Preparation of 16β-estradiol derivative libraries as bisubstrate inhibitors of 17β-hydroxysteroid dehydrogenase type 1 using the multidetachable sulfamate linker

Molecules

Volumn 15, Issue 3, 2010, Pages 1590-1631

  Bérubé, Marie ^a   Delagoutte, Florian ^a   Poirier, Donald ^a  

^a LAVAL UNIVERSITY   (Canada)

Author keywords

17 HSD; Inhibitor; Solid phase synthesis; Steroid; Sulfamate linker

Indexed keywords

7 BETA HYDROXYSTEROID DEHYDROGENASE; 7 BETA-HYDROXYSTEROID DEHYDROGENASE; DRUG DERIVATIVE; ENZYME INHIBITOR; ESTRADIOL; ESTRADIOL 16; ESTRADIOL-16; HYDROXYSTEROID DEHYDROGENASE;

ARTICLE; CELL LINE; CHEMISTRY; DRUG ANTAGONISM; ENZYME SPECIFICITY; HUMAN;

CELL LINE; ENZYME INHIBITORS; ESTRADIOL; HUMANS; HYDROXYSTEROID DEHYDROGENASES; SUBSTRATE SPECIFICITY;

EID: 77950356448     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules15031590     Document Type: Article

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