Starter Cultures: Bacteriophage

Cheese: Chemistry, Physics and Microbiology

Volumn 1, Issue C, 2004, Pages 163-189

  McGrath, S ^a   Fitzgerald, G F ^a   van Sinderen, D ^a  

^a UNIVERSITY COLLEGE CORK   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 77951023522     PISSN: 1874558X     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S1874-558X(04)80067-8     Document Type: Chapter

References (222)

1. II. Ackermann H.-W., and DuBow M.S. Viruses of Prokaryotes Vols I (1987), CRC Press, London
2. Alatossava T., and Klaenhammer T.R. Molecular characterization of three small isometric-headed bacteriophages which vary in their sensitivity to the lactococcal phage resistance plasmid pTR2030. Appl. Environ. Microbiol. 57 (1991) 1346-1353
3. Allison G.E., and Klaenhammer T.R. Phage resistance mechanisms in lactic acid bacteria. Int. Dairy J. 8 (1998) 207-226
4. Altermann E., Klein J.R., and Henrich B. Primary structure and features of the genome of the Lactobacillus gasseri temperate bacteriophage adh. Gene 236 (1999) 333-346
5. Anba J., Bidnenko E., Hillier A., Ehrlich D., and Chopin M.C. Characterization of the lactococcal abiDl gene coding for phage abortive infection. J. Bacteriol. 177 (1995) 3818-3823
6. Arendt E.K., Daly C., Fitzgerald G.E., and Van de Guchte M. Molecular characterisation of lactococcal bacteriophage Tuc2009 and identification and analysis of genes encoding lysin, a putative holin, and two structural proteins. Appl. Environ. Microbiol. 60 (1994) 1875-1883
7. Auad L., Peril M.A.A., Holgado A., and Raya R.R. Evidence of a restriction/modification system in Lactobacillus delbrueckii subsp. lactis CNRZ 326. Curr. Microbiol. 36 (1998) 271-273
8. Auvray E., Coddeville M., Ritzenthaler P., and Dupont L. Plasmid integration in a wide range of bacteria mediated by the integrase of Lactobacillus delbrueckii bacteriophage mv4. J. Bacteriol. 179 (1997) 1837-1845
9. Benbadis L., Faelen M., Slos P., Fazel A., and Mercenier A. Characterisation and comparison of virulent bacteriophages of Streptococcus thermophilus isolated from yoghurt. Biochimie 72 (1990) 855-862
10. Bickle T.A., and Kruger D.H. Biology of DNA restriction. Microbiol. Rev. 57 (1993) 434-450
11. Bidnenko E., Ehrlich S.D., and Chopin M.C. Phage operon involved in sensitivity to Lactococcus lactis abortive infection mechanism AbiDl. J. Bacteriol. 177 (1995) 3824-3829
12. Biswas B., Adhya S., Washart P., Paul B., Trostel A.N., Powell B., Carlton R., and Merril C.R. Bacteriophage therapy rescues mice bacteremic from a clinical isolate of vancomycin-resistant Enterococcus faecium. Infect. Immunol. 70 (2002) 204-210
13. Black L.W. DNA packaging in dsDNA bacteriophages. Ann. Rev. Microbiol. 43 (1989) 267-292
14. Blasi U., and Young R. Two beginnings for a single purpose: the dual start holins in the regulation of phage lysis. Mol. Microbiol. 21 (1996) 675-682
15. Bolotin A., Wincker P., Mauger S., Jaillon O., Malarme K., Weissenbach J., Ehrlich S.D., and Sorokin A. The complete genome sequence of the lactic acid bacterium Lactococcus lactis ssp. lactis IL1403. Genome Res. 11 (2001) 731-753
16. Botstein D. A theory of modular evolution for bacteriophages. Ann. NY Acad. Sci. 354 (1980) 484-491
17. Bouchard J.D., and Moineau S. Homologous recombination between a lactococcal bacteriophage and the chromosome of its host strain. Virology 270 (2000) 65-75
18. Bouchard J.D., Dion E., Bissonnette F., and Moineau S. Characterization of the two-component abortive phage infection mechanism AbiT from Lactococcus lactis. J Bacteriol 184 (2002) 6325-6332
19. Bourniquel A.A., Casey M.G., Mollet B., and Pridmore R.D. DNA sequence and functional analysis of Lactobacillus delbrueckii subsp. lactis plasmids pN42 and pJBL2. Plasmid 47 (2002) 153-157
20. Boyce J.D., Davison B.E., and Hillier A.J. Identification of prophage genes expressed in lysogens of the Lactococcus lactis bacteriophage BK5-T. Appl. Environ. Microbiol. 61 (1995) 4099-4104
21. Bradley D.E. A review: ultrastructure of bacteriophage and bacteriocins. Bacteriol Rev. 31 (1967) 230-314
22. Braun V., Hertwig S., Neve H., Geis A., and Teuber M. Taxonomic differentiation of bacteriophages of Lactococcus lactis by electron microscopy, DNA-DNA hybridisation, and protein profiles. J. Gen. Microbiol. 135 (1989) 2551-2560
23. Brondsted L., Ostergaard S., Pedersen M., Hammer K., and Vogensen F.K. Analysis of the complete DNA sequence of the temperate bacteriophage TP901-1: evolution, structure, and genome organization of lactococcal bacteriophages. Virology 283 (2001) 93-109
24. Brüssow H., and Desiere F. Comparative phage genomics and the evolution of Siphoviridae: insights from dairy phages. Mol. Microbiol 39 (2001) 213-222
25. Brüssow H., Frémont M., Bruttin A., Sidoti J., Constable A., and Fryder V. Detection and classification of Streptococcus thermophilus bacteriophages isolated from industrial milk fermentation. Appl. Environ. Microbiol. 60 (1994) 4537-4543
26. Brüssow H., Probst A., Frémont M., and Sidoti J. Distinct Streptococcus thermophilus bacteriophages share an extremely conserved DNA fragment. Virology 200 (1994) 854-857
27. Brüssow H., Bruttin A., Desiere F., Lucchini S., and Foley S. Molecular ecology and evolution of Streptococcus thermophilus bacteriophages - a review. Virus Gen. 16 (1998) 95-109
28. Bruttin A., Desiere E., Lucchini S., Foley S., and Brüssow H. Characterisation of the lysogeny DNA module from the temperate Streptococcus thermophilus bacteriophage Sfi21. Virology 223 (1997) 136-148
29. Budde-Niekiel A., and Teuber M. Electron microscopy of the adsorption of bacteriophages to lactic acid streptococci. Milchwissenschaft 42 (1987) 551-554
30. Burrus V., Bontemps C., Decaris B., and Guedon G. Characterization of a novel type II restriction-modification system, Sth368I, encoded by the integrative element ICEStl of Streptococcus thermophilus CNRZ368. Appl. Environ. Microbiol. 67 (2001) 1522-1528
31. Chandry P.S., Moore S.C., Davidson B.E., and Hillier A.J. Analysis of the cos region of the Lactococcus lactis bacteriophage ski. Gene 138 (1994) 123-126
32. Chandry P.S., Moore S.C., Boyce J.D., Davidson B.E., and Hillier A.J. Analysis of the DNA sequence, gene expression, origin of replication and modular structure of the Lactococcus lactis bacteriophage ski. Mol. Microbiol. 26 (1997) 49-64
33. Chopin A., Bolotin A., Sorokin A., Ehrlich S.D., and Chopin M.C. Analysis of six prophages in Lactococcus lactis IL1403: different genetic structure of temperate and virulent phage populations. Nucl Acids Res. 29 (2001) 644-651
34. Christiansen B., Johsen M.G., Stenby E., Vogensen F.K., and Hammer K. Characterization of the lactococcal temperate phage TP901-1 and its site specific integration. J. Bacteriol. 176 (1994) 1069-1076
35. Christiansen B., Brondsted L., Vogensen F.K., and Hammer K. A resolvase-like protein is required for the sitespecific integration of the temperate lactococcal bacteriophage TP901-1. J. Bacteriol 178 (1996) 5164-5173
36. Chung D.K., Kim J.K., and Batt C.A. Cloning and nucleotide sequences of the major capsid protein from Lactococcus lactis spp. cremoris bacteriophage F4-1. Gene 101 (1991) 121-125
37. Chung D.K., Chung S.K., and Batt C.A. Antisense RNA directed against the major capsid protein of Lactococcus lactis subsp. cremoris bacteriophage 4-1 confers partial resistance to the host. Appl. Microbiol. Biotechnol 37 (1992) 79-83
38. Cluzel P.J., Chopin A., Ehrlich S.D., and Chopin M.C. Phage abortive infection mechanism from Lactococcus lactis subsp. lactis, expression of which is mediated by an Iso-ISSl element. Appl. Environ. Microbiol. 57 (1991) 3547-3551
39. Coffey A., and Ross R.P. Bacteriophage-resistance systems in dairy starter strains: molecular analysis to application. Antonie van Leeuwenhoek 82 (2002) 303-321
40. General Aspects. Cogan T.M., and Hill C. Cheese starter cultures. In: Fox P.F. (Ed). Cheese: Chemistry, Physics and Microbiology Vol. 1 (1994), Elsevier, Boca Raton, FL 193-255
41. Coleman J., Green P.J., and Inouye M. The use of RNAs complementary to specific mRNAs to regulate the expression of individual bacterial genes. Cell 37 (1984) 429-436
42. Collins E.B. Host-controlled variations in bacteriophages active against lactic streptococci. Virology 9 (1956) 261-271
43. Cords B.R., McKay L.L., and Guerry P. Extrachromosomal elements in group N streptococci. J. Bacteriol. 117 (1974) 1149-1152
44. Crutz-Le Coq A.M., Cesselin B., Commissaire J., and Anba J. Sequence analysis of the lactococcal bacteriophage bIL170: insights into structural proteins and HNH endonucleases in dairy phages. Microbiology 148 (2002) 985-1001
45. Cruz Martin M., Alonso J.C., Suarez J.E., and Alvarez M.A. Generation of food-grade recombinant lactic acid bacterium strains by site-specific recombination. Appl. Environ. Microbiol 66 (2000) 2599-2604
46. d'Hérelle F. Sur un microbe invisible antagonistic des bacilles dysenteriques. CR Acad. Sci. Paris 165 (1917) 373-375
47. Dai G., Su P., Allison G.E., Geller B.L., Zhu P., Kim W.S., and Dunn N.W. Molecular characterization of a new abortive infection system (AbiU) from Lactococcus lactis LL51-1. Appl. Environ. Microbiol. 67 (2001) 5225-5232
48. Daly C., Fitzgerald G.F., and Davis R. Biotechnology of lactic acid bacteria with special reference to bacteriophage resistance. Antonie van Leeuwenhoek 70 (1996) 99-110
49. David M., Borasio G.D., and Kaufmann G. Bacteriophage T4-induced anticodon-loop nuclease detected in a host strain restrictive to RNA ligase mutants. Proc. Natl. Acad. Sci. USA 79 (1982) 7097-7101
50. Davidson B.E., Powell I.B., and Hillier A.J. Temperate bacteriophages and lysogeny in lactic acid bacteria. FEMS Microbiol. Rev. 87 (1990) 79-90
51. Davidson B.E., Kordias N., Dobos M., and Hillier A.J. Genomic organization of lactic acid bacteria. Antonie van Leeuwenhoek 70 (1996) 161-183
52. [published erratum appears in FEMS Microbiol. Lett. 1997; 148:273]. Deng Y.M., Harvey M.L., Liu C.Q., and Dunn N.W. A novel plasmid-encoded phage abortive infection system from Lactococcus lactis biovar. diacetylactis. FEMS Microbiol. Lett. 146 (1997) 149-154
53. Deng Y.M., Liu C.Q., and Dunn N.W. Genetic organization and functional analysis of a novel phage abortive infection system, AbiL, from Lactococcus lactis. J. Biotechnol. 67 (1999) 135-149
54. Deng Y.M., Liu C.Q., and Dunn N.W. LldI, a plasmid-encoded type I restriction and modification system in Lactococcus lactis. DNA Seq 11 (2000) 239-245
55. Desiere E., Lucchini S., and Brussow H. Evolution of Streptococcus thermophilus bacteriophage genomes by modular exchanges followed by point mutations and small deletions and insertions. Virology 241 (1998) 345-356
56. Desiere F., Lucchini S., and Brüssow H. Comparative sequence analysis of the DNA packaging, head, and tail morphogenesis modules in the temperate cos-site Streptococcus thermophilus bacteriophage Sfi21. Virology 260 (1999) 244-253
57. Desiere E., McShan W.M., van Sinderen D., Ferretti J.J., and Brussow H. Comparative genomics reveals close genetic relationships between phages from dairy bacteria and pathogenic streptococci: evolutionary implications for prophage-host interactions. Virology 288 (2001) 325-341
58. Desiere E., Lucchini S., Canchaya C., Ventura M., and Brussow H. Comparative genomics of phages and prophages in lactic acid bacteria. Antonie van Leeuwenhoek 82 (2002) 73-91
59. Dinsmore P.K., and Klaenhammer T.R. Bacteriophage resistance in Lactococcus. Mol. Biotechnol. 4 (1995) 297-314
60. Dinsmore P.K., and Klaenhammer T.R. Molecular characterization of a genomic region in a Lactococcus bacteriophage that is involved in its sensitivity to the phage defense mechanism AbiA. J. Bacteriol. 179 (1997) 2949-2957
61. Djordjevic G.M., and Klaenhammer T.R. Bacteriophagetriggered defence systems: phage adaptation and design improvements. Appl. Environ. Microbiol. 63 (1997) 4370-4376
62. Djordjevic G.M., O'Sullivan D.J., Walker S.A., Conkling M.A., and Klaenhammer T.R. A triggered-suicide system designed as a defence against bacteriophage. J. Bacteriol 179 (1997) 6741-6748
63. Dreiseikelmann B. Translocation of DNA across bacterial membranes. Microbiol. Rev. 58 (1994) 293-316
64. Durmaz E., and Klaenhammer T.R. Genetic analysis of chromosomal regions of Lactococcus lactis acquired by recombinant lytic phages. Appl. Environ. Microbiol. 66 (2000) 895-903
65. Durmaz E., Higgins D.L., and Klaenhammer T.R. Molecular characterization of a second abortive phage resistance gene present in Lactococcus lactis subsp. lactis ME2. J. Bacteriol. 174 (1992) 7463-7469
66. Ecker J.R., and Davis R.W. Inhibition of gene expression in plant cells by expression of antisense RNA. Proc. Natl Acad. Sci. USA 83 (1986) 5372-5376
67. Emond E., Holler B.J., Boucher I., Vandenbergh P.A., Vedamuthu E.R., Kondo J.K., and Moineau S. Phenotypic and genetic characterization of the bacteriophage abortive infection mechanism AbiK from Lactococcus lactis. Appl Environ. Microbiol. 63 (1997) 1274-1283
68. Emond E., Dion E., Walker S.A., Vedamuthu E.R., Kondo J.K., and Moineau S. AbiQ, an abortive infection mechanism from Lactococcus lactis. Appl. Environ. Microbiol. 64 (1998) 4748-4756
69. Fayard B., Haeflinger M., and Accolas J.R. Interaction of temperate bacteriophages of Streptococcus salivarius subsp. thermophilus with lysogenic indicators affect phage DNA restriction patterns and host ranges. J. Dairy Sci. 60 (1993) 385-399
70. Foley S., Lucchini S., Zwahlen M.-C., Sidoti J., and Brüssow H. A short non-coding viral DNA element showing characteristics of a replication origin confers bacteriophage resistance to Streptococcus thermophilus. Virology 250 (1998) 377-387
71. Forde A., and Fitzgerald G.F. Bacteriophage defence systems in lactic acid bacteria. In: Konings W.N., Kuipers O.P., and Huisin'tveld J.H.J. (Eds). Proceedings of the Sixth Symposium on Lactic acid bacteria (1999), Kluwer Academic Publishers, London
72. 2 . Appl. Environ. Microbiol. 65 (1999) 1540-1547
73. Forsman P. Characterization of a prolate-headed bacteriophage of Lactobacillus delbrueckii subsp. lactis and its DNA homology with isometric-headed phages. Arch. Virol. 132 (1993) 321-330
74. Forsman P., and Alatossava T. Genetic variation of Lactobacillus delbrueckii subsp. lactis bacteriophage isolated from cheese processing plants in Finland. Appl. Environ. Microbiol. 57 (1991) 1805-1812
75. Garbutt K.C., Kraus J., and Geller B.L. Bacteriophage resistance in Lactococcus lactis engineered by replacement of a gene for a bacteriophage receptor. J. Dairy Sci. 80 (1997) 1512-1519
76. Garcia P., Garcia J.L., Garcia E., Sánchez-Puelles J.M., and López R. Modular organisation of the lytic enzymes of Streptococcus pneumoniae and its bacteriophages. Gene 86 (1990) 81-88
77. Garcia P., Alonso J.C., and Suárez J.E. Molecular analysis of the cos region of the Lactobacillus casei bacteriophage A2. Gene product 3, gp3 specifically binds to its downstream cos region. Mol. Microbiol. 23 (1997) 505-514
78. Garcia P., Ladero V., Alonso J.C., and Suárez J.E. Cooperative interaction of CI protein regulates lysogeny of Lactobacillus casei by bacteriophage A2. J. Virol. 73 (1999) 3920-3929
79. Garvey P., van Sinderen D., Twomey D.P., Hill C., and Fitzgerald G.F. Molecular genetics of bacteriophage and natural phage defence systems in the genus Lactococcus. Int. Dairy J. 5 (1995) 905-947
80. Garvey P., Fitzgerald G.F., and Hill C. Cloning and DNA sequence analysis of two abortive infection phage resistance determinants from the lactococcal plasmid pNP40. Appl. Environ. Microbiol. 61 (1995) 4321-4328
81. Garvey P., Hill C., and Fitzgerald G.F. The lactococcal plasmid pNP40 encodes a third bacteriophage resistance mechanism, one which affects phage DNA penetration. Appl. Environ. Microbiol. 62 (1996) 676-679
82. Garvey P., Rince A., Hill C., and Fitzgerald G.F. Identification of a recA homolog (recALP) on the conjugative lactococcal phage resistance plasmid pNP40: evidence of a role for chromosomally encoded recAL in abortive infection. Appl Environ. Microbiol. 63 (1997) 1244-1251
83. Geller B.L., Ivey R.G., Trempy J.E., and Hettinger-Smith B. Cloning of a chromosomal gene required for phage infection of Lactococcus lactis subsp. lactis C2. J. Bacteriol 175 (1993) 5510-5519
84. Heap H.A., and Lawrence R.C. The selection of starter strains for cheese making. NZJ. Dairy Sci. Technol. 11 (1976) 16-20
85. Hendrix R.W., Smith M.C.M., Burns R.N., Ford M.E., and Hatful G.F. Evolutionary relationships among diverse bacteriophages and prophages: all the world's a phage. Proc. Natl. Acad. Sci. USA 96 (1999) 2192-2197
86. Herrero M., de los Reyes Gavilan C.G., Caso J.L., and Suarez J.E. Characterisation of phi 393-A2 bacteriophage that infects Lactobacillus casei. Microbiology 140 (1994) 2585-2590
87. Hill C. Bacteriophage and bacteriophage resistance in lactic acid bacteria. FEMS Microbiol. Rev. 12 (1993) 87-108
88. Hill C., Pierce K., and Klaenhammer T.R. The conjugative plasmid pTR2030 encodes two bacteriophage defense mechanisms in lactococci, restriction modification (R+/M + ) and abortive infection (Hsp + ). Appl. Environ. Microbiol. 55 (1989) 2416-2419
89. Hill C., Miller L.A., and Klaenhammer T.R. Cloning, expression, and sequence determination of a bacteriophage fragment encoding bacteriophage resistance in Lactococcus lactis. J. Bacteriol 172 (1990) 6419-6426
90. Hill C., Miller L.A., and Klaenhammer T.R. Nucleotide sequence and distribution of the pTR2030 resistance determinant (hsp) which aborts bacteriophage infection in lactococci. Appl. Environ. Microbiol. 56 (1990) 2255-2258
91. Hill C., Miller L.A., and Klaenhammer T.R. In vitro genetic exchange of a functional domain from a type II A methylase between lactococcal plasmid pTR2030 and a virulent bacteriophage. J. Bacteriol 173 (1991) 4363-4370
92. Huggins A.R., and Sandine W.E. Incidence and properties of temperate bacteriophages induced from lactic streptococci. Appl. Environ. Microbiol. 33 (1977) 184-191
93. Inouye M. Antisense RNA: its functions and applications in gene regulation - a review. Gene 72 (1988) 25-34
94. Izant J.G., and Weintraub H. Inhibition of thymidine kinase gene expression by anti-sense RNA: a molecular approach to genetic analysis. Cell 36 (1984) 1007-1015
95. Jarvis A.W. Bacteriophages of lactic acid bacteria. J. Dairy Sci. 72 (1989) 3406-3428
96. Jarvis A.W., Fitzgerald G.F., Mata M., Mercenier A., Neve H., Powell I.B., Ronda C., Saxelin M., and Teuber M. Species and type phages of lactococcal bacteriophages. Intervirology 32 (1991) 2-9
97. Jarvis A.W., Lubbers M.W., Beresford T.P., Ward L.J., Waterfield N.R., Collins L.J., and Jarvis B.D. Molecular biology of lactococcal bacteriophage c2. Dev. Biol. Stand. 85 (1995) 561-567
98. Johnsen M.G., Appel K.F., Madsen P.L., Vogensen F.K., Hammer K., and Arnau J. A genomic region of the lactococcal temperate bacteriophage TP901-1 encoding major virion proteins. Virology 218 (1996) 306-315
99. Kakikawa M., Ohkubo S., Syama M., Taketo A., and Kodaira K.I. The genetic switch for the regulatory pathway of Lactobacillus plantarum phage gle: characterization of the promoter P(L), the repressor gene cpg, and the cpg-encoded protein Cpg in Escherichia coli. Gene 242 (2000) 155-166
100. Keogh B.P., and Pettinghill G. Adsorption of bacteriophage eb7 on Streptococcus cremoris EB7. Appl. Environ. Microbiol. 45 (1983) 1946-1948
101. Kim S.G., and Batt C.A. Identification of a nucleotide sequence conserved in Lactococcus lactis bacteriophages. Gene 98 (1991) 95-100
102. Kim S.G., and Batt C.A. Antisense mRNA-mediated bacteriophage resistance in Lactococcus lactis. Appl. Environ. Microbiol. 57 (1991) 1109-1113
103. Kim S.G., Bor Y.-C., and Batt C.A. Bacteriophage resistance in Lactococcus lactis spp. lactis using antisense ribonucleic acid. J. Dairy Sci. 75 (1992) 1761-1767
104. Kim J.H., Kim S.G., Chung D.K., Bor Y.C., and Batt C.A. Use of antisense RNA to confer bacteriophage resistance in dairy starter cultures. J. Ind. Microbiol. 10 (1992) 71-78
105. Kivi S., Peltomaki T., Luomala K., and Sarimo S.S. Some properties of Streptococcus ihermophilus bacterio- phages. Folia. Microbiol. 32 (1987) 101-106
106. Klaenhammer T.R., and Fitzgerald G.F. Bacteriophages and bacteriophage resistance. In: Gasson M.J., and de Vos W. (Eds). Genetics and Biotechnology of Lactic Acid Bacteria (1994), Blackie Academic and Professional, Veldhoven, The Netherlands 106-168
107. Kodaira K.-I., Oki M., Kakikawa M., Watanabe N., Hirakawa M., Yamada K., and Taketo A. Genome structure of the Lactobacillus temperate phage gle: the whole genome sequence and the putative promoter repressor system. Gene 187 (1997) 45-53
108. Kraus J., and Geller B.L. Membrane receptor for prolate phages is not required for infection of Lactococcus lactis by small or large isometric phages. J. Dairy Sci. 81 (1998) 2329-2335
109. Labrie S., and Moineau S. Complete genomic sequence of bacteriophage ul36: demonstration of phage heterogeneity within the P335 quasi-species of lactococ- cal phages. Virology 296 (2002) 308-320
110. Ladero V., Garcia P., Bascarán V., Herrero M., Álvarez M.A., and Suárez J.E. Identification of the repressorencoding gene of the Lactobacillus bacteriophage A2. J. Bacteriol. 180 (1998) 3474-3476
111. Ladero V., Garcia P., Alonso J.C., and Suarez J.E. A2 cro, the lysogenic cycle repressor, specifically binds to the genetic switch region of Lactobacillus casei bacteriophage A2. Virology 262 (1999) 220-229
112. Lahbib-Mansais Y., Mata M., and Ritzenthaler P. Molecular taxonomy of Lactobacillus phages. Biochimie 70 (1988) 429-435
113. Larbi D., Decaris B., and Simonet J.M. Different bacteriophage resistance mechanisms in Streptococcus salivarius subsp. thermophilus. J. Dairy Res. 59 (1992) 349-357
114. Le Marrec C., van Sinderen D., Walsh L., Stanley E., Vlegels E., Moineau S., Heinze P., Fitzgerald G., and Fayard B. Streptococcus thermophilus bacteriophages can be divided into two distinct groups based on mode of packaging and structural protein composition. Appl. Environ. Microbiol. 63 (1997) 3246-3253
115. Lillehaug D., and Birkeland N.-K. Characterization of genetic elements required for site-specific integration of the temperate lactococcal bacteriophage LC3 and construction of integration-negative LC3 mutants. J. Bacteriol. 175 (1993) 1745-1755
116. Limsowtin G.K.Y., Powell I.B., and Parente E. Types of starters. In: Cogan T.M., and Accolas J.P. (Eds). Dairy Starter Cultures (1996), VCH, Glasgow 101-129
117. Little J.W. LexA cleavage and other self-processing reactions. J. Bacteriol. 175 (1993) 4943-4950
118. Lubbers M.W., Waterfield N.R., Beresford T.R., Le Page R.W.J., and Jarvis A.J. Sequencing and analysis of the prolate-headed lactococcal bacteriophage c2 genome and identification of the structural genes. Appl. Environ. Microbiol. 61 (1995) 4348-4356
119. Lucchini S., Desiere F., and Brüssow H. The structural gene module in Streptococcus thermophilus bacteriophage Sfi 11 shows a hierarchy of relatedness to Siphoviridae from a wide range of bacterial hosts. Virology 246 (1998) 63-73
120. Lucchini S., Desiere F., and Brüssow H. The genetic relationship between virulent and temperate Streptococcus thermophilus bacteriophages: whole genome comparison of cos-site phages øSfil9 and øSfi21. Virology 260 (1999) 232-243
121. Lucchini S., Desiere F., and Brüssow H. Similarly organized lysogeny modules in temperate Siphoviridae from low GC content Gram-positive bacteria. Virology 263 (1999) 427-435
122. Lucchini S., Sidoti J., and Brussow H. Broad-range bacteriophage resistance in Streptococcus thermophilus by insertional mutagenesis. Virology 275 (2000) 267-277
123. Madsen P.L., and Hammer K. Temporal transcription of the lactococcal temperate phage TP901-1 and DNA sequence of the early promoter region. Microbiology 144 (1998) 2203-2215
124. Madsen A., and Josephsen J. Characterization of LlaCI, a new restriction-modification system from Lactococcus lactis subsp. cremoris W15. J. Biol. Chem. 379 (1998) 443-449
125. Madsen A., and Josephsen J. Cloning and characterization of the lactococcal plasmid-encoded type II restriction/modification system, LlaDII. Appl. Environ. Microbiol. 64 (1998) 2424-2431
126. Madsen P.L., Johansen A.H., Hammer K., and Brøndsted L. The genetic switch regulating activity of early promoters of the temperate lactococcal bacteriophage TP901-1. J. Bacteriol. 181 (1999) 7430-7438
127. Madsen S.M., Mills D., Djordjevic G., Israelsen H., and Klaenhammer T.R. Analysis of the genetic switch and replication region of a P335-type bacteriophage with an obligate lytic lifestyle on Lactococcus lactis. Appl. Environ. Microbiol. 67 (2001) 1128-1139
128. Mahanivong C., Boyce J.D., Davidson B.E., and Hillier A.J. Sequence analysis and molecular characterization of the Lactococcus lactis temperate bacteriophage BK5-T. Appl Environ. Microbiol. 67 (2001) 3564-3576
129. Marians K.J. Prokaryotic DNA replication. Ann. Rev. Biochem. 61 (1992) 673-719
130. Marshall R.J., and Berridge N.J. Selection and some properties of phage-resistant starters for cheese-making. J. Dairy Res. 43 (1976) 449-458
131. Mata M., and Ritzenthaler P. Present state of lactic acid bacteria phage taxonomy. Biochimie 70 (1988) 395-399
132. Mata M., Trautwetter A., Luthaud G., and Ritzenthaler P. Thirteen virulent and temperate bacteriophages of Lactobacillus bulgaricus and Lactobacillus lactis belong to a single DNA homology group. Appl. Environ. Microbiol. 52 (1986) 812-818
133. Matz K., Schmandt M., and Gussin G.N. The rex gene of bacteriophage lambda is really two genes. Genetics 102 (1982) 319-327
134. McGrath S., Seegers J.F.M., Fitzgerald G.F., and van Sinderen D. Molecular characterisation of a phage-encoded resistance system in Lactococcus lactis. Appl. Environ. Microbiol. 65 (1999) 1891-1899
135. McGrath S., Fitzgerald G.F., and van Sinderen D. Improvement and optimization of two engineered phage resistance mechanisms in Lactococcus lactis. Appl. Environ. Microbiol. 67 (2001) 608-616
136. McGrath S., Fitzgerald G.F., and van Sinderen D. Identification and characterization of phage-resistance genes in temperate lactococcal bacteriophages. Mol. Microbiol. 43 (2002) 509-520
137. McGrath S., van Sinderen D., and Fitzgerald G.F. Bacteriophage-derived genetic tools for use in lactic acid bacteria. Int. Dairy J. 12 (2002) 3-15
138. McLandsborough L.A., Kolaetis K.M., Requena T., and McKay L.L. Cloning and characterization of the abortive infection genetic determinant abiD isolated from pBF61 of Lactococcus lactis subsp. lactis KR5. Appl. Environ. Microbiol. 61 (1995) 2023-2026
139. Mikkonen M., Räisänen L., and Alatossava T. The early region completes the nucleotide sequence of Lactobacillus delbrueckii subsp. lactis phage LL-H. Gene 175 (1996) 49-57
140. Moineau S. Applications of phage resistance in lactic acid bacteria. Antonie van Leeuwenhoek 76 (1999) 377-382
141. Moineau S., Fortier J., Ackermann H.W., and Pandian S. Characterization of lactococcal bacteriophages from Quebec cheese plants. Can. J. Microbiol 38 (1992) 875-882
142. Moineau S., Pandian S., and Klaenhammer T.R. Evolution of a lytic bacteriophage via DNA acquisition from the Lactococcus lactis chromosome. Appl. Environ. Microbiol. 60 (1994) 1832-1841
143. Moineau S., Walker S.A., Vedamuthu E.R., and Vandenbergh P.A. Cloning and sequencing of LlaDCHI restriction/modification genes from Lactococcus lactis and relatedness of this system to the Streptococcus pneumoniae DpnII system. Appl. Environ. Microbiol 61 (1995) 2193-2202
144. Moineau S., Borkaev M., Holler B.J., Walker S.J., Kondo J.K., Vedamuthu E.R., and Vandenbergh P.A. Isolation and characterization of lactococcal bacteriophages from cultured buttermilk plants in the United States. J. Dairy Sci. 79 (1996) 2104-2111
145. Monteville M.R., Ardestani B., and Geller B.L. Lactococcal bacteriophages require a host cell wall carbohydrate and a plasma membrane protein for adsorption and ejection of DNA. Appl. Environ. Microbiol. 60 (1994) 3204-3211
146. Moscoso M., and Suarez J.E. Characterization of the DNA replication module of bacteriophage A2 and use of its origin of replication as a defense against infection during milk fermentation by Lactobacillus casei. Virology 273 (2000) 101-111
147. Murialdo H. Bacteriophage lambda DNA maturaion and packaging. Biochemistry 60 (1991) 125-153
148. Nakashima Y., Ikeda H., Kakita Y., Miake F., and Watanabe K. Restriction map of the genomic DNA of Lactobacillus casei bacteriophage PL-1 and nucleotide sequence of its cohesive single-stranded ends. J. Gen. Virol. 75 (1994) 2537-2541
149. Nauta A., van Sinderen D., Karsens H., Smit E., Venema G., and Kok J. Inducible gene expression mediated by a repressor-operator system isolated from Lactococcus lactis bacteriophage rlt. Mol. Microbiol. 19 (1996) 1331-1341
150. Nauta A., van de Burg B., Karsens H., Venema G., and Kok J. Design of thermolabile bacteriophage repressor mutants by comparative molecular modeling. Nature Biotechnol. 15 (1997) 980-983
151. Neve H. Bacteriophage. In: Cogan T.M., and Accolas J.P. (Eds). Dairy Starter Cultures (1996), VCH Publishers, New York 157-189
152. Neve H., Krusch U., and Teuber M. Classification of virulent bacteriophages of Streptococcus salivarius subsp. thermophilus isolated from yoghurt and Swiss-type cheese. Appl Microbiol Biotechnol 30 (1989) 624-629
153. Neve H., Zenz K.I., Desiere F., Koch A., Heller K.J., and Brussow H. Comparison of the lysogeny modules from the temperate Streptococcus thermophilus bacterio- phages TP-J34 and øSfi21: implications for the modular theory of phage evolution. Virology 241 (1998) 61-72
154. Nyengaard N.R., Falkenberg-Klok J., and Josephsen J. Cloning and analysis of the restriction-modification system LlaBI, a bacteriophage resistance system from Lactococcus lactis subsp. cremoris W56. Appl. Environ. Microbiol. 62 (1996) 3494-3498
155. O'Connor L., Coffey A., Daly C., and Fitzgerald G.F. AbiG, a genotypically novel abortive infection mechanism encoded by plasmid pCI750 of Lactococcus lactis subsp. cremoris UC653. Appl. Environ. Microbiol. 62 (1996) 3075-3082
156. Oram J. Isolation and properties of a phage receptor substance from the plasma membrane of Streptococcus lactis ML3. J. Gen. Virol. 13. (1971) 59-71
157. O'Sullivan D.J., Hill C., and Klaenhammer T.R. Effect of increasing the copy number of bacteriophage origins of replication, in trans, on incoming-phage proliferation. Appl Environ. Microbiol. 59 (1993) 2449-2456
158. O'Sullivan D.J., Zagula K., and Klaenhammer T.R. In vivo restriction by Llal is encoded by three genes, arranged in an operon with llalM, on the conjugative Lactococcus plasmid pTR2030. J. Bacteriol. 177 (1995) 134-143
159. O'Sullivan T., van Sinderen D., and Fitzgerald G. Structural and functional analysis of pCI65st, a 6.5 kb plasmid from Streptococcus thermophilus NDI-6. Microbiology 145 (1999) 127-134
160. O'Sullivan D., Twomey D.P., Coffey A., Hill C., Fitzgerald G.E., and Ross R.P. Novel type I restriction specificities through domain shuffling of HsdS subunits in Lactococcus lactis. Mol. Microbiol. 36 (2000) 866-875
161. O'Sullivan D., Ross R.P., Twomey D.P., Fitzgerald G.E., Hill C., and Coffey A. Naturally occurring lactococcal plasmid pAH90 links bacteriophage resistance and mobility functions to a food-grade selectable marker. Appl. Environ. Microbiol 67 (2001) 929-937
162. Parreira R., Valyasevi R., Lerayer A.L.S., Ehrlich D.S., and Chopin M.C. Gene organization and transcription of a late-expressed region of a Lactococcus lactis phage. J. Bacteriol 178 (1996) 6158-6165
163. Prevots F., and Ritzenthaler P. Complete sequence of the new lactococcal abortive phage resistance gene abiO. J. Dairy Sci. 81 (1998) 1483-1485
164. Prévots F., Relano P., Mata M., and Ritzenthaler P. Close relationship of virulent bacteriophages of Streptococcus salivarius subsp. thermophilus at both the protein and the DNA level. J. Gen. Microbiol 135 (1989) 3337-3344
165. Prévots F., Mata M., and Ritzenthaler P. Taxonomic differentiation of 101 lactococcal bacteriophages and characterization of bacteriophages with unusually large genomes. Appl. Environ. Microbiol. 56 (1990) 2180-2185
166. Préevots F., Daloyau M., Bonin O., Dumont X., and Tolou S. Cloning and sequencing of the novel abortive infection gene abiH of Lactococcus lactis ssp. lactis biovar. diacetylactis S94. FEMS Microbiol. Lett. 142 (1996) 295-299
167. Prévots E., Tolou S., Delpech B., Kaghad M., and Daloyau M. Nucleotide sequence and analysis of the new chromosomal abortive infection gene abiN of Lactococcus lactis subsp. cremoris S1 14. FEMS Microbiol. Lett. 159 (1998) 331-336
168. Proux C., van Sinderen D., Suarez J., García P., Ladero V., Fitzgerald G.F., Desiere F., and Brussow H. The dilemma of phage taxonomy illustrated by comparative genomics of sfi21-like Siphoviridae in lactic acid bacteria. J. Bacteriol. 184 (2002) 6026-6036
169. Ptashne M. A Genetic Switch: Gene Control and Phage Lambda (1986), Blackwell Scientific Publications, New York
170. Raya R.R., and Klaenhammer T.R. High-frequency plasmid transduction by Lactobacillus gasseri bacterio-phage phi adh. Appl. Environ. Microbiol. 58 (1992) 187-193
171. Raya R.R., Fremaux C., de Antoni G.L., and Klaenhammer T.R. Site-specific integration of the temperate bacte-riophage adh into the Lactobacillus gasseri chromosome and molecular characterization of the phage (attP)and bacterial (attB) attachment sites. J. Bacteriol. 174 (1992) 5584-5592
172. Reiter B. Lysogenic strains of lactic streptococci. Nature 164 (1949) 667-668
173. Reiter B. Inhibition of lactic Streptococcus bacteriophage. Dairy Industries 21 (1956) 877-879
174. Relano P., Mata M., Bonneau M., and Ritzenthaler P. Molecular characterisation and comparison of 38 virulent and temperate bacteriophages of Streptococcus lactis. J. Gen. Microbiol. 133 (1987) 3053-3063
175. Rodgers H.J., Perkins H.R., and Ward J.B. Microbial Cell Walls and Membranes (1980), Chapman & Hall, Palo Alto, CA
176. Saxelin M.L., Nurmiaho E.L., Korhola M.P., and Sundman V. Partial characterization of a new C3-type capsule-dissolving phage of Streptococcus cremoris. Can. J. Microbiol. 25 (1979) 1182-1187
177. Saxelin M.L., Nurmiaho E.L., Merilainen V.T., and Forsen R.I. Ultrastructure and host specificity of bacterio phages of Streptococcus cremoris, Streptococcus lactis subsp. diacetylactis, and Leuconostoc cremoris from Finnish fermented milk "Viili". Appl. Environ. Microbiol. 52 (1986) 771-777
178. Schafer A., Geis A., Neve H., and Teuber M. Bacteriophage receptors of Lactococcus lactis subsp. 'diacetylactis' F7/2 and Lactococcus lactis subsp. cremoris Wg2-1. FEMS Microbiol. Lett. 62 (1991) 69-73
179. Schouler C., Ehrlich S.D., and Chopin M.C. Sequence and organization of the lactococcal prolate-headed bIL67 phage genome. Microbiology 140 (1994) 3061-3069
180. Schouler C., Clier F., Lerayer A.L., Ehrlich S.D., and Chopin M.C. A type IC restriction-modification system in Lactococcus lactis. J. Bacteriol. 180 (1998) 407-411
181. Schouler C., Gautier M., Ehrlich S.D., and Chopin M.C. Combinational variation of restriction modification specificities in Lactococcus lactis. Mol. Microbiol. 28 (1998) 169-178
182. Schuch R., Nelson D., and Fischetti V.A. A bacteriolytic agent that detects and kills Bacillus anthracis. Nature 418 (2002) 884-889
183. Sechaud L., Cluzel P.-J., Rousseau M., Baumgartner A., and Accolas J.P. Bacteriophages of lactobacilli. Biochimie 70 (1988) 401-410
184. Sechaud L., Rousseau M., Fayard B., Callegari M.L., Quénée P., and Accolas J.P. Comparative study of 35 bacteriophages of Lactobacillus helveticus: morphology and host range. Appl. Environ. Microbiol. 58 (1992) 1011-1018
185. Seegers J.E., van Sinderen D., and Fitzgerald G.F. Molecular characterization of the lactococcal plasmid pCIS3: natural stacking of specificity subunits of a type I restriction/modification system in a single lactococcal strain. Microbiology 146 (2000) 435-443
186. Shearman C., Jury K., and Gasson M.J. Controlled expression and structural organisation of a Lactococcus lactis bacteriophage lysin encoded by two overlapping genes. Appl. Environ. Microbiol. 60 (1994) 3063-3073
187. Sheehan M., García J.L., López R., and García P. Analysis of the catalytic domain of the lysin of the lactococcal bacteriophage Tuc2009 by chimeric gene assembling. FEMS Microbiol Lett. 140 (1996) 23-28
188. Sheehan M.M., Stanley E., Fitzgerald G.E., and van Sinderen D. Identification and characterisation of a lysis module present in a large proportion of bacteriophages infecting Stretococcus thermophilus. Appl Environ. Microbiol 65 (1999) 569-577
189. Solow B.T., and Somkuti G.A. Molecular properties of Streptococcus thermophilus plasmid pER35 encoding a restriction modification system. Curr. Microbiol 42 (2001) 122-128
190. Stanley G. Cheeses. In: Wood J.B. (Ed). Microbiology of Fermented Foods (1998), Blackie Academic and Professional, London 263-307
191. Stanley E., Fitzgerald G.E., Le Marrec C., Fayard B., and van Sinderen D. Sequence analysis and characterisation of O1205, a temperate bacteriophage infecting Streptococcus thermophilus CNRZ1205. Microbiology 143 (1997) 3417-3429
192. Stanley E., Walsh L., van der Zwet A., Fitzgerald G.F., and van Sinderen D. Identification of four loci isolated from two Streptococcus thermophilus phage genomes responsible for mediating bacteriophage resistance. FEMS Microbiol. Lett. 182 (2000) 271-277
193. Stoll S.M., Ginsburg D.S., and Calos M.P. Phage TP901-1 site-specific integrase functions in human cells. J. Bacteriol. 184 (2002) 3657-3663
194. Stone R. Bacteriophage therapy. Stalin's forgotten cure. Science 298 (2002) 728-731
195. Streisinger G., Emrich J., and Stahl M.M. Chromosome structure in phage T4. III. Terminal redundancy and length determination. Proc. Natl. Acad. Sci. USA 57 (1967) 292-295
196. Sturino J.M., and Klaenhammer T.R. Expression of antisense RNA targeted against Streptococcus thermophilus bacteriophages. Appl. Environ. Microbiol. 68 (2002) 588-596
197. Su P., Harvey M., Im H.J., and Dunn N.W. Isolation, cloning and characterisation of the abil gene from Lactococcus lactis subsp. lactis M138 encoding abortive phage infection. J. Biotechnol. 54 (1997) 95-104
198. Su P., Im H., Hsieh H., Kang A.S., and Dunn N.W. LlaFI, a type III restriction and modification system in Lactococcus lactis. Appl. Environ. Microbiol. 65 (1999) 686-693
199. Susskind M.M., and Botstein D. Molecular genetics of bacteriophage P22. Microbiol. Rev. 42 (1978) 385-413
200. Susskind M.M., Botstein D., and Wright A. Superinfection exclusion by P22 prophage in lysogens of Salmonella typhimurium. II. Genetic evidence for two exclusion systems. Virology 45 (1971) 638-652
201. Tangney M., and Fitzgerald G.F. AbiA, a lactococcal abortive infection mechanism functioning in Streptococcus thermophilus. Appl. Environ. Microbiol. 68 (2002) 6388-6391
202. Tremblay D.M., and Moineau S. Complete genomic sequence of the lytic bacteriophage DTI of Streptococcus thermophilus. Virology 255 (1999) 63-76
203. Twomey D.P., Gabillet N., Daly C., and Fitzgerald G.F. Molecular characterization of the restriction endonuclease gene (scrFIR) associated with the ScrFI restriction/modification system from Lactococcus lactis subsp. cremoris UC503. Microbiology 143 (1997) 2277-2286
204. Twomey D.P., McKay L.L., and O'Sullivan D.J. Molecular characterization of the Lactococcus lactis LlaKR2I restriction-modification system and effect of an IS982 element positioned between the restriction and modification genes. J. Bacteriol. 180 (1998) 5844-5854
205. Twomey D.P., De Urraza R.J., McKay L.L., and O'Sullivan D.J. Characterization of AbiR, a novel multicomponent abortive infection mechanism encoded by plasmid pKR223 of Lactococcus lactis subsp. lactis KR2. Appl. Environ. Microbiol. 66 (2000) 2647-2651
206. Twort E.W. An investigation on the nature of ultramicroscopic viruses. Lancet 2 (1915) 1241-1243
207. Tye B., Huberman J., and Botstein D. Non-random circular permutation of phage P22. J. Mol. Biol. 85 (1974) 501-527
208. Valyasevi R., Sandine W.E., and Geller B.L. The bacteriophage kh receptor of Lactococcus lactis subsp. cremoris KH is the rhamnose of the extracellular wall polysaccharide. Appl. Environ. Microbiol. 56 (1990) 1882-1889
209. Valyasevi R., Sandine W.E., and Geller B.L. A membrane protein is required for bacteriophage c2 infection of Lactococcus lactis subsp. lactis C2. J. Bacteriol. 173 (1991) 6095-6100
210. Valyasevi R., Sandine W.E., and Geller B.L. Lactococcus lactis ssp. lactis C2 bacteriophage skl receptor involving rhamnose and glucose moieties in the cell wall. J. Dairy Sci. 77 (1994) 1-6
211. Van de Guchte M., Daly C., Fitzgerald G.E., and Arendt E.K. Identification of the putative repressor-encoding gene cI of the temperate lactococcal bacteriophage Tuc2009. Gene 144 (1994) 93-95
212. Van de Guchte M., Daly C., Fitzgerald G.E., and Arendt E.K. Identification of int and attP on the genome of the lactococcal bacteriophage Tuc2009 and their use for site-specific plasmid integration in the chromosome of Tuc2009-resistant Lactococcus lactis MG1363. Appl. Environ. Microbiol. 60 (1994) 2324-2329
213. Van Sinderen D., Karsens H., Kok J., Terpstra P., Ruiters M.H., Venema G., and Nauta A. Sequence analysis and molecular characterization of the temperate lactococcal bacteriophage rlt. Mol. Microbiol. 19 (1996) 1343-1355
214. Vasala A., Dupont L., Baumann M., Ritzenthaler P., and Alatossava T. Molecular comparison of the structural proteins encoding gene clusters of two related Lactobacillus delbrueckii bacteriophages. J. Virol. 67 (1993) 3061-3068
215. Waldor M.K. Bacteriophage biology and bacterial virulence. Trends Microbiol. 6 (1998) 295-297
216. Walker S.A., and Klaenhammer T.R. An explosive antisense RNA strategy for inhibition of a lactococcal bacteriophage. Appl. Environ. Microbiol. 66 (2000) 310-319
217. Watanabe K., Hayashia M., Ishibashi K., and Nakashima Y. An N-acetylmuramidase induced by PL-1 phage infection of Lactobacillus casei. J. Gen. Microbiol. 130 (1984) 275-277
218. Waterfield N.R., Lubbers M.W., Polzin K.M., le Page R.W.E., and Jarvis A.W. An origin of DNA replication from Lactococcus lactis bacteriophage c2. Appl. Environ. Microbiol. 62 (1996) 1452-1453
219. Whitehead H.R., and Cox G.A. The occurrence of bacteriophages in starter cultures of lactic streptococci. NZJ. Sci. Technol. 16 (1935) 319-320
220. Wilson G.G., and Murray N.E. Restriction and modification systems. Ann. Rev. Genet. 25 (1991) 585-627
221. Young R., and Bläsi U. Holins: form and function in bacteriophage lysis. FEMS Microbiol. Rev. 17 (1995) 191-205
222. Yu Y.T., and Snyder L. Translation elongation factor Tu cleaved by a phage-exclusion system. Proc. Natl. Acad. Sci. USA 91 (1994) 802-806.