Aminoglycoside activity observed on single pre-translocation ribosome complexes

Nature Chemical Biology

Volumn 6, Issue 1, 2010, Pages 54-62

  Feldman, Michael B ^a,b   Terry, Daniel S ^a,c   Altman, Roger B ^a   Blanchard, Scott C ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b ROCKEFELLER UNIVERSITY   (United States)

^c Tri Institutional Training Program in Computational Biology and Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOGLYCOSIDE; GENTAMICIN C; KANAMYCIN A; KANAMYCIN B; NEOMYCIN; PAROMOMYCIN; RIBOSOME DNA; TRANSFER RNA; KANAMYCIN; OLIGONUCLEOTIDE; RNA;

ANTIMICROBIAL ACTIVITY; ARTICLE; BINDING SITE; DRUG CONFORMATION; DRUG PROTEIN BINDING; DRUG STABILITY; DRUG STRUCTURE; FLUOROMETRY; GENETIC RESISTANCE; MOLECULAR DYNAMICS; MUTATION; PLEIOTROPY; PRIORITY JOURNAL; RIBOSOME; RNA CONFORMATION; RNA TRANSPORT; SIGNAL TRANSDUCTION; SINGLE MOLECULE FLUORESCENCE RESONANCE ENERGY TRANSFER; CHEMICAL STRUCTURE; CHEMISTRY; CRYOELECTRON MICROSCOPY; FLUORESCENCE RESONANCE ENERGY TRANSFER; KINETICS; METABOLISM; NUCLEOTIDE SEQUENCE; PROTEIN BINDING; PROTEIN TRANSPORT; REPRODUCIBILITY;

AMINOGLYCOSIDES; BINDING SITES; CONSERVED SEQUENCE; CRYOELECTRON MICROSCOPY; FLUORESCENCE RESONANCE ENERGY TRANSFER; KANAMYCIN; KINETICS; MODELS, MOLECULAR; MUTATION; NEOMYCIN; OLIGONUCLEOTIDES; PROTEIN BINDING; PROTEIN TRANSPORT; REPRODUCIBILITY OF RESULTS; RNA; RNA, TRANSFER;

EID: 77950391683     PISSN: 15524450     EISSN: 15524469     Source Type: Journal    
DOI: 10.1038/nchembio.274     Document Type: Article

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