Relative resistance of fresh isolates of melanoma to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis

Clinical Cancer Research

Volumn 7, Issue 11 SUPPL., 2001, Pages

  Nguyen, Tam ^a   Zhang, Xu Dong ^a   Hersey, Peter ^a,b  

^a NEWCASTLE MATER HOSPITAL   (Australia)

^b UNIVERSITY OF NEWCASTLE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS REGULATORY PROTEIN; CARRIER PROTEIN; CFLAR PROTEIN, HUMAN; ENZYME INHIBITOR; FLICE INHIBITORY PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MEMBRANE PROTEIN; MONOCLONAL ANTIBODY; PEPTIDE; PROTEIN BCL 2; SIGNAL PEPTIDE; TNFSF10 PROTEIN, HUMAN; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND;

APOPTOSIS; ARTICLE; BIOSYNTHESIS; CELL CULTURE; CHEMISTRY; CULTURE TECHNIQUE; DOWN REGULATION; DRUG ANTAGONISM; FLOW CYTOMETRY; HUMAN; MELANOMA; METABOLISM; PATHOLOGY; TIME;

ANTIBODIES, MONOCLONAL; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CARRIER PROTEINS; CASP8 AND FADD-LIKE APOPTOSIS REGULATING PROTEIN; CELL CULTURE TECHNIQUES; DOWN-REGULATION; ENZYME INHIBITORS; FLOW CYTOMETRY; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MELANOMA; MEMBRANE GLYCOPROTEINS; NF-KAPPA B; PEPTIDES; PROTO-ONCOGENE PROTEINS C-BCL-2; TIME FACTORS; TNF-RELATED APOPTOSIS-INDUCING LIGAND; TUMOR CELLS, CULTURED; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0035291880     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. Wiley, S. R., Schooley, K., Smolak, P. J., Din, W. S., Huang, C-P., Nicholl, J. K., Sutherland, G. R., Smith, T. D., Rauch, C., Smith, C. A., and Goodwin, R. G. Identification and characterization of a new member of the TNF family that induces apoptosis. Immunity, 3: 673-682, 1995.
2. Pitti, R. M., Marsters, S. A., Ruppert, S., Donahue, C. J., Moore, A., and Ashkenazi, A. Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family. J. Biol. Chem., 271: 12687-12690, 1996.
3. Griffith, T. S., and Lynch, D. H. TRAIL: a molecule with multiple receptors and control mechanisms. Curr. Opin. Immunol., 10: 559-563, 1998.
4. Thomas, W. D., and Hersey, P. TNF-related apoptosis-inducing ligand (TRAIL) induces apoptosis in Fas Ligand-resistant melanoma cells and mediates CD4 T cell killing of target cells. J. Immunol., 161: 2195-2200, 1998.
5. Zhang, X. D., Franco, A., Myers, K., Gray, C., Nguyen, T., and Hersey, P. Relation of TNF-related apoptosis-inducing ligand (TRAIL) receptor and FLICE-inhibitory protein expression to TRAIL-induced apoptosis of melanoma. Cancer Res., 59: 2747-2753, 1999.
6. Griffith, T. S., Chin, W. A., Jackson, G. C., Lynch, D. H., and Kubin, M. Z. Intracellular regulation of TRAIL-induced apoptosis in human melanoma cells. J. Immunol., 161: 2833-2840, 1998.
7. Rieger, J., Naumann, U., Glaser, T., Ashkenazi, A., and Weller, M. APO2 ligand: a novel lethal weapon against malignant glioma? FEBS Lett., 427: 124-128, 1998.
8. Phillips, T. A., Ni, J., Pan, G., Ruben, S. M., Wei, Y-F., Pace, J. L., and Hunt, J. S. TRAIL (Apo-2L) and TRAIL receptors in human placentas: implications for immune privilege. J. Immunol., 162: 6053-6059, 1999.
9. Walczak, H., Miller, R. E., Ariail, K., Gliniak, B., Griffith, T. S., Kubin, M., Chin, W., Jones, J., Woodward, A., Le, T., Smith, C., Smolak, P., Goodwin, R. G., Rauch, C. T., Schuh, J. C. L., and Lynch, D. H. Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo. Nat. Med., 5: 157-163, 1999.
10. Ashkenazi, A., Pai, R. C., Fong, S., Leung, S., Lawrence, D. A., Marsters, S. A., Blackie, C., Chang, L., McMurtrey, A. E., Hebert, A., DeForge, L., Koumenis, I. L., Lewis, D., Harris, L., Bussiere, J., Koeppen, H., Shahrokh, Z., and Schwall, R. H. Safety and antitumor activity of recombinant soluble Apo2 ligand. J. Clin. Investig., 104: 155-162, 1999.
11. Gura, T. How TRAIL kills cancer cells, but not normal cells. Cancer Res., 277: 768, 1997.
12. Thomas, W. D., Zhang, X. D., Franco, A. V., Nguyen, T., and Hersey, P. TRAIL-induced apoptosis of melanoma is associated with changes in mitochondrial membrane potential and perinuclear clustering of mitochondria. J. Immunol., 165: 5612-5620, 2000.
13. Franco, A. V., Zhang, X. D., Van Berkel, E., Thomas, W. D., Nguyen, T., and Hersey, P. The role of NF-κB in TRAIL induced apoptosis of melanoma cells. J. Immunol., in press, 2001.
14. Curry, B. J., Myers, K., and Hersey, P. Polymerase chain reaction detection of melanoma cells in the circulation: relation to clinical stage, surgical treatment, and recurrence from melanoma. J. Clin. Oncol., 16: 1760-1769, 1998.
15. Griffith, T. S., Rauch, C., Smolak, P. J., Waugh, J. Y., Boiani, N., Lynch, D. H., Smith, C. A., Goodwin, R. G., and Kubin, M. Z. Functional analysis of TRAIL receptors using monoclonal antibodies. J. Immunol., 162: 2597-2605, 1999.
16. Palombella, V. J., Rando, O. J., Goldberg, A. L., and Maniatis, T. The ubiquitin-proteasome pathway is required for processing the NF-κB1 precursor protein and the activation of NF-κB. Cell. 78: 773-785, 1994.
17. Jung, T., Schauer, U., Heusser, C., Neumann, C., and Rieger, C. Detection of intracellular cytokines by flow cytometry. J. Immunol. Methods, 159: 197-207, 1993.
18. Sharrow, C. O. Analysis of flow cytornetry data. In: J. E. Coligan, A. M. Kruisbeek, D. H. Margulies, E. M. Shevach, and W. Strober (eds.), Current Protocols in Immunology, Supplement 20.5.2.2. New York: John Wiley and Sons, 1996.
19. Nicoletti, I., Migliorati, G., Pagliacci, M. C., Grignani, F., and Riccardi, C. A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. J. Immunol. Methods, 139: 271-279, 1991.
20. Si, Z., and Hersey, P. Immunohistological examination of the relationship between metastatic potential and expression of adhesion molecules and "selectins" on melanoma cells. Pathology, 26: 6-15, 1994.
21. Zhang, X. D., Franco, A. V., Nguyen, T., and Hersey, P. Differential localization and regulation of death and decoy receptors for TNF-related apoptosis-inducing ligand (TRAIL) in human melanoma cells. J. Immunol., 164: 3961-3970, 2000.
22. Jeremias, I., Kupatt, C., Baumann, B., Herr, I., Wirth, T., and Debatin, K. M. Inhibition of nuclear factor κB activation attenuates apoptosis resistance in lymphoid cells. Blood, 91: 4624-4631, 1998.
23. Zabel, U., Henkel, T., Silva, M. S., and Baeuerle, P. A. Nuclear uptake control of NF-κB by MAD-3, an IκB protein present in the nucleus. EMBO J., 12: 201-211, 1993.
24. Irmler, M., Thome, M., Hahne, M., Schneider, P., Hofmann, K., Steiner, V., Bodmer, J-L., Schroter, M., Burns, K., Mattmann, C., Rimoldi, D., French, L. E., and Tschopp, J. Inhibition of death receptor signals by cellular FLIP. Nature (Lond.), 388: 190-195, 1997.
25. Emery, J. G., McDonnell, P., Burke, M. B., Deen, K. C., Lyn, S., Silverman, C., Dul, E., Appelbaum, E. R., Eichman, C., DiPrinzio, R., Dodds, R. A., James, I. E., Rosenberg, M., Lee, J. C., and Young, P. R. Osteoprotegerin is a receptor for the cytotoxic ligand TRAIL. J. Biol. Chem., 273: 14363-14367, 1998.
26. Sheikh, M. S., Burns, T. F., Huang, Y., Wu, G. S., Amundson, S., Brooks, K. S., Fornace, A. J., Jr., and el-Deiry, W. S. p53-dependent and -independent regulation of the death receptor KILLER/DR5 gene expression in response to genotoxic stress and tumor necrosis factor α. Cancer Res., 58: 1593-1598, 1998.
27. Kayagaki, N., Yamaguchi, N., Nakayama, M., Eto, H., Okumura, K., and Yagita, H. Type I interferons (IFNs) regulate tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) expression on human T cells: a novel mechanism for the antitumor effects of type I IFNs. J. Exp. Med., 189: 1451-1460, 1999.