANSFER; FEMALE INFERTILITY; FETUS DEVELOPMENT; GENOMICS; HUMAN; INFERTILITY THERAPY; MALE INFERTILITY; METABOLOME; METABOLOMICS; OXYGEN CONSUMPTION; PRENATAL DEVELOPMENT; PROTEOMICS; REPRODUCTION; REVIEW; ZYGOTE;

BIOLOGICAL MARKERS; EMBRYO CULTURE TECHNIQUES; EMBRYO IMPLANTATION; FEMALE; FERTILIZATION IN VITRO; GENOMICS; HUMANS; MALE; METABOLOMICS; OXYGEN CONSUMPTION; PREGNANCY; PREGNANCY RATE; PROTEOMICS; REPRODUCTIVE TECHNIQUES, ASSISTED;

EID: 77951053008     PISSN: 15665240     EISSN: None     Source Type: Journal    
DOI: 10.2174/156652410790963349     Document Type: Review

References (115)

1. Mosher, W.D. and Pratt, W.F. (1991) Fertil. Steril., 56, 192-193.
2. SART (2006). Centers for disease control, USA.
3. Rossi-Ferragut, L.M., Iaconelli, A., Jr., Aoki, T., Rocha, C.C., dos Santos, D.R., Pasqualotto, F.F. and Borges, E., Jr. (2003) J. Assist. Reprod. Genet., 20, 1-7.
4. Steptoe, P.C. and Edwards, R.G. (1978) Lancet, 2, 366.
5. Trounson, A., Leeton, J., Wood, C., Webb, J. and Wood, J. (1981) Science, 216, 681-682.
6. Wright, V.C., Chang, J., Jeng, G. and Macaluso, M. (2006) MMWR. Surveil. Summ., 55, 1-22.
7. Reddy, U.M., Wapner, R.J., Rebar, R.W. and Tasca, R.J. (2007) Obstet. Gynecol., 109, 967-977.
8. Bromer, J.G. and Seli, E. (2008) Curr. Opin. Obstet. Gynecol., 20, 234-241.
9. Bromer, J.G. and Seli, E. Preterm deliveries that result from ART-associated multiple pregnancies in the United States: A cost analysis. In 64th annual meeting of American Society of Reproductive Medicine. San Francisco, CA.
10. Luke, B. and Brown, M.B. (2007) Fertil. Steril., 88, 283-293.
11. Edwards, R.G., Fishel, S.B., Cohen, J., Fehilly, C.B., Purdy, J.M., Slater, J.M., Steptoe, P.C. and Webster, J.M. (1984) J. In Vitro Fert. Embryo Transf., 1, 3-23.
12. Gardner, D.K. and Schoolcraft, W.B., in Towards Reprodcutive Certainty: Fertility and Genetics Beyond (1999) In vitro culture of human blastocysts., Carnforth: Parthenon Publishing. 378-388.
13. Gerris, J., De Neubourg, D., Mangelschots, K., Van Royen, E., Van de Meerssche, M. and Valkenburg, M. (1999) Hum. Reprod., 14, 2581-2587.
14. Scott, L.A. and Smith, S. (1998) Hum. Reprod., 13, 1003-1013.
15. Tesarik, J. and Greco, E. (1999) Hum. Reprod., 14, 1318-1323.
16. VanRoyan, E., Mangelschots, K., De Neubourg, D., Valkenburg, M., Van de Meerssche, M., Ryckaert, G., Eestermens, W. and Gerris, J. (1999) Hum. Reprod., 14, 2345-2349.
17. Veeck, L. Ed. An Atlas of Human Gametes and Conceptuses: An Illustrated Reference for Assisted Reproductive Technology. (1999) ed. Vol.: Parthenon Publishing, New York, USA.
18. Toner, J.P. (2002) Fertil. Steril., 78, 943-950.
19. James, A.N. In Human Preimplantation Embryo Selection (2007) Human pronuclei as a mode of predicting viability, Published by CRC Press, 2007: London, U.K. pp. 31-40.
20. Kahraman, S., Kumtepe, Y., Sertyel, S., Donmez, E., Benkhalifa, M., Findikli, N. and Vanderzwalmen, P. (2002) Hum. Reprod., 17, 3193-3200.
21. Ludwig, M., Schopper, B., Katalinic, A., Sturm, R., Al-Hasani, S. and Diedrich, K. (2000) Hum. Reprod., 15, 319-324.
22. Scott, L. (2003) Reprod. BioMed. Online, 6, 201-214.
23. Scott, L., Alvero, R., Leondires, M. and Miller, B. (2000) Hum. Reprod., 15, 2394-2403.
24. Senn, A., Urner, F., Chanson, A., Primi, M.P., Wirthner, D. and Germond, M. (2006) Hum. Reprod., 21, 234-239.
25. Tesarik, J. and Greco, E. (1999) Hum. Reprod., 14, 1318-1323.
26. Tesarik, J., Junca, A.M., Hazout, A., Aubriot, F.X., Nathan, C., Cohen-Bacrie, P. and Dumont-Hassan, M. (2000) Hum. Reprod., 15, 1396-1399.
27. Zollner, U., Zollner, K.P., Hartl, G., Dietl, J. and Steck, T. (2002) Hum. Reprod., 17, 1327-1333.
28. Balaban, B., Urman, B., Isiklar, A., Alatas, C., Aksoy, S., Mercan, R., Mumcu, A. and Nuhoglu, A. (2001) Hum. Reprod., 16, 2357-2361.
29. Rienzi, L., Ubaldi, F., Iacobelli, M., Ferrero, S., Minasi, M.G., Martinez, F., Tesarik, J. and Greco, E. (2002) Hum. Reprod., 17, 1852-1855.
30. Ludwig, M., Schopper, B., Al-Hasani, S. and Diedrich, K. (2000) Hum. Reprod., 15, 325-329.
31. Payne, D., Flaherty, S.P., Barry, M.F. and Matthews, C.D. (1997) Hum. Reprod., 12, 532-541.
32. Scott, L. (2003) Hum. Reprod. Update, 9, 237-249.
33. Wittemer, C., Bettahar-Lebugle, K., Ohl, J., Rongieres, C., Nisand, I. and Gerlinger, P. (2000) Hum. Reprod., 15, 2591-2597.
34. Gamiz, P., Rubio, C., de los Santos, M.J., Mercader, A., Simon, C., Remohi, J. and Pellicer, A. (2003) Hum. Reprod., 18, 2413-2419.
35. Gianaroli, L., Magli, M.C., Ferraretti, A.P., Fortini, D. and Grieco, N. (2003) Fertil. Steril., 80, 341-349.
36. Manor, D., Drugan, A., Stein, D., Pillar, M. and Itskovitz-Eldor, J. (1999) J. Assist. Reprod. Genet., 16, 385-389.
37. Munne, S. and Cohen, J. (1993) Hum. Reprod., 8, 1120-1125.
38. Sadowy, S., Tomkin, G., Munne, S., Ferrara-Congedo, T. and Cohen, J. (1998) Zygote, 6, 137-141.
39. Lan, K.C., Huang, F.J., Lin, Y.C., Kung, F.T., Hsieh, C.H., Huang, H.W., Tan, P.H. and Chang, S.Y. (2003) Hum. Reprod., 18, 1299-1306.
40. Nagy, Z.P., Dozortsev, D., Diamond, M., Rienzi, L., Ubaldi, F., Abdelmassih, R. and Greco, E. (2003) Fertil. Steril., 80, 67-74.
41. De Neubourg, D., Gerris, J., Mangelschots, K., Van Royen, E., Vercruyssen, M. and Elseviers, M. (2004) Hum. Reprod., 19, 1476-1479.
42. Gardner, D.K., Stevens, J., Sheehan, C.B. and Schoolcraft, W.B., In Human Preimplantation Embryo Selection (2007) Analysis of Blastocyst Morphology, CRC Press, London, U.K. pp. 79-89.
43. Gardner, D.K., Schoolcraft, W.B., Wagley, L., Schlenker, T., Stevens, J. and Hesla, J. (1998) Hum. Reprod., 13, 3434-3440.
44. Behr, B., Pool, T.B., Milki, A.A., Moore, D., Gebhardt, J. and Dasig, D. (1999) Hum. Reprod., 14, 454-457.
45. Van der Auwera, I., Debrock, S., Spiessens, C., Afschrift, H., Bakelants, E., Meuleman, C., Meeuwis, L. and D'Hooghe, T.M. (2002) Hum. Reprod., 17, 1507-1512.
46. Gardner, D.K., Lane, M., Stevens, J., Schlenker, T. and Schoolcraft, W.B. (2000) Fertil. Steril., 73, 1155-1158.
47. Gardner, D.K., Surrey, E., Minjarez, D., Leitz, A., Stevens, J. and Schoolcraft, W.B. (2004) Fertil. Steril., 81, 551-555.
48. Sakkas, D. and Gardner, D.K. (2005) Curr. Opin. Obstet. Gynecol., 17, 283-288.
49. Gerris, J., De Neubourg, D., Mangelschots, K., Van Royen, E., Vercruyssen, M., Barudy-Vasquez, J., Valkenburg, M. and Ryckaert, G. (2002) Hum. Reprod., 17, 2626-2631.
50. Fisch, J.D., Rodriguez, H., Ross, R., Overby, G. and Sher, G. (2001) Hum. Reprod., 16, 1970-1975.
51. Neuber, E., Rinaudo, P., Trimarchi, J.R. and Sakkas, D. (2003) Hum. Reprod., 18, 1307-1312.
52. Leese, H.J. (1995) Hum. Reprod. Update, 1, 63-72.
53. Biggers, J.D., Whittingham, D.G. and Donahue, R.P. (1967) Proc. Nat.l Acad. Sci. USA, 58, 560-567.
54. Gardner, D.K. and Leese, H.J. (1988) Development, 104, 423-429.
55. Gott, A.L., Hardy, K., Winston, R.M. and Leese, H. J. (1990) Hum. Reprod., 5, 104-108.
56. Conaghan, J., Hardy, K., Handyside, A., Winston, R.M.L. and Leese, H.J. (1993) J. Assist. Reprod. Genet., 10, 21-30.
57. Conaghan, J., Handyside, A.H., Winston, R.M. and Leese, H.J. (1993) J. Reprod. Fertil., 99, 87-95.
58. Gardner, D.K., Lane, M., Stevens, J. and Schoolcraft, W. B. (2001) Fertil. Steril., 76, 1175-1180.
59. Hardy, K., Hooper, M.A.K., Handyside, A.H., Rutherford, A.J., Winston, R.M.L. and Leese, H.J. (1989) Hum. Reprod., 4, 188-191.
60. Leese, H.J. and Barton, A.M. (1984) J. Reprod. Fertil., 72, 9-13.
61. Brison, D.R. and Leese, H.J. (1991) J. Reprod. Fertil., 93, 245-251.
62. Gardner, D.K., Lane, M., Calderon, I. and Leeton, J. (1996) Fertil. Steril., 65, 349-353.
63. Hardy, K., Handyside, A. H. and Winston, R. M. (1989) Development, 107, 597-604.
64. Leese, H.J., Tay, J.I., Reischl, J. and Downing, S.J. (2001) Reproduction, 121, 339-346.
65. Gardner, D.K. and Lane, M. (1997) Hum. Reprod. Update, 3, 367-382.
66. Bavister, B.D. (1995) Hum. Reprod. Update, 1, 91-148.
67. Van der Ven, K., Montag, M., Peschka, B., Leygraaf, J., Schwanitz, G., Haidl, G., Krebs, D. and Van der Ven, H. (1997) Mol. Hum. Reprod., 3, 699-704.
68. Gott, A.L., Hardy, K., Winston, R.M. L. and Leese, H.J. (1990) Hum. Reprod., 5, 104-108.
69. Turner, K., Martin, K.L., Woodward, B.J., Lenton, E.A. and Leese, H.J. (1994) Hum. Reprod., 2362-2366.
70. Devreker, F., in Human Preimplantation Embryo Selection. (2007) Uptake and release of metabolites in human preimplantation embryos, Taylor and Francis: London, UK. pp. 325-336.
71. Renard, J. P., Phillippon, A. and Menezo, Y. (1980) J. Reprod. Fertil., 58, 161-164.
72. Gardner, D.K. and Leese, H.J. (1987) J. Exp. Zool., 242, 103-105.
73. Jones, G.M., Trounson, A.O., Vella, P.J., Thouas, G.A., Lolatgis, N. and Wood, C. (2001) Reprod. Biomed. Online, 3, 124-132.
74. Urbanski, J.P., Johnson, M.T., Craig, D.D., Potter, D.L., Gardner, D.K. and Thorsen, T. (2008) Anal. Chem., 80, 6500-6507.
75. Houghton, F.D., Hawkhead, J.A., Humpherson, P.G., Hogg, J.E., Balen, A.H., Rutherford, A.J. and Leese, H. J. (2002) Hum. Reprod., 17, 999-1005.
76. Leese, H.J., Baumann, C.G., Brison, D.R., McEvoy, T.G. and Sturmey, R.G. (2008) Mol. Hum. Reprod., 14, 667-672.
77. Brison, D.R., Houghton, F.D., Falconer, D., Roberts, S.A., Hawkhead, J., Humpherson, P.G., Lieberman, B.A. and Leese, H.J. (2004) Hum. Reprod., 19, 2319-2324.
78. Seli, E., Botros, L., Sakkas, D. and Burns, D.H. (2008) Fertil. Steril., 90, 2183-2189.
79. Trimarchi, J.R., Liu, L., Porterfield, D.M., Smith, P.J. and Keefe, D.L. (2000) Biol. Reprod., 62, 1866-1874.
80. Houghton, F.D., Thompson, J.G., Kennedy, C.J. and Leese, H.J. (1996) Mol. Reprod. Dev., 44, 476-485.
81. Magnusson, C., Hillensjo, T., Hamberger, L. and Nilsson, L. (1986) Hum. Reprod., 1, 183-184.
82. Shiku, H., Shiraishi, T., Ohya, H., Matsue, T., Abe, H., Hoshi, H. and Kobayashi, M. (2001) Anal. Chem., 73, 3751-3758.
83. Thompson, J.G., Partridge, R.J., Houghton, F.D., Cox, C.I. and Leese, H.J. (1996) J. Reprod. Fertil, 106, 299-306.
84. Lopes, A.S., Larsen, L.H., Ramsing, N., Lovendahl, P., Raty, M., Peippo, J., Greve, T. and Callesen, H. (2005) Reproduction, 130, 669-679.
85. Lopes, A.S., Madsen, S.E., Ramsing, N.B., Lovendahl, P., Greve, T. and Callesen, H. (2007) Hum. Reprod., 22, 558-566.
86. Lopes, A.S., Wrenzycki, C., Ramsing, N.B., Herrmann, D., Niemann, H., Lovendahl, P., Greve, T. and Callesen, H. (2007) Theriogenology, 68, 223-236.
87. Agung, B., Otoi, T., Abe, H., Hoshi, H., Murakami, M., Karja, N.W., Murakami, M.K., Wongsrikeao, P., Watari, H. and Suzuki, T. (2005) Reprod. Domest. Anim., 40, 51-56.
88. Abe H, and Hoshi, H. (2003) J. Reprod. Dev., 49, 193-202.
89. Houghton, F.D. (2006) Differentiation, 74, 11-18.
90. Fisch, J.D., Keskintepe, L. and Sher, G., in Human Preimplantation Embryo Selection (2007) Assesment of human leukocyte antigen G in human embryos, CRC Press, 2007: London, U.K. 145-154.
91. Jurisicova, A., Casper, R.F., MacLusky, N.J., Mills, G.B. and Librach, C.L. (1996) Proc. Natl Acad. Sci. USA, 93, 161-165.
92. Menicucci, A., Noci, I., Fuzzi, B., Criscuoli, L., Scarselli, G., Baricordi, O. and Mattiuz, P.L. (1999) Hum. Immunol., 60, 1054-1057.
93. Fuzzi, B., Rizzo, R., Criscuoli, L., Noci, I., Melchiorri, L., Scarselli, B., Bencini, E., Menicucci, A. and Baricordi, O.R. (2002) Eur. J. Immunol., 32, 311-315.
94. Sher, G., Keskintepe, L., Nouriani, M. and al., e. (2004) Reprod. Biomed. Online, 9, 74-78.
95. Sher, G., Keskintepe, L., Fisch, J.D., Acacio, B.A., Ahlering, P., Batzofin, J. and Ginsburg, M. (2005) Fertil. Steril., 83, 1410-1413.
96. Sher, G., Keskintepe, L., Batzofin, J., Fisch, J., Acacio, B., Ahlering, P. and Ginsburg, M. (2005) Hum. Reprod., 20, 1359-1363.
97. Noci, I., Fuzzi, B., Rizzo, R., Melchiori, L., Criscuoli, L., Dabizzi, S., Biagiotti, R., Pellegrini, S., Menicucci, A. and Baricordi O.R. (2005) Hum. Reprod., 20, 138-146.
98. Vercammen, M.J., Verloes, A., Van de Velde, H. and Haentjens, P. (2008) Hum. Reprod. Update, 14, 209-218.
99. Criscuoli, L., Rizzo, R., Fuzzi, B., Melchiorri, L., Menicucci, A., Cozzi, C., Dabizzi, S., Branconi, F., Evangelisti, P., Baricordi, O.R. and Noci, I. (2005) Gynecol. Endocrinol., 20, 264-269.
100. Yie, S.M., Balakier, H., Motamedi, G. and Librach, C.L. (2005) Fertil. Steril., 83, 30-36.
101. Desai, N., Filipovits, J. and Goldfarb, J. (2006) Reprod. BioMed. Online, 13, 272-277.
102. Fisch, J.D., Keskintepe, L., Ginsburg, M., Adamowicz, M. and Sher, G. (2007) Fertil. Steril., 87, 757-763.
103. Rebmann, V., Switala, M., Eue, I., Schwahn, E., Merzenich, M. and Grosse-Wilde, H. (2007) Hum. Immunol., 68, 251-258.
104. Sageshima, N., Shobu, T., Awai, K., Hashimoto, H., Yamashita, M., Takeda, N., Odawara, Y., Nakanishi, M., Hatake, K. and Ishitani, A. (2007) J. Reprod. Immunol., 75, 11-22.
105. Katz-Jaffe, M.G., Gardner, D.K. and Schoolcraft, W.B. (2006) Fertil. Steril., 85, 101-107.
106. Katz-Jaffe, M.G., Linck, D.W., Schoolcraft, W.B. and Gardner, D.K. (2005) Reproduction, 130, 899-905.
107. Katz-Jaffe, M. G., Schoolcraft, W. B. and Gardner, D. K. (2006) Fertil. Steril., 86, 678-685.
108. Posillico, J. T., in Human Preimplantation Embryo Selection (2007) Selection of viable embryos and gametes by rapid, non-invasive metabolomic profiling of oxidative stress biomarkers, Informa Ltd.: London, U.K. 245-262.
109. Botros, L., Sakkas, D., Seli E. (2009) Mol. Hum. Reprod., 14, 679-690.
110. Niranjanakumari, S., Lasda, E., Brazas, R. and Garcia- Blanco, M. A. (2002) Methods, 26, 182-190.
111. Seli, E., Sakkas, D., Scott, R., Kwok, J. S., Rosendahl, S. and Burns, D. H. (2007) Fertil. Steril., 88, 1350-1357.
112. Scott, R. T., Seli, E., Miller, K., Sakkas D, Scott, K. and Burns, D. H. (2008) Fertil. Steril., 90, 77-83.
113. Vergouw, C. G., Botros, L. L., Roos, P., Lens, J. W., Schats, R., Hompes, P. G. A., Burns, D. H. and Lambalk, C. B. (2008) Hum. Reprod., 23, 1499-1504,
114. Seli, E., Vergouw, C.G., Kato, O., Botros, L., Roos, P., Morita, H., Lambalk, C.B., Yamashita, N. and Sakkas, D. (2009) Fertil. Steril., [Epub July 7, 2009].
115. Hardarson, T., Tucker, M., Seli, E., Botros, L., Roos, P. and Sakkas, D. (2008) Non-invasive metabolic profiling of day 5 embryo culture media adds to the discriminatory power of blastocyst culture for Single Embryo Transfer (SET). in American Society for Reproductive Medicine. San Fransisco, CA.