Overexpressed Sod1p acts either to reduce or to increase the lifespans and stress resistance of yeast, depending on whether it is Cu2+-deficient or an active Cu,Zn-superoxide dismutase

Aging Cell

Volumn 4, Issue 1, 2005, Pages 41-52

  Harris, Nicholas ^a   Bachler, Marcus ^a,c   Costa, Vitor ^b   Mollapour, Mehdi ^a   Moradas Ferreira, Pedro ^b   Piper, Peter W ^a  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

^b UNIVERSITY OF PORTO   (Portugal)

^c UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Cu,Zn superoxide dismutase; Oxidative stress; Replicative lifespan; Yeast chronological lifespan

Indexed keywords

CHAPERONE; COPPER ION; COPPER ZINC SUPEROXIDE DISMUTASE; REACTIVE OXYGEN METABOLITE; CATALASE; CCS1 PROTEIN, S CEREVISIAE; COPPER; MANGANESE SUPEROXIDE DISMUTASE; SACCHAROMYCES CEREVISIAE PROTEIN; SUPEROXIDE DISMUTASE;

ARTICLE; CCS1 GENE; CELL DIVISION; CELL GROWTH; CELL SURVIVAL; CONTROLLED STUDY; CTT1 GENE; FUNGAL GENE; GENE OVEREXPRESSION; LIFESPAN; METAZOON; NONHUMAN; OXIDATIVE STRESS; PHENOTYPE; PRIORITY JOURNAL; SOD1P GENE; SOD2 GENE; SPONTANEOUS MUTATION; STRESS; TEMPERATURE; YEAST; CELL CYCLE G0 PHASE; GENE EXPRESSION; GENETICS; GENOTYPE; GROWTH, DEVELOPMENT AND AGING; METABOLISM; OXIDATION REDUCTION REACTION; PHYSIOLOGY; SACCHAROMYCES CEREVISIAE; TIME;

METAZOA;

CATALASE; COPPER; G0 PHASE; GENE EXPRESSION; GENOTYPE; MOLECULAR CHAPERONES; OXIDATION-REDUCTION; OXIDATIVE STRESS; PHENOTYPE; REACTIVE OXYGEN SPECIES; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SUPEROXIDE DISMUTASE; TIME FACTORS;

EID: 23844463622     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/j.1474-9726.2005.00142.x     Document Type: Article

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