Chemogenomic and transcriptome analysis identifies mode of action of the chemosensitizing agent CTBT (7-chlorotetrazolo[5,1-c]benzo[1,2,4]triazine)

BMC Genomics

Volumn 11, Issue 1, 2010, Pages

  Batova, Monika ^a,c   Klobucnikova, Vlasta ^b   Oblasova, Zuzana ^a   Gregan, Juraj ^c   Zahradnik, Pavol ^a   Hapala, Ivan ^b   Subik, Julius ^a   Schüller, Christoph ^c  

^a Faculty of Natural Sciences   (Slovakia)

^b INSTITUTE OF CHEMISTRY   (Slovakia)

^c UNIVERSITY OF VIENNA   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

7 CHLOROTETRAZOLO[1,5 C]BENZO[1,2,4]TRIAZINE; ANTIFUNGAL AGENT; CHAPERONE; COPPER ZINC SUPEROXIDE DISMUTASE; GENOMIC DNA; MANGANESE SUPEROXIDE DISMUTASE; OXYGEN; PROTEIN CCS1; SUPEROXIDE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR CIN5; TRANSCRIPTION FACTOR SKN7; TRANSCRIPTION FACTOR YAP1; TRANSCRIPTION FACTOR YAP7; TRANSCRIPTOME; UNCLASSIFIED DRUG; 7 CHLOROTETRAZOLO(5,1 C)BENZO(1,2,4)TRIAZINE; 7-CHLOROTETRAZOLO(5,1-C)BENZO(1,2,4)TRIAZINE; FUNGAL DNA; MITOCHONDRIAL DNA; TRIAZINE DERIVATIVE;

ACUTE STRESS; ANTIFUNGAL ACTIVITY; ANTIFUNGAL SUSCEPTIBILITY; ARTICLE; CELL NUCLEUS; CHROMATIN; CONTROLLED STUDY; DELETION MUTANT; DNA REPAIR; DRUG MECHANISM; DRUG STRUCTURE; EARLY RESPONSE GENE; FUNGUS GROWTH; GENE DELETION; GENE EXPRESSION PROFILING; GENE FUNCTION; GENE REPRESSION; GENETIC TRANSCRIPTION; GROWTH INHIBITION; HAPLOIDY; LIPOGENESIS; MITOCHONDRION; NONHUMAN; OXIDATION; OXIDATIVE STRESS; PROTEIN LOCALIZATION; RESPIRATORY CHAIN; YEAST CELL; DNA MICROARRAY; DRUG EFFECT; GENETICS; METABOLISM; MICROBIOLOGICAL EXAMINATION; SACCHAROMYCES CEREVISIAE;

CANDIDA ALBICANS; CANDIDA GLABRATA; SACCHAROMYCES CEREVISIAE;

ANTIFUNGAL AGENTS; DNA, FUNGAL; DNA, MITOCHONDRIAL; GENE EXPRESSION PROFILING; MICROBIAL SENSITIVITY TESTS; MITOCHONDRIA; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OXIDATIVE STRESS; SACCHAROMYCES CEREVISIAE; SEQUENCE DELETION; SUPEROXIDES; TRIAZINES;

EID: 77950383672     PISSN: None     EISSN: 14712164     Source Type: Journal    
DOI: 10.1186/1471-2164-11-153     Document Type: Article

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