메뉴 건너뛰기




Volumn 13, Issue 4, 2002, Pages 377-383

Losing balance: Cytokine signaling and cell death in the context of hepatocyte injury and hepatic failure

Author keywords

Apoptosis; Fas; Interleukin 6; Liver failure; NF KB; Tumor necrosis factor

Indexed keywords

CYTOCHROME C; CYTOKINE; FAS LIGAND; INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA;

EID: 0036825005     PISSN: 11485493     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (38)

References (70)
  • 1
    • 0027293230 scopus 로고
    • Acute liver failure: Redefining the syndromes
    • O'Grady JG, Schalm SW, Williams R. 1993. Acute liver failure: redefining the syndromes. Lancet 342: 273.
    • (1993) Lancet , vol.342 , pp. 273
    • O'Grady, J.G.1    Schalm, S.W.2    Williams, R.3
  • 2
    • 0036184310 scopus 로고    scopus 로고
    • Acute-on-chronic liver failure: Pathophysiological basis of therapeutic options
    • Jalan R, Williams R. 2002. Acute-on-chronic Liver Failure: Pathophysiological Basis of Therapeutic Options. Blood Purif. 20: 252.
    • (2002) Blood Purif. , vol.20 , pp. 252
    • Jalan, R.1    Williams, R.2
  • 3
    • 0035094345 scopus 로고    scopus 로고
    • Clinical management of acute hepatic failure
    • Rahman T, Hodgson H. 2001. Clinical Management of acute hepatic failure (Review). Intensive Care Med. 27: 467.
    • (2001) Intensive Care Med. , vol.27 , pp. 467
    • Rahman, T.1    Hodgson, H.2
  • 4
    • 0032897568 scopus 로고    scopus 로고
    • Mechanisms of hepatic toxicity V. Necrapoptosis and the mitochondrial permeability transition: Shared pathways to necrosis and apoptosis
    • Lemasters JJ. 1999. Mechanisms of Hepatic Toxicity V. Necrapoptosis and the mitochondrial permeability transition: shared pathways to necrosis and apoptosis (Review). Am. J. Physiol. 276: G1.
    • (1999) Am. J. Physiol. , vol.276
    • Lemasters, J.J.1
  • 5
    • 0015383455 scopus 로고
    • Apoptosis, a basic biological phenomenon with wide-ranging implications in tissue kinetics
    • Kerr JF, Wyllie AH, Currie AR. 1972. Apoptosis, a basic biological phenomenon with wide-ranging implications in tissue kinetics (Review). Br. J. Cancer 26: 239.
    • (1972) Br. J. Cancer , vol.26 , pp. 239
    • Kerr, J.F.1    Wyllie, A.H.2    Currie, A.R.3
  • 6
    • 0028891783 scopus 로고
    • Apoptosis, oncosis, and necrosis. An overview of cell death
    • Majno G, Joris I. 1995. Apoptosis, oncosis, and necrosis. An overview of cell death (Review). Am. J. Pathol. 146: 3.
    • (1995) Am. J. Pathol. , vol.146 , pp. 3
    • Majno, G.1    Joris, I.2
  • 7
    • 0030702084 scopus 로고    scopus 로고
    • Caspases: Intracellular signaling by proteolysis
    • Salvesen GS, Dixit VM. 1997. Caspases: intracellular signaling by proteolysis (Review). Cell 91: 443.
    • (1997) Cell , vol.91 , pp. 443
    • Salvesen, G.S.1    Dixit, V.M.2
  • 8
    • 0035035052 scopus 로고    scopus 로고
    • Apoptosis in diseases of the liver
    • Neuman MG. 2001. Apoptosis in diseases of the liver (Review). Crit. Rev. Clin. Lab. Sci. 38: 109.
    • (2001) Crit. Rev. Clin. Lab. Sci. , vol.38 , pp. 109
    • Neuman, M.G.1
  • 9
    • 0029294613 scopus 로고
    • In situ detection of fragmented DNA (TUNEL-assay) fails to discriminate among apoptosis, necrosis, and autolytic cell death: A cautionary note
    • Grasl-Kraupp B, Ruttkay-Nedecky H, Koudelka H, Bukowska K, Bursch W, Schulte-Herrmann R. 1995. In situ detection of fragmented DNA (TUNEL-assay) fails to discriminate among apoptosis, necrosis, and autolytic cell death: a cautionary note. Hepatology 21: 1465.
    • (1995) Hepatology , vol.21 , pp. 1465
    • Grasl-Kraupp, B.1    Ruttkay-Nedecky, H.2    Koudelka, H.3    Bukowska, K.4    Bursch, W.5    Schulte-Herrmann, R.6
  • 10
    • 0033556544 scopus 로고    scopus 로고
    • The mitochondrial permeability transition mediates both necrotic and apoptotic death of hepatocytes exposed to Br-A23187
    • Qian T, Herman B, Lemasters JJ. 1999. The mitochondrial permeability transition mediates both necrotic and apoptotic death of hepatocytes exposed to Br-A23187. Toxicol. Appl. Pharmacol. 154: 117.
    • (1999) Toxicol. Appl. Pharmacol. , vol.154 , pp. 117
    • Qian, T.1    Herman, B.2    Lemasters, J.J.3
  • 11
    • 0035966059 scopus 로고    scopus 로고
    • Anti-Fas induces hepatic chemokines and promotes inflammation by an NF-kB-independent, caspase-3-dependent pathway
    • Faouzi S, Burckhardt BE, Hanson JC, Campe CB, Schrum LW, Rippe RA, Maher JJ. 2001. Anti-Fas induces hepatic chemokines and promotes inflammation by an NF-kB-independent, caspase-3-dependent pathway. J. Biol. Chem. 276: 49077.
    • (2001) J. Biol. Chem. , vol.276 , pp. 49077
    • Faouzi, S.1    Burckhardt, B.E.2    Hanson, J.C.3    Campe, C.B.4    Schrum, L.W.5    Rippe, R.A.6    Maher, J.J.7
  • 14
    • 0033491193 scopus 로고    scopus 로고
    • CD95 (APO-1/Fas)-mediated apoptosis: Live and let die
    • Krammer PH. 1999. CD95 (APO-1/Fas)-mediated apoptosis: live and let die (Review). Adv. Immunol. 71: 163.
    • (1999) Adv. Immunol. , vol.71 , pp. 163
    • Krammer, P.H.1
  • 15
    • 0031950395 scopus 로고    scopus 로고
    • CD95-induced apoptosis in human liver disease
    • Galle PR, Krammer PH. 1998. CD95-induced apoptosis in human liver disease (Review). Semin. Liver. Dis. 18: 141.
    • (1998) Semin. Liver. Dis. , vol.18 , pp. 141
    • Galle, P.R.1    Krammer, P.H.2
  • 16
    • 0030699185 scopus 로고    scopus 로고
    • Reactive oxygen intermediates are involved in the induction of CD95 ligand mRNA expression by cytostatic drugs in hepatoma cells
    • Hug H, Strand S, Grambihler A, Galle J, Hack V, Stremmel W, Krammer PH, Galle PR. 1997. Reactive oxygen intermediates are involved in the induction of CD95 ligand mRNA expression by cytostatic drugs in hepatoma cells. J. Biol. Chem. 272: 28191.
    • (1997) J. Biol. Chem. , vol.272 , pp. 28191
    • Hug, H.1    Strand, S.2    Grambihler, A.3    Galle, J.4    Hack, V.5    Stremmel, W.6    Krammer, P.H.7    Galle, P.R.8
  • 19
    • 0033561109 scopus 로고    scopus 로고
    • Apoptosis and the expression of Fas and Fas ligand (FasL) antigen in rejection and reinfection in liver allograft specimens
    • Tannapfel A, Kohlhaw K, Ebelt J, Hauss J, Liebert U, Berr F, Wittekind C. 1999. Apoptosis and the expression of Fas and Fas ligand (FasL) antigen in rejection and reinfection in liver allograft specimens. Transplantation 67: 1079.
    • (1999) Transplantation , vol.67 , pp. 1079
    • Tannapfel, A.1    Kohlhaw, K.2    Ebelt, J.3    Hauss, J.4    Liebert, U.5    Berr, F.6    Wittekind, C.7
  • 22
    • 0033735804 scopus 로고    scopus 로고
    • Protection against Fas receptor-mediated apoptosis in hepatocytes and nonparenchymal cells by a caspase-8 inhibitor in vivo: Evidence for a postmitochondrial processing of caspase-8
    • Bajt ML, Lawson JA, Vonderfecht SL, Gujral JS, Jaeschke H. 2000. Protection against Fas receptor-mediated apoptosis in hepatocytes and nonparenchymal cells by a caspase-8 inhibitor in vivo: evidence for a postmitochondrial processing of caspase-8. Toxicol. Sci. 58: 109.
    • (2000) Toxicol. Sci. , vol.58 , pp. 109
    • Bajt, M.L.1    Lawson, J.A.2    Vonderfecht, S.L.3    Gujral, J.S.4    Jaeschke, H.5
  • 25
    • 0023684531 scopus 로고
    • A phase I trial of intravenously-administered recombinant tumor necrosis factor-alpha in cancer patients
    • Feinberg B, Kurzrock R, Talpaz M, Blick M, Saks S, Gutterman JU. 1988. A phase I trial of intravenously-administered recombinant tumor necrosis factor-alpha in cancer patients. J. Clin. Oncol. 6: 1328.
    • (1988) J. Clin. Oncol. , vol.6 , pp. 1328
    • Feinberg, B.1    Kurzrock, R.2    Talpaz, M.3    Blick, M.4    Saks, S.5    Gutterman, J.U.6
  • 34
    • 0028795171 scopus 로고
    • Concavalin A-induced T-cell-mediated hepatic injury in mice: The role of tumor necrosis factor
    • Gantner F, Leist M, Lohse AW, Germann PG, Tiegs G. 1995. Concavalin A-induced T-cell-mediated hepatic injury in mice: the role of tumor necrosis factor. Hepatology 21: 190.
    • (1995) Hepatology , vol.21 , pp. 190
    • Gantner, F.1    Leist, M.2    Lohse, A.W.3    Germann, P.G.4    Tiegs, G.5
  • 35
    • 0029125701 scopus 로고
    • Protease activation during apoptosis: Death by a thousand cuts ?
    • Review
    • Martin SJ, Green DR. 1995. Protease activation during apoptosis: death by a thousand cuts ? (Review) Cell. 82: 349.
    • (1995) Cell. , vol.82 , pp. 349
    • Martin, S.J.1    Green, D.R.2
  • 36
    • 0033575255 scopus 로고    scopus 로고
    • Suicidal tendencies: Apoptotic cell death by caspase family proteinases
    • Wolf BB, Green DR. 1999. Suicidal tendencies: apoptotic cell death by caspase family proteinases (Review). J. Biol. Chem. 274: 20049.
    • (1999) J. Biol. Chem. , vol.274 , pp. 20049
    • Wolf, B.B.1    Green, D.R.2
  • 37
    • 0032575714 scopus 로고    scopus 로고
    • Death receptors: Signaling and modulation
    • Ashkenazi A, Dixit VM. 1998. Death receptors: signaling and modulation (Review). Science 281: 1305.
    • (1998) Science , vol.281 , pp. 1305
    • Ashkenazi, A.1    Dixit, V.M.2
  • 38
    • 0029007855 scopus 로고
    • The TNF receptor 1-associated protein TRADD signals cell death and NF-κB activation
    • Hsu H, Xiong J, Goeddel DV. 1995. The TNF receptor 1-associated protein TRADD signals cell death and NF-κB activation. Cell. 81: 495.
    • (1995) Cell. , vol.81 , pp. 495
    • Hsu, H.1    Xiong, J.2    Goeddel, D.V.3
  • 39
    • 0029884711 scopus 로고    scopus 로고
    • Bcl-2 blocks loss of mitochondrial membrane potential while ICE inhibitors act at a different step during inhibition of death induced by respiratory chain inhibitors
    • Shimizu S, Eguchi Y, Kamiike W, Waguri S, Uchiyama Y, Matsuda H, Tsujimoto Y. 1996. Bcl-2 blocks loss of mitochondrial membrane potential while ICE inhibitors act at a different step during inhibition of death induced by respiratory chain inhibitors. Oncogene 13: 21.
    • (1996) Oncogene , vol.13 , pp. 21
    • Shimizu, S.1    Eguchi, Y.2    Kamiike, W.3    Waguri, S.4    Uchiyama, Y.5    Matsuda, H.6    Tsujimoto, Y.7
  • 41
    • 0032555716 scopus 로고    scopus 로고
    • Bid, a Bcl-2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors
    • Luo X, Budihardjo I, Zou H, Slaughter C, Wang X. 1998. Bid, a Bcl-2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors. Cell. 94: 481.
    • (1998) Cell. , vol.94 , pp. 481
    • Luo, X.1    Budihardjo, I.2    Zou, H.3    Slaughter, C.4    Wang, X.5
  • 42
    • 0032555697 scopus 로고    scopus 로고
    • Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis
    • Li H, Zhu H, Xu CJ, Yuan J. 1998. Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis. Cell. 94: 491.
    • (1998) Cell. , vol.94 , pp. 491
    • Li, H.1    Zhu, H.2    Xu, C.J.3    Yuan, J.4
  • 43
    • 0029116916 scopus 로고
    • The mitochondrial permeability transition
    • Zoratti M, Szabo I. 1995. The mitochondrial permeability transition (Review). Biochim. Biophys. Acta 1241: 139.
    • (1995) Biochim. Biophys. Acta , vol.1241 , pp. 139
    • Zoratti, M.1    Szabo, I.2
  • 45
    • 0031772126 scopus 로고    scopus 로고
    • The mitochondrial permeability transition is required for tumor necorsis factor alpha-mediated apoptosis and cytochrome c release
    • Bradham CA, Qian T, Streetz K, Trautwein C, Brenner DA, Lemasters JJ. 1998. The mitochondrial permeability transition is required for tumor necorsis factor alpha-mediated apoptosis and cytochrome c release. Mol. Cell. Biol. 18: 6353.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 6353
    • Bradham, C.A.1    Qian, T.2    Streetz, K.3    Trautwein, C.4    Brenner, D.A.5    Lemasters, J.J.6
  • 47
    • 0030032106 scopus 로고    scopus 로고
    • TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways
    • Hsu H, Shu HB, Pan MG, Goeddel DV. 1996. TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways. Cell. 84: 299.
    • (1996) Cell. , vol.84 , pp. 299
    • Hsu, H.1    Shu, H.B.2    Pan, M.G.3    Goeddel, D.V.4
  • 48
    • 0036009115 scopus 로고    scopus 로고
    • NF-κB at the crossroads of life and death
    • Karin M, Lin A. 2002. 2002. NF-κB at the crossroads of life and death (Review). Nat. Immunol. 3: 221.
    • (2002) Nat. Immunol. , vol.3 , pp. 221
    • Karin, M.1    Lin, A.2
  • 50
    • 0030298294 scopus 로고    scopus 로고
    • Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis, while NF-κB activation prevents cell death
    • Liu ZG, Hsu H, Goeddel DV, Karin M. 1996. Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis, while NF-κB activation prevents cell death. Cell. 87: 565.
    • (1996) Cell. , vol.87 , pp. 565
    • Liu, Z.G.1    Hsu, H.2    Goeddel, D.V.3    Karin, M.4
  • 51
    • 0027998359 scopus 로고
    • Murine hepatocyte apoptosis induced in vitro and in vivo by TNF-alpha requires transcriptional arrest
    • Leist M, Gantner F, Bohlinger I, Germann PG, Tiegs G, Wendel A. 1994. Murine hepatocyte apoptosis induced in vitro and in vivo by TNF-alpha requires transcriptional arrest. J. Immunol. 153: 1778.
    • (1994) J. Immunol. , vol.153 , pp. 1778
    • Leist, M.1    Gantner, F.2    Bohlinger, I.3    Germann, P.G.4    Tiegs, G.5    Wendel, A.6
  • 52
    • 0036199932 scopus 로고    scopus 로고
    • Apoptosis and NF-kB: The FADD connection
    • Duckett CS. 2002. Apoptosis and NF-kB: the FADD connection. J. Clin. Invest. 109: 579.
    • (2002) J. Clin. Invest. , vol.109 , pp. 579
    • Duckett, C.S.1
  • 53
    • 0036172129 scopus 로고    scopus 로고
    • The Fas-associated death domain protein suppresses activation of NF-kappa B by LPS and IL-1 beta
    • Bannermann DD, Tupper JC, Kelly JD, Winn RK, Harlan JM. 2002. The Fas-associated death domain protein suppresses activation of NF-kappa B by LPS and IL-1 beta. J. Clin. Invest. 109: 419.
    • (2002) J. Clin. Invest. , vol.109 , pp. 419
    • Bannermann, D.D.1    Tupper, J.C.2    Kelly, J.D.3    Winn, R.K.4    Harlan, J.M.5
  • 54
    • 0033621839 scopus 로고    scopus 로고
    • NF-κB mediates apoptosis through transcriptional activation of Fas (CD95) in adenoviral hepatitis
    • Kuhnel F, Zender L, Paul Y, Tietze MK, Trautwein C, Manns M, Kubicka S. 2000. NF-κB mediates apoptosis through transcriptional activation of Fas (CD95) in adenoviral hepatitis. J. Biol. Chem. 275: 6421.
    • (2000) J. Biol. Chem. , vol.275 , pp. 6421
    • Kuhnel, F.1    Zender, L.2    Paul, Y.3    Tietze, M.K.4    Trautwein, C.5    Manns, M.6    Kubicka, S.7
  • 58
    • 0036009411 scopus 로고    scopus 로고
    • NF-κB inhibition sensitizes hepatocytes to TNF-induced apoptosis through a sustained activation of JNK and c-Jun
    • Liu H, Lo CR, Czaja MJ. 2002. NF-κB inhibition sensitizes hepatocytes to TNF-induced apoptosis through a sustained activation of JNK and c-Jun. Hepatology 35: 772.
    • (2002) Hepatology , vol.35 , pp. 772
    • Liu, H.1    Lo, C.R.2    Czaja, M.J.3
  • 61
    • 0028129732 scopus 로고
    • Hepatocyte and immune system: Acute phase reaction as a contribution to early defence mechanisms
    • Trautwein C, Boker K, Manns MP. 1994. Hepatocyte and immune system: acute phase reaction as a contribution to early defence mechanisms (Review). Gut 35: 1163.
    • (1994) Gut , vol.35 , pp. 1163
    • Trautwein, C.1    Boker, K.2    Manns, M.P.3
  • 62
    • 0030000589 scopus 로고    scopus 로고
    • STAT3 participates in transcriptional activation of the C-reactive protein gene by interleukin-6
    • Zhang D, Sun M, Samols D, Kushner I. 1996. STAT3 participates in transcriptional activation of the C-reactive protein gene by interleukin-6. J. Biol. Chem. 271: 9503.
    • (1996) J. Biol. Chem. , vol.271 , pp. 9503
    • Zhang, D.1    Sun, M.2    Samols, D.3    Kushner, I.4
  • 64
    • 0033551802 scopus 로고    scopus 로고
    • Interleukin-6 inhibits transforming growth factor-beta-induced apoptosis through the phosphatidylinositol 3-kinase/Akt and signal transducers and activators of transcription 3 pathways
    • Chen RH, Chang MC, Su YH, Tsai YT, Kuo ML. 1999. Interleukin-6 inhibits transforming growth factor-beta-induced apoptosis through the phosphatidylinositol 3-kinase/Akt and signal transducers and activators of transcription 3 pathways. J. Biol. Chem. 274: 23013.
    • (1999) J. Biol. Chem. , vol.274 , pp. 23013
    • Chen, R.H.1    Chang, M.C.2    Su, Y.H.3    Tsai, Y.T.4    Kuo, M.L.5
  • 66
    • 0031977811 scopus 로고    scopus 로고
    • Interleukin-6 spillover in the peripheral circulation increases with the severity of heart failure, and the high plasma level of interleukin-6 is an important prognostic predictor in patients with congestive heart failure
    • Tsutamoto T, Hisanaga T, Wada A, Maeda K, Ohnishi M, Fukai D, Mabuchi N, Sawaki M, Kinoshita M. 1998. Interleukin-6 spillover in the peripheral circulation increases with the severity of heart failure, and the high plasma level of interleukin-6 is an important prognostic predictor in patients with congestive heart failure. J. Am. Coll. Cardiol. 31: 391.
    • (1998) J. Am. Coll. Cardiol. , vol.31 , pp. 391
    • Tsutamoto, T.1    Hisanaga, T.2    Wada, A.3    Maeda, K.4    Ohnishi, M.5    Fukai, D.6    Mabuchi, N.7    Sawaki, M.8    Kinoshita, M.9
  • 68
    • 0035884041 scopus 로고    scopus 로고
    • Differential protection with inhibitors of caspase-8 and caspase-3 in murine models of tumor necrosis factor and Fas receptor-mediated hepatocellular apoptosis
    • Bajt ML, Vonderfecht SL, Jaeschke H. 2001. Differential protection with inhibitors of caspase-8 and caspase-3 in murine models of tumor necrosis factor and Fas receptor-mediated hepatocellular apoptosis. Toxicol. Appl. Pharmacol. 175: 243.
    • (2001) Toxicol. Appl. Pharmacol. , vol.175 , pp. 243
    • Bajt, M.L.1    Vonderfecht, S.L.2    Jaeschke, H.3
  • 70
    • 0033556164 scopus 로고    scopus 로고
    • The designer cytokine hyperinterleukin-6 is a potent activator of STAT3-dependent gene transcription in vivo and in vitro
    • Rakemann T, Niehof M, Kubicka S, Fischer M, Manns MP, Rose-John S, Trautwein C. 1999. The designer cytokine hyperinterleukin-6 is a potent activator of STAT3-dependent gene transcription in vivo and in vitro. J. Biol. Chem. 274: 1257.
    • (1999) J. Biol. Chem. , vol.274 , pp. 1257
    • Rakemann, T.1    Niehof, M.2    Kubicka, S.3    Fischer, M.4    Manns, M.P.5    Rose-John, S.6    Trautwein, C.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.