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Volumn 29, Issue 12, 2008, Pages 2252-2258

Artemisinin selectively decreases functional levels of estrogen receptor-alpha and ablates estrogen-induced proliferation in human breast cancer cells

Author keywords

[No Author keywords available]

Indexed keywords

1,3,5 TRIS(4 HYDROXYPHENYL) 4 PROPYLPYRAZOLE; ARTEMISININ; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; FULVESTRANT; PROGESTERONE RECEPTOR;

EID: 57349179869     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgn214     Document Type: Article
Times cited : (50)

References (37)
  • 1
    • 34548305781 scopus 로고    scopus 로고
    • Breast cancer: Trends, risks, treatments, and effects
    • Draper,L. (2006) Breast cancer: Trends, risks, treatments, and effects. AAOHN J., 54, 445-453.
    • (2006) AAOHN J , vol.54 , pp. 445-453
    • Draper, L.1
  • 2
    • 1542344018 scopus 로고    scopus 로고
    • Estradiol and selective estrogen receptor modulators differentially regulate target genes with estrogen receptors alpha and beta
    • Kian Tee,M. et al. (2004) Estradiol and selective estrogen receptor modulators differentially regulate target genes with estrogen receptors alpha and beta. Mol. Biol. Cell, 15, 1262-1272.
    • (2004) Mol. Biol. Cell , vol.15 , pp. 1262-1272
    • Kian Tee, M.1
  • 3
    • 0031240327 scopus 로고    scopus 로고
    • Mammary gland development and tumorigenesis in estrogen receptor knockout mice
    • Bocchinfuso,W.P. et al. (1997) Mammary gland development and tumorigenesis in estrogen receptor knockout mice, J. Mammary Gland Biol. Neoplasia, 2, 323-334.
    • (1997) J. Mammary Gland Biol. Neoplasia , vol.2 , pp. 323-334
    • Bocchinfuso, W.P.1
  • 4
    • 0034463181 scopus 로고    scopus 로고
    • Induction of mammary gland development in estrogen receptor-alpha knockout mice
    • Bocchinfuso,WP. et al. (2000) Induction of mammary gland development in estrogen receptor-alpha knockout mice. Endocrinology 141, 2982-2994.
    • (2000) Endocrinology , vol.141 , pp. 2982-2994
    • Bocchinfuso, W.P.1
  • 5
    • 33751530274 scopus 로고    scopus 로고
    • Steroid receptors and their role in the biology and control of breast cancer growth
    • Cordera,F. et al. (2006) Steroid receptors and their role in the biology and control of breast cancer growth. Semin. Oncol., 33 631-641.
    • (2006) Semin. Oncol , vol.33 , pp. 631-641
    • Cordera, F.1
  • 6
    • 0345382876 scopus 로고    scopus 로고
    • Involvement of estrogen receptor beta in terminal differentiation of mammary gland epithelium
    • Forster,C. et al. (2002) Involvement of estrogen receptor beta in terminal differentiation of mammary gland epithelium. Proc. Natl Acad. Sci. USA, 99, 15578-15583.
    • (2002) Proc. Natl Acad. Sci. USA , vol.99 , pp. 15578-15583
    • Forster, C.1
  • 7
    • 13444272959 scopus 로고    scopus 로고
    • Deregulated estrogen receptor alpha expression in mammary epithelial cells of transgenic mice results in the development of ductal carcinoma in situ
    • Frech,M.S. et al. (2005) Deregulated estrogen receptor alpha expression in mammary epithelial cells of transgenic mice results in the development of ductal carcinoma in situ. Cancer Res., 65, 681-685.
    • (2005) Cancer Res , vol.65 , pp. 681-685
    • Frech, M.S.1
  • 8
    • 0037093223 scopus 로고    scopus 로고
    • Lack of ductal development in the absence of functional estrogen receptor alpha delays mammary tumor formation induced by trarnsgenic expression of ErbB2/neu
    • Hewitt,S.C. et al. (2002) Lack of ductal development in the absence of functional estrogen receptor alpha delays mammary tumor formation induced by trarnsgenic expression of ErbB2/neu. Cancer Res. 62, 2798-2805.
    • (2002) Cancer Res , vol.62 , pp. 2798-2805
    • Hewitt, S.C.1
  • 9
    • 0034868904 scopus 로고    scopus 로고
    • ER beta inhibits proliferation and invasion of breast cancer cells
    • Lazennec,G. et al. (2001) ER beta inhibits proliferation and invasion of breast cancer cells. Endocrinology, 142, 4120-4130.
    • (2001) Endocrinology , vol.142 , pp. 4120-4130
    • Lazennec, G.1
  • 10
    • 0034990627 scopus 로고    scopus 로고
    • Quantitative analysis of estrogen receptor proteins in rat mammary gland
    • Saji,S. et al. (2001) Quantitative analysis of estrogen receptor proteins in rat mammary gland. Endocrinology, 142, 3177-3186.
    • (2001) Endocrinology , vol.142 , pp. 3177-3186
    • Saji, S.1
  • 11
    • 0036127795 scopus 로고    scopus 로고
    • Cellular expression of estrogen and progesterone receptors in mammary glands: Regulation by hormones, development and aging
    • Shyamala,G. et al. (2002) Cellular expression of estrogen and progesterone receptors in mammary glands: Regulation by hormones, development and aging. J. Steroid Biochem. Mol. Biol., 80, 137-148.
    • (2002) J. Steroid Biochem. Mol. Biol , vol.80 , pp. 137-148
    • Shyamala, G.1
  • 12
    • 1242300083 scopus 로고    scopus 로고
    • Estrogen receptor beta inhibits 17beta-estradiol-stimulated proliferation of the breast cancer cell line T47D
    • Strom,A. et al. (2004) Estrogen receptor beta inhibits 17beta-estradiol-stimulated proliferation of the breast cancer cell line T47D. Proc. Natl Acad. Sci. USA, 101, 1566-1571.
    • (2004) Proc. Natl Acad. Sci. USA , vol.101 , pp. 1566-1571
    • Strom, A.1
  • 13
    • 33751544458 scopus 로고    scopus 로고
    • Indole-3-carbinol selectively uncouples expression and activity of estrogen receptor subtypes in human breast cancer cells
    • Sundar,S.N. et al. (2006) Indole-3-carbinol selectively uncouples expression and activity of estrogen receptor subtypes in human breast cancer cells. Mol. Endocrinol., 20, 3070-3082.
    • (2006) Mol. Endocrinol , vol.20 , pp. 3070-3082
    • Sundar, S.N.1
  • 14
    • 1642535535 scopus 로고    scopus 로고
    • Estrogen receptor beta inhibits human breast cancer cell proliferation and tumor formation by causing a G2 cell cycle arrest
    • Paruthiyil,S. et al. (2004) Estrogen receptor beta inhibits human breast cancer cell proliferation and tumor formation by causing a G2 cell cycle arrest. Cancer Res., 64, 423-428.
    • (2004) Cancer Res , vol.64 , pp. 423-428
    • Paruthiyil, S.1
  • 15
    • 33646129245 scopus 로고    scopus 로고
    • Estrogen receptors as therapeutic targets in breast cancer
    • Ariazi,E.A. et al. (2006) Estrogen receptors as therapeutic targets in breast cancer. Curr. Top. Med. Chem., 6, 181-202.
    • (2006) Curr. Top. Med. Chem , vol.6 , pp. 181-202
    • Ariazi, E.A.1
  • 16
    • 0032822027 scopus 로고    scopus 로고
    • Chemoprevention of breast cancer
    • Osborne,M.P. (1999) Chemoprevention of breast cancer. Surg. Clin. North Am., 79, 1207-1221.
    • (1999) Surg. Clin. North Am , vol.79 , pp. 1207-1221
    • Osborne, M.P.1
  • 17
    • 25844509287 scopus 로고    scopus 로고
    • Analysis of estrogen agonism and antagonism of tamoxifen, raloxifene, and ICI182780 in endometrial cancer cells: A putative role for the epidermal growth factor receptor ligand amphiregutin
    • Gielen,S.C. et al. (2005) Analysis of estrogen agonism and antagonism of tamoxifen, raloxifene, and ICI182780 in endometrial cancer cells: A putative role for the epidermal growth factor receptor ligand amphiregutin. J. Soc. Gynecol. Investig., 12, e55-e67.
    • (2005) J. Soc. Gynecol. Investig , vol.12
    • Gielen, S.C.1
  • 18
    • 0043270405 scopus 로고    scopus 로고
    • Artemisinin and heme
    • author reply 2712-2713
    • Meshnick,S.R. (2003) Artemisinin and heme. Antimicrob. Agents Chemother., 47, 2712; author reply 2712-2713.
    • (2003) Antimicrob. Agents Chemother , vol.47 , pp. 2712
    • Meshnick, S.R.1
  • 19
    • 33646461526 scopus 로고    scopus 로고
    • Second generation, orally active, antimalarial, artemisinin-derived trioxane dimers with high stability, efficacy, and anti-cancer activity
    • Paik,I.H. et al. (2006) Second generation, orally active, antimalarial, artemisinin-derived trioxane dimers with high stability, efficacy, and anti-cancer activity. J. Med. Chem., 49, 2731-2734.
    • (2006) J. Med. Chem , vol.49 , pp. 2731-2734
    • Paik, I.H.1
  • 20
    • 8844258698 scopus 로고    scopus 로고
    • Inhibition of angiogenesis in vivo and growth of Kaposi's sarcoma xenograft tumors by the anti-malarial artesunate
    • Dell'Eva,R. et al. (2004) Inhibition of angiogenesis in vivo and growth of Kaposi's sarcoma xenograft tumors by the anti-malarial artesunate. Biochem. Pharmacol., 68, 2359-2366.
    • (2004) Biochem. Pharmacol , vol.68 , pp. 2359-2366
    • Dell'Eva, R.1
  • 21
    • 4444383530 scopus 로고    scopus 로고
    • Enhancement of cytotoxicity of artemisinins toward cancer cells by ferrous iron
    • Efferth,T. et al. (2004) Enhancement of cytotoxicity of artemisinins toward cancer cells by ferrous iron. Free Radic. Biol. Med., 37, 998-1009.
    • (2004) Free Radic. Biol. Med , vol.37 , pp. 998-1009
    • Efferth, T.1
  • 22
    • 34247255872 scopus 로고    scopus 로고
    • Effects of artemisinin and its derivatives on growth inhibition and apoptosis of oral cancer cells
    • Nam,W. et al. (2007) Effects of artemisinin and its derivatives on growth inhibition and apoptosis of oral cancer cells. Head Neck, 29, 335-340.
    • (2007) Head Neck , vol.29 , pp. 335-340
    • Nam, W.1
  • 23
    • 0030893778 scopus 로고    scopus 로고
    • Artemisinin enhances heme-catalysed oxidation of lipid membranes
    • Berman,RA. et al. (1997) Artemisinin enhances heme-catalysed oxidation of lipid membranes. Free Radic. Biol. Med., 22, 1283-1288.
    • (1997) Free Radic. Biol. Med , vol.22 , pp. 1283-1288
    • Berman, R.A.1
  • 24
    • 0035315838 scopus 로고    scopus 로고
    • The anti-malarial artesunate is also active against cancer
    • Efferth,T. et al. (2001) The anti-malarial artesunate is also active against cancer. Int. J. Oncol., 18, 767-773.
    • (2001) Int. J. Oncol , vol.18 , pp. 767-773
    • Efferth, T.1
  • 25
    • 28844439369 scopus 로고    scopus 로고
    • Oral artemisinin prevents and delays the development of 7,12-dimethylbenz(a)anthracene (DMBA)-induced breast cancer in the rat
    • Lai,H. et al. (2006) Oral artemisinin prevents and delays the development of 7,12-dimethylbenz(a)anthracene (DMBA)-induced breast cancer in the rat. Cancer Lett., 231, 43-48.
    • (2006) Cancer Lett , vol.231 , pp. 43-48
    • Lai, H.1
  • 26
    • 24944496956 scopus 로고    scopus 로고
    • Gene expression profiling of NMU-induced rat mammary tumors: Cross species comparison with human breast cancer
    • Chan,M.M. et al. (2005) Gene expression profiling of NMU-induced rat mammary tumors: Cross species comparison with human breast cancer. Carcinogenesis, 26, 1343-1353.
    • (2005) Carcinogenesis , vol.26 , pp. 1343-1353
    • Chan, M.M.1
  • 27
    • 0036685384 scopus 로고    scopus 로고
    • Quantitation of estradiol receptors alpha and beta and progesterone receptors in human breast tumors by real-time reverse transcription-polymerase chain reaction. Correlation with protein assays
    • de Cremoux,P. et al. (2002) Quantitation of estradiol receptors alpha and beta and progesterone receptors in human breast tumors by real-time reverse transcription-polymerase chain reaction. Correlation with protein assays. Biochem. Pharmacol., 64, 507-515.
    • (2002) Biochem. Pharmacol , vol.64 , pp. 507-515
    • de Cremoux, P.1
  • 28
    • 1842634581 scopus 로고    scopus 로고
    • Differential regulation of the human progesterone receptor gene through an estrogen response element half site and Sp1 sites
    • Petz,L.N. et al. (2004) Differential regulation of the human progesterone receptor gene through an estrogen response element half site and Sp1 sites. J. Steroid Biochem. Mol. Biol., 88, 113-122.
    • (2004) J. Steroid Biochem. Mol. Biol , vol.88 , pp. 113-122
    • Petz, L.N.1
  • 29
    • 0027096763 scopus 로고
    • Optimization of estrogen growth response in MCF-7 cells
    • Wiese,T.E. et al. (1992) Optimization of estrogen growth response in MCF-7 cells. In Vitro Cell. Dev. Biol., 28A, 595-602.
    • (1992) In Vitro Cell. Dev. Biol , vol.28 A , pp. 595-602
    • Wiese, T.E.1
  • 30
    • 33646930743 scopus 로고    scopus 로고
    • Fulvestram (ICI 182,780)-dependent interacting proteins mediate immobilization and degradation of estrogen receptor-alpha
    • Long,X. et al. (2006) Fulvestram (ICI 182,780)-dependent interacting proteins mediate immobilization and degradation of estrogen receptor-alpha. J. Biol. Chem., 281, 9607-9615.
    • (2006) J. Biol. Chem , vol.281 , pp. 9607-9615
    • Long, X.1
  • 31
    • 33748755657 scopus 로고    scopus 로고
    • The Forkhead box M1 protein regulates the transcription of the estrogen receptor alpha in breast cancer cells
    • Madureira,P.A. et al. (2006) The Forkhead box M1 protein regulates the transcription of the estrogen receptor alpha in breast cancer cells. J. Biol. Chem., 281, 25167-25176.
    • (2006) J. Biol. Chem , vol.281 , pp. 25167-25176
    • Madureira, P.A.1
  • 32
    • 34447130861 scopus 로고    scopus 로고
    • Positive cross-regulatory loop ties GATA-3 to estrogen receptor alpha expression in breast cancer
    • Eeckhoute,J. et al. (2007) Positive cross-regulatory loop ties GATA-3 to estrogen receptor alpha expression in breast cancer. Cancer Res., 67, 6477-6483.
    • (2007) Cancer Res , vol.67 , pp. 6477-6483
    • Eeckhoute, J.1
  • 33
    • 38749116741 scopus 로고    scopus 로고
    • Ets-2 and C/EBP-beta are important mediators of ovine trophoblast Kunitz domain protein-1 gene expression in trophoblast
    • Chakrabarty,A. et al. (2007) Ets-2 and C/EBP-beta are important mediators of ovine trophoblast Kunitz domain protein-1 gene expression in trophoblast. BMC Mol. Biol., 8, 14.
    • (2007) BMC Mol. Biol , vol.8 , pp. 14
    • Chakrabarty, A.1
  • 34
    • 0344643402 scopus 로고    scopus 로고
    • C/EBP alpha and Ets protein family members regulate the human myeloid IgA Fc receptor (Fe alpha R, CD89) promoter
    • Shimokawa,T. et al. (2003) C/EBP alpha and Ets protein family members regulate the human myeloid IgA Fc receptor (Fe alpha R, CD89) promoter. J. Immunol., 170, 2564-2572.
    • (2003) J. Immunol , vol.170 , pp. 2564-2572
    • Shimokawa, T.1
  • 35
    • 0034490479 scopus 로고    scopus 로고
    • A role for both Ets and C/EBP transcription factors and mRNA stabilization in the MAPK-dependent increase in p21 (Cip-1/WAF1/mda6) protein levels in primary hepatocytes
    • Park,J.S. et al. (2000) A role for both Ets and C/EBP transcription factors and mRNA stabilization in the MAPK-dependent increase in p21 (Cip-1/WAF1/mda6) protein levels in primary hepatocytes. Mol. Biol. Cell, 11, 2915-2932.
    • (2000) Mol. Biol. Cell , vol.11 , pp. 2915-2932
    • Park, J.S.1
  • 36
    • 0037314762 scopus 로고    scopus 로고
    • Estrogen receptor (ER)-beta reduces ERalpha-regulated gene transcription, supporting a "ying yang", relationship between ERalpha and ERbeta. in mice
    • Lindberg,M.K. et al. (2003) Estrogen receptor (ER)-beta reduces ERalpha-regulated gene transcription, supporting a "ying yang", relationship between ERalpha and ERbeta. in mice. Mol. Endocrinol. 17, 203-208.
    • (2003) Mol. Endocrinol , vol.17 , pp. 203-208
    • Lindberg, M.K.1
  • 37
    • 0014300621 scopus 로고
    • Influence of five anti-cancer drugs on the induction and growth of experimental mammary cancers: Comparison with ovariectomy
    • Rees,E.D. et al. (1968) Influence of five anti-cancer drugs on the induction and growth of experimental mammary cancers: Comparison with ovariectomy. Cancer, 21, 1029-1041.
    • (1968) Cancer , vol.21 , pp. 1029-1041
    • Rees, E.D.1


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