The predictive value of using a combined Z-score and day 3 embryo morphology score in the assessment of embryo survival on day 5

Human Reproduction

Volumn 18, Issue 6, 2003, Pages 1299-1306

  Lan, Kuo Chung ^a   Huang, Fu Jen ^a,b   Lin, Yi Chi ^a   Kung, Fu Tsai ^a,b   Hsieh, Chin Hsiung ^a   Huang, Hsuan Wei ^a   Tan, Ping Heng ^a   Chang, Shiuh Young ^a,b  

^a CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

^b CHANG GUNG UNIVERSITY   (Taiwan)

Author keywords

Embryo morphology; Embryo survival; Embryo transfer; Implantation; Zygote scoring

Indexed keywords

CHORIONIC GONADOTROPIN; LEUPRORELIN; PROGESTERONE; RECOMBINANT FOLLITROPIN;

ADULT; ARTICLE; BLASTOCYST; COHORT ANALYSIS; CONCEPTION; CONTROLLED STUDY; DRUG DOSE REDUCTION; EMBRYO CULTURE; EMBRYO DEVELOPMENT; EMBRYO TRANSFER; FEMALE; FERTILIZATION IN VITRO; FOLLOW UP; HUMAN; INFERTILITY; INTRACYTOPLASMIC SPERM INJECTION; MAJOR CLINICAL STUDY; MALE; MORPHOLOGY; MULTIPLE PREGNANCY; NIDATION; OVARY HYPERSTIMULATION; OVULATION INDUCTION; PREDICTION; PREGNANCY RATE; RETROSPECTIVE STUDY; RISK MANAGEMENT; SCORING SYSTEM; STATISTICAL ANALYSIS; SURVIVAL; TREATMENT OUTCOME; ZYGOTE;

EID: 0037731654     PISSN: 02681161     EISSN: None     Source Type: Journal    
DOI: 10.1093/humrep/deg239     Document Type: Article

References (37)

1. Chang, S.Y., Lee, C.L., Wang, M.L., Hu, M.L., Lai, Y.M., Chang, M.Y. and Soong, Y.K. (1993) No detrimental effects in delaying initiation of gonadotrophin administration after pituitary desensitization with gonadotrophin-releasing hormone agonist. Fertil. Steril., 59, 183-186.
2. Coskun, S., Hollanders, J., Al-Hassan, S., Al-Sufyan, H., Al-Mayman, H. and Jaroudi, K. (2000) Day 5 versus day 3 embryo transfer: A controlled randomized trial. Hum. Reprod., 15, 1947-1952.
3. Cox, D.R. (1972) Regression models and life tables. J. R. Statist. Soc. B., 34, 187-220.
4. Fisch, J.D., Rodriguez, H., Ross, R., Overby, G. and Sher, G. (2001) The Graduated Embryo Score (GES) predicts blastocyst formation and pregnancy rate from cleavage-stage embryos. Hum. Reprod., 16, 1970-1975.
5. Garcia-Velasco, J.A. and Simon, C. (2001) Blastocyst transfer: Does it really affect the outcome? Curr. Opin. Obstet. Gynecol., 13, 299-304.
6. Gardner, D.K., Schoolcraft, W.B., Wagley, L., Schlenker, T., Stevens, J. and Hesla, J. (1998) A prospective randomized trial of blastocyst culture and transfer in in vitro fertilization. Hum. Reprod., 13, 3434-3440.
7. Gardner, D.K., Schoolcraft, W.B., Jansen, R. and Mortimer, D. (eds) (1999) In vitro culture of human blastocysts. In Towards Reproductive Certainty: Infertility and Genetics Beyond. Parthenon Press, Carnforth, UK. pp. 378.
8. Gardner, D.K., Lane, M., Stevens, J., Schlenker, T. and Schoolcraft, W.B. (2000) Blastocyst score affects implantation and pregnancy outcome: Towards a single blastocyst transfer. Fertil. Steril., 73, 1155-1158
9. Graham, J., Han, T., Porter, R., Levy, M., Stillman, R. and Tucker, M.J. (2000) Day 3 morphology is a poor predictor of blastocyst quality in extended culture. Fertil. Steril., 74, 495-497.
10. Hardy, K., Spanos, S., Becker, D., Iannelli, P., Winston, R.M. and Stark, J. (2001) From cell death to embryo arrest: Mathematical models of human pre-implantation embryo development. Proc. Natl Acad. Sci. USA, 98, 1655-1660.
11. Hernandez, E.R. (2001) Avoiding multiple pregnancies: Sailing uncharted seas. Hum. Reprod., 6, 615-616.
12. Hsu, M.I., Mayer, J., Aronshon, M., Lanzendorf, S., Muasher, S., Kolm, P. and Oehninger, S. (1999) Embryo implantation in in vitro fertilization and intracytoplasmic sperm injection: Impact of cleavage status, morphology grade, and number of embryos transferred. Fertil. Steril., 72, 679-685.
13. Hunault, C.C., Eijkemans, M.J., Pieters, M.H., Te Velde, E.R., Habbema, J.D., Fauser, B.C. and Macklon, N.S. (2002) A prediction model for selecting patients undergoing in vitro fertilization for elective single embryo transfer. Fertil. Steril., 77, 725-732.
14. Kaplan, E.S. and Meier, P. (1958) Nonparametric estimation from incomplete observations. J. Am. Stat. Assoc., 53, 457-461.
15. Lan, K.C., Lin, Y.C., Huang, F.J., Kung, F.T., Hsieh, C.H. and Chang, S.Y. (2002) Comparison of metaphase II oocytes after stimulation with recombinant follicle-stimulating hormone and urinary follicle-stimulating hormone in a pituitary down-regulation regimen. Fertil. Steril., 78, 639-641.
16. Ludwig, M., Schopper, B., Al-Hasani, S. and Diedrich, K. (2000) Clinical use of a pronuclear stage score following intracytoplasmic sperm injection: Impact on pregnancy rates under the conditions of the German embryo protection law. Hum. Reprod., 15, 325-329.
17. Milki, A.A., Hinckley, M.D., Gebhardt, J., Dasig, D., Westphal, L.M. and Behr, B. (2002) Accuracy of day-3 criteria for selecting the best embryos. Fertil. Steril., 77, 1191-1195.
18. Montag, M. and Van Der Ven, H. for the German Pronuclear Morphology Study Group (2001) Evaluation of pronuclear morphology as the only selection criterion for further embryo culture and transfer: Results of a prospective multicentre study. Hum. Reprod., 16, 2384-2389.
19. Palermo, G., Joris, H., Devroey, P. and Van Steirteghem, A.C. (1992) Pregnancies after intracytoplasmic injection of single spermatozoon into an oocyte. Lancet, 340, 17-18.
20. Payne, D., Flaherty S.P., Barry, M.F. and Matthews, C.D. (1997) Preliminary observations on polar body extrusion and pronuclear formation in human oocytes using time-lapse video cinematography Hum. Reprod., 12, 532-541.
21. Puissant, F., Van Rysselberg, M., Barlow, P., Deweze, J. and Leroy, F. (1987) Embryo scoring as a prognostic tool in IVF treatment. Hum. Reprod., 2, 705-708.
22. Racowsky, C., Jackson, K.V., Cekleniak, N.A., Fox, J.H., Hornstein, M.D. and Ginsburg, E.S. (2000) The number of eight-cell embryos is a key determinant for selecting day-3 or day-5 transfer. Fertil. Steril., 73, 558-564.
23. Rienzi, L., Ubaldi, F., Iacobelli, M., Ferrero, S., Minasi, M.G., Martinez, F., Tesarik, J. and Greco, E. (2002) Day-3 embryo transfer with combined evaluation at the pronuclear and cleavage stages compares favourably with day-5 blastocyst transfer. Hum. Reprod., 17, 1852-1855.
24. Rijnders, P.M. and Jansen, C.A.M. (1998) The predictive value of day-3 embryo morphology regarding blastocyst formation, pregnancy and implantation rate after day-5 transfer following in vitro fertilization or intracytoplasmic sperm injection. Hum. Reprod., 13, 2869-2873.
25. Rosner, B. (2000) The treatment of censored data. In Fundamentals of Biostatistics, 5th edn. Duxbury, California, pp. 715-771.
26. Sakkas, D. (2001) Reflections on the number of embryos to replace at the dawn of the 21st century. Curr. Opin. Obstet. Gynecol., 13, 293-297.
27. Schieve, L.A., Meikle, S.F., Ferre, C., Peterson, H.B., Jeng, G. and Wilcox, L.S. (2002) Low and very low birth weight in infants conceived with use of assisted reproductive technology. N. Engl. J. Med., 346, 731-737.
28. Scott, L.A. and Smith, S. (1998) The successful use of pronuclear embryo transfers the day following oocyte retrieval. Hum. Reprod., 13, 1003-1013.
29. Scott, L., Alvero, R., Leondires, M. and Miller, B. (2000) The morphology of human pronuclear embryos is positively related to blastocyst development and implantation. Hum. Reprod., 15, 2394-2403.
30. Shoukir, Y., Campana, A., Farley, T. and Sakkas, D. (1997) Early cleavage of in-vitro fertilized human embryos to the 2-cell stage: A novel indicator of embryo quality and viability. Hum. Reprod., 12, 1531-1536.
31. Tesarik, J. and Greco, E. (1999) The probability of abnormal pre-implantation development can be predicted by a single static observation on pronuclear stage morphology. Hum. Reprod., 14, 1318-1323.
32. Toledo, A.A., Wright, G., Jones, A.E., Smith, S.S., Johnson-Ward, J., Bockman, W.W., Ng, F. and Wininger, J.D. (2000) Blastocyst transfer: A useful tool for reduction of high-order multiple gestations in a human assisted reproduction program. Am. J. Obstet. Gynecol., 183, 377-379; discussion 380-382.
33. Tsai, M.Y., Huang, F.J., Kung, F.T., Lin, Y.C., Chang, S.Y., Wu, J.F. and Chang, H.W. (2000) Influence of polyvinylpyrrolidone on the outcome of intracytoplasmic sperm injection. J. Reprod. Med., 45, 115-120.
34. Van Royen, E., Mangelschots, K., De Neubourg, D., Valkenburg, M., Van De Meerssche, M., Ryckaert, G., Eestermans, W. and Gerris, J. (1999) Characterization of a top-quality embryo, a step towards single-embryo transfer. Hum. Reprod., 14, 2345-2349.
35. Veeck, L.L. (1986) Atlas of the Human Oocyte and Early Conceptus. Williams & Wilkins, Baltimore, pp. 314.
36. Wittemer, C., Bettahar-Lebugle, K., Ohl, J., Rongieres, C., Nisand, I. and Gerlinger, P. (2000) Zygote evaluation: An efficient tool for embryo selection. Hum. Reprod., 15, 2591-2597.
37. Zollner, U., Zollner, K.P., Hartl, G., Dietl, J. and Steck, T. (2002) The use of a detailed zygote score after IVF/ICSI to obtain good quality blastocysts: The German experience. Hum. Reprod., 17, 1327-1333.