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Volumn 113, Issue 4, 2010, Pages 836-847

FoxP1 promotes midbrain identity in embryonic stem cell-derived dopamine neurons by regulating Pitx3

Author keywords

Forkhead box P1; Midbrain dopaminergic neurons; Paired like homeodomain transcription factor 3; Transcription

Indexed keywords

DOPAMINE; LUCIFERASE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR FOXP1; TRANSCRIPTION FACTOR PITX3; UNCLASSIFIED DRUG;

EID: 77950941894     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2010.06650.x     Document Type: Article
Times cited : (26)

References (82)
  • 2
    • 33750326248 scopus 로고    scopus 로고
    • Transcriptional control of midbrain dopaminergic neuron development
    • Ang S. L. (2006) Transcriptional control of midbrain dopaminergic neuron development. Development 133, 3499 3506.
    • (2006) Development , vol.133 , pp. 3499-3506
    • Ang, S.L.1
  • 3
    • 33646872978 scopus 로고    scopus 로고
    • Chromatin signatures of pluripotent cell lines
    • Azuara V., Perry P., Sauer S. et al. (2006) Chromatin signatures of pluripotent cell lines. Nat. Cell Biol. 8, 532 538.
    • (2006) Nat. Cell Biol. , vol.8 , pp. 532-538
    • Azuara, V.1    Perry, P.2    Sauer, S.3
  • 4
    • 33646070846 scopus 로고    scopus 로고
    • A bivalent chromatin structure marks key developmental genes in embryonic stem cells
    • Bernstein B. E., Mikkelsen T. S., Xie X. et al. (2006) A bivalent chromatin structure marks key developmental genes in embryonic stem cells. Cell 125, 315 326.
    • (2006) Cell , vol.125 , pp. 315-326
    • Bernstein, B.E.1    Mikkelsen, T.S.2    Xie, X.3
  • 6
    • 3242695252 scopus 로고    scopus 로고
    • Genes, proteins, and neurotoxins involved in Parkinson's disease
    • Bohlen und H. O., Schober A. Krieglstein K. (2004) Genes, proteins, and neurotoxins involved in Parkinson's disease. Prog. Neurobiol. 73, 151 177.
    • (2004) Prog. Neurobiol. , vol.73 , pp. 151-177
    • Bohlen Und, H.O.1    Schober, A.2    Krieglstein, K.3
  • 7
    • 33646882068 scopus 로고    scopus 로고
    • Polycomb complexes repress developmental regulators in murine embryonic stem cells
    • Boyer L. A., Plath K., Zeitlinger J. et al. (2006) Polycomb complexes repress developmental regulators in murine embryonic stem cells. Nature 441, 349 353.
    • (2006) Nature , vol.441 , pp. 349-353
    • Boyer, L.A.1    Plath, K.2    Zeitlinger, J.3
  • 8
    • 0021954503 scopus 로고
    • Monitoring of cell viability in suspensions of embryonic CNS tissue and its use as a criterion for intracerebral graft survival
    • Brundin P., Isacson O. Bjorklund A. (1985) Monitoring of cell viability in suspensions of embryonic CNS tissue and its use as a criterion for intracerebral graft survival. Brain Res. 331, 251 259.
    • (1985) Brain Res. , vol.331 , pp. 251-259
    • Brundin, P.1    Isacson, O.2    Bjorklund, A.3
  • 9
    • 0036387193 scopus 로고    scopus 로고
    • Forkhead transcription factors: Key players in development and metabolism
    • Carlsson P. Mahlapuu M. (2002) Forkhead transcription factors: key players in development and metabolism. Dev. Biol. 250, 1 23.
    • (2002) Dev. Biol. , vol.250 , pp. 1-23
    • Carlsson, P.1    Mahlapuu, M.2
  • 10
    • 0034005734 scopus 로고    scopus 로고
    • A response element for the homeodomain transcription factor Ptx3 in the tyrosine hydroxylase gene promoter
    • Cazorla P., Smidt M. P., O'Malley K. L. Burbach J. P. (2000) A response element for the homeodomain transcription factor Ptx3 in the tyrosine hydroxylase gene promoter. J. Neurochem. 74, 1829 1837.
    • (2000) J. Neurochem. , vol.74 , pp. 1829-1837
    • Cazorla, P.1    Smidt, M.P.2    O'Malley, K.L.3    Burbach, J.P.4
  • 11
    • 13444256259 scopus 로고    scopus 로고
    • The homeodomain transcription factor Pitx3 facilitates differentiation of mouse embryonic stem cells into AHD2-expressing dopaminergic neurons
    • Chung S., Hedlund E., Hwang M., Kim D. W., Shin B. S., Hwang D. Y., Jung K. U., Isacson O. Kim K. S. (2005) The homeodomain transcription factor Pitx3 facilitates differentiation of mouse embryonic stem cells into AHD2-expressing dopaminergic neurons. Mol. Cell. Neurosci. 28, 241 252.
    • (2005) Mol. Cell. Neurosci. , vol.28 , pp. 241-252
    • Chung, S.1    Hedlund, E.2    Hwang, M.3    Kim, D.W.4    Shin, B.S.5    Hwang, D.Y.6    Jung, K.U.7    Isacson, O.8    Kim, K.S.9
  • 12
    • 33747587820 scopus 로고    scopus 로고
    • Neural precursors derived from embryonic stem cells, but not those from fetal ventral mesencephalon, maintain the potential to differentiate into dopaminergic neurons after expansion in vitro
    • Chung S., Shin B. S., Hwang M., Lardaro T., Kang U. J., Isacson O. Kim K. S. (2006) Neural precursors derived from embryonic stem cells, but not those from fetal ventral mesencephalon, maintain the potential to differentiate into dopaminergic neurons after expansion in vitro. Stem Cells 24, 1583 1593.
    • (2006) Stem Cells , vol.24 , pp. 1583-1593
    • Chung, S.1    Shin, B.S.2    Hwang, M.3    Lardaro, T.4    Kang, U.J.5    Isacson, O.6    Kim, K.S.7
  • 14
    • 47749149893 scopus 로고    scopus 로고
    • Hox repertoires for motor neuron diversity and connectivity gated by a single accessory factor, FoxP1
    • Dasen J. S., De Camilli A., Wang B., Tucker P. W. Jessell T. M. (2008) Hox repertoires for motor neuron diversity and connectivity gated by a single accessory factor, FoxP1. Cell 134, 304 316.
    • (2008) Cell , vol.134 , pp. 304-316
    • Dasen, J.S.1    De Camilli, A.2    Wang, B.3    Tucker, P.W.4    Jessell, T.M.5
  • 15
    • 0040368216 scopus 로고    scopus 로고
    • Prospects for new restorative and neuroprotective treatments in Parkinson's disease
    • Dunnett S. B. Bjorklund A. (1999) Prospects for new restorative and neuroprotective treatments in Parkinson's disease. Nature 399, A32 A39.
    • (1999) Nature , vol.399
    • Dunnett, S.B.1    Bjorklund, A.2
  • 16
    • 0035347165 scopus 로고    scopus 로고
    • Cell therapy in Parkinson's disease -stop or go?
    • DOI 10.1038/35072572
    • Dunnett S. B., Bjorklund A. Lindvall O. (2001) Cell therapy in Parkinson's disease - stop or go? Nat. Rev. Neurosci. 2, 365 369. (Pubitemid 33680578)
    • (2001) Nature Reviews Neuroscience , vol.2 , Issue.5 , pp. 365-369
    • Dunnett, S.B.1    Bjorklund, A.2    Lindvall, O.3
  • 17
    • 0038727936 scopus 로고    scopus 로고
    • Description of Parkinson's disease as a clinical syndrome
    • Fahn S. (2003) Description of Parkinson's disease as a clinical syndrome. Ann. N Y Acad. Sci. 991, 1 14.
    • (2003) Ann. N y Acad. Sci. , vol.991 , pp. 1-14
    • Fahn, S.1
  • 18
    • 0025954066 scopus 로고
    • Ageing and Parkinson's disease: Substantia nigra regional selectivity
    • Fearnley J. M. Lees A. J. (1991) Ageing and Parkinson's disease: substantia nigra regional selectivity. Brain 114 (Pt 5 2283 2301.
    • (1991) Brain , vol.114 , Issue.PART 5 , pp. 2283-2301
    • Fearnley, J.M.1    Lees, A.J.2
  • 19
    • 34548186224 scopus 로고    scopus 로고
    • Foxa1 and Foxa2 regulate multiple phases of midbrain dopaminergic neuron development in a dosage-dependent manner
    • Ferri A. L., Lin W., Mavromatakis Y. E., Wang J. C., Sasaki H., Whitsett J. A. Ang S. L. (2007) Foxa1 and Foxa2 regulate multiple phases of midbrain dopaminergic neuron development in a dosage-dependent manner. Development 134, 2761 2769.
    • (2007) Development , vol.134 , pp. 2761-2769
    • Ferri, A.L.1    Lin, W.2    Mavromatakis, Y.E.3    Wang, J.C.4    Sasaki, H.5    Whitsett, J.A.6    Ang, S.L.7
  • 21
    • 0027979793 scopus 로고
    • Target and neurotransmitter specificity of fetal central nervous system transplants: Importance for functional reinnervation
    • Hudson J. L., Bickford P., Johansson M., Hoffer B. J. Stromberg I. (1994) Target and neurotransmitter specificity of fetal central nervous system transplants: importance for functional reinnervation. J. Neurosci. 14, 283 290.
    • (1994) J. Neurosci. , vol.14 , pp. 283-290
    • Hudson, J.L.1    Bickford, P.2    Johansson, M.3    Hoffer, B.J.4    Stromberg, I.5
  • 22
    • 0037786542 scopus 로고    scopus 로고
    • Selective loss of dopaminergic neurons in the substantia nigra of Pitx3-deficient aphakia mice
    • Hwang D. Y., Ardayfio P., Kang U. J., Semina E. V. Kim K. S. (2003) Selective loss of dopaminergic neurons in the substantia nigra of Pitx3-deficient aphakia mice. Brain Res. Mol. Brain Res. 114, 123 131.
    • (2003) Brain Res. Mol. Brain Res. , vol.114 , pp. 123-131
    • Hwang, D.Y.1    Ardayfio, P.2    Kang, U.J.3    Semina, E.V.4    Kim, K.S.5
  • 24
    • 33746640565 scopus 로고    scopus 로고
    • Stem cells primed for action: Polycomb repressive complexes restrain the expression of lineage-specific regulators in embryonic stem cells
    • Jorgensen H. F., Giadrossi S., Casanova M., Endoh M., Koseki H., Brockdorff N. Fisher A. G. (2006) Stem cells primed for action: polycomb repressive complexes restrain the expression of lineage-specific regulators in embryonic stem cells. Cell Cycle 5, 1411 1414.
    • (2006) Cell Cycle , vol.5 , pp. 1411-1414
    • Jorgensen, H.F.1    Giadrossi, S.2    Casanova, M.3    Endoh, M.4    Koseki, H.5    Brockdorff, N.6    Fisher, A.G.7
  • 25
    • 17344379513 scopus 로고    scopus 로고
    • Five years on the wings of fork head
    • Kaufmann E. Knochel W. (1996) Five years on the wings of fork head. Mech. Dev. 57, 3 20.
    • (1996) Mech. Dev. , vol.57 , pp. 3-20
    • Kaufmann, E.1    Knochel, W.2
  • 26
    • 0036582977 scopus 로고    scopus 로고
    • The neuroscience of natural rewards: Relevance to addictive drugs
    • Kelley A. E. Berridge K. C. (2002) The neuroscience of natural rewards: relevance to addictive drugs. J. Neurosci. 22, 3306 3311.
    • (2002) J. Neurosci. , vol.22 , pp. 3306-3311
    • Kelley, A.E.1    Berridge, K.C.2
  • 27
    • 12444281822 scopus 로고    scopus 로고
    • Dopaminergic neuronal differentiation from rat embryonic neural precursors by Nurr1 overexpression
    • Kim J. Y., Koh H. C., Lee J. Y. et al. (2003) Dopaminergic neuronal differentiation from rat embryonic neural precursors by Nurr1 overexpression. J. Neurochem. 85, 1443 1454.
    • (2003) J. Neurochem. , vol.85 , pp. 1443-1454
    • Kim, J.Y.1    Koh, H.C.2    Lee, J.Y.3
  • 28
    • 38549159511 scopus 로고    scopus 로고
    • The foxa2 gene controls the birth and spontaneous degeneration of dopamine neurons in old age
    • Kittappa R., Chang W. W., Awatramani R. B. McKay R. D. (2007) The foxa2 gene controls the birth and spontaneous degeneration of dopamine neurons in old age. PLoS Biol. 5, e325.
    • (2007) PLoS Biol. , vol.5 , pp. 325
    • Kittappa, R.1    Chang, W.W.2    Awatramani, R.B.3    McKay, R.D.4
  • 29
    • 5444269702 scopus 로고    scopus 로고
    • Parkinson's disease: Clinical aspects
    • Klockgether T. (2004) Parkinson's disease: clinical aspects. Cell Tissue Res. 318, 115 120.
    • (2004) Cell Tissue Res. , vol.318 , pp. 115-120
    • Klockgether, T.1
  • 30
    • 0032531924 scopus 로고    scopus 로고
    • Parkinson's disease. Second of two parts
    • Lang A. E. Lozano A. M. (1998) Parkinson's disease. Second of two parts. N. Engl. J. Med. 339, 1130 1143.
    • (1998) N. Engl. J. Med. , vol.339 , pp. 1130-1143
    • Lang, A.E.1    Lozano, A.M.2
  • 31
    • 0035051188 scopus 로고    scopus 로고
    • Pitx3 activates mouse tyrosine hydroxylase promoter via a high-affinity binding site
    • Lebel M., Gauthier Y., Moreau A. Drouin J. (2001) Pitx3 activates mouse tyrosine hydroxylase promoter via a high-affinity binding site. J. Neurochem. 77, 558 567.
    • (2001) J. Neurochem. , vol.77 , pp. 558-567
    • Lebel, M.1    Gauthier, Y.2    Moreau, A.3    Drouin, J.4
  • 32
    • 0034044317 scopus 로고    scopus 로고
    • Efficient generation of midbrain and hindbrain neurons from mouse embryonic stem cells
    • Lee S. H., Lumelsky N., Studer L., Auerbach J. M. McKay R. D. (2000) Efficient generation of midbrain and hindbrain neurons from mouse embryonic stem cells. Nat. Biotechnol. 18, 675 679.
    • (2000) Nat. Biotechnol. , vol.18 , pp. 675-679
    • Lee, S.H.1    Lumelsky, N.2    Studer, L.3    Auerbach, J.M.4    McKay, R.D.5
  • 33
    • 33646865180 scopus 로고    scopus 로고
    • Control of developmental regulators by Polycomb in human embryonic stem cells
    • Lee T. I., Jenner R. G., Boyer L. A. et al. (2006) Control of developmental regulators by Polycomb in human embryonic stem cells. Cell 125, 301 313.
    • (2006) Cell , vol.125 , pp. 301-313
    • Lee, T.I.1    Jenner, R.G.2    Boyer, L.A.3
  • 35
    • 0027133451 scopus 로고
    • DNA-binding properties and secondary structural model of the hepatocyte nuclear factor 3/fork head domain
    • Li C. Tucker P. W. (1993) DNA-binding properties and secondary structural model of the hepatocyte nuclear factor 3/fork head domain. Proc. Natl Acad. Sci. USA 90, 11583 11587.
    • (1993) Proc. Natl Acad. Sci. USA , vol.90 , pp. 11583-11587
    • Li, C.1    Tucker, P.W.2
  • 36
    • 69049108564 scopus 로고    scopus 로고
    • Foxa1 and Foxa2 function both upstream of and cooperatively with Lmx1a and Lmx1b in a feedforward loop promoting mesodiencephalic dopaminergic neuron development
    • Lin W., Metzakopian E., Mavromatakis Y. E. et al. (2009) Foxa1 and Foxa2 function both upstream of and cooperatively with Lmx1a and Lmx1b in a feedforward loop promoting mesodiencephalic dopaminergic neuron development. Dev. Biol. 333, 386 396.
    • (2009) Dev. Biol. , vol.333 , pp. 386-396
    • Lin, W.1    Metzakopian, E.2    Mavromatakis, Y.E.3
  • 37
    • 0034589755 scopus 로고    scopus 로고
    • Clinical observations after neural transplantation in Parkinson's disease
    • Lindvall O. Hagell P. (2000) Clinical observations after neural transplantation in Parkinson's disease. Prog. Brain Res. 127, 299 320.
    • (2000) Prog. Brain Res. , vol.127 , pp. 299-320
    • Lindvall, O.1    Hagell, P.2
  • 38
    • 67650604363 scopus 로고    scopus 로고
    • Generation of dopaminergic neurons from human fetal mesencephalic progenitors after co-culture with striatal-conditioned media and exposure to lowered oxygen
    • Liu S., Tian Z., Yin F., Zhao Q. Fan M. (2009) Generation of dopaminergic neurons from human fetal mesencephalic progenitors after co-culture with striatal-conditioned media and exposure to lowered oxygen. Brain Res. Bull. 80, 62 68.
    • (2009) Brain Res. Bull. , vol.80 , pp. 62-68
    • Liu, S.1    Tian, Z.2    Yin, F.3    Zhao, Q.4    Fan, M.5
  • 39
    • 20444376889 scopus 로고    scopus 로고
    • Pitx3 regulates tyrosine hydroxylase expression in the substantia nigra and identifies a subgroup of mesencephalic dopaminergic progenitor neurons during mouse development
    • Maxwell S. L., Ho H. Y., Kuehner E., Zhao S. Li M. (2005) Pitx3 regulates tyrosine hydroxylase expression in the substantia nigra and identifies a subgroup of mesencephalic dopaminergic progenitor neurons during mouse development. Dev. Biol. 282, 467 479.
    • (2005) Dev. Biol. , vol.282 , pp. 467-479
    • Maxwell, S.L.1    Ho, H.Y.2    Kuehner, E.3    Zhao, S.4    Li, M.5
  • 40
    • 33846470512 scopus 로고    scopus 로고
    • Induction of tyrosine hydroxylase expression by the transcription factor Pitx3
    • Messmer K., Remington M. P., Skidmore F. Fishman P. S. (2007) Induction of tyrosine hydroxylase expression by the transcription factor Pitx3. Int. J. Dev. Neurosci. 25, 29 37.
    • (2007) Int. J. Dev. Neurosci. , vol.25 , pp. 29-37
    • Messmer, K.1    Remington, M.P.2    Skidmore, F.3    Fishman, P.S.4
  • 41
    • 33750059753 scopus 로고    scopus 로고
    • Uracil nucleotides stimulate human neural precursor cell proliferation and dopaminergic differentiation: Involvement of MEK/ERK signalling
    • Milosevic J., Brandt A., Roemuss U., Arnold A., Wegner F., Schwarz S. C., Storch A., Zimmermann H. Schwarz J. (2006) Uracil nucleotides stimulate human neural precursor cell proliferation and dopaminergic differentiation: involvement of MEK/ERK signalling. J. Neurochem. 99, 913 923.
    • (2006) J. Neurochem. , vol.99 , pp. 913-923
    • Milosevic, J.1    Brandt, A.2    Roemuss, U.3    Arnold, A.4    Wegner, F.5    Schwarz, S.C.6    Storch, A.7    Zimmermann, H.8    Schwarz, J.9
  • 43
    • 55849117368 scopus 로고    scopus 로고
    • Generation of mouse induced pluripotent stem cells without viral vectors
    • Okita K., Nakagawa M., Hyenjong H., Ichisaka T. Yamanaka S. (2008) Generation of mouse induced pluripotent stem cells without viral vectors. Science 322, 949 953.
    • (2008) Science , vol.322 , pp. 949-953
    • Okita, K.1    Nakagawa, M.2    Hyenjong, H.3    Ichisaka, T.4    Yamanaka, S.5
  • 44
    • 0030041034 scopus 로고    scopus 로고
    • Fetal nigral transplantation as a therapy for Parkinson's disease
    • Olanow C. W., Kordower J. H. Freeman T. B. (1996) Fetal nigral transplantation as a therapy for Parkinson's disease. Trends Neurosci. 19, 102 109.
    • (1996) Trends Neurosci. , vol.19 , pp. 102-109
    • Olanow, C.W.1    Kordower, J.H.2    Freeman, T.B.3
  • 45
    • 0028353904 scopus 로고
    • The DNA-binding specificity of the hepatocyte nuclear factor 3/forkhead domain is influenced by amino-acid residues adjacent to the recognition helix
    • Overdier D. G., Porcella A. Costa R. H. (1994) The DNA-binding specificity of the hepatocyte nuclear factor 3/forkhead domain is influenced by amino-acid residues adjacent to the recognition helix. Mol. Cell. Biol. 14, 2755 2766.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 2755-2766
    • Overdier, D.G.1    Porcella, A.2    Costa, R.H.3
  • 46
    • 50249098740 scopus 로고    scopus 로고
    • Generation of human-induced pluripotent stem cells
    • Park I. H., Lerou P. H., Zhao R., Huo H. Daley G. Q. (2008) Generation of human-induced pluripotent stem cells. Nat. Protoc. 3, 1180 1186.
    • (2008) Nat. Protoc. , vol.3 , pp. 1180-1186
    • Park, I.H.1    Lerou, P.H.2    Zhao, R.3    Huo, H.4    Daley, G.Q.5
  • 47
    • 34548671917 scopus 로고    scopus 로고
    • Early specification of dopaminergic phenotype during ES cell differentiation
    • Parmar M. Li M. (2007) Early specification of dopaminergic phenotype during ES cell differentiation. BMC Dev. Biol. 7, 86.
    • (2007) BMC Dev. Biol. , vol.7 , pp. 86
    • Parmar, M.1    Li, M.2
  • 48
    • 0028046675 scopus 로고
    • Cloning and characterization of seven human forkhead proteins: Binding site specificity and DNA bending
    • Pierrou S., Hellqvist M., Samuelsson L., Enerback S. Carlsson P. (1994) Cloning and characterization of seven human forkhead proteins: binding site specificity and DNA bending. EMBO J. 13, 5002 5012.
    • (1994) EMBO J. , vol.13 , pp. 5002-5012
    • Pierrou, S.1    Hellqvist, M.2    Samuelsson, L.3    Enerback, S.4    Carlsson, P.5
  • 49
    • 30744461567 scopus 로고    scopus 로고
    • Development of dopaminergic neurons in the mammalian brain
    • Prakash N. Wurst W. (2006a) Development of dopaminergic neurons in the mammalian brain. Cell. Mol. Life Sci. 63, 187 206.
    • (2006) Cell. Mol. Life Sci. , vol.63 , pp. 187-206
    • Prakash, N.1    Wurst, W.2
  • 50
    • 33747670219 scopus 로고    scopus 로고
    • Genetic networks controlling the development of midbrain dopaminergic neurons
    • Prakash N. Wurst W. (2006b) Genetic networks controlling the development of midbrain dopaminergic neurons. J. Physiol. 575, 403 410.
    • (2006) J. Physiol. , vol.575 , pp. 403-410
    • Prakash, N.1    Wurst, W.2
  • 51
    • 0035850021 scopus 로고    scopus 로고
    • Transplantation of embryonic dopamine neurons for severe Parkinson's disease
    • Redmond D. E. Jr., Sladek J. R. Spencer D. D. (2001) Transplantation of embryonic dopamine neurons for severe Parkinson's disease. N. Engl. J. Med. 345, 146 147.
    • (2001) N. Engl. J. Med. , vol.345 , pp. 146-147
    • Redmond, Jr.D.E.1    Sladek, J.R.2    Spencer, D.D.3
  • 52
    • 47749129203 scopus 로고    scopus 로고
    • Coordinated actions of the forkhead protein Foxp1 and Hox proteins in the columnar organization of spinal motor neurons
    • Rousso D. L., Gaber Z. B., Wellik D., Morrisey E. E. Novitch B. G. (2008) Coordinated actions of the forkhead protein Foxp1 and Hox proteins in the columnar organization of spinal motor neurons. Neuron 59, 226 240.
    • (2008) Neuron , vol.59 , pp. 226-240
    • Rousso, D.L.1    Gaber, Z.B.2    Wellik, D.3    Morrisey, E.E.4    Novitch, B.G.5
  • 53
    • 0029004768 scopus 로고
    • Hepatocyte nuclear factor 3 determines the amplitude of the glucocorticoid response of the rat tyrosine aminotransferase gene
    • Roux J., Pictet R. Grange T. (1995) Hepatocyte nuclear factor 3 determines the amplitude of the glucocorticoid response of the rat tyrosine aminotransferase gene. DNA Cell Biol. 14, 385 396.
    • (1995) DNA Cell Biol. , vol.14 , pp. 385-396
    • Roux, J.1    Pictet, R.2    Grange, T.3
  • 54
    • 69249117837 scopus 로고    scopus 로고
    • Initiation of dopaminergic differentiation of Nurr1(-) mesencephalic precursor cells depends on activation of multiple mitogen-activated protein kinase pathways
    • Sabolek M., Baumann B., Heinrich M. et al. (2009) Initiation of dopaminergic differentiation of Nurr1(-) mesencephalic precursor cells depends on activation of multiple mitogen-activated protein kinase pathways. Stem Cells 27, 2009 2021.
    • (2009) Stem Cells , vol.27 , pp. 2009-2021
    • Sabolek, M.1    Baumann, B.2    Heinrich, M.3
  • 56
    • 0034234546 scopus 로고    scopus 로고
    • Deletion in the promoter region and altered expression of Pitx3 homeobox gene in aphakia mice
    • Semina E. V., Murray J. C., Reiter R., Hrstka R. F. Graw J. (2000) Deletion in the promoter region and altered expression of Pitx3 homeobox gene in aphakia mice. Hum. Mol. Genet. 9, 1575 1585.
    • (2000) Hum. Mol. Genet. , vol.9 , pp. 1575-1585
    • Semina, E.V.1    Murray, J.C.2    Reiter, R.3    Hrstka, R.F.4    Graw, J.5
  • 57
    • 0036955771 scopus 로고    scopus 로고
    • Selective prefrontal cortex inputs to dopamine cells: Implications for schizophrenia
    • Sesack S. R. Carr D. B. (2002) Selective prefrontal cortex inputs to dopamine cells: implications for schizophrenia. Physiol. Behav. 77, 513 517.
    • (2002) Physiol. Behav. , vol.77 , pp. 513-517
    • Sesack, S.R.1    Carr, D.B.2
  • 59
    • 58149386502 scopus 로고    scopus 로고
    • Down-regulation of the forkhead transcription factor Foxp1 is required for monocyte differentiation and macrophage function
    • Shi C., Sakuma M., Mooroka T. et al. (2008) Down-regulation of the forkhead transcription factor Foxp1 is required for monocyte differentiation and macrophage function. Blood 112, 4699 4711.
    • (2008) Blood , vol.112 , pp. 4699-4711
    • Shi, C.1    Sakuma, M.2    Mooroka, T.3
  • 60
    • 0035920153 scopus 로고    scopus 로고
    • Characterization of a new subfamily of winged-helix/forkhead (Fox) genes that are expressed in the lung and act as transcriptional repressors
    • Shu W., Yang H., Zhang L., Lu M. M. Morrisey E. E. (2001) Characterization of a new subfamily of winged-helix/forkhead (Fox) genes that are expressed in the lung and act as transcriptional repressors. J. Biol. Chem. 276, 27488 27497.
    • (2001) J. Biol. Chem. , vol.276 , pp. 27488-27497
    • Shu, W.1    Yang, H.2    Zhang, L.3    Lu, M.M.4    Morrisey, E.E.5
  • 61
    • 0038051417 scopus 로고    scopus 로고
    • Midbrain dopaminergic neurons: Determination of their developmental fate by transcription factors
    • Simon H. H., Bhatt L., Gherbassi D., Sgado P. Alberi L. (2003) Midbrain dopaminergic neurons: determination of their developmental fate by transcription factors. Ann. N Y Acad. Sci. 991, 36 47.
    • (2003) Ann. N y Acad. Sci. , vol.991 , pp. 36-47
    • Simon, H.H.1    Bhatt, L.2    Gherbassi, D.3    Sgado, P.4    Alberi, L.5
  • 62
    • 33845746199 scopus 로고    scopus 로고
    • How to make a mesodiencephalic dopaminergic neuron
    • Smidt M. P. Burbach J. P. (2007) How to make a mesodiencephalic dopaminergic neuron. Nat. Rev. Neurosci. 8, 21 32.
    • (2007) Nat. Rev. Neurosci. , vol.8 , pp. 21-32
    • Smidt, M.P.1    Burbach, J.P.2
  • 64
    • 0034034739 scopus 로고    scopus 로고
    • A second independent pathway for development of mesencephalic dopaminergic neurons requires Lmx1b
    • Smidt M. P., Asbreuk C. H., Cox J. J., Chen H., Johnson R. L. Burbach J. P. (2000) A second independent pathway for development of mesencephalic dopaminergic neurons requires Lmx1b. Nat. Neurosci. 3, 337 341.
    • (2000) Nat. Neurosci. , vol.3 , pp. 337-341
    • Smidt, M.P.1    Asbreuk, C.H.2    Cox, J.J.3    Chen, H.4    Johnson, R.L.5    Burbach, J.P.6
  • 66
    • 0242708712 scopus 로고    scopus 로고
    • Involvement of Nurr1 in specifying the neurotransmitter identity of ventral midbrain dopaminergic neurons
    • Smits S. M., Ponnio T., Conneely O. M., Burbach J. P. Smidt M. P. (2003) Involvement of Nurr1 in specifying the neurotransmitter identity of ventral midbrain dopaminergic neurons. Eur. J. Neurosci. 18, 1731 1738.
    • (2003) Eur. J. Neurosci. , vol.18 , pp. 1731-1738
    • Smits, S.M.1    Ponnio, T.2    Conneely, O.M.3    Burbach, J.P.4    Smidt, M.P.5
  • 67
    • 1642264043 scopus 로고    scopus 로고
    • Temporally induced Nurr1 can induce a non-neuronal dopaminergic cell type in embryonic stem cell differentiation
    • Sonntag K. C., Simantov R., Kim K. S. Isacson O. (2004) Temporally induced Nurr1 can induce a non-neuronal dopaminergic cell type in embryonic stem cell differentiation. Eur. J. Neurosci. 19, 1141 1152.
    • (2004) Eur. J. Neurosci. , vol.19 , pp. 1141-1152
    • Sonntag, K.C.1    Simantov, R.2    Kim, K.S.3    Isacson, O.4
  • 68
    • 0034871846 scopus 로고    scopus 로고
    • Long-term proliferation and dopaminergic differentiation of human mesencephalic neural precursor cells
    • Storch A., Paul G., Csete M., Boehm B. O., Carvey P. M., Kupsch A. Schwarz J. (2001) Long-term proliferation and dopaminergic differentiation of human mesencephalic neural precursor cells. Exp. Neurol. 170, 317 325.
    • (2001) Exp. Neurol. , vol.170 , pp. 317-325
    • Storch, A.1    Paul, G.2    Csete, M.3    Boehm, B.O.4    Carvey, P.M.5    Kupsch, A.6    Schwarz, J.7
  • 69
    • 0141673859 scopus 로고    scopus 로고
    • Functional characterization of dopaminergic neurons derived from rodent mesencephalic progenitor cells
    • Storch A., Lester H. A., Boehm B. O. Schwarz J. (2003) Functional characterization of dopaminergic neurons derived from rodent mesencephalic progenitor cells. J. Chem. Neuroanat. 26, 133 142.
    • (2003) J. Chem. Neuroanat. , vol.26 , pp. 133-142
    • Storch, A.1    Lester, H.A.2    Boehm, B.O.3    Schwarz, J.4
  • 70
    • 33747195353 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
    • Takahashi K. Yamanaka S. (2006) Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126, 663 676.
    • (2006) Cell , vol.126 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2
  • 71
    • 21844454972 scopus 로고    scopus 로고
    • Identification of dopaminergic neurons of nigral and ventral tegmental area subtypes in grafts of fetal ventral mesencephalon based on cell morphology, protein expression, and efferent projections
    • Thompson L., Barraud P., Andersson E., Kirik D. Bjorklund A. (2005) Identification of dopaminergic neurons of nigral and ventral tegmental area subtypes in grafts of fetal ventral mesencephalon based on cell morphology, protein expression, and efferent projections. J. Neurosci. 25, 6467 6477.
    • (2005) J. Neurosci. , vol.25 , pp. 6467-6477
    • Thompson, L.1    Barraud, P.2    Andersson, E.3    Kirik, D.4    Bjorklund, A.5
  • 72
    • 8444231365 scopus 로고    scopus 로고
    • Dopamine: The salient issue
    • Ungless M. A. (2004) Dopamine: the salient issue. Trends Neurosci. 27, 702 706.
    • (2004) Trends Neurosci. , vol.27 , pp. 702-706
    • Ungless, M.A.1
  • 74
    • 0038389745 scopus 로고    scopus 로고
    • Transcriptional control of dopamine neuron development
    • Wallen A. Perlmann T. (2003) Transcriptional control of dopamine neuron development. Ann. N Y Acad. Sci. 991, 48 60.
    • (2003) Ann. N y Acad. Sci. , vol.991 , pp. 48-60
    • Wallen, A.1    Perlmann, T.2
  • 76
    • 0042591396 scopus 로고    scopus 로고
    • Multiple domains define the expression and regulatory properties of Foxp1 forkhead transcriptional repressors
    • Wang B., Lin D., Li C. Tucker P. (2003) Multiple domains define the expression and regulatory properties of Foxp1 forkhead transcriptional repressors. J. Biol. Chem. 278, 24259 24268.
    • (2003) J. Biol. Chem. , vol.278 , pp. 24259-24268
    • Wang, B.1    Lin, D.2    Li, C.3    Tucker, P.4
  • 77
    • 0036594237 scopus 로고    scopus 로고
    • Global gene expression patterns during neural differentiation of P19 embryonic carcinoma cells
    • DOI 10.1046/j.1432-0436.2002.700409.x
    • Wei Y., Harris T. Childs G. (2002) Global gene expression patterns during neural differentiation of P19 embryonic carcinoma cells. Differentiation 70, 204 219. (Pubitemid 38230555)
    • (2002) Differentiation , vol.70 , Issue.4-5 , pp. 204-219
    • Wei, Y.1    Harris, T.2    Childs, G.3
  • 79
    • 0036678947 scopus 로고    scopus 로고
    • Transient changes in mesolimbic dopamine and their association with 'reward'
    • Wightman R. M. Robinson D. L. (2002) Transient changes in mesolimbic dopamine and their association with 'reward'. J. Neurochem. 82, 721 735.
    • (2002) J. Neurochem. , vol.82 , pp. 721-735
    • Wightman, R.M.1    Robinson, D.L.2
  • 80
    • 0346220073 scopus 로고    scopus 로고
    • Defined conditions for neural commitment and differentiation
    • Ying Q. L. Smith A. G. (2003) Defined conditions for neural commitment and differentiation. Methods Enzymol. 365, 327 341.
    • (2003) Methods Enzymol. , vol.365 , pp. 327-341
    • Ying, Q.L.1    Smith, A.G.2
  • 81
    • 0037313844 scopus 로고    scopus 로고
    • Conversion of embryonic stem cells into neuroectodermal precursors in adherent monoculture
    • Ying Q. L., Stavridis M., Griffiths D., Li M. Smith A. (2003) Conversion of embryonic stem cells into neuroectodermal precursors in adherent monoculture. Nat. Biotechnol. 21, 183 186.
    • (2003) Nat. Biotechnol. , vol.21 , pp. 183-186
    • Ying, Q.L.1    Stavridis, M.2    Griffiths, D.3    Li, M.4    Smith, A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.