β-Ionone enhances TRAIL-induced apoptosis in hepatocellular carcinoma cells through Sp1-dependent upregulation of DR5 and downregulation of NF-κB activity

Molecular Cancer Therapeutics

Volumn 9, Issue 4, 2010, Pages 833-843

  Kim, Mun Ock ^a   Moon, Dong Oh ^a   Kang, Chang Hee ^a   Kwon, Taeg Kyu ^b   Choi, Yung Hyun ^c   Kim, Gi Young ^a  

^a Jeju National University   (South Korea)

^b Keimyung University   (South Korea)

^c Department of Oriental Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

BETA IONONE; BLOCKING ANTIBODY; CASPASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN DR 5; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR SP1; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; UNCLASSIFIED DRUG; X LINKED INHIBITOR OF APOPTOSIS;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CARCINOMA CELL; CELL VIABILITY; CHROMATIN IMMUNOPRECIPITATION; COLON CARCINOGENESIS; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; GEL MOBILITY SHIFT ASSAY; HUMAN; HUMAN CELL; LEUKEMIA; LIVER CELL CARCINOMA; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; SENSITIZATION; SIGNAL TRANSDUCTION; UPREGULATION;

APOPTOSIS; CARCINOMA, HEPATOCELLULAR; CASPASES; CELL LINE, TUMOR; DOWN-REGULATION; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; LIVER NEOPLASMS; MITOCHONDRIA; NF-KAPPA B; NORISOPRENOIDS; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; RECEPTORS, DEATH DOMAIN; SIGNAL TRANSDUCTION; SP1 TRANSCRIPTION FACTOR; TNF-RELATED APOPTOSIS-INDUCING LIGAND; TRANSCRIPTION, GENETIC; UP-REGULATION;

EID: 77950799171     PISSN: 15357163     EISSN: None     Source Type: Journal    
DOI: 10.1158/1535-7163.MCT-09-0610     Document Type: Article

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