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Volumn 88, Issue 2, 2010, Pages 219-224

Molecular events in hepatic preneoplasia: A review

Author keywords

Dysplastic foci; Liver stem cells; Microarrays; Progenitor cells

Indexed keywords

AURORA A KINASE; BETA CATENIN; FATTY ACID SYNTHASE; FRIZZLED PROTEIN; GAMMA GLUTAMYLTRANSFERASE; GLUTATHIONE TRANSFERASE; HEAT SHOCK PROTEIN 70; TRANSFORMING GROWTH FACTOR BETA; WNT PROTEIN;

EID: 77950691752     PISSN: 00144800     EISSN: 10960945     Source Type: Journal    
DOI: 10.1016/j.yexmp.2010.01.005     Document Type: Review
Times cited : (11)

References (60)
  • 1
    • 38149004217 scopus 로고    scopus 로고
    • Glypican-3 expression in benign liver tissue with active hepatitis C: implications for the diagnosis of hepatocellular carcinoma
    • Abdul-Al H.M., Makhlou H.R., Wang G., et al. Glypican-3 expression in benign liver tissue with active hepatitis C: implications for the diagnosis of hepatocellular carcinoma. Human Pathol. 2008, 39:209-212.
    • (2008) Human Pathol. , vol.39 , pp. 209-212
    • Abdul-Al, H.M.1    Makhlou, H.R.2    Wang, G.3
  • 2
    • 38649103789 scopus 로고    scopus 로고
    • Wnt/β-catenin signaling mediates oval cell response in rodents
    • Apte U., Thompson M.D., Cui S., et al. Wnt/β-catenin signaling mediates oval cell response in rodents. Hepatology 2008, 47:288-295.
    • (2008) Hepatology , vol.47 , pp. 288-295
    • Apte, U.1    Thompson, M.D.2    Cui, S.3
  • 3
    • 54049142069 scopus 로고    scopus 로고
    • Epigenetic downregulation of the suppressor of cytokine signaling 1 (Socs 1) gene is associated with the STAT3 activation and development of hepatocellular carcinoma induced by methyl-deficiency in rats
    • Bagnyukova T.V., Tryndyak V.P., Muskhelishvilli L., et al. Epigenetic downregulation of the suppressor of cytokine signaling 1 (Socs 1) gene is associated with the STAT3 activation and development of hepatocellular carcinoma induced by methyl-deficiency in rats. Cell Cycl. 2008, 7:3202-3210.
    • (2008) Cell Cycl. , vol.7 , pp. 3202-3210
    • Bagnyukova, T.V.1    Tryndyak, V.P.2    Muskhelishvilli, L.3
  • 4
    • 40949090937 scopus 로고    scopus 로고
    • Epigenetic mechanisms regulate Mallory Denk body formation in the livers of drug-primed mice
    • Bardag-Gorce F., Oliva J., Villegas J., et al. Epigenetic mechanisms regulate Mallory Denk body formation in the livers of drug-primed mice. Exp. Mol. Pathol. 2008, 94:113-121.
    • (2008) Exp. Mol. Pathol. , vol.94 , pp. 113-121
    • Bardag-Gorce, F.1    Oliva, J.2    Villegas, J.3
  • 5
    • 46249095814 scopus 로고    scopus 로고
    • MicroRNA expression profiling: A molecular tool for defining the phenotype of hepatocellular tumors
    • Braconi C., Patel T. MicroRNA expression profiling: A molecular tool for defining the phenotype of hepatocellular tumors. Hepatology 2008, 47:1807-1809.
    • (2008) Hepatology , vol.47 , pp. 1807-1809
    • Braconi, C.1    Patel, T.2
  • 6
    • 84984537259 scopus 로고    scopus 로고
    • P53 gene and Wnt signaling in benign neoplasms: Catenin mutations in hepatic adenoma but not in focal nodular hyperplasia
    • Chen Y.-W., Jeng Y.-M., Yeh S.-H., et al. p53 gene and Wnt signaling in benign neoplasms: Catenin mutations in hepatic adenoma but not in focal nodular hyperplasia. Hepatology 2002, 36:927-935.
    • (2002) Hepatology , vol.36 , pp. 927-935
    • Chen, Y.-W.1    Jeng, Y.-M.2    Yeh, S.-H.3
  • 7
    • 63349098247 scopus 로고    scopus 로고
    • Unique phenotype of hepatocellular cancers with exon-3 mutations in beta-catenin gene
    • Cieply B., Zehg G., Proverbs-Singh T., et al. Unique phenotype of hepatocellular cancers with exon-3 mutations in beta-catenin gene. Hepatology 2009, 49:821-831.
    • (2009) Hepatology , vol.49 , pp. 821-831
    • Cieply, B.1    Zehg, G.2    Proverbs-Singh, T.3
  • 8
    • 0036798694 scopus 로고    scopus 로고
    • Ethanol interactions with a choline-deficient, ethionine-supplemented feeding regime potentiate pre-neoplsatic cellular alterations in rat liver
    • Croager E.J., Smith P.G.J., Yeoh G.C.T. Ethanol interactions with a choline-deficient, ethionine-supplemented feeding regime potentiate pre-neoplsatic cellular alterations in rat liver. Carcinogenesis 2002, 23:1685-1693.
    • (2002) Carcinogenesis , vol.23 , pp. 1685-1693
    • Croager, E.J.1    Smith, P.G.J.2    Yeoh, G.C.T.3
  • 9
    • 61949462471 scopus 로고    scopus 로고
    • East-West pathology agreement on precancerous liver lesions and early hepatocelluar carcinoma
    • Desmet V.J. East-West pathology agreement on precancerous liver lesions and early hepatocelluar carcinoma. Hepatology 2009, 49:355-357.
    • (2009) Hepatology , vol.49 , pp. 355-357
    • Desmet, V.J.1
  • 10
    • 33947396135 scopus 로고    scopus 로고
    • Diagnostic value of HSP70, glypican3 and glutamine synthetase in hepatocellular nodules in cirrhosis
    • Di Tommaso L., Franchi G., Park Y.N., et al. Diagnostic value of HSP70, glypican3 and glutamine synthetase in hepatocellular nodules in cirrhosis. Hepatology 2007, 45:725-734.
    • (2007) Hepatology , vol.45 , pp. 725-734
    • Di Tommaso, L.1    Franchi, G.2    Park, Y.N.3
  • 11
    • 12344261004 scopus 로고    scopus 로고
    • Overexpression of fatty acid synthase in chemically and hormonally induced hepatocarcinogenesis of the rat
    • Evert M., Schneider-Stock R., Dombrowski F. Overexpression of fatty acid synthase in chemically and hormonally induced hepatocarcinogenesis of the rat. Lab. Invest. 2005, 85:99-108.
    • (2005) Lab. Invest. , vol.85 , pp. 99-108
    • Evert, M.1    Schneider-Stock, R.2    Dombrowski, F.3
  • 12
    • 38949173151 scopus 로고    scopus 로고
    • Development of glutathione S-transferase-P-negative foci accompanying nuclear factor-erythroid 2-related factor 2 expression during early state of rat hepatocarcinogenesis
    • Fan Y., Shimizu T., Yamada T., et al. Development of glutathione S-transferase-P-negative foci accompanying nuclear factor-erythroid 2-related factor 2 expression during early state of rat hepatocarcinogenesis. Cancer Sci. 2008, 99:497-501.
    • (2008) Cancer Sci. , vol.99 , pp. 497-501
    • Fan, Y.1    Shimizu, T.2    Yamada, T.3
  • 13
    • 0042440603 scopus 로고    scopus 로고
    • Differential impact of telemere dysfunction on initiation and progression of hepatocellular carcinoma
    • Farazi P.A., Glickman J., Jiang S., et al. Differential impact of telemere dysfunction on initiation and progression of hepatocellular carcinoma. Cancer Res. 2003, 63:5021-5027.
    • (2003) Cancer Res. , vol.63 , pp. 5021-5027
    • Farazi, P.A.1    Glickman, J.2    Jiang, S.3
  • 14
    • 0025370064 scopus 로고
    • Clonal adaptation during carcinogenesis
    • Farber E. Clonal adaptation during carcinogenesis. Biochem. Pharmacol. 1990, 39:1837-1846.
    • (1990) Biochem. Pharmacol. , vol.39 , pp. 1837-1846
    • Farber, E.1
  • 15
    • 67650224486 scopus 로고    scopus 로고
    • Genetic and epigenetic control of molecular alternations in hepatocellular carcinoma
    • Feo F., Frau M., Tomasi M.L., et al. Genetic and epigenetic control of molecular alternations in hepatocellular carcinoma. Exp. Biol. Med. 2009, 234:726-736.
    • (2009) Exp. Biol. Med. , vol.234 , pp. 726-736
    • Feo, F.1    Frau, M.2    Tomasi, M.L.3
  • 16
    • 54849375900 scopus 로고    scopus 로고
    • One year chronic toxicity of madden color in F344 rats. Induction of preneoplastic/neoplastic lesions in the kidney and liver
    • Inoue K., Shibutani M., Masutomi N., et al. One year chronic toxicity of madden color in F344 rats. Induction of preneoplastic/neoplastic lesions in the kidney and liver. Food Chem. Toxicol. 2008, 46:3303-3310.
    • (2008) Food Chem. Toxicol. , vol.46 , pp. 3303-3310
    • Inoue, K.1    Shibutani, M.2    Masutomi, N.3
  • 17
    • 61949171989 scopus 로고    scopus 로고
    • Pathology diagnosis of early hepatocellular carcinoma: A report of the international concensus group for hepatocellular neoplasia
    • International Consensus Group for Hepatocellular Neoplasms
    • Pathology diagnosis of early hepatocellular carcinoma: A report of the international concensus group for hepatocellular neoplasia. Hepatology 2009, 49:658-664. International Consensus Group for Hepatocellular Neoplasms.
    • (2009) Hepatology , vol.49 , pp. 658-664
  • 19
    • 20344399151 scopus 로고    scopus 로고
    • Early hepatocellular carcinoma and dysplasia nodules
    • Kojiro M., Roskams T. Early hepatocellular carcinoma and dysplasia nodules. Semin. Liver Dis. 2005, 25:133-142.
    • (2005) Semin. Liver Dis. , vol.25 , pp. 133-142
    • Kojiro, M.1    Roskams, T.2
  • 20
    • 0033873765 scopus 로고    scopus 로고
    • Differentiatial growth: from carcinogenesis to liver repopulation
    • Laconi E. Differentiatial growth: from carcinogenesis to liver repopulation. Am. J. Pathol. 2000, 156:389-392.
    • (2000) Am. J. Pathol. , vol.156 , pp. 389-392
    • Laconi, E.1
  • 21
    • 0141648473 scopus 로고    scopus 로고
    • Aberrant CpG island hypermethylation along multistep hepatocarcinogenesis
    • Lee S., Lee H.J., Kim J.-H., et al. Aberrant CpG island hypermethylation along multistep hepatocarcinogenesis. Am. J. Pathol. 2003, 163:1371-1378.
    • (2003) Am. J. Pathol. , vol.163 , pp. 1371-1378
    • Lee, S.1    Lee, H.J.2    Kim, J.-H.3
  • 22
    • 0038192327 scopus 로고    scopus 로고
    • Expression of the FAT10 gene is highly upregulated in hepatocellular carcinoma and other gastrointestinal and gynecological cancers
    • Lee C.G., Ren J., Cheong I.S., et al. Expression of the FAT10 gene is highly upregulated in hepatocellular carcinoma and other gastrointestinal and gynecological cancers. Oncogene 2003, 22:2592-2603.
    • (2003) Oncogene , vol.22 , pp. 2592-2603
    • Lee, C.G.1    Ren, J.2    Cheong, I.S.3
  • 23
    • 39549103864 scopus 로고    scopus 로고
    • S-adenosylmethionine prevents Mallory Denk body formation in drug-primed mice by inhibiting epigenetic memory
    • Li J., Bardag-Gorce F., Dedes J., et al. S-adenosylmethionine prevents Mallory Denk body formation in drug-primed mice by inhibiting epigenetic memory. Hepatology 2008, 47:613-624.
    • (2008) Hepatology , vol.47 , pp. 613-624
    • Li, J.1    Bardag-Gorce, F.2    Dedes, J.3
  • 24
    • 33750798339 scopus 로고    scopus 로고
    • Hepatic progenitor cells in human liver tumor development
    • Libbrecht L. Hepatic progenitor cells in human liver tumor development. World J. Gastroenterol. 2006, 12:6261-6265.
    • (2006) World J. Gastroenterol. , vol.12 , pp. 6261-6265
    • Libbrecht, L.1
  • 25
    • 33845790499 scopus 로고    scopus 로고
    • A molecular signature to descriminate dysplastic nodules from early hepatocellular carcinoma in HCV cirrhosis
    • Llovet J.M., Chen Y., Wurmbach E., et al. A molecular signature to descriminate dysplastic nodules from early hepatocellular carcinoma in HCV cirrhosis. Gastroenterology 2006, 131:1758-1767.
    • (2006) Gastroenterology , vol.131 , pp. 1758-1767
    • Llovet, J.M.1    Chen, Y.2    Wurmbach, E.3
  • 26
    • 68949180034 scopus 로고    scopus 로고
    • S-adenosylmethionine in the chemoprevention and treatment of hepatocellular carcinoma in a rat model
    • Lu S.C., Ramani K., Ou X., et al. S-adenosylmethionine in the chemoprevention and treatment of hepatocellular carcinoma in a rat model. Hepatology 2009, 50:462-471.
    • (2009) Hepatology , vol.50 , pp. 462-471
    • Lu, S.C.1    Ramani, K.2    Ou, X.3
  • 27
    • 53649108526 scopus 로고    scopus 로고
    • Proinflammatory cytokines cause FAT10 upregulation in cancers of the liver and colon
    • Lukasiak S., Schiller C., Oehischlaeger P., et al. Proinflammatory cytokines cause FAT10 upregulation in cancers of the liver and colon. Oncogene 2008, 27:6068-6074.
    • (2008) Oncogene , vol.27 , pp. 6068-6074
    • Lukasiak, S.1    Schiller, C.2    Oehischlaeger, P.3
  • 28
    • 60849102149 scopus 로고    scopus 로고
    • Toll-like receptor 4 mediates synergism between alcohol and HCV in hepatic oncogenesis involving stem cell markers Namog
    • Machida K., Tsukamoto H., Mkrtch H., et al. Toll-like receptor 4 mediates synergism between alcohol and HCV in hepatic oncogenesis involving stem cell markers Namog. PNAS 2009, 106:1548-1553.
    • (2009) PNAS , vol.106 , pp. 1548-1553
    • Machida, K.1    Tsukamoto, H.2    Mkrtch, H.3
  • 29
    • 42449106157 scopus 로고    scopus 로고
    • Molecular pathogenesis of hepatocellular carcinoma
    • Metodieva S.N. Molecular pathogenesis of hepatocellular carcinoma. Balkan J. Med. Genet. 2008, 10:15-22.
    • (2008) Balkan J. Med. Genet. , vol.10 , pp. 15-22
    • Metodieva, S.N.1
  • 30
    • 58949088366 scopus 로고    scopus 로고
    • Liver stem cells and hepatocellular carcinoma
    • Mishra L., Banker T., Murray J., et al. Liver stem cells and hepatocellular carcinoma. Hepatology 2009, 49:318-329.
    • (2009) Hepatology , vol.49 , pp. 318-329
    • Mishra, L.1    Banker, T.2    Murray, J.3
  • 31
    • 33645222607 scopus 로고    scopus 로고
    • Hepatic adenomas: presumed innocent until proven to be beta-catenin mutate
    • Monga S.P.S. Hepatic adenomas: presumed innocent until proven to be beta-catenin mutate. Hepatology 2006, 43:401-404.
    • (2006) Hepatology , vol.43 , pp. 401-404
    • Monga, S.P.S.1
  • 32
    • 62849106337 scopus 로고    scopus 로고
    • β-Catenin histochromatin: regulation of Wnt target gene activation
    • Mosimann C., Hausmann G., Basier K. β-Catenin histochromatin: regulation of Wnt target gene activation. Nat. Rev. Mol. Cell. Biol. 2009, 10:276-286.
    • (2009) Nat. Rev. Mol. Cell. Biol. , vol.10 , pp. 276-286
    • Mosimann, C.1    Hausmann, G.2    Basier, K.3
  • 33
    • 48549106666 scopus 로고    scopus 로고
    • Evidence of a threshold for 2-amino-3, 8-dimethylimidazo-[4, 5-f] quinoxaline liver carcinogenicity in F344/DuCrj rats
    • Murrai T., Mori S., Kang J.S., et al. Evidence of a threshold for 2-amino-3, 8-dimethylimidazo-[4, 5-f] quinoxaline liver carcinogenicity in F344/DuCrj rats. Toxicol. Pathol. 2008, 36:472-477.
    • (2008) Toxicol. Pathol. , vol.36 , pp. 472-477
    • Murrai, T.1    Mori, S.2    Kang, J.S.3
  • 34
    • 0032444729 scopus 로고    scopus 로고
    • Pathogenesis of Mallory body formation: Studies using the drug-primed mouse model
    • Nagao Y., Yuan Q.-X., Wan Y-J Y., et al. Pathogenesis of Mallory body formation: Studies using the drug-primed mouse model. Hepatol. Res. 1998, 13:42-54.
    • (1998) Hepatol. Res. , vol.13 , pp. 42-54
    • Nagao, Y.1    Yuan, Q.-X.2    Wan Y-J, Y.3
  • 35
    • 0032816783 scopus 로고    scopus 로고
    • Mouse model of hepatocellular hyperplastic nodule formation characterization of mRNA expression
    • Nagao Y., Wan Y-J Y., Yuan Q.X., et al. Mouse model of hepatocellular hyperplastic nodule formation characterization of mRNA expression. Hepatol. Res. 1999, 15:110-123.
    • (1999) Hepatol. Res. , vol.15 , pp. 110-123
    • Nagao, Y.1    Wan Y-J, Y.2    Yuan, Q.X.3
  • 36
    • 25844461787 scopus 로고    scopus 로고
    • Molecular changes from dysplastic nodule to hepatocellular carcinoma through gene expression profiling
    • Nam S.W., Park J.Y., Ramasamy A., et al. Molecular changes from dysplastic nodule to hepatocellular carcinoma through gene expression profiling. Hepatology 2005, 42:809-818.
    • (2005) Hepatology , vol.42 , pp. 809-818
    • Nam, S.W.1    Park, J.Y.2    Ramasamy, A.3
  • 37
    • 33644539500 scopus 로고    scopus 로고
    • Mallory body forming cells express the preneoplastic hepatocyte phenotype
    • Nan L., Bardag-Gorce F., Wu Y., et al. Mallory body forming cells express the preneoplastic hepatocyte phenotype. Exp. Mol. Pathol. 2006, 80:109-118.
    • (2006) Exp. Mol. Pathol. , vol.80 , pp. 109-118
    • Nan, L.1    Bardag-Gorce, F.2    Wu, Y.3
  • 38
    • 50649120637 scopus 로고    scopus 로고
    • Possible involvement of oxidative stress in fenofibrate-induced hepatocarcinogenesis in rats
    • Nishimura J., Dewa Y., Okamura T., et al. Possible involvement of oxidative stress in fenofibrate-induced hepatocarcinogenesis in rats. Arch. Toxicol. 2008, 82:641-654.
    • (2008) Arch. Toxicol. , vol.82 , pp. 641-654
    • Nishimura, J.1    Dewa, Y.2    Okamura, T.3
  • 39
    • 40949091503 scopus 로고    scopus 로고
    • FAT10 is an epigenetic marker for liver preneoplasia in a drug-primed mouse model of tumorigenesis
    • Oliva J., Bardag-Gorce F., French B.A., et al. FAT10 is an epigenetic marker for liver preneoplasia in a drug-primed mouse model of tumorigenesis. Exp. Mol. Pathol. 2008, 84:102-112.
    • (2008) Exp. Mol. Pathol. , vol.84 , pp. 102-112
    • Oliva, J.1    Bardag-Gorce, F.2    French, B.A.3
  • 40
    • 63149110033 scopus 로고    scopus 로고
    • Betaine prevents Mallory-Denk body formation in drug-primed mice by epigenetic mechanisms
    • Oliva J., Bardag-Gorce F., Li J., et al. Betaine prevents Mallory-Denk body formation in drug-primed mice by epigenetic mechanisms. Exp. Mol. Pathol. 2009, 86:77-86.
    • (2009) Exp. Mol. Pathol. , vol.86 , pp. 77-86
    • Oliva, J.1    Bardag-Gorce, F.2    Li, J.3
  • 41
    • 0036024252 scopus 로고    scopus 로고
    • Chemoprotection of hepatocarcinogenesis: S-adenosyl-L-methionine
    • Pascale R.M., Simile M.M., DeMiglio M.R., et al. Chemoprotection of hepatocarcinogenesis: S-adenosyl-L-methionine. Alcohol 2002, 27:193-198.
    • (2002) Alcohol , vol.27 , pp. 193-198
    • Pascale, R.M.1    Simile, M.M.2    DeMiglio, M.R.3
  • 42
    • 65449134288 scopus 로고    scopus 로고
    • Thyroid hormone receptor ligands induce regression of rat preneoplastic liver lesions causing their reversion to a differentiated phenotype
    • Perra A., Kowalik M.A., Pibiri M., et al. Thyroid hormone receptor ligands induce regression of rat preneoplastic liver lesions causing their reversion to a differentiated phenotype. Hepatology 2009, 49:1287-1296.
    • (2009) Hepatology , vol.49 , pp. 1287-1296
    • Perra, A.1    Kowalik, M.A.2    Pibiri, M.3
  • 43
    • 0034884735 scopus 로고    scopus 로고
    • Hepatic "stem" cells: coming full circle
    • Petersen B.E. Hepatic "stem" cells: coming full circle. Blood Cells Mol. Dis. 2001, 27:590-600.
    • (2001) Blood Cells Mol. Dis. , vol.27 , pp. 590-600
    • Petersen, B.E.1
  • 44
    • 33744951950 scopus 로고    scopus 로고
    • FAT10 plays a role in the regulation of chromosomal stability
    • Ren J., Kan A., Leong S.H., et al. FAT10 plays a role in the regulation of chromosomal stability. J. Biol. Chem. 2006, 281:11413-11421.
    • (2006) J. Biol. Chem. , vol.281 , pp. 11413-11421
    • Ren, J.1    Kan, A.2    Leong, S.H.3
  • 45
  • 46
    • 33745435636 scopus 로고    scopus 로고
    • Preneoplastic liver cell foci induced by thioacetamide toxicity in drug primed liver
    • Roomi M.W., Gaal K., Yuan Q.X., et al. Preneoplastic liver cell foci induced by thioacetamide toxicity in drug primed liver. Exp. Mol. Pathol. 2006, 81:8-14.
    • (2006) Exp. Mol. Pathol. , vol.81 , pp. 8-14
    • Roomi, M.W.1    Gaal, K.2    Yuan, Q.X.3
  • 47
    • 58849087179 scopus 로고    scopus 로고
    • Early HCC: Diagnosis and molecular markers
    • Sakamoto M. Early HCC: Diagnosis and molecular markers. J. Gastroenterol. 2009, 44(Suppl XIX):108-111.
    • (2009) J. Gastroenterol. , vol.44 , Issue.19 SUPPL. , pp. 108-111
    • Sakamoto, M.1
  • 48
    • 52449102990 scopus 로고    scopus 로고
    • Bile duct-bound growth of precursor cells of preneoplastic foci inducible in the initiation stage of rat chemical hepatocarcinogenesis by Z-acetylminofluorene
    • Satoh K., Yamakawa D., Sugio H., et al. Bile duct-bound growth of precursor cells of preneoplastic foci inducible in the initiation stage of rat chemical hepatocarcinogenesis by Z-acetylminofluorene. Jpn. J. Clin. Oncol. 2008, 38:604-610.
    • (2008) Jpn. J. Clin. Oncol. , vol.38 , pp. 604-610
    • Satoh, K.1    Yamakawa, D.2    Sugio, H.3
  • 49
    • 49649128638 scopus 로고    scopus 로고
    • Epigenetic drivers and genetic passengers on the road to cancer
    • Sawan C., Vaissiere T., Murr R., et al. Epigenetic drivers and genetic passengers on the road to cancer. Mutat. Res. 2008, 642:1-13.
    • (2008) Mutat. Res. , vol.642 , pp. 1-13
    • Sawan, C.1    Vaissiere, T.2    Murr, R.3
  • 50
    • 43849086124 scopus 로고    scopus 로고
    • Tomato oleoresin inhibits DNA damage but not diethylnitrosamine-induced rat hepatocarcinogenesis
    • Scolastici C., Lopes G.A.D., Barbisan L.F., et al. Tomato oleoresin inhibits DNA damage but not diethylnitrosamine-induced rat hepatocarcinogenesis. Exp. Toxicol. Pathol. 2008, 60:59-68.
    • (2008) Exp. Toxicol. Pathol. , vol.60 , pp. 59-68
    • Scolastici, C.1    Lopes, G.A.D.2    Barbisan, L.F.3
  • 51
    • 46449130337 scopus 로고    scopus 로고
    • Alpha-fetoprotein, stem cells and cancer: How study of the production of alpha-fetoprotein during chemical hepatocarcinogenesis led to reaffirmation of the stem cell theory of cancer
    • Sell S. Alpha-fetoprotein, stem cells and cancer: How study of the production of alpha-fetoprotein during chemical hepatocarcinogenesis led to reaffirmation of the stem cell theory of cancer. Tumor Biol. Biol. 2008, 29:161-180.
    • (2008) Tumor Biol. Biol. , vol.29 , pp. 161-180
    • Sell, S.1
  • 52
    • 0017692938 scopus 로고
    • Rapid emergence of carcinogen-induced hyperplastic lesions in a new model for the sequential analysis of liver carcinogenesis
    • Solt D.B., Medline A., Farber E. Rapid emergence of carcinogen-induced hyperplastic lesions in a new model for the sequential analysis of liver carcinogenesis. Am. J. Pathol. 1977, 88:595-618.
    • (1977) Am. J. Pathol. , vol.88 , pp. 595-618
    • Solt, D.B.1    Medline, A.2    Farber, E.3
  • 53
    • 7244242265 scopus 로고    scopus 로고
    • α2-macroglobulin: A novel cytochemical marker characterizing preneoplastic and neoplastic rat liver lesions negative for hitherto established cytochemical markers
    • Sukata T., Uwagawa S., Ozaki K., et al. α2-macroglobulin: A novel cytochemical marker characterizing preneoplastic and neoplastic rat liver lesions negative for hitherto established cytochemical markers. Am. J. Pathol. 2004, 165:1479-1488.
    • (2004) Am. J. Pathol. , vol.165 , pp. 1479-1488
    • Sukata, T.1    Uwagawa, S.2    Ozaki, K.3
  • 54
    • 61949483613 scopus 로고    scopus 로고
    • Recruitment of host progenitor cells in rat liver transplants
    • Sun S., Zhang X., Locke J.E., et al. Recruitment of host progenitor cells in rat liver transplants. Hepatology 2009, 49:587-597.
    • (2009) Hepatology , vol.49 , pp. 587-597
    • Sun, S.1    Zhang, X.2    Locke, J.E.3
  • 55
    • 0021024082 scopus 로고
    • Mallory body formation is linked to gamma glutamyl transferase induction in hepatocytes of griseofulvin-fed mice
    • Tazawa J., Irie T., French S.W. Mallory body formation is linked to gamma glutamyl transferase induction in hepatocytes of griseofulvin-fed mice. Hepatology 1983, 3:989-1001.
    • (1983) Hepatology , vol.3 , pp. 989-1001
    • Tazawa, J.1    Irie, T.2    French, S.W.3
  • 56
    • 46249134069 scopus 로고    scopus 로고
    • Defective DNA strand break repair causes chromosomal instability and accelerates liver carcinogenesis in mice
    • Teoh N.C., Dan Y.Y., Swisshelm K., et al. Defective DNA strand break repair causes chromosomal instability and accelerates liver carcinogenesis in mice. Hepatology 2008, 47:2078-2088.
    • (2008) Hepatology , vol.47 , pp. 2078-2088
    • Teoh, N.C.1    Dan, Y.Y.2    Swisshelm, K.3
  • 57
    • 33644509480 scopus 로고    scopus 로고
    • Hematopoietic cells as hepatocyte stem cells: A critical review of the evidence
    • Thorgeirson S.S., Grisham J.W. Hematopoietic cells as hepatocyte stem cells: A critical review of the evidence. Hepatology 2006, 43:2-8.
    • (2006) Hepatology , vol.43 , pp. 2-8
    • Thorgeirson, S.S.1    Grisham, J.W.2
  • 58
    • 33847069207 scopus 로고    scopus 로고
    • Genomics and signaling pathway in hepatocellular carcinoma
    • Villanueva A., Nowell P., Chang D.Y., et al. Genomics and signaling pathway in hepatocellular carcinoma. Semin. Liver Dis. 2007, 27:55-76.
    • (2007) Semin. Liver Dis. , vol.27 , pp. 55-76
    • Villanueva, A.1    Nowell, P.2    Chang, D.Y.3
  • 59
    • 34247549347 scopus 로고    scopus 로고
    • Genome-wide molecular profiles of HCV-induced dysplasia and hepatocellular carcinoma
    • Wurmbach E., Chen Y.-B., Knitrov G., et al. Genome-wide molecular profiles of HCV-induced dysplasia and hepatocellular carcinoma. Hepatology 2007, 45:938-947.
    • (2007) Hepatology , vol.45 , pp. 938-947
    • Wurmbach, E.1    Chen, Y.-B.2    Knitrov, G.3
  • 60
    • 0037327198 scopus 로고    scopus 로고
    • Small epithelial cells in human liver cirrhosis exhibit features of hepatic stem cells in human liver cirrhosis exhibit features of hepatic stem-like cells: immunohistochemical, electron microscopic and immunoelectron microscopic findings
    • Xiao J.-C., Ruck P., Adam A., et al. Small epithelial cells in human liver cirrhosis exhibit features of hepatic stem cells in human liver cirrhosis exhibit features of hepatic stem-like cells: immunohistochemical, electron microscopic and immunoelectron microscopic findings. Histopathology 2003, 42:141-149.
    • (2003) Histopathology , vol.42 , pp. 141-149
    • Xiao, J.-C.1    Ruck, P.2    Adam, A.3


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