Pronuclear and morphological features as a cumulative score to select embryos in ICSI (Intracytoplasmic Sperm Injection) cycles according to sperm origin

Journal of Assisted Reproduction and Genetics

Volumn 20, Issue 1, 2003, Pages 1-7

  Rossi Ferragut, Lia Mara ^a   Iaconelli Jr , Assumpto ^a   Aoki, Tsutomu ^a   Chagas Rocha, Claudia ^a   Dos Santos, Daniela Regina ^a   Firmbach Pasqualotto, Fábio ^b   Borges Jr , Edson ^a  

^a Fertility Assisted Fertilization Center   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Embryo selection; ICSI; Morphological features; PN morphology; Sperm origin

Indexed keywords

ADULT; ARTICLE; AZOOSPERMIA; CHI SQUARE TEST; CLASSIFICATION; CONTROLLED STUDY; EJACULATION; EMBRYO; EMBRYO (ANATOMY); EMBRYO CULTURE; EMBRYO TRANSFER; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; INFERTILITY; INTRACYTOPLASMIC SPERM INJECTION; MAJOR CLINICAL STUDY; MALE; MORPHOLOGICAL TRAIT; NIDATION; NUCLEOLUS; OLIGOSPERMIA; OOCYTE; PREGNANCY; PRIORITY JOURNAL; PRONUCLEUS; QUALITY CONTROL; SCORING SYSTEM; SPERM DONOR; SPERMATOZOON COUNT; SPONTANEOUS ABORTION; STATISTICAL ANALYSIS; STUDENT T TEST; ZYGOTE;

ABORTION, SPONTANEOUS; CELL NUCLEOLUS; CLEAVAGE STAGE, OVUM; EJACULATION; EMBRYO IMPLANTATION; EMBRYO TRANSFER; EPIDIDYMIS; FEMALE; HUMANS; MALE; OLIGOSPERMIA; PREGNANCY; PREGNANCY RATE; SPERM INJECTIONS, INTRACYTOPLASMIC; SPERMATOZOA; TESTIS; ZYGOTE;

EID: 0037278365     PISSN: 10580468     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1021286119979     Document Type: Article

References (35)

1. Balakier H, MacLusky NJ, Casper RF: Characterization of the first cell cycle in human zygotes: Implications for cryopreservation. Fertil Steril 1993;59:359-365
2. Staessen C, Janssenswillen C, van den Abbeel E, Devroey P, Van Steirteghem AC: Avoidance of triplet pregnancies by elective transfer of two good quality embryos. Hum Reprod 1993;8:1650-1653
3. Xia P: Intracytoplasmic sperm injection: Correlation of oocyte grade based on polar body, perivitelline space and cytoplasmic inclusions with fertilization rate and embryo quality. Hum Reprod 2000;12:1750-1755
4. Tesarik J, Junca AM, Hazout A, et al.: Embryos with high implantation potential after intracytoplasmic sperm injection can be recognized by a simple, non-invasive examination of pronuclear morphology. Hum Reprod 2000;15(6):1396-1399
5. Handarson T, Hanson C, Sjogren A, Lundin K: Human embryos with unevenly sized blastomeres have lower pregnancy and implantation rates: Indications for aneuploidy and multinucleation. Hum Reprod 2001;16(2):313-318
6. Fasolino A, Longo V, Capece G, et al.: Evaluation of oocyte maturity in patients undergoing ICSI and R-FSH treatment. Minerva Ginecol 2001;53(3):157-163
7. Wright G, Wiker S, Elsner C, et al.: Observations on the morphology of pronuclei and nucleoli in human zygotes and implications for cryopreservation. Hum Reprod 1990;5:109-115
8. Scott LA, Smith S: The successful use of pronuclear embryo transfers the day following oocyte retrieval, Hum Reprod 1998;13(4):1003-1013
9. Tesarik J, Grecco E: The probability of abnormal preimplantation development can be predicted by a single static observation on pronuclear stage morphology. Hum Reprod 1999;14(5):1318-1323
10. Demirel LC, Evirgen O, Aydos K, Unlu C: The impact of the source of spermatozoa used for ICSI on pronuclear morphology. Hum Reprod 2001;16(11):2327-2332
11. Palermo G, Joris H, Devroey P, Van Steirteghem AC: Pregnancies after intracytoplasmic injection of single spermatozoon into an oocyte, Lancet 1992;340:17-18
12. Ebner T, Moser M, Yaman C, et al.: Elective transfer of embryos selected on the basis of first polar body morphology is associated with increased rates of implantation and pregnancy. Fertil Steril 1999;72(4):599-603
13. Garello C, Baker H, Rai J, et al.: Pronuclear orientation, polar body placement, and embryo quality after intracytoplasmic sperm injection and in-vitro fertilization: Further evidence for polarity in human oocytes. Hum Reprod 1999;14(10):2588-2595
14. Hsu MI, Mayer J, Aronshon M, et al.: Embryo implantation in vitro fertilization and intracytoplasmic sperm injection: Impact of cleavage status, morphology grade and number of embryos transferred, Fertil Steril 1999;72(4):679-685
15. Van Royen E, Mangelschots K, De Neubourg D, et al.: Characterization of a top quality embryo, a step towards single-embryo transfer. Hum Reprod 1999;14(9):2345-2349
16. Navot D, Bergh AB, Williams MA, et al.: Poor oocyte rather than implantation failure as a cause of age related decline in female fertility. Lancet 1991;337:1375-1377
17. Devroey P, Godoy H, Smitz J, et al.: Female age predicts embryonic implantation after ICSI: A case controlled study. Hum Reprod 1996;11:1324-1327
18. Adonakis G, Camus M, Joris H, et al.: The role of the number of replaced embryos on intracytoplasmic sperm injection outcome in women over the age of 40. Hum Reprod 1997;11:2542-2545
19. Osmanagaoglu K, Tournaye H, Kolibianakis E, et al.: Cumulative delivery rates after ICSI in women aged >37 years. Hum Reprod 2002;17(4):944-949
20. Kably AA, Carballo E, Karchmer KS: Gamete laboratory. Determining factors of success in in-vito fertilization. Ginecol Obstet Mex 2001;69:172-179
21. Mikkelsen AI, Lindenberg S: Morphology of in-vitro matured oocytes: Impact on fertility potential and embryo quality. Hum Reprod 2001;16(8):1714-1718
22. Kruger TF, Acosta AA, Simmons KF, et al.: Predictive value of abnormal sperm morphology in in vitro fertilization. Fertil Steril 1988;49:112-117
23. Ron-El R, Raziel A, Strassburger D, et al.: Outcome of assisted reproductive technology in women over the age of 41. Fertil Steril 2000;74:471-475
24. Borges E, Jr, Rossi-Ferragut LM, Rocha CC, Iaconelli A, Jr: Influence of sperm quality in ICSI (intracytoplasmic sperm injection) cycles outcomes. Braz J Urol 2001;27:P238
25. Steer CV, Mills CL, Tan SL, et al.: The cumulative embryo score: A predictive embryo scoring technique to select the optimal number of embryos to transfer in an in vitro fertilization and embryo transfer programme. Hum Reprod 1992;7:117-119
26. Ludwig M, Schopper B, Al-Hasani S, Diedrich K: Clinical use of a pronuclear stage score following intracytoplasmic sperm injection: Impact on pregnancy rates under the conditions of the German embryo protection law. Hum Reprod 2000;15(12):325-329
27. Lundqvist M, Johansson U, Lundkvvist O, et al.: Does pronuclear morphology and/or early cleavage rate predict embryo implantation potential? RBM on line 2001;2(1):12-16
28. Wittemer C, Bettahar-Lebugle K, Ohl J, et al.: Zygote evaluation: An efficient tool for embryo selection. Hum Reprod 2000;5(2):2591-2597
29. Pasqualotto FF, Rossi-Ferragut LM, Rocha CC, et al.: Outcome of in vitro fertilization and intracytoplasmic injection of epididymal and testicular sperm obtained from patients with obstructive and nonobstructive azoospermia. J Urol 2002;167:1753-1756
30. Schatten G: The centrosome and its mode of inheritance: The reduction of the centrosome during gametogenesis and its restoration during fertilization. Dev Biol 1984;165:2999-3335
31. Browder LW, Erickson CA, Jeffrey WR: Developmental Biology, 3rd edn. Philadelphia, Saunders, 1991
32. Sathananthan AH, Kola I, Truounson A, et al.: Centrioles in beginning of human development. Proc Natl Acad Sci 1991;88:4806-4810
33. Rossi-Ferragut LM, Iaconelli A, Aoki T, et al.: Zygote morphology scoring in male and female factor in ICSI cycles. Hum Reprod 2001;16(1);O-109,45, 17th Annual Meeting
34. Rocha CC, Iaconelli A, Rossi-Ferrragut LM, et al.: Clinical use of a pronuclear stage score following intracytoplasmic sperm injection (ICSI) compared with chromosomal status. Fertil Steril 2000;S175:P-252, 56th Annual Meeting of the American Society for Reproductive Medicine
35. Rossi-Ferragut LM, Iaconelli A, Rocha C, et al.: Relationships between pronuclei and nucleoli morphology with the prognosis in intracytoplasmic sperm injection (ICSI) cycles. Fertil Steril 2001;S124:P-38;57th Annual Meeting of the American Society for Reproductive Medicine