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Volumn 17, Issue 8, 1999, Pages 649-654

ERK signalling in metastatic human MDA-MB-231 breast carcinoma cells is adapted to obtain high urokinase expression and rapid cell proliferation

Author keywords

Breast cancer; Cyclin D1; ERK; u PA

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; CYCLIN D1; CYCLIN DEPENDENT KINASE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; OKADAIC ACID; PROTEIN P21; UROKINASE;

EID: 0033361269     PISSN: 02620898     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1006741228402     Document Type: Article
Times cited : (41)

References (34)
  • 1
    • 0026425631 scopus 로고
    • Tumor invasion and metastasis: An imbalance of positive and negative regulation
    • 1. Liotta LA, Stetler-Stevenson WG. Tumor invasion and metastasis: an imbalance of positive and negative regulation. Cancer Res 1991; 51: 5054s-9s.
    • (1991) Cancer Res , vol.51
    • Liotta, L.A.1    Stetler-Stevenson, W.G.2
  • 2
    • 0027535914 scopus 로고
    • Biology and biochemistry of proteases in tumor invasion
    • 2. Mignatti P, Rifkin DB. Biology and biochemistry of proteases in tumor invasion. Physiol Rev 1993; 73: 161-95.
    • (1993) Physiol Rev , vol.73 , pp. 161-195
    • Mignatti, P.1    Rifkin, D.B.2
  • 3
    • 0030271098 scopus 로고    scopus 로고
    • The metastatic phenotype - Prognostic implications
    • 3. Lindblom A, Linder S. The metastatic phenotype - prognostic implications. Crit Rev Oncol/Hematol 1996; 24: 71-96.
    • (1996) Crit Rev Oncol/Hematol , vol.24 , pp. 71-96
    • Lindblom, A.1    Linder, S.2
  • 4
    • 0028295979 scopus 로고
    • Physiological consequences of loss of plasminogen activator gene function in mice
    • 4. Carmeliet P, Schoonjans L, Kieckens L et al. Physiological consequences of loss of plasminogen activator gene function in mice. Nature 1994; 368: 419-24.
    • (1994) Nature , vol.368 , pp. 419-424
    • Carmeliet, P.1    Schoonjans, L.2    Kieckens, L.3
  • 5
    • 0030788411 scopus 로고    scopus 로고
    • The urokinase-type plasminogen activator system in cancer metastasis: A review
    • 5. Andreasen P-A, Kjoøller L, Christensen L, Duffy MJ. The urokinase-type plasminogen activator system in cancer metastasis: A review. Int J Cancer 1997; 72: 1-22.
    • (1997) Int J Cancer , vol.72 , pp. 1-22
    • Andreasen, P.-A.1    Kjoøller, L.2    Christensen, L.3    Duffy, M.J.4
  • 6
    • 0031733174 scopus 로고    scopus 로고
    • Multifunctional potential of the plasminogen activation system in tumor invasion and metastasis
    • 6. Reuning U, Magdolen V, Wilhelm O et al. Multifunctional potential of the plasminogen activation system in tumor invasion and metastasis. Int J Ontol 1998; 13: 893-906.
    • (1998) Int J Ontol , vol.13 , pp. 893-906
    • Reuning, U.1    Magdolen, V.2    Wilhelm, O.3
  • 8
    • 0030010553 scopus 로고    scopus 로고
    • Involvement of a mitogen-activated protein kinase signaling pathway in the regulation of urokinase promoter activity by c-Ha-ras
    • 8. Lengyel E, Gum R, Stepp E et al. Involvement of a mitogen-activated protein kinase signaling pathway in the regulation of urokinase promoter activity by c-Ha-ras. Cell Biochem 1996; 61: 430-43.
    • (1996) Cell Biochem , vol.61 , pp. 430-443
    • Lengyel, E.1    Gum, R.2    Stepp, E.3
  • 9
    • 0032479139 scopus 로고    scopus 로고
    • The Ets-1 and Ets-2 transcription factors activate the promoters for invasion-associated urokinase and collagenase genes in response to epidermal growth factor
    • 9. Watabe T, Yoshida K, Shindoh M et al The Ets-1 and Ets-2 transcription factors activate the promoters for invasion-associated urokinase and collagenase genes in response to epidermal growth factor. Int J Cancer 1998; 77: 128-37.
    • (1998) Int J Cancer , vol.77 , pp. 128-137
    • Watabe, T.1    Yoshida, K.2    Shindoh, M.3
  • 10
    • 0033534611 scopus 로고    scopus 로고
    • Role of mitogen-activated protein kinases and c-Jun/AP-1 trans-activating activity in the regulation of protease mRNAs and the malignant phenotype in NIH 3T3 fibroblasts
    • 10. Janulis M, Silberman S, Ambegaokar A et al. Role of mitogen-activated protein kinases and c-Jun/AP-1 trans-activating activity in the regulation of protease mRNAs and the malignant phenotype in NIH 3T3 fibroblasts. J Biol Chem 1999; 274: 801-13.
    • (1999) J Biol Chem , vol.274 , pp. 801-813
    • Janulis, M.1    Silberman, S.2    Ambegaokar, A.3
  • 11
    • 0028786336 scopus 로고
    • Transcriptional regulation by MAP kinases
    • 11. Davis RJ. Transcriptional regulation by MAP kinases. Mol Reprod Dev 1995; 42: 459-67.
    • (1995) Mol Reprod Dev , vol.42 , pp. 459-467
    • Davis, R.J.1
  • 12
    • 0029906759 scopus 로고    scopus 로고
    • The stress activated protein kinase pathway
    • 12. Woodgett JR, Avruch J, Kyriakis J. The stress activated protein kinase pathway. Cancer Surv 1996; 27: 127-38.
    • (1996) Cancer Surv , vol.27 , pp. 127-138
    • Woodgett, J.R.1    Avruch, J.2    Kyriakis, J.3
  • 13
    • 0029077563 scopus 로고
    • Direct interaction between ras and the kinase domain of mitogen-activated protein kinase kinase kinase (MEKK1)
    • 13. Russell M, Lange-Carter CA, Johnson GL. Direct interaction between Ras and the kinase domain of mitogen-activated protein kinase kinase kinase (MEKK1). J Biol Chem 1995; 270: 11757-60.
    • (1995) J Biol Chem , vol.270 , pp. 11757-11760
    • Russell, M.1    Lange-Carter, C.A.2    Johnson, G.L.3
  • 14
    • 0033565976 scopus 로고    scopus 로고
    • Deregulation of the signaling pathways controlling urokinase production - Its relationship with the invasive phenotype
    • 14. Ghiso JAA, Alonso DF, Farias EF et al. Deregulation of the signaling pathways controlling urokinase production - its relationship with the invasive phenotype. Eur J Biochem 1999; 263: 295-304.
    • (1999) Eur J Biochem , vol.263 , pp. 295-304
    • Ghiso, J.A.A.1    Alonso, D.F.2    Farias, E.F.3
  • 15
    • 0030017987 scopus 로고    scopus 로고
    • Urokinase-type plasminogen activation in three human breast cancer cell lines correlates with their in vitro invasiveness
    • 15. Holst-Hansen C, Johannessen B, Hoyer-Hansen G et al. Urokinase-type plasminogen activation in three human breast cancer cell lines correlates with their in vitro invasiveness. Clin Exp Metastasis 1996; 14: 297-307.
    • (1996) Clin Exp Metastasis , vol.14 , pp. 297-307
    • Holst-Hansen, C.1    Johannessen, B.2    Hoyer-Hansen, G.3
  • 16
    • 0026518636 scopus 로고
    • Association of increased basement membrane invasiveness with absence of estrogen receptor and expression of vimentin in human breast cancer cell lines
    • 16. Thompson EW, Paik S, Brunner N et al. Association of increased basement membrane invasiveness with absence of estrogen receptor and expression of vimentin in human breast cancer cell lines. J Cell Physiol 1992; 150: 534-54.
    • (1992) J Cell Physiol , vol.150 , pp. 534-554
    • Thompson, E.W.1    Paik, S.2    Brunner, N.3
  • 17
    • 0031285250 scopus 로고    scopus 로고
    • Activation of the IκBα kinase complex by MEKK1, a kinase of the JNK pathway
    • 17. Lee FS, Hagler J, Chen ZJ, Maniatis T. Activation of the IκBα kinase complex by MEKK1, a kinase of the JNK pathway. Cell 1997; 88: 213-222.
    • (1997) Cell , vol.88 , pp. 213-222
    • Lee, F.S.1    Hagler, J.2    Chen, Z.J.3    Maniatis, T.4
  • 18
    • 0031660671 scopus 로고    scopus 로고
    • Two novel adenovirus vector systems permitting regulated protein expression in gene transfer experiments
    • 18. Molin M, Shoshan MC, Öhman K et al. Two novel adenovirus vector systems permitting regulated protein expression in gene transfer experiments. J Virol 1998; 72: 8358-61.
    • (1998) J Virol , vol.72 , pp. 8358-8361
    • Molin, M.1    Shoshan, M.C.2    Öhman, K.3
  • 20
    • 0031970570 scopus 로고    scopus 로고
    • Activation of tissue factor gene expression in breast carcinoma cells by stimulation of the RAF-ERK signalling pathway
    • 20. Zhou JN, Ljungdahl S, Shoshan M et al. Activation of tissue factor gene expression in breast carcinoma cells by stimulation of the RAF-ERK signalling pathway. Mol Carcinogen 1998; 21: 234-43.
    • (1998) Mol Carcinogen , vol.21 , pp. 234-243
    • Zhou, J.N.1    Ljungdahl, S.2    Shoshan, M.3
  • 21
    • 0027170451 scopus 로고
    • Mitogen-activated protein kinases p42mapk and p44mapk are required for fibroblast proliferation
    • 21. Pages G, Lenormand P, L'Allemain G et al. Mitogen-activated protein kinases p42mapk and p44mapk are required for fibroblast proliferation. Proc Natl Acad Sci USA 1993; 90: 8319-23.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 8319-8323
    • Pages, G.1    Lenormand, P.2    L'Allemain, G.3
  • 22
    • 0029017456 scopus 로고
    • Ras transformation results in an elevated level of cyclin D1 and acceleration of G1 progresison in NIH 3T3 cells
    • 22. Liu J-J, Chao J-R, Jiang M-C et al. Ras transformation results in an elevated level of cyclin D1 and acceleration of G1 progresison in NIH 3T3 cells. Mol Cell Biol 1995; 15: 3654-63.
    • (1995) Mol Cell Biol , vol.15 , pp. 3654-3663
    • Liu, J.-J.1    Chao, J.-R.2    Jiang, M.-C.3
  • 23
    • 0030950537 scopus 로고    scopus 로고
    • Co-operating oncogenes converge to regulate cyclin/cdk complexes
    • 23. Lloyd AC, Obermüller F, Staddon S et al. Co-operating oncogenes converge to regulate cyclin/cdk complexes. Genes Dev 1997; 11: 663-77.
    • (1997) Genes Dev , vol.11 , pp. 663-677
    • Lloyd, A.C.1    Obermüller, F.2    Staddon, S.3
  • 24
    • 0030871667 scopus 로고    scopus 로고
    • High intensity Raf signaling causes cell cycle arrest mediated by p21Cip1
    • 24. Sewing A, Wiseman B, Lloyd AC, Land H. High intensity Raf signaling causes cell cycle arrest mediated by p21Cip1. Mol Cell Biol 1997; 17: 5588-97.
    • (1997) Mol Cell Biol , vol.17 , pp. 5588-5597
    • Sewing, A.1    Wiseman, B.2    Lloyd, A.C.3    Land, H.4
  • 25
    • 0032495589 scopus 로고    scopus 로고
    • The role of MAP kinase in TPA-mediated cell cycle arrest of human breast cancer cells
    • 25. Alblas J, Slager-Davidov R, Steenbergh PH et al. The role of MAP kinase in TPA-mediated cell cycle arrest of human breast cancer cells. Oncogene 1998; 16: 131-9.
    • (1998) Oncogene , vol.16 , pp. 131-139
    • Alblas, J.1    Slager-Davidov, R.2    Steenbergh, P.H.3
  • 26
    • 0030734520 scopus 로고    scopus 로고
    • Cooperation of two PEA3/AP1 sites in uPA gene induction by TPA and FGF-2
    • 26. D'Orazio D, Besser D, Marksitzer R et al. Cooperation of two PEA3/AP1 sites in uPA gene induction by TPA and FGF-2. Gene 1997; 201: 179-87.
    • (1997) Gene , vol.201 , pp. 179-187
    • D'Orazio, D.1    Besser, D.2    Marksitzer, R.3
  • 27
    • 0031857536 scopus 로고    scopus 로고
    • UV irradiation induces the murine urokinase-type plasminogen activator gene via the c-Jun N-terminal kinase signaling pathway: Requirement of an AP-1 enhancer element
    • 27. Miralles F, Parra M, Caelles C et al. UV irradiation induces the murine urokinase-type plasminogen activator gene via the c-Jun N-terminal kinase signaling pathway: Requirement of an AP-1 enhancer element. Mol Cell Biol 1998; 18: 4537-47.
    • (1998) Mol Cell Biol , vol.18 , pp. 4537-4547
    • Miralles, F.1    Parra, M.2    Caelles, C.3
  • 28
    • 0032940478 scopus 로고    scopus 로고
    • Transcriptional regulation of urokinase (uPA) gene expression in breast cancer cells: Role of DNA methylation
    • 28. Xing RH, Rabbiani SA. Transcriptional regulation of urokinase (uPA) gene expression in breast cancer cells: role of DNA methylation. Int J Cancer 1999; 81: 443-50.
    • (1999) Int J Cancer , vol.81 , pp. 443-450
    • Xing, R.H.1    Rabbiani, S.A.2
  • 29
    • 0030662713 scopus 로고    scopus 로고
    • Signal transduction in fibroblasts stably transformed by [Val12]Ras. The activities of extracellular-signal-regulated kinase and Jun-N-terminal kinase are only moderately increased, and the activity of the δ-inhibitor of c-Jun is not alleviated
    • 29. Ljungdahl S, Linder S, Sollerbrandt K et al. Signal transduction in fibroblasts stably transformed by [Val12]Ras. The activities of extracellular-signal-regulated kinase and Jun-N-terminal kinase are only moderately increased, and the activity of the δ-inhibitor of c-Jun is not alleviated. Eur J Biochem 1997; 249: 648-56.
    • (1997) Eur J Biochem , vol.249 , pp. 648-656
    • Ljungdahl, S.1    Linder, S.2    Sollerbrandt, K.3
  • 30
    • 0031985094 scopus 로고    scopus 로고
    • Activated Raf-1 causes growth arrest in human small cell lung cancer cells
    • 30. Ravi RK, Weber E, McMahon M et al. Activated Raf-1 causes growth arrest in human small cell lung cancer cells. J Clin Invest 1998; 101: 153-9.
    • (1998) J Clin Invest , vol.101 , pp. 153-159
    • Ravi, R.K.1    Weber, E.2    McMahon, M.3
  • 31
    • 0030660391 scopus 로고    scopus 로고
    • Effects of the inhibition of p38/RK MAP kinase on induction of live fos and jun genes by diverse stimuli
    • 31. Hazzalin CA, Cuenda A, Cano E et al. Effects of the inhibition of p38/RK MAP kinase on induction of live fos and jun genes by diverse stimuli. Oncogene 1997; 15: 2321-31.
    • (1997) Oncogene , vol.15 , pp. 2321-2331
    • Hazzalin, C.A.1    Cuenda, A.2    Cano, E.3
  • 32
    • 0032521642 scopus 로고    scopus 로고
    • The mitogen-activated protein (MAP) kinase cascade can either stimulate or inhibit DNA synthesis in primary cultures of rat hepatocytes depending upon whether its activation is acute/phasic or chronic
    • 32. Tombes RM, Auer KL, Mikkelsen R et al. The mitogen-activated protein (MAP) kinase cascade can either stimulate or inhibit DNA synthesis in primary cultures of rat hepatocytes depending upon whether its activation is acute/phasic or chronic. Biochem J 1998; 330: 1451-60.
    • (1998) Biochem J , vol.330 , pp. 1451-1460
    • Tombes, R.M.1    Auer, K.L.2    Mikkelsen, R.3
  • 33
    • 0031020930 scopus 로고    scopus 로고
    • Cytoskeleton reorganization induces the urokinase-type plasminogen activator gene via the Ras/extracellular signal-regulated kinase (ERK) signaling pathway
    • 33. Irigoyen JP, Besser D, Nagamine Y. Cytoskeleton reorganization induces the urokinase-type plasminogen activator gene via the Ras/extracellular signal-regulated kinase (ERK) signaling pathway. J Biol Chem 1997; 272: 1904-9.
    • (1997) J Biol Chem , vol.272 , pp. 1904-1909
    • Irigoyen, J.P.1    Besser, D.2    Nagamine, Y.3
  • 34
    • 0028872649 scopus 로고
    • Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation
    • 34. Marshall CJ. Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation. Cell 1995; 80: 179-85.
    • (1995) Cell , vol.80 , pp. 179-185
    • Marshall, C.J.1


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