Hormonal regulation of pro-inflammatory and lipid peroxidation processes in liver of old ovariectomizedfemale rats

Biogerontology

Volumn 11, Issue 2, 2010, Pages 229-243

  Kireev, R A ^a   Tresguerres, A C F ^b   Garcia, C ^b   Borras, C ^c   Ariznavarreta, C ^b   Vara, E ^b   Vina, J ^c   Tresguerres, J A F ^b  

^a INSTITUTE OF GENERAL PATHOLOGY AND PATHOPHYSIOLOGY   (Russian Federation)

^b UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^c UNIVERSITY OF VALENCIA   (Spain)

Author keywords

Aging; Hormones Introduction; Inflammation; Liver; Oxidative markers

Indexed keywords

ESTRADIOL VALERATE; ESTROGEN; GROWTH HORMONE; HEME OXYGENASE 1; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; ISOFLAVONE; LIPID PEROXIDE; NITRIC OXIDE; PHYTOESTROGEN; PHYTOSOYA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

AGING; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHRONIC DRUG ADMINISTRATION; CONTROLLED STUDY; DRUG MECHANISM; FEMALE; HEPATITIS; HORMONAL REGULATION; HORMONE SUBSTITUTION; LIPID PEROXIDATION; LIVER INJURY; NONHUMAN; OVARIECTOMY; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; RAT; UPREGULATION; WESTERN BLOTTING;

AGING; ANIMALS; CYTOKINES; ESTROGENS; FEMALE; GROWTH HORMONE; HEME OXYGENASE-1; INFLAMMATION; LIPID PEROXIDATION; LIPID PEROXIDES; LIVER; MODELS, ANIMAL; NITRIC OXIDE SYNTHASE TYPE II; OVARIECTOMY; OXIDATIVE STRESS; PHYTOESTROGENS; RATS; RATS, WISTAR;

EID: 77950859629     PISSN: 13895729     EISSN: 15736768     Source Type: Journal    
DOI: 10.1007/s10522-009-9242-2     Document Type: Article

References (70)

1. Alm P, Ekstrom P, Henningsson R, Lundquist I (1999) Morphological evidence for the existence of nitric oxide and carbon monoxide pathways in the rat islets of Langerhans: an immunocytochemical and confocal microscopical study. Diabetologia 42:978-986
2. Arora A, Nair MG, Strasburg GM (1998) Structure-activity relationships for antioxidant activities of a series of flavonoids in a liposomal system. Free Radic Biol Med 24:1355-1363 (Pubitemid 28270336)
3. Ayala A, Perrin MM, Ertel W, Chaudry IH (1992) Differential effects of haemorrhage on Kupffer cells: decreased antigen presentation despite increased inflammatory cytokine (IL- 1, IL-6 and TNF) release. Cytokine 4:66-75
4. Berg G, Ekerfelt C, Hammar M, Lindgren R, Matthisen L, Ernerudh C (2002) Cytokine changes in postmenopausal women treated with estrogen: a placebo-controlled study. Am J Reprod Immunol 48:63-69
5. Bresson JL, Jeay S, Gagnerault MC, Kayser C, Beressi N, Wu Z, Kinet S, Dardenne M, Postel-Vinay MC (1999) Growth hormone (GH) and prolactin receptors in human peripheral blood mononuclear cells: relation with age and GHbinding protein. Endocrinology 140:3203-3209
6. Carlson S, Peng N, Prasain JK, Wyss JM (2008) Effects of botanical dietary supplements on cardiovascular, cognitive, and metabolic function in males and females. Gend Med 5:76-90
7. Castillo C, Salazar V, Ariznavarreta C, Vara E, Tresguerres JA (2004) Effect of recombinant human growth hormone on age-related hepatocyte changes in old male and female Wistar rats. Endocr 25:33-39
8. Castillo C, Salazar V, Ariznavarreta C, Vara E, Tresguerres JAF (2005) Effect of growth hormone and estrogen administration on hepatocyte alterations in old ovariectomized female Wistar rats. Endocr 26:11-18 (Pubitemid 41271111)
9. Castillo C, Salazar V, Ariznavarreta C, Vara E, Tresguerres JAF (2006) Effect of isoflavone administration on agerelated hepatocytes changes in old ovariectomized female Wistar rats. Phytomedicine 13:468-476
10. Cho JY, Kim PS, Park J, Yoo ES, Baik KU, Kim Y-K et al (2000) Inhibitor of tumor necrosis factor-α production in lipopolysaccharide-stimulated RAW 264.7 cells from Amorpha fruticosa. J Ethnopharmacol 70:127-133
11. Chung HY, Jung KJ, Yu BP (2005) Molecular inflammation as an underlying mechanism of aging: The anti-inflammatory action of calorie restriction. In: Surh YJ, Packer L (eds) Oxidative stress, inflammation and health. Marcel Dekker, NY, pp 387-419
12. Cioffi M, Esposito K, Vietri MT, Gazzerro P, D'Auria A, Ardovino I et al (2002) Cytokine pattern in postmenopause. Maturitas 41:187-192
13. Dhainaut JF, Marin N, Mignon A, Vinsonneau C (2001) Hepatic response to sepsis: interaction between coagulation and inflammatory processes. Crit Care Med 29:42-47
14. Ferrucci L, Ble A, Bandinelli S, Lauretani F, Suthers K, Guralnik JM (2004) A flame burning within. Aging Clin Exp Res 16:240-243
15. Franco C, Andersson B, Lonn L, Bengtsson BA, Svensson J, Johannsson G (2007) Growth hormone reduced inflammation in postmenopausal women with abdominal obesity: a 12 month, randomized, placebo-control trial. J Clin Endocrinol Metab 92:2644-2647
16. Gagliano N, Grizzi F, Annoni G (2007) Mechanisms of aging and liver function. Dig Dis 25(2):118-123
17. Haeffner N, Thieblemont N, Deas O, Marelli O, Charpentier B, Senik A, Wright SD, Cavaillon N, Hirsh F (1997) Inhibitory effect of growth hormone on TNF-alpha secretion and nuclear factor-kB translocation in lipopolysaccharidestimulated human monocytes. J Immunol 158:1310-1314
18. Hilmer SN, Cogger VC, Le Couteur DG (2007) Basal activity of Kupffer cells increases with old age. J Gerontol A Biol Sci Med Sci 62:973-978
19. Ho KM, Ny L, Mcmurray G et al (1999) Co-localization of carbon monoxide and nitric oxide synthesizing enzymes in the human urethral sphincter. J Urol 161:1968-1972
20. Hori R, Kashiba M, Toma T, Yachie A, Goda N, Makino N, Soejima A, Nagasawa T, Nakabayashi K, Suematsu M (2002) Gene transfection of H25A mutant heme oxygenase-1 protects cells against hydroperoxide-induced cytotoxicity. J Biol Chem 277:10712-10718
21. Inaba K, Suzuki S, Ihara H, Sakaguchi T, Baba S, Urano T, Konno H, Nakamura S (2005) Sexual dimorphism in endotoxin susceptibility after partial hepatectomy in rats. J Hepatol 42:719-727
22. Jeay S, Sonenshein GE, Postel-Vinay MC, Baixeras E (2000) Growth hormone prevents apoptosis through activation of NF-kB in interleukin-3-dependent Ba/F3 cell line. Mol Endocrinol 14:650-661
23. Jeschke MG, Barrow RE, Herndon DN (2000) Recombinant human growth hormone treatment in pediatric burn patients and its role during the hepatic acute phase response. Crit Care Med 28:1578-1584
24. Kamada M, Irahara M, Maegawa M et al (2001) Postmenopausal changes in serum cytokine levels and hormone replacement therapy. Am J Obstet Gynecol 184:309-314 (Pubitemid 32206977)
25. Kankofer M, Radzki RP, Bienko M, Albera E (2007) Antioxidative/ oxidative status of rat liver after ovariectomy. J Vet Med A Physiol Pathol Clin Med 54:225-229
26. Karbownik-Lewinska M, Kokoszko A, Lewandowski KC, Shalet SM, Lewinski A (2008) GH replacement reduces increased lipid peroxidation in GH-deficient adults. Clin Endocrinol 68:957-964
27. Kireev RA, Tresguerres AF, Vara E, Ariznavarreta C, Tresguerres JA (2007) Effect of chronic treatments with GH, melatonin, estrogens, and phytoestrogens on oxidative stress parameters in liver from aged female rats. Biogerontology 8(5):469-482
28. Kooijman R, Hooghe-Peters EL, Hooghe R (1996) Prolactin, growth hormone, and insulin-like growth factor-I in the immune system. Adv Immunol 63:377-454
29. Krakauer T, Li BQ, Young HA (2001) The flavonoid baicalin inhibits superantigen-induced inflammatory cytokines and chemokines. FEBS Lett 500:52-55
30. Kroncke KD, Fehsel K, Kolb-Bachofen V (1998) Inducible nitric oxide synthase in human diseases. Clin Exp Immunol 113:147-156
31. Kumru S, Godekmerdan A, Yilmaz B (2004) Immune effects of surgical menopause and estrogen replacement therapy in peri-menopausal women. J Reprod Immunol 63:31-38
32. Leclercq IA, Farell GC, Sempoux C, De la Pena A, Horsmans Y (2004) Curcumin inhibits NF-kB activation and reduces the severity of experimental steatohepatitis in mice. J Hepatol 41:926-934
33. Lee YM, Cheng PY, Hong SF et al (2005) Oxidative stress induces vascular heme oxygenase-1 expression in ovariectomized rats. Free Radic Biol Med 39:108-117
34. Liu Y, Shimizu I, Omoya T, Ito S, Gu XS, Zuo J (2002) Protective effect of estradiol on hepatocytic oxidative damage. World J Gastroenterol 8:363-366
35. Luedde T, Trautwein C (2006) Intracellular survival pathways in the liver. Liver Int 26:1163-1174
36. Luedde T, Liedtke C, Manns MP, Trautwein C (2002) Losing balance: cytokine signalling and cell death in the context of hepatocyte injury and hepatic failure. Eur Cytokine Netw 13:377-383
37. Martínez-Flórez S, Gutiérrez MB, Sánchez-Campos S, González-Gallego J, Tuñón MJ (2005) Quercetin prevents nitric oxide production and nuclear factor kappa B activation in interleukin-1β-activated rat hepatocytes. J Nutr 135:1359-1365
38. Mester M, Carter EA, Tompkins RG et al (1994) Thermal injury induces very early production of interleukin-1 alpha in the rat by mechanisms other than endotoxemia. Surgery 115:588-596
39. Morales AI, Vicente-Sánchez C, Jerkic M, Santiago JM, Sánchez- González PD, Pérez-Barriocanal F, López Novoa JM (2006) Effect of quercetin on metallothionein, nitric oxide synthases and cyclooxygenase-2 expression on experimental chronic cadmium nephrotoxicity in rats. Toxicol Appl Pharmacol 210:128-135
40. Moutsatsou P (2007) The spectrum of phytoestrogens in nature: our knowledge is expanding. Hormones (Athens) 6(3):173-193
41. Nagai H, Matsumaru K, Feng G, Kaplowitz N (2002) Reduced glutathione depletion causes necrosis and sensitization to tumor necrosis factor-alpha-induced apoptosis in cultured mouse hepatocytes. Hepatology 36:55-64
42. Nanji AA, Jokelainen K, Tipoe GL, Rahemtulla A, Thomas P, Dannenberg AJ (2003) Curcumin prevents alcoholinduced liver disease in rats by inhibiting the expression of NF-kB-dependent genes. Am J Physiol Gastrointest Liver Physiol 284:321-327
43. Nesibe A, Nursen Y (2007) TNF-a levels in children with growth hormone deficiency and the effect of long-term growth hormone replacement therapy. Growth Hormon IGF Res 17:149-153
44. Pang JL, Ricupero DA, Huang S, Fatma N, Sing DP, Romero JS, Chattopadhyay N (2006) Differential activity of kaempferol and quercetin in attenuating tumor necrosis factor receptor family signaling in bone cells. Biochem Pharmacol 71:818-886
45. Polan ML, Loukides J, Nelson P, Carding S, Diamond M, Walsh A, Bottomly K (1989) Progesterone and estradiol modulate interleukin 1-beta messenger ribonucleic acid levels in cultured human peripheral monocytes. J Clin Endocrinol Metab 69:1200-1206
46. Rachon D, Mysliwska J, Suchecka-Rachon K, Wieckiewicz J, Mysliwski A (2002) Effects of oestrogen deprivation on interleukin-6 production by peripheral blood mononuclear cells of postmenopausal women. J Endocrinol 172:387-395
47. Ray A, Prefontaine KE, Ray P (1994) Down-modulation of interleukin-6 gene expression by 17b-estradiol in the absence of high affinity DNA binding by the estrogen receptor. J Biol Chem 269:12940-12946
48. Sabharwal P, Varma S (1996) Growth hormone synthesized and secreted by human thymocytes acts via insulin-like growth factor I as an autocrine and paracrine growth factor. J Clin Endocrinol Metab 81:2663-2669
49. Saucedo R, Rico G, Basutro L, Ochoa R, Zarafe A (2002) Transdermal estradiol in menopausal women depresses interleukin-6 without effecting other markers of immune response. Gynecol Obstet Invest 53:114-117
50. Scacchi M, Valassi E, Pincelli AI, Fatti LM, Pecori Giraldi F, Ascoli P, Viarengo R, Cestaro B, Cavagnini F, Cazzola R (2006) Increased lipid peroxidation in adult GH-deficient patients: effects of short-term GH administration. J Endocrinol Invest 29:899-904
51. Seiva FRF, Ebaid GMX, Castro AVB et al (2008) Growth hormone and heart failure: oxidative stress and energetic metabolism in rats. Growth Hormon IGF Res 18:275-283
52. Sener G, Arbak S, Kurtaran P, Gedik N, Yegen BC (2005) Estrogen protects the liver and intestines against sepsisinduced injury in rats. J Surg Res 128(1):70-78
53. Shimizu I (2003) Impact of oestrogens on the progression of liver disease. Liver Int 23:63-69
54. Shiraishi T, Shimizu I, Itagaki T, Urata M, Tamaki K et al (2006) Inhibitory effects of estrogen on chemokine and proinflammatory cytokine production in mononuclear cells and macrophages [abstract]. Gastroenterology 150:A-793
55. Stachlewitz RF, Seabra V, Bradford B et al (1999) Glycine and uridine prevent d-galactosamine hepatotoxicity in the rat: role of Kupffer cells. Hepatology 29:737-745
56. Sugihara N, Arakawa T, Ohnishi M, Furuno K (1999) Anti-and prooxidative effects of flavonoids on metal-induced lipid hydroperoxide-dependent lipid peroxidation in cultured hepatocytes loaded with alpha-linoleic acid. Free Radic Biol Med 27:1313-1323
57. Suschek CV, Schnorr O, Kolb-Bachofen V (2004) The role of iNOS in chronic inflammatory processes in vivo: is it damage-promoting, protective, or active at all? Curr. Mol. Med. 4:763-775
58. Suzuki S, Toledo-Pereyra LH (1994) Interleukin 1 and tumor necrosis factor production as the initial stimulants of liver ischemia and reperfusion injury. J Surg Res 57:253-258
59. US Preventive Services Task Force (2002) Postmenopausal hormone replacement therapy for primary prevention of chronic conditions: recommendations and rationale. Ann Intern Med 137:834-839
60. Verstraeten SV, Keen CL, Schmitz HH, Fraga CG, Oteiza PI (2003) Flavan-3-ols and procyanidins protect liposomes against lipid oxidation and disruption of the bilayer structure. Free Radic Biol Med 34:84-92
61. Vom Saal FS, Finch CE, Nelson JF (1994) Natural history and mechanisms of reproductive aging in humans, laboratory rodents and other selected vertebrates. In: Knobil E, Neill JD (eds) The physiology of reproduction, 2nd edn. Raven Press, NY, pp 1213-1314
62. Vural P, Akgul C, Canbaz M (2005) Effects of menopause and tibolone on antioxidants in postmenopausal women. Ann Clin Biochem 42:220-223
63. Wadsworth TL, Koop DR (2001) Effects of Ginkgo biloba extract (EGb 761) and quercetin on lipopolysaccharideinduced release of nitric oxide. Chem Biol Interact 137:43-58
64. Wadsworth TL, McDonald TL, Koop DR (2001) Effects of Ginkgo biloba extract (EGb 761) and quercetin on lipopolysaccharide induced signaling pathways involved in the release of tumor necrosis factor-a. Biochem Pharmacol 62:963-974
65. Wagener FA, van Beurden HE, von den Hoff JW, Adema G, Figdor CG (2003) The heme-heme oxygenase system: a molecular switch in wound healing. Blood 102:521-528
66. Wang S, DeGroff VL, Clinton SK (2003) Tomato and soy polyphenols reduce insulin-like growth factor-I-stimulated prostate cancer cell proliferation and apoptotic resistance in vitro via inhibition of intracellular signaling pathways involving tyrosine kinase. J Nutr 133:2367-2376
67. Wong MCY, Portmann B, Sherwood R, Niemela O, Koivisto H, Parkkila S et al (2007) The cytoprotective effect of a-tocopherol and daidzein against D-galactosamine-induced oxidative damage in the rat liver. Metab Clin Exp 56:865-875
68. Yagi K (1997) Female hormones act as natural antioxidants asurvey of our research. Acta Biochim Pol 44:701-709
69. Yasuda M, Shimizu I, Shiba M, Ito S (1999) Suppressive effects of estradiol on dimethylnitrosamine-induced fibrosis in the liver in rats. Hepatology 29:719-727 (Pubitemid 29109585)
70. Yasui T, Maegawa M, Tomita J, Miyatani Y, Yamada M et al (2007) Changes in serum cytokine concentrations during the menopausal transition. Maturitas 56:396-403 (Pubitemid 46401105)