-
1
-
-
0036211230
-
Chirality: A blueprint for the future
-
Burke, D.; Henderson, D.J. Chirality: a blueprint for the future. Br. J. Anaesth., 2002, 88, 563-576.
-
(2002)
Br. J. Anaesth.
, vol.88
, pp. 563-576
-
-
Burke, D.1
Henderson, D.J.2
-
2
-
-
34548457594
-
Importance of chirality in drug therapy and pharmacy practice: Implications for psychiatry
-
Davies, N.M.; Teng, X.W. Importance of chirality in drug therapy and pharmacy practice: implications for psychiatry. Adv. Pharm., 2003, 1, 242-252.
-
(2003)
Adv. Pharm.
, vol.1
, pp. 242-252
-
-
Davies, N.M.1
Teng, X.W.2
-
3
-
-
0036130597
-
Role of chiral chromatography in therapeutic drug monitoring and in clinical and forensic toxicology
-
Williams, M.L.; Wainer, I.W. Role of chiral chromatography in therapeutic drug monitoring and in clinical and forensic toxicology. Ther. Drug. Monit., 2002, 24, 290-296.
-
(2002)
Ther. Drug. Monit.
, vol.24
, pp. 290-296
-
-
Williams, M.L.1
Wainer, I.W.2
-
4
-
-
0042020171
-
Stereoselectivity of drug-receptor interactions
-
Soudijn, W.; Van Wijngaarden, I.; Ijzerman, A.P. Stereoselectivity of drug-receptor interactions. IDrugs, 2003, 6, 43-56.
-
(2003)
IDrugs
, vol.6
, pp. 43-56
-
-
Soudijn, W.1
Van Wijngaarden, I.2
Ijzerman, A.P.3
-
5
-
-
45249098601
-
Chiral drugs. An overview
-
Nguyen, L.A.; He, H.; Pham-Huy, C. Chiral drugs. An overview. Int. J. Biomed. Sci., 2006, 2, 85-100.
-
(2006)
Int. J. Biomed. Sci.
, vol.2
, pp. 85-100
-
-
Nguyen, L.A.1
He, H.2
Pham-Huy, C.3
-
6
-
-
33751574640
-
Drug disposition in three dimensions: An update on stereoselectivity in pharmacokinetics
-
Brocks, D.R. Drug disposition in three dimensions: an update on stereoselectivity in pharmacokinetics. Biopharm. Drug Dispos., 2006, 27, 387-406.
-
(2006)
Biopharm. Drug Dispos.
, vol.27
, pp. 387-406
-
-
Brocks, D.R.1
-
7
-
-
34547689154
-
Chirality and pharmacokinetics: An area of neglected dimensionality?
-
Hutt, A.J. Chirality and pharmacokinetics: an area of neglected dimensionality? Drug Metab. Drug Inter., 2007, 22, 79-112.
-
(2007)
Drug Metab. Drug Inter.
, vol.22
, pp. 79-112
-
-
Hutt, A.J.1
-
8
-
-
34547193773
-
Stereoselectivity in drug metabolism
-
Lu, H. Stereoselectivity in drug metabolism. Expert Opin. Drug Metab. Toxicol., 2007, 3, 149-158.
-
(2007)
Expert Opin. Drug Metab. Toxicol.
, vol.3
, pp. 149-158
-
-
Lu, H.1
-
9
-
-
0034712572
-
Chiral switches
-
Tucker, G.T. Chiral switches. Lancet, 2000, 355, 1085-1087.
-
(2000)
Lancet
, vol.355
, pp. 1085-1087
-
-
Tucker, G.T.1
-
10
-
-
0035560583
-
Development and regulation of chiral drugs substances: An overview on worldwide pharmaceutical guidelines
-
Santoro, M.I.R.M.; Singh, A.K. Development and regulation of chiral drugs substances: an overview on worldwide pharmaceutical guidelines. Braz. J. Pharm. Sci., 2001, 37, 259-268.
-
(2001)
Braz. J. Pharm. Sci.
, vol.37
, pp. 259-268
-
-
Santoro, M.I.R.M.1
Singh, A.K.2
-
11
-
-
0036782116
-
Putting chirality to work: The strategy of chiral switches
-
Agranat, I.; Caner, H.; Caldwell, J. Putting chirality to work: the strategy of chiral switches. Nat. Rev. Drug. Discov., 2002, 1, 753-768.
-
(2002)
Nat. Rev. Drug. Discov.
, vol.1
, pp. 753-768
-
-
Agranat, I.1
Caner, H.2
Caldwell, J.3
-
12
-
-
0036724848
-
Malaria: Current status of control, diagnosis, treatment, and a proposed agenda for research and development
-
Guerin, P.J.; Olliaro, P.; Nosten, F.; Druilhe, P.; Laxminarayan, R.; Binka, F.; Kilama, W.L.; Ford, N.; White, N.J. Malaria: current status of control, diagnosis, treatment, and a proposed agenda for research and development. Lancet Infect. Dis., 2002, 2, 564-573.
-
(2002)
Lancet Infect. Dis.
, vol.2
, pp. 564-573
-
-
Guerin, P.J.1
Olliaro, P.2
Nosten, F.3
Druilhe, P.4
Laxminarayan, R.5
Binka, F.6
Kilama, W.L.7
Ford, N.8
White, N.J.9
-
13
-
-
0037033984
-
The economic and social burden of malaria
-
Sachs, J.; Malaney, P. The economic and social burden of malaria. Nature, 2002, 415, 680-685.
-
(2002)
Nature
, vol.415
, pp. 680-685
-
-
Sachs, J.1
Malaney, P.2
-
15
-
-
17844382146
-
Malaria
-
Greenwood, B.M.; Bojang, K.; Whitty, C.J.M.; Targett, G.A.T. Malaria. Lancet, 2005, 365, 1487-1498.
-
(2005)
Lancet
, vol.365
, pp. 1487-1498
-
-
Greenwood, B.M.1
Bojang, K.2
Whitty, C.J.M.3
Targett, G.A.T.4
-
16
-
-
0036188537
-
Clinical status and implications of antimalarial drug resistance
-
Winstanley, P.A.; Ward, S.A.; Snow, R.W. Clinical status and implications of antimalarial drug resistance. Microbes Infect., 2002, 4, 157-164.
-
(2002)
Microbes Infect.
, vol.4
, pp. 157-164
-
-
Winstanley, P.A.1
Ward, S.A.2
Snow, R.W.3
-
17
-
-
57349151132
-
Drug development for neglected diseases - The trouble with FDA review vouchers
-
Kesselheim, A.S. Drug development for neglected diseases - the trouble with FDA review vouchers. N. Engl. J. Med., 2008, 359, 1981-1983.
-
(2008)
N. Engl. J. Med.
, vol.359
, pp. 1981-1983
-
-
Kesselheim, A.S.1
-
18
-
-
0037034009
-
Medical need, scientific opportunity and the drive for antimalarial drugs
-
Ridley, R.G. Medical need, scientific opportunity and the drive for antimalarial drugs. Nature, 2002, 415, 686-693.
-
(2002)
Nature
, vol.415
, pp. 686-693
-
-
Ridley, R.G.1
-
19
-
-
0035743022
-
From classical antimalarial drugs to new compounds based on the mechanism of action of artemisinin
-
Robert, A.; Benoit-Vical, F.; Dechy-Cabaret, O.; Meunier, B. From classical antimalarial drugs to new compounds based on the mechanism of action of artemisinin. Pure Appl. Chem., 2001, 73, 1173-1188.
-
(2001)
Pure Appl. Chem.
, vol.73
, pp. 1173-1188
-
-
Robert, A.1
Benoit-Vical, F.2
Dechy-Cabaret, O.3
Meunier, B.4
-
20
-
-
0035153917
-
Quinoline antimalarials
-
Egan, T.J. Quinoline antimalarials. Expert Opin. Ther. Pat., 2001, 11, 185-209.
-
(2001)
Expert Opin. Ther. Pat.
, vol.11
, pp. 185-209
-
-
Egan, T.J.1
-
21
-
-
44349176702
-
Antimalarial drugs - What is in use and what is in the pipeline
-
Schlitzer, M. Antimalarial drugs - what is in use and what is in the pipeline. Arch. Pharm. Chem. Life Sci., 2008, 341, 149-163.
-
(2008)
Arch. Pharm. Chem. Life Sci.
, vol.341
, pp. 149-163
-
-
Schlitzer, M.1
-
22
-
-
0242406992
-
Antimalarial drug discovery: Old and new approaches
-
Rosenthal, P.J. Antimalarial drug discovery: old and new approaches. J. Exp. Biol., 2003, 206, 3735-3744.
-
(2003)
J. Exp. Biol.
, vol.206
, pp. 3735-3744
-
-
Rosenthal, P.J.1
-
23
-
-
42349104331
-
Qinghaosu (artemisinin): The price of success
-
White, N.J. Qinghaosu (artemisinin): the price of success. Science, 2008, 320, 330-334.
-
(2008)
Science
, vol.320
, pp. 330-334
-
-
White, N.J.1
-
24
-
-
0029819068
-
Clinical pharmacokinetics and metabolism of chloroquine. Focus on recent advancements
-
Ducharme, J.; Farinotti, R. Clinical pharmacokinetics and metabolism of chloroquine. Focus on recent advancements. Clin. Pharmacokinet., 1996, 31, 257-274.
-
(1996)
Clin. Pharmacokinet.
, vol.31
, pp. 257-274
-
-
Ducharme, J.1
Farinotti, R.2
-
25
-
-
0025763310
-
Absence of antimalarial activity or interaction with mefloquine enantiomers in vitro of the main human metabolite of mefloquine
-
Basco, L.K.; Gillotin, C.; Gimenez, F.; Farinotti, R.; Le Bras, J. Absence of antimalarial activity or interaction with mefloquine enantiomers in vitro of the main human metabolite of mefloquine. Trans. R. Soc. Trop. Med. Hyg., 1991, 85, 208-209.
-
(1991)
Trans. R. Soc. Trop. Med. Hyg.
, vol.85
, pp. 208-209
-
-
Basco, L.K.1
Gillotin, C.2
Gimenez, F.3
Farinotti, R.4
Le Bras, J.5
-
26
-
-
0018413960
-
Chloroquine enantiomers: Activity against P. vinckei and binding on DNA
-
Fink, E.; Minet, G.; Nickel, P. Chloroquine enantiomers: activity against P. vinckei and binding on DNA. Arzneim. Forsch., 1979, 29, 163-164.
-
(1979)
Arzneim. Forsch.
, vol.29
, pp. 163-164
-
-
Fink, E.1
Minet, G.2
Nickel, P.3
-
27
-
-
0018511696
-
Antimalarial activity in animals of the optical isomers of chloroquine diphosphate
-
Haberkorn, A.; Kraft, H.P.; Blaschke, G. Antimalarial activity in animals of the optical isomers of chloroquine diphosphate. Tropenmed. Parasitol., 1979, 30, 308-312.
-
(1979)
Tropenmed. Parasitol.
, vol.30
, pp. 308-312
-
-
Haberkorn, A.1
Kraft, H.P.2
Blaschke, G.3
-
28
-
-
0023003528
-
In vitro activity of chloroquine, the two enantiomers of chloroquine, desethylchloroquine and pyronaridine against Plasmodium falciparum
-
Fu, S.; Björkman, A.; Wåhlin, B.; Ofori-Adjei, B.; Ericsson, O.; Sjöqvist, F. In vitro activity of chloroquine, the two enantiomers of chloroquine, desethylchloroquine and pyronaridine against Plasmodium falciparum. Br. J. Clin. Pharmacol., 1986, 22, 93-96.
-
(1986)
Br. J. Clin. Pharmacol.
, vol.22
, pp. 93-96
-
-
Fu, S.1
Björkman, A.2
Wåhlin, B.3
Ofori-Adjei, B.4
Ericsson, O.5
Sjöqvist, F.6
-
29
-
-
0027607819
-
Differential binding of the enantiomers of chloroquine and quinacrine to polynucleotides: Implications for stereoselective metabolism
-
Scaria, P.V.; Craig, J.C.; Shafer, R.H. Differential binding of the enantiomers of chloroquine and quinacrine to polynucleotides: implications for stereoselective metabolism. Biopolymers, 1993, 33, 887-895.
-
(1993)
Biopolymers
, vol.33
, pp. 887-895
-
-
Scaria, P.V.1
Craig, J.C.2
Shafer, R.H.3
-
30
-
-
0026583261
-
In vitro activity of the enantiomers of mefloquine, halofantrine and enpiroline against Plasmodium falciparum
-
Basco, L.K.; Gillotin, C.; Gimenez, F.; Farinotti, R.; Le Bras, J. In vitro activity of the enantiomers of mefloquine, halofantrine and enpiroline against Plasmodium falciparum. Br. J. Clin. Pharmacol., 1992, 33, 517-520.
-
(1992)
Br. J. Clin. Pharmacol.
, vol.33
, pp. 517-520
-
-
Basco, L.K.1
Gillotin, C.2
Gimenez, F.3
Farinotti, R.4
Le Bras, J.5
-
31
-
-
0027267401
-
Plasmodium Falciparum: Role of absolute stereochemistry in the antimalarial activity of synthetic amino alcohol antimalarial agents
-
Karle, J.M.; Olmeda, R.; Gerena, L.; Milhous, W.K. Plasmodium Falciparum: role of absolute stereochemistry in the antimalarial activity of synthetic amino alcohol antimalarial agents. Exp. Parasitol., 1993, 76, 345-351.
-
(1993)
Exp. Parasitol.
, vol.76
, pp. 345-351
-
-
Karle, J.M.1
Olmeda, R.2
Gerena, L.3
Milhous, W.K.4
-
32
-
-
0027340135
-
Activity in vitro of the enantiomers of halofantrine
-
Basco, L.K.; Gillotin, C.; Gimenez, F.; Farinotti, R.; Le Bras, J. Activity in vitro of the enantiomers of halofantrine. Trans. R. Soc. Trop. Med. Hyg., 1993, 87, 78-79.
-
(1993)
Trans. R. Soc. Trop. Med. Hyg.
, vol.87
, pp. 78-79
-
-
Basco, L.K.1
Gillotin, C.2
Gimenez, F.3
Farinotti, R.4
Le Bras, J.5
-
33
-
-
0028323136
-
In vitro activity of the enantiomers of N-desbutyl derivative of halofantrine
-
Basco, L.K.; Peytavin, G.; Gimenez, F.; Genissel, B.; Farinotti, R.; Le Bras, J. In vitro activity of the enantiomers of N-desbutyl derivative of halofantrine. Trop. Med. Parasitol., 1994, 45, 45-46.
-
(1994)
Trop. Med. Parasitol.
, vol.45
, pp. 45-46
-
-
Basco, L.K.1
Peytavin, G.2
Gimenez, F.3
Genissel, B.4
Farinotti, R.5
Le Bras, J.6
-
34
-
-
0032525989
-
Activity of benflumetol and its enantiomers in fresh isolates of Plasmodium falciparum from East Africa
-
Wernsdorfer, W.H.; Landgraf, B.; Kilimali, V.A.E.B.; Wernsdorfer, G. Activity of benflumetol and its enantiomers in fresh isolates of Plasmodium falciparum from East Africa. Acta Trop., 1998, 70, 9-15.
-
(1998)
Acta Trop.
, vol.70
, pp. 9-15
-
-
Wernsdorfer, W.H.1
Landgraf, B.2
Kilimali, V.A.E.B.3
Wernsdorfer, G.4
-
35
-
-
0023190257
-
Antimalarial activity and inhibition of monoamine oxidases A and B by exo-erythrocytic antimalarials. Optical isomers of primaquine, N-acylated congeners, primaquine metabolites and 5-phenoxy-substituted analogs
-
Brossi, A.; Millet, P.; Landau, I.; Bembenek, M.E.; Abell, C.W. Antimalarial activity and inhibition of monoamine oxidases A and B by exo-erythrocytic antimalarials. Optical isomers of primaquine, N-acylated congeners, primaquine metabolites and 5-phenoxy-substituted analogs. FEBS Lett., 1987, 214, 291-294.
-
(1987)
FEBS Lett.
, vol.214
, pp. 291-294
-
-
Brossi, A.1
Millet, P.2
Landau, I.3
Bembenek, M.E.4
Abell, C.W.5
-
36
-
-
0025883963
-
Antimalarial activity of optical isomers of quinacrine dihydrochloride against chloroquine-sensitive and -resistant Plasmodium falciparum in vitro
-
Webster, R.V.; Craig, J.C.; Shyamala, V.; Kirby, G.C.; Warhursts, D.C. Antimalarial activity of optical isomers of quinacrine dihydrochloride against chloroquine-sensitive and -resistant Plasmodium falciparum in vitro. Biochem. Pharmacol., 1991, 42, S225-S227.
-
(1991)
Biochem. Pharmacol.
, vol.42
-
-
Webster, R.V.1
Craig, J.C.2
Shyamala, V.3
Kirby, G.C.4
Warhursts, D.C.5
-
37
-
-
0026769849
-
Stereochemical evaluation of the relative activities of the cinchona alkaloids against Plasmodium falciparum
-
Karle, J.M.; Karle, I.L.; Gerena, L.; Milhous, W.K. Stereochemical evaluation of the relative activities of the cinchona alkaloids against Plasmodium falciparum. Antimicrob. Agents Chemother., 1992, 36, 1538-1544.
-
(1992)
Antimicrob. Agents Chemother.
, vol.36
, pp. 1538-1544
-
-
Karle, J.M.1
Karle, I.L.2
Gerena, L.3
Milhous, W.K.4
-
38
-
-
0015978426
-
Optical isomers of aryl-2-piperidylmethanol antimalarial agents. Preparation, optical purity, and absolute stereochemistry
-
Carroll, F.I.; Blackwell, J.T. Optical isomers of aryl-2- piperidylmethanol antimalarial agents. Preparation, optical purity, and absolute stereochemistry. J. Med. Chem., 1974, 17, 210-219.
-
(1974)
J. Med. Chem.
, vol.17
, pp. 210-219
-
-
Carroll, F.I.1
Blackwell, J.T.2
-
39
-
-
0028827324
-
The chemotherapy of rodent malaria. LII. Response of Plasmodium yoelii ssp. NS to mefloquine and its enantiomers
-
Peters, W.; Robinson, B.L.; Mittelholzer, M.L.; Crevoisier, C.; Stürchler, D. The chemotherapy of rodent malaria. LII. Response of Plasmodium yoelii ssp. NS to mefloquine and its enantiomers. Ann. Trop. Med. Parasitol., 1995, 89, 465-468.
-
(1995)
Ann. Trop. Med. Parasitol.
, vol.89
, pp. 465-468
-
-
Peters, W.1
Robinson, B.L.2
Mittelholzer, M.L.3
Crevoisier, C.4
Stürchler, D.5
-
40
-
-
0017372529
-
Comparison of the curative antimalarial activities and toxicities of primaquine and its d and 1 isomers
-
Schmidt, L.H.; Alexander, S.; Allen, L.; Rasco, J. Comparison of the curative antimalarial activities and toxicities of primaquine and its d and 1 isomers. Antimicro. Agents Chemoter., 1977, 12, 51-60.
-
(1977)
Antimicro. Agents Chemoter.
, vol.12
, pp. 51-60
-
-
Schmidt, L.H.1
Alexander, S.2
Allen, L.3
Rasco, J.4
-
41
-
-
44449113132
-
Antiparasitic activities and toxicities of individual enantiomers of the 8-aminoquinoline 8-[(4-amino-1-methylbutyl)amino]-6-methoxy-4- Methyl-5-[3,4-dichlorophenoxy]quinoline succinate
-
Nanayakkara, N.P.D.; Ager Jr., A.L.; Bartlett, M.S.; Yardley, V.; Croft, S.L.; Khan, I.A.; McChesney, J.D.; Walker, L.A. Antiparasitic activities and toxicities of individual enantiomers of the 8-aminoquinoline 8-[(4-amino-1-methylbutyl)amino]-6-methoxy-4- methyl-5-[3,4-dichlorophenoxy] quinoline succinate. Antimicrob. Agents Chemother., 2008, 52, 2130-2137.
-
(2008)
Antimicrob. Agents Chemother.
, Issue.52
, pp. 2130-2137
-
-
Nanayakkara, N.P.D.1
Ager Jr., A.L.2
Bartlett, M.S.3
Yardley, V.4
Croft, S.L.5
Khan, I.A.6
McChesney, J.D.7
Walker, L.A.8
-
42
-
-
0028034101
-
Stereoselective inhibition by chloroquine of histamine Nmethyltransferase in the human liver and brain
-
Donatelli, P.; Marchi, G.; Pacifici, G.M.; Giuliani, L.; Gustafsson, L.L. Stereoselective inhibition by chloroquine of histamine Nmethyltransferase in the human liver and brain. Eur. J. Clin. Pharmacol., 1994, 47, 345-349.
-
(1994)
Eur. J. Clin. Pharmacol.
, vol.47
, pp. 345-349
-
-
Donatelli, P.1
Marchi, G.2
Pacifici, G.M.3
Giuliani, L.4
Gustafsson, L.L.5
-
43
-
-
0033601472
-
Inhibition of insulin metabolism by hydroxychloroquine and its enantiomers in cytosolic fraction of liver homogenates from healthy and diabetic rats
-
Emami, J.; Pasutto, F.M.; Mercer, J.R.; Jamali, F. Inhibition of insulin metabolism by hydroxychloroquine and its enantiomers in cytosolic fraction of liver homogenates from healthy and diabetic rats. Life Sci., 1999, 64, 325-335.
-
(1999)
Life Sci.
, vol.64
, pp. 325-335
-
-
Emami, J.1
Pasutto, F.M.2
Mercer, J.R.3
Jamali, F.4
-
44
-
-
0023093544
-
Stereospecific inhibition of cholinesterases by mefloquine enantiomers
-
Ngiam, T.L.; Go, M.L. Stereospecific inhibition of cholinesterases by mefloquine enantiomers. Chem. Pharm. Bull., 1987, 35, 409-412.
-
(1987)
Chem. Pharm. Bull.
, vol.35
, pp. 409-412
-
-
Ngiam, T.L.1
Go, M.L.2
-
45
-
-
0027293589
-
Pharmacological activity and structure-activity relationship of (+/-)-erythromefloquine and related compounds on the isolated mouse phrenic nerve diaphragm preparation
-
Go, M.L.; Lee, H.S.; Ngiam, T.L. Pharmacological activity and structure-activity relationship of (+/-)-erythromefloquine and related compounds on the isolated mouse phrenic nerve diaphragm preparation. Biol. Pharm. Bull., 1993, 16, 668-674.
-
(1993)
Biol. Pharm. Bull.
, vol.16
, pp. 668-674
-
-
Go, M.L.1
Lee, H.S.2
Ngiam, T.L.3
-
46
-
-
0034672468
-
Interactions of racemic mefloquine and its enantiomers with P-glycoprotein in an immortalised rat brain capillary endothelial cell line, GPNT
-
Pham, Y.T.; Régina, A.; Farinotti, R.; Couraud, P.O.; Wainer, I.W.; Roux, F.; Gimenez, F. Interactions of racemic mefloquine and its enantiomers with P-glycoprotein in an immortalised rat brain capillary endothelial cell line, GPNT. Biochim. Biophys. Acta, 2000, 1524, 212-219.
-
(2000)
Biochim. Biophys. Acta
, vol.1524
, pp. 212-219
-
-
Pham, Y.T.1
Régina, A.2
Farinotti, R.3
Couraud, P.O.4
Wainer, I.W.5
Roux, F.6
Gimenez, F.7
-
47
-
-
0038340656
-
Differential inhibition of prion propagation by enantiomers of quinacrine
-
Ryou, C.; Legname, G.; Peretz, D.; Craig, J.C.; Baldwin, M.A.; Prusiner, S.B. Differential inhibition of prion propagation by enantiomers of quinacrine. Lab. Invest., 2003, 83, 837-843.
-
(2003)
Lab. Invest.
, vol.83
, pp. 837-843
-
-
Ryou, C.1
Legname, G.2
Peretz, D.3
Craig, J.C.4
Baldwin, M.A.5
Prusiner, S.B.6
-
48
-
-
0028828631
-
Effects of chloroquine and its enantiomers on the development of rat embryos in vitro
-
Tagoe, C.N.B.; Ofori-Adjei, D. Effects of chloroquine and its enantiomers on the development of rat embryos in vitro. Teratology, 1995, 52, 137-142.
-
(1995)
Teratology
, vol.52
, pp. 137-142
-
-
Tagoe, C.N.B.1
Ofori-Adjei, D.2
-
49
-
-
0023022091
-
Protein binding of chloroquine enantiomers and desethylchloroquine
-
Ofori-Adjei, D.; Ericsson, Ö.; Lindström, B.; Sjöqvist, F. Protein binding of chloroquine enantiomers and desethylchloroquine. Br. J. Clin. Pharmacol., 1986, 22, 356-358.
-
(1986)
Br. J. Clin. Pharmacol.
, vol.22
, pp. 356-358
-
-
Ofori-Adjei, D.1
Ericsson, Ö.2
Lindström, B.3
Sjöqvist, F.4
-
50
-
-
0027404736
-
Stereoselective pharmacokinetic properties of chloroquine and de-ethylchloroquine in humans
-
Augustijns, P.; Verbeke, N. Stereoselective pharmacokinetic properties of chloroquine and de-ethylchloroquine in humans. Clin. Pharmacokinet., 1993, 24, 259-269.
-
(1993)
Clin. Pharmacokinet.
, vol.24
, pp. 259-269
-
-
Augustijns, P.1
Verbeke, N.2
-
51
-
-
0028001131
-
Plasma concentrations of the enantiomers of halofantrine and its main metabolite in malaria patients
-
Gimenez, F.; Gillotin, C.; Basco, L.K.; Bouchaud, O.; Aubry, A.F.; Wainer, I.W.; Le Bras, J.; Farinotti, R. Plasma concentrations of the enantiomers of halofantrine and its main metabolite in malaria patients. Eur. J. Clin. Pharmacol., 1994, 46, 561-562.
-
(1994)
Eur. J. Clin. Pharmacol.
, vol.46
, pp. 561-562
-
-
Gimenez, F.1
Gillotin, C.2
Basco, L.K.3
Bouchaud, O.4
Aubry, A.F.5
Wainer, I.W.6
Le Bras, J.7
Farinotti, R.8
-
52
-
-
0027152178
-
Plasma protein binding of the enantiomers of hydroxychloroquine and metabolites
-
McLachlan, A.J.; Cutler, D J.; Tett, S.E. Plasma protein binding of the enantiomers of hydroxychloroquine and metabolites. Eur. J. Clin. Pharmacol., 1993, 44, 481-484.
-
(1993)
Eur. J. Clin. Pharmacol.
, vol.44
, pp. 481-484
-
-
McLachlan, A.J.1
Cutler, D.J.2
Tett, S.E.3
-
53
-
-
0027209525
-
Disposition of the enantiomers of hydroxychloroquine in patients with rheumatoid arthritis following multiple doses of the racemate
-
McLachlan, A.J.; Tett, S.E.; Cutler, D.J.; Day, R.O. Disposition of the enantiomers of hydroxychloroquine in patients with rheumatoid arthritis following multiple doses of the racemate. Br. J. Clin. Pharmacol., 1993, 36, 78-81.
-
(1993)
Br. J. Clin. Pharmacol.
, vol.36
, pp. 78-81
-
-
McLachlan, A.J.1
Tett, S.E.2
Cutler, D.J.3
Day, R.O.4
-
54
-
-
0028148459
-
Hematologic disposition of hydroxychloroquine enantiomers
-
Brocks, D.R.; Skeith, K.J.; Johnston, C.; Emamibafrani, J.; Davis, P.; Russell, A.S.; Jamali, F. Hematologic disposition of hydroxychloroquine enantiomers. J. Clin. Pharmacol., 1994, 34, 1088-1097.
-
(1994)
J. Clin. Pharmacol.
, vol.34
, pp. 1088-1097
-
-
Brocks, D.R.1
Skeith, K.J.2
Johnston, C.3
Emamibafrani, J.4
Davis, P.5
Russell, A.S.6
Jamali, F.7
-
55
-
-
0028235352
-
Disposition and absorption of hydroxychloroquine enantiomers following a single dose of the racemate
-
McLachlan, A.J.; Tett, S.E.; Cutler, D.J.; Day, R.O. Disposition and absorption of hydroxychloroquine enantiomers following a single dose of the racemate. Chirality, 1994, 6, 360-364.
-
(1994)
Chirality
, vol.6
, pp. 360-364
-
-
McLachlan, A.J.1
Tett, S.E.2
Cutler, D.J.3
Day, R.O.4
-
56
-
-
0028263366
-
Pharmacokinetics and pharmacodynamics of hydroxychloroquine enantiomers in patients with rheumatoid arthritis receiving multiple doses of racemate
-
Tett, S.E.; McLachlan, A.J.; Cutler, D.J.; Day, R.O. Pharmacokinetics and pharmacodynamics of hydroxychloroquine enantiomers in patients with rheumatoid arthritis receiving multiple doses of racemate. Chirality, 1994, 6, 355-359.
-
(1994)
Chirality
, vol.6
, pp. 355-359
-
-
Tett, S.E.1
McLachlan, A.J.2
Cutler, D.J.3
Day, R.O.4
-
57
-
-
0029084445
-
Enantioselective disposition of hydroxychloroquine after a single oral dose of the racemate to healthy subjects
-
Ducharme, J.; Fieger, H.; Ducharme, M.P.; Khalil, S.K.W.; Wainer, I.W. Enantioselective disposition of hydroxychloroquine after a single oral dose of the racemate to healthy subjects. Br. J. Clin. Pharmacol., 1995, 40, 127-133.
-
(1995)
Br. J. Clin. Pharmacol.
, vol.40
, pp. 127-133
-
-
Ducharme, J.1
Fieger, H.2
Ducharme, M.P.3
Khalil, S.K.W.4
Wainer, I.W.5
-
58
-
-
0028026661
-
Whole blood concentrations of mefloquine enantiomers in healthy Thai volunteers
-
Martin, C.; Gimenez, F.; Bangchang, K.N.; Karbwang, J.; Wainer, I.W.; Farinotti, R. Whole blood concentrations of mefloquine enantiomers in healthy Thai volunteers. Eur. J. Clin. Pharmacol., 1994, 47, 85-87.
-
(1994)
Eur. J. Clin. Pharmacol.
, vol.47
, pp. 85-87
-
-
Martin, C.1
Gimenez, F.2
Bangchang, K.N.3
Karbwang, J.4
Wainer, I.W.5
Farinotti, R.6
-
59
-
-
0027981490
-
Stereoselective pharmacokinetics of mefloquine in healthy caucasians after multiple doses
-
Gimenez, F.; Pennie, R.A.; Koren, G.; Crevoisier, C.; Wainer, I.W.; Farinotti, R. Stereoselective pharmacokinetics of mefloquine in healthy caucasians after multiple doses. J. Pharm. Sci., 1994, 83, 824-827.
-
(1994)
J. Pharm. Sci.
, vol.83
, pp. 824-827
-
-
Gimenez, F.1
Pennie, R.A.2
Koren, G.3
Crevoisier, C.4
Wainer, I.W.5
Farinotti, R.6
-
60
-
-
0029989825
-
Stereoselective pharmacokinetics of mefloquine in young children
-
Bourahla, A.; Martin, C.; Gimenez, F.; Singhasivanon, V.; Attanath, P.; Sabchearon, A.; Chongsuphajaisiddhi, T.; Farinotti, R. Stereoselective pharmacokinetics of mefloquine in young children. Eur. J. Clin. Pharmacol., 1996, 50, 241-244.
-
(1996)
Eur. J. Clin. Pharmacol.
, vol.50
, pp. 241-244
-
-
Bourahla, A.1
Martin, C.2
Gimenez, F.3
Singhasivanon, V.4
Attanath, P.5
Sabchearon, A.6
Chongsuphajaisiddhi, T.7
Farinotti, R.8
-
61
-
-
9444226519
-
Mefloquine tolerability during chemoprophylaxis: Focus on adverse event assessments, stereochemistry and compliance
-
Schlagenhauf, P.; Steffen, R.; Lobel, H.; Johnson, R.; Letz, R.; Tschopp, A.; Vranjes, N.; Bergqvist, Y.; Ericsson, Ö.; Hellgren, U.; Rombo, L.; Mannino, S.; Handschin, J.; Stürchler, D. Mefloquine tolerability during chemoprophylaxis: focus on adverse event assessments, stereochemistry and compliance. Trop. Med. Int. Health, 1996, 1, 485-494.
-
(1996)
Trop. Med. Int. Health
, vol.1
, pp. 485-494
-
-
Schlagenhauf, P.1
Steffen, R.2
Lobel, H.3
Johnson, R.4
Letz, R.5
Tschopp, A.6
Vranjes, N.7
Bergqvist, Y.8
Ericsson, Ö.9
Hellgren, U.10
Rombo, L.11
Mannino, S.12
Handschin, J.13
Stürchler, D.14
-
62
-
-
0030852802
-
Enantioselective pharmacokinetics of mefloquine during long-term intake of the prophylactic dose
-
Hellgren, U.; Berggren-Palme, I.; Bergqvist, Y.; Jerling, M. Enantioselective pharmacokinetics of mefloquine during long-term intake of the prophylactic dose. Br. J. Clin. Pharmacol., 1996, 44, 119-124.
-
(1996)
Br. J. Clin. Pharmacol.
, vol.44
, pp. 119-124
-
-
Hellgren, U.1
Berggren-Palme, I.2
Bergqvist, Y.3
Jerling, M.4
-
63
-
-
0032896317
-
Cerebral uptake of mefloquine enantiomers in fatal cerebral malaria
-
Pham, Y.T.; Nosten, F.; Farinotti, R.; White, N.J.; Gimenez, F. Cerebral uptake of mefloquine enantiomers in fatal cerebral malaria. Int. J. Clin. Pharmacol. Ther., 1999, 37, 58-61.
-
(1999)
Int. J. Clin. Pharmacol. Ther.
, vol.37
, pp. 58-61
-
-
Pham, Y.T.1
Nosten, F.2
Farinotti, R.3
White, N.J.4
Gimenez, F.5
-
64
-
-
0026637032
-
Stereoselectivity in the disposition of chloroquine and desethylchloroquine in rabbits
-
Augustijns, P.; Verbeke, N. Stereoselectivity in the disposition of chloroquine and desethylchloroquine in rabbits. Arzneim. Forsch., 1992, 42, 825-828.
-
(1992)
Arzneim. Forsch.
, vol.42
, pp. 825-828
-
-
Augustijns, P.1
Verbeke, N.2
-
65
-
-
0033059353
-
Stereoselective de-ethylation of chloroquine in rat liver microsomes
-
Augustijns, P.; Peeters, L.; Croes, K.; Verbeeck, R.K. Stereoselective de-ethylation of chloroquine in rat liver microsomes. Eur. J. Drug Metab. Pharmacokinet., 1999, 24, 105-108.
-
(1999)
Eur. J. Drug Metab. Pharmacokinet.
, vol.24
, pp. 105-108
-
-
Augustijns, P.1
Peeters, L.2
Croes, K.3
Verbeeck, R.K.4
-
66
-
-
0033031151
-
Pharmacokinetics of halofantrine in the rat: Stereoselectivity and interspecies comparisons
-
Brocks, D.R.; Toni, J.W. Pharmacokinetics of halofantrine in the rat: stereoselectivity and interspecies comparisons. Biopharm. Drug Dispos., 1999, 20, 165-169.
-
(1999)
Biopharm. Drug Dispos.
, vol.20
, pp. 165-169
-
-
Brocks, D.R.1
Toni, J.W.2
-
67
-
-
0034429628
-
Stereoselective pharmacokinetics of desbutylhalofantrine, a metabolite of halofantrine, in the rat after administration of the racemic metabolite or parent drug
-
Brocks, D.R. Stereoselective pharmacokinetics of desbutylhalofantrine, a metabolite of halofantrine, in the rat after administration of the racemic metabolite or parent drug. Biopharm. Drug Dispos., 2000, 21, 365-371.
-
(2000)
Biopharm. Drug Dispos.
, vol.21
, pp. 365-371
-
-
Brocks, D.R.1
-
68
-
-
0028238596
-
Stereoselective distribution of hydroxychloroquine in the rabbit following single and multiple oral doses of the racemate and the separate enantiomers
-
Ducharme, J.; Wainer, I.W.; Parenteau, H.I. ; Rodman, J.H. Stereoselective distribution of hydroxychloroquine in the rabbit following single and multiple oral doses of the racemate and the separate enantiomers. Chirality, 1994, 6, 337-346.
-
(1994)
Chirality
, vol.6
, pp. 337-346
-
-
Ducharme, J.1
Wainer, I.W.2
Parenteau, H.I.3
Rodman, J.H.4
-
69
-
-
0028359048
-
Distribution of the enantiomers of hydroxychloroquine and its metabolites in ocular tissues of the rabbit after oral administration of racemic hydroxychloroquine
-
Wainer, I.W.; Chen, J.C.; Parenteau, H.; Abdullah, S.; Ducharme, J.; Fieger, H.; Iredale, J. Distribution of the enantiomers of hydroxychloroquine and its metabolites in ocular tissues of the rabbit after oral administration of racemic hydroxychloroquine. Chirality, 1994, 6, 347-354.
-
(1994)
Chirality
, vol.6
, pp. 347-354
-
-
Wainer, I.W.1
Chen, J.C.2
Parenteau, H.3
Abdullah, S.4
Ducharme, J.5
Fieger, H.6
Iredale, J.7
-
70
-
-
0029557929
-
Stereoselective disposition of hydroxychloroquine and its metabolites in rats
-
Wei, Y.; Nygard, G.A.; Ellertson, S.L.; Khalil, S.K.W. Stereoselective disposition of hydroxychloroquine and its metabolites in rats. Chirality, 1995, 7, 598-604.
-
(1995)
Chirality
, vol.7
, pp. 598-604
-
-
Wei, Y.1
Nygard, G.A.2
Ellertson, S.L.3
Khalil, S.K.W.4
-
71
-
-
0031750422
-
Effect of experimental diabetes mellitus and arthritis on the pharmacokinetics of hydroxychloroquine enantiomers in rats
-
Emami, J.; Pasutto, F.M.; Jamali, F. Effect of experimental diabetes mellitus and arthritis on the pharmacokinetics of hydroxychloroquine enantiomers in rats. Pharm. Res., 1998, 15, 897-903.
-
(1998)
Pharm. Res.
, vol.15
, pp. 897-903
-
-
Emami, J.1
Pasutto, F.M.2
Jamali, F.3
-
72
-
-
15144361805
-
Separation and metabolism of mefloquine enantiomers
-
Koch, M.; Blaschke, G. Separation and metabolism of mefloquine enantiomers. Arch. Pharm., 1990, 323, 749.
-
(1990)
Arch. Pharm.
, vol.323
, pp. 749
-
-
Koch, M.1
Blaschke, G.2
-
73
-
-
0030690220
-
Stereoselective passage of mefloquine through the blood-brain barrier in the rat
-
Baudry, S.; Pham, Y.T.; Baune, B.; Vidrequin, S.; Crevoisier, C.; Gimenez, F.; Farinotti, R. Stereoselective passage of mefloquine through the blood-brain barrier in the rat. J. Pharm. Pharmacol., 1997, 49, 1086-1090.
-
(1997)
J. Pharm. Pharmacol.
, vol.49
, pp. 1086-1090
-
-
Baudry, S.1
Pham, Y.T.2
Baune, B.3
Vidrequin, S.4
Crevoisier, C.5
Gimenez, F.6
Farinotti, R.7
-
74
-
-
0024242183
-
Differential metabolism of the enantiomers of primaquine
-
Baker, J.K.; McChesney, J.D. Differential metabolism of the enantiomers of primaquine. J. Pharm. Sci., 1988, 77, 380-382.
-
(1988)
J. Pharm. Sci.
, vol.77
, pp. 380-382
-
-
Baker, J.K.1
McChesney, J.D.2
-
75
-
-
0346729710
-
Stereoselectivity in the pharmacodynamics and pharmacokinetics of the chiral antimalarial drugs
-
Brocks, D.R.; Mehvar, R. Stereoselectivity in the pharmacodynamics and pharmacokinetics of the chiral antimalarial drugs. Clin. Pharmacokinet., 2003, 42, 1359-1382.
-
(2003)
Clin. Pharmacokinet.
, vol.42
, pp. 1359-1382
-
-
Brocks, D.R.1
Mehvar, R.2
-
76
-
-
31644435174
-
Chiral separation principles in chromatographic and electromigration techniques
-
Gübitz, G.; Schmid, M.G. Chiral separation principles in chromatographic and electromigration techniques. Mol. Biotechnol., 2006, 32, 159-180.
-
(2006)
Mol. Biotechnol.
, vol.32
, pp. 159-180
-
-
Gübitz, G.1
Schmid, M.G.2
-
77
-
-
0037080854
-
Pharmaceutical and biomedical applications of enantioseparations using liquid chromatographic techniques
-
Haginaka, J. Pharmaceutical and biomedical applications of enantioseparations using liquid chromatographic techniques. J. Pharm. Biomed. Anal., 2002, 27, 357-372.
-
(2002)
J. Pharm. Biomed. Anal.
, vol.27
, pp. 357-372
-
-
Haginaka, J.1
-
78
-
-
0035717211
-
Chiral separation by chromatographic and electromigration techniques. A review
-
Gübitz, G.; Schmid, M.G. Chiral separation by chromatographic and electromigration techniques. A review. Biopharm. Drug Dispos., 2001, 22, 291-336.
-
(2001)
Biopharm. Drug Dispos.
, vol.22
, pp. 291-336
-
-
Gübitz, G.1
Schmid, M.G.2
-
79
-
-
17044426351
-
A practical guide to HPLC enantioseparations for pharmaceutical compounds
-
Thompson, R. A practical guide to HPLC enantioseparations for pharmaceutical compounds. J. Liq. Chromatogr. Relat. Technol., 2005, 28, 1215-1231.
-
(2005)
J. Liq. Chromatogr. Relat. Technol.
, vol.28
, pp. 1215-1231
-
-
Thompson, R.1
-
80
-
-
17444377559
-
Enantioselective chromatography in drug discovery
-
Zhang, Y.; Wu, D.R.; Wang-Iverson, D.B.; Tymiak, A.A. Enantioselective chromatography in drug discovery. Drug Discov. Today, 2005, 10, 571-577.
-
(2005)
Drug Discov. Today
, vol.10
, pp. 571-577
-
-
Zhang, Y.1
Wu, D.R.2
Wang-Iverson, D.B.3
Tymiak, A.A.4
-
81
-
-
25844504983
-
Critical review of development, validation, and transfer for high-throughput bioanalytical LC-MS/MS methods
-
Zhou, S.; Song, Q.; Tang, Y.; Naidong, W. Critical review of development, validation, and transfer for high-throughput bioanalytical LC-MS/MS methods. Curr. Pharm. Anal., 2005, 1, 3-14.
-
(2005)
Curr. Pharm. Anal.
, vol.1
, pp. 3-14
-
-
Zhou, S.1
Song, Q.2
Tang, Y.3
Naidong, W.4
-
82
-
-
32444450845
-
Liquid separation techniques coupled with mass spectrometry for chiral analysis of pharmaceuticals compounds and their metabolites in biological fluids
-
Erny, G.L.; Cifuentes, A. Liquid separation techniques coupled with mass spectrometry for chiral analysis of pharmaceuticals compounds and their metabolites in biological fluids. J. Pharm. Biomed. Anal., 2006, 40, 509-515.
-
(2006)
J. Pharm. Biomed. Anal.
, vol.40
, pp. 509-515
-
-
Erny, G.L.1
Cifuentes, A.2
-
83
-
-
0022974867
-
Enantioselective analysis of chloroquine and desethylchloroquine after oral administration of racemic chloroquine
-
Ofori-Adjei, D.; Ericsson, O.; Lindström, B.; Hermansson, J.; Adjepon-Yamoah, K.; Sjöqvist, F. Enantioselective analysis of chloroquine and desethylchloroquine after oral administration of racemic chloroquine. Ther. Drug Monit., 1986, 8, 457-461.
-
(1986)
Ther. Drug Monit.
, vol.8
, pp. 457-461
-
-
Ofori-Adjei, D.1
Ericsson, O.2
Lindström, B.3
Hermansson, J.4
Adjepon-Yamoah, K.5
Sjöqvist, F.6
-
84
-
-
0025120977
-
Separation of chloroquine enantiomers by high-performance liquid chromatography
-
Ibrahim, K.E.; Fell, A.F. Separation of chloroquine enantiomers by high-performance liquid chromatography. J. Pharm. Biomed. Anal., 1990, 8, 449-452.
-
(1990)
J. Pharm. Biomed. Anal.
, vol.8
, pp. 449-452
-
-
Ibrahim, K.E.1
Fell, A.F.2
-
85
-
-
0026778434
-
1-acid glycoprotein chiral stationary phase: Evidence for a multiple-site chiral recognition mechanism
-
1-acid glycoprotein chiral stationary phase: evidence for a multiple-site chiral recognition mechanism. Chirality, 1992, 4, 30-35.
-
(1992)
Chirality
, vol.4
, pp. 30-35
-
-
Aubry, A.F.1
Gimenez, F.2
Farinotti, R.3
Wainer, I.W.4
-
86
-
-
0003070479
-
Tris(4-tbutylphenylcarbamate) s of cellulose and amylose as useful chiral stationary phases for chromatographic optical resolution
-
Okamoto, Y.; Hatano, K.; Aburatani, R.; Hatada, K. Tris(4- tbutylphenylcarbamate) s of cellulose and amylose as useful chiral stationary phases for chromatographic optical resolution. Chem. Lett., 1989, 715-718.
-
(1989)
Chem. Lett.
, pp. 715-718
-
-
Okamoto, Y.1
Hatano, K.2
Aburatani, R.3
Hatada, K.4
-
87
-
-
0032745915
-
Separation of enantiomers on anion exchangers modified with heparin in liquid chromatography
-
Safni Ito, N.; Takeuchi, T.; Miwa, T. Separation of enantiomers on anion exchangers modified with heparin in liquid chromatography. J. Chromatogr. A, 1999, 864, 25-30.
-
(1999)
J. Chromatogr. A
, vol.864
, pp. 25-30
-
-
Safni Ito, N.1
Takeuchi, T.2
Miwa, T.3
-
88
-
-
1842480646
-
Transforming chiral liquid chromatography methodologies into more sensitive liquid chromatography-electrospray ionization mass spectrometry without losing enantioselectivity
-
Desai, M.J.; Armstrong, D.W. Transforming chiral liquid chromatography methodologies into more sensitive liquid chromatography-electrospray ionization mass spectrometry without losing enantioselectivity. J. Chromatogr. A, 2004, 1035, 203-210.
-
(2004)
J. Chromatogr. A
, vol.1035
, pp. 203-210
-
-
Desai, M.J.1
Armstrong, D.W.2
-
90
-
-
54349088718
-
Enantioselective determination of chloroquine and its n-dealkylated metabolites in plasma using liquid- Phase microextraction and LC-MS
-
Magalhães, I.R.S.; Bonato, P.S. Enantioselective determination of chloroquine and its n-dealkylated metabolites in plasma using liquid- phase microextraction and LC-MS. J. Sep. Sci., 2008, 31, 3106-3116.
-
(2008)
J. Sep. Sci.
, vol.31
, pp. 3106-3116
-
-
Magalhães, I.R.S.1
Bonato, P.S.2
-
91
-
-
0024981327
-
Chiral separation of the optical isomers of the antimalarial drug halofantrine
-
Camilleri, P.; Dyke, C.; Hossner, F. Chiral separation of the optical isomers of the antimalarial drug halofantrine. J. Chromatogr., 1989, 477, 471-473.
-
(1989)
J. Chromatogr.
, vol.477
, pp. 471-473
-
-
Camilleri, P.1
Dyke, C.2
Hossner, F.3
-
92
-
-
0026647624
-
The determination of the enantiomers of halofantrine and monodesbutylhalofantrine in plasma and whole blood using sequential achiral/chiral high-performance liquid chromatography
-
Gimenez, F.; Aubry, A.F.; Farinotti, R.; Kirkland, K.; Wainer, I.W. The determination of the enantiomers of halofantrine and monodesbutylhalofantrine in plasma and whole blood using sequential achiral/chiral high-performance liquid chromatography. J. Pharm. Biomed. Anal., 1992, 10, 245-250.
-
(1992)
J. Pharm. Biomed. Anal.
, vol.10
, pp. 245-250
-
-
Gimenez, F.1
Aubry, A.F.2
Farinotti, R.3
Kirkland, K.4
Wainer, I.W.5
-
93
-
-
0028351604
-
Changes in chiral selectivity with temperature for an ovomucoid protein-based column
-
Kirkland, K.M.; McCombs, D.A. Changes in chiral selectivity with temperature for an ovomucoid protein-based column. J. Chromatogr. A, 1994, 666, 211-219.
-
(1994)
J. Chromatogr. A
, vol.666
, pp. 211-219
-
-
Kirkland, K.M.1
McCombs, D.A.2
-
94
-
-
0027233056
-
Direct determination of the enantiomers of halofantrine and its pharmacologically active metabolite N-desbutylhalofantrine by high-performance liquid chromatography
-
Terefe, H.; Blaschke, G. Direct determination of the enantiomers of halofantrine and its pharmacologically active metabolite N-desbutylhalofantrine by high-performance liquid chromatography. J. Chromatogr., 1993, 615, 347-351.
-
(1993)
J. Chromatogr.
, vol.615
, pp. 347-351
-
-
Terefe, H.1
Blaschke, G.2
-
95
-
-
0032493708
-
Chiral chromatographic method to determine the enantiomers of halofantrine and its main chiral desbutyl metabolite in erythrocytes
-
Gorichon, E.; Martin, C.; Na-Bangchang, K.; Karbwang, J.; Thuillier, A.; Farinotti, R.; Gimenez, F. Chiral chromatographic method to determine the enantiomers of halofantrine and its main chiral desbutyl metabolite in erythrocytes. J. Chromatogr. B, 1998, 712, 259-262.
-
(1998)
J. Chromatogr. B
, vol.712
, pp. 259-262
-
-
Gorichon, E.1
Martin, C.2
Na-Bangchang, K.3
Karbwang, J.4
Thuillier, A.5
Farinotti, R.6
Gimenez, F.7
-
96
-
-
0029100802
-
A liquid chromatographic assay for the stereospecific quantitative analysis of halofantrine in human plasma
-
Brocks, D.R.; Dennis, M.J.; Schaefer, W.H. A liquid chromatographic assay for the stereospecific quantitative analysis of halofantrine in human plasma. J. Pharm. Biomed. Anal., 1995, 13, 911-918.
-
(1995)
J. Pharm. Biomed. Anal.
, vol.13
, pp. 911-918
-
-
Brocks, D.R.1
Dennis, M.J.2
Schaefer, W.H.3
-
97
-
-
0035734480
-
A high-performance liquid chromatographic assay for the determination of desbutylhalofantrine enantiomers in rat plasma
-
Brocks, D.R. A high-performance liquid chromatographic assay for the determination of desbutylhalofantrine enantiomers in rat plasma. J. Pharm. Pharm. Sci., 2001, 4, 24-31.
-
(2001)
J. Pharm. Pharm. Sci.
, vol.4
, pp. 24-31
-
-
Brocks, D.R.1
-
99
-
-
0029962695
-
The roles of stereochemistry and partial areas in a parallel design study to assess the bioequivalence of two formulations of hydroxychloroquine: A drug with a very long half-life
-
Midha, K.K.; Hubbard, J.W.; Rawson, M.J.; McKay, G.; Schwede, R. The roles of stereochemistry and partial areas in a parallel design study to assess the bioequivalence of two formulations of hydroxychloroquine: a drug with a very long half-life. Eur. J. Pharm. Sci., 1996, 4, 283-292.
-
(1996)
Eur. J. Pharm. Sci.
, vol.4
, pp. 283-292
-
-
Midha, K.K.1
Hubbard, J.W.2
Rawson, M.J.3
McKay, G.4
Schwede, R.5
-
100
-
-
0026530930
-
Determination of hydroxychloroquine and its major metabolites in plasma using sequential achiral-chiral high-performance liquid chromatography
-
Iredale, J.; Wainer, I.W. Determination of hydroxychloroquine and its major metabolites in plasma using sequential achiral-chiral high-performance liquid chromatography. J. Chromatogr., 1992, 572, 253-258.
-
(1992)
J. Chromatogr.
, vol.572
, pp. 253-258
-
-
Iredale, J.1
Wainer, I.W.2
-
101
-
-
0027263894
-
Enantioselective determination of hydroxychloroquine and its major metabolites in urine and the observation of a reversal in the (+)/(-)-hydroxychloroquine ratio
-
Fieger, H.; Iredale, J.; Wainer, I.W. Enantioselective determination of hydroxychloroquine and its major metabolites in urine and the observation of a reversal in the (+)/(-)-hydroxychloroquine ratio. Chirality, 1992, 5, 65-70.
-
(1992)
Chirality
, vol.5
, pp. 65-70
-
-
Fieger, H.1
Iredale, J.2
Wainer, I.W.3
-
102
-
-
0027786843
-
Determination of the stereoisomers of hydroxychloroquine and its major metabolites in plasma and urine following a single oral administration of racemic hydroxychloroquine
-
Iredale, J.; Fieger, H.; Wainer, I.W. Determination of the stereoisomers of hydroxychloroquine and its major metabolites in plasma and urine following a single oral administration of racemic hydroxychloroquine. Semin. Arthritis Rheum., 1993, 23, 74-81.
-
(1993)
Semin. Arthritis Rheum.
, vol.23
, pp. 74-81
-
-
Iredale, J.1
Fieger, H.2
Wainer, I.W.3
-
103
-
-
0028501392
-
A HPLC method for the separation and quantification of the enantiomers of hydroxychloroquine and its three major metabolites
-
Wei, Y.; Nygard, G.A.; Khalil, S.K.W. A HPLC method for the separation and quantification of the enantiomers of hydroxychloroquine and its three major metabolites. J. Liq. Chromatogr. Relat. Technol., 1994, 17, 3479-3490.
-
(1994)
J. Liq. Chromatogr. Relat. Technol.
, vol.17
, pp. 3479-3490
-
-
Wei, Y.1
Nygard, G.A.2
Khalil, S.K.W.3
-
104
-
-
0026727697
-
Analytical and semipreparative high-performance liquid chromatographic separation and assay of hydroxychloroquine enantiomers
-
Brocks, D.R.; Pasutto, F.M.; Jamali, F. Analytical and semipreparative high-performance liquid chromatographic separation and assay of hydroxychloroquine enantiomers. J. Chromatogr. B, 1992, 581, 83-92.
-
(1992)
J. Chromatogr. B
, vol.581
, pp. 83-92
-
-
Brocks, D.R.1
Pasutto, F.M.2
Jamali, F.3
-
105
-
-
15744379951
-
Enantioselective analysis of the metabolites of hydroxychloroquine and application to an in vitro metabolic study
-
Cardoso, C.D.; Bonato, P.S. Enantioselective analysis of the metabolites of hydroxychloroquine and application to an in vitro metabolic study. J. Pharm. Biomed. Anal., 2005, 37, 703-708.
-
(2005)
J. Pharm. Biomed. Anal.
, vol.37
, pp. 703-708
-
-
Cardoso, C.D.1
Bonato, P.S.2
-
106
-
-
35649000447
-
Stereoselective determination of hydroxychloroquine and its major metabolites in human urine by solid-phase microextraction and HPLC
-
de Oliveira, A.R.M.; Bonato, P.S. Stereoselective determination of hydroxychloroquine and its major metabolites in human urine by solid-phase microextraction and HPLC. J. Sep. Sci., 2007, 30, 2351-2359.
-
(2007)
J. Sep. Sci.
, vol.30
, pp. 2351-2359
-
-
De Oliveira, A.R.M.1
Bonato, P.S.2
-
107
-
-
0025268795
-
Determination of the enantiomers of mefloquine in plasma and whole blood using a coupled achiral-chiral high-performance liquid chromatographic system
-
Gimenez, F.; Farinotti, R.; Thuillier, A.; Hazebroucq, G.; Wainer, I.W. Determination of the enantiomers of mefloquine in plasma and whole blood using a coupled achiral-chiral high-performance liquid chromatographic system. J. Chromatogr., 1990, 529, 339-346.
-
(1990)
J. Chromatogr.
, vol.529
, pp. 339-346
-
-
Gimenez, F.1
Farinotti, R.2
Thuillier, A.3
Hazebroucq, G.4
Wainer, I.W.5
-
108
-
-
0027257994
-
Improved column-switching liquid chromatographic method for the determination of the enantiomers of mefloquine
-
Gimenez, F.; Dumartin, C.; Wainer, I.W.; Farinotti, R. Improved column-switching liquid chromatographic method for the determination of the enantiomers of mefloquine. J. Chromatogr., 1993, 619, 161-166.
-
(1993)
J. Chromatogr.
, vol.619
, pp. 161-166
-
-
Gimenez, F.1
Dumartin, C.2
Wainer, I.W.3
Farinotti, R.4
-
109
-
-
0027382443
-
Enantioselective high-performance liquid chromatographic determination of (SR)- and (RS)-mefloquine in plasma using N-benzyloxycarbonyl-glycyl-L-proline as chiral counter ion
-
Bergqvist, Y.; Al Kabbani, J.; Pettersson, C.; Huynh, N.H. Enantioselective high-performance liquid chromatographic determination of (SR)- and (RS)-mefloquine in plasma using N-benzyloxycarbonyl-glycyl-L-proline as chiral counter ion. J. Chromatogr., 1993, 620, 217-224.
-
(1993)
J. Chromatogr.
, vol.620
, pp. 217-224
-
-
Bergqvist, Y.1
Al Kabbani, J.2
Pettersson, C.3
Huynh, N.H.4
-
110
-
-
0028351882
-
High-performance liquid chromatographic determination of (SR)- and (RS)-enantiomers of mefloquine in plasma and capillary blood sampled on paper after derivatization with (-)-l-(9-fluorenyl)ethyl chloroformate
-
Bergqvist, Y.; Doverskog, M.; Al Kabbani, J. High-performance liquid chromatographic determination of (SR)- and (RS)-enantiomers of mefloquine in plasma and capillary blood sampled on paper after derivatization with (-)-l-(9-fluorenyl)ethyl chloroformate. J. Chromatogr. B, 1994, 652, 73-81.
-
(1994)
J. Chromatogr. B
, vol.652
, pp. 73-81
-
-
Bergqvist, Y.1
Doverskog, M.2
Al Kabbani, J.3
-
111
-
-
0030690452
-
Stereospecific determination of mefloquine in biological fluids by high-performance liquid chromatography
-
Souri, E.; Farsam, H.; Jamali, F. Stereospecific determination of mefloquine in biological fluids by high-performance liquid chromatography. J. Chromatogr. B, 1997, 700, 215-222.
-
(1997)
J. Chromatogr. B
, vol.700
, pp. 215-222
-
-
Souri, E.1
Farsam, H.2
Jamali, F.3
-
112
-
-
0028344872
-
High-performance liquid chromatographic method for the enantioselective analysis of mefloquine in plasma and urine
-
Wallén, L.; Ericsson, Ö.; Wikström, I.; Hellgren, U. High-performance liquid chromatographic method for the enantioselective analysis of mefloquine in plasma and urine. J. Chromatogr. B, 1994, 655, 153-157.
-
(1994)
J. Chromatogr. B
, vol.655
, pp. 153-157
-
-
Wallén, L.1
Ericsson, Ö.2
Wikström, I.3
Hellgren, U.4
-
113
-
-
40849095908
-
Liquid-phase microextraction combined with high-performance liquid chromatography for the enantioselective analysis of mefloquine in plasma samples
-
Magalhães, I.R.S.; Bonato, P.S. Liquid-phase microextraction combined with high-performance liquid chromatography for the enantioselective analysis of mefloquine in plasma samples. J. Pharm. Biomed. Anal., 2008, 46, 929-936.
-
(2008)
J. Pharm. Biomed. Anal.
, vol.46
, pp. 929-936
-
-
Magalhães, I.R.S.1
Bonato, P.S.2
-
114
-
-
0026564939
-
A high-performance liquid chromatographic method for the quantitative enantioselective analysis of mefloquine stereoisomers
-
Qiu, Y.; Kitamura, S.; Guillory, J.K. A high-performance liquid chromatographic method for the quantitative enantioselective analysis of mefloquine stereoisomers. Pharm. Res., 1992, 9, 1640-1643.
-
(1992)
Pharm. Res.
, vol.9
, pp. 1640-1643
-
-
Qiu, Y.1
Kitamura, S.2
Guillory, J.K.3
-
115
-
-
66149091969
-
Two-step liquid-phase microextraction and high-performance liquid chromatography for the simultaneous analysis of the enantiomers of mefloquine and its main metabolite carboxymefloquine in plasma
-
Magalhães, I.R.S.; Bonato, P.S. Two-step liquid-phase microextraction and high-performance liquid chromatography for the simultaneous analysis of the enantiomers of mefloquine and its main metabolite carboxymefloquine in plasma. Anal. Bioanal. Chem., 2009, 393, 1805-1813.
-
(2009)
Anal. Bioanal. Chem.
, vol.393
, pp. 1805-1813
-
-
Magalhães, I.R.S.1
Bonato, P.S.2
-
116
-
-
0036377739
-
Enantiomeric resolution of drugs and metabolites in polysaccharide- And protein-based chiral stationary phases
-
Bonato, P.S.; Bortocan, R.; Gaitani, C.M.; Paias, F.O.; Ilha, M.H.; Lima, R.P. Enantiomeric resolution of drugs and metabolites in polysaccharide- and protein-based chiral stationary phases. J. Braz. Chem. Soc., 2002, 13, 190-199.
-
(2002)
J. Braz. Chem. Soc.
, vol.13
, pp. 190-199
-
-
Bonato, P.S.1
Bortocan, R.2
Gaitani, C.M.3
Paias, F.O.4
Ilha, M.H.5
Lima, R.P.6
-
117
-
-
0032076469
-
Enantiomer separation of amino compounds by a novel chiral stationary phase derived from crown ether
-
Machida, Y.; Nishi, H.; Nakamura, K.; Nakai, H.; Sato, T. Enantiomer separation of amino compounds by a novel chiral stationary phase derived from crown ether. J. Chromatogr. A, 1998, 805, 85-92.
-
(1998)
J. Chromatogr. A
, vol.805
, pp. 85-92
-
-
Machida, Y.1
Nishi, H.2
Nakamura, K.3
Nakai, H.4
Sato, T.5
-
118
-
-
0031697228
-
Chiral separations of selected pharmaceuticals on avidin column
-
Haque, A.; Stewart, J.T. Chiral separations of selected pharmaceuticals on avidin column. J. Liq. Chromatogry Relat. Technol., 1998, 21, 2675-2687.
-
(1998)
J. Liq. Chromatogry Relat. Technol.
, vol.21
, pp. 2675-2687
-
-
Haque, A.1
Stewart, J.T.2
-
119
-
-
0029088662
-
Quantification of the individual enantiomer plasma concentrations of the candidate antimalarial agent N4-[2,6 -dimethoxy-4-methyl-5-[(3-trifluoromethyl) phenoxy]-8-quinolinyl]-l,4-pentanediamine (WR238,605)
-
Karle, J.M.; Olmeda, R.; Freeman, S.G.; Schroeder, A.C. Quantification of the individual enantiomer plasma concentrations of the candidate antimalarial agent N4-[2,6 -dimethoxy-4-methyl-5-[(3-trifluoromethyl)phenoxy]-8-quinolinyl]- l,4-pentanediamine (WR238,605). J. Chromatogr. B, 1995, 670, 251-257.
-
(1995)
J. Chromatogr. B
, vol.670
, pp. 251-257
-
-
Karle, J.M.1
Olmeda, R.2
Freeman, S.G.3
Schroeder, A.C.4
-
120
-
-
33646360184
-
Enantioselective LC/MS method for the determination of an antimalarial agent Fenozan B07 in dog plasma
-
Maraschiello, C.; Vilageliu, J.; Dorronsoro, I.; Martinez, A.; Floriano, F.; Gómez-Acebo, E. Enantioselective LC/MS method for the determination of an antimalarial agent Fenozan B07 in dog plasma. Chirality, 2006, 18, 297-305.
-
(2006)
Chirality
, vol.18
, pp. 297-305
-
-
Maraschiello, C.1
Vilageliu, J.2
Dorronsoro, I.3
Martinez, A.4
Floriano, F.5
Gómez-Acebo, E.6
-
121
-
-
0038573965
-
Capillary electrophoresis - A high performance analytical separation technique
-
Wätzig, H.; Günter, S. Capillary electrophoresis - a high performance analytical separation technique. Clin. Chem. Lab. Med., 2003, 41, 724-738.
-
(2003)
Clin. Chem. Lab. Med.
, vol.41
, pp. 724-738
-
-
Wätzig, H.1
Günter, S.2
-
122
-
-
45249120173
-
Capillary electrophoresis in bioanalysis
-
Kostal, V.; Katzenmeyer, J.; Arriaga, E.A. Capillary electrophoresis in bioanalysis. Anal. Chem., 2008, 80, 4533-4550.
-
(2008)
Anal. Chem.
, vol.80
, pp. 4533-4550
-
-
Kostal, V.1
Katzenmeyer, J.2
Arriaga, E.A.3
-
123
-
-
0034647108
-
Enantioselective determination of drugs in body fluids by capillary electrophoresis
-
Zaugg, S.; Thormann, W. Enantioselective determination of drugs in body fluids by capillary electrophoresis. J. Chromatogr. A, 2000, 875, 27-41.
-
(2000)
J. Chromatogr. A
, vol.875
, pp. 27-41
-
-
Zaugg, S.1
Thormann, W.2
-
124
-
-
50049127805
-
Chiral separation by capillary electromigration techniques
-
Gübitz, G.; Schmid, M.G. Chiral separation by capillary electromigration techniques. J. Chromatogr. A, 2008, 1204, 140-156.
-
(2008)
J. Chromatogr. A
, vol.1204
, pp. 140-156
-
-
Gübitz, G.1
Schmid, M.G.2
-
125
-
-
0034646843
-
Enantiomer separation of chiral pharmaceuticals by capillary electrochromatography
-
Wistuba, D.; Schurig, V. Enantiomer separation of chiral pharmaceuticals by capillary electrochromatography. J. Chromatogr. A, 2000, 875, 255-276.
-
(2000)
J. Chromatogr. A
, vol.875
, pp. 255-276
-
-
Wistuba, D.1
Schurig, V.2
-
126
-
-
33846619228
-
Nonaqueous capillary electrophoresis in pharmaceutical analysis
-
Geiser, L.; Veuthey, J.L. Nonaqueous capillary electrophoresis in pharmaceutical analysis. Electrophoresis, 2007, 28, 45-57.
-
(2007)
Electrophoresis
, vol.28
, pp. 45-57
-
-
Geiser, L.1
Veuthey, J.L.2
-
127
-
-
0037067386
-
Colominic acid: A novel chiral selector for capillary electrophoresis of basic drugs
-
Du, Y.; Taga, A.; Suzuki, S.; Liu, W.; Honda, S. Colominic acid: a novel chiral selector for capillary electrophoresis of basic drugs. J. Chromatogr. A, 2002, 962, 221-231.
-
(2002)
J. Chromatogr. A
, vol.962
, pp. 221-231
-
-
Du, Y.1
Taga, A.2
Suzuki, S.3
Liu, W.4
Honda, S.5
-
128
-
-
0037154653
-
Effect of structure modification of chondroitin sulfate C on its enantioselectivity to basic drugs in capillary electrophoresis
-
Du, Y.; Taga, A.; Suzuki, S.; Liu, W.; Honda, S. Effect of structure modification of chondroitin sulfate C on its enantioselectivity to basic drugs in capillary electrophoresis. J. Chromatogr. A, 2002, 947, 287-299.
-
(2002)
J. Chromatogr. A
, vol.947
, pp. 287-299
-
-
Du, Y.1
Taga, A.2
Suzuki, S.3
Liu, W.4
Honda, S.5
-
129
-
-
0031858224
-
Dermatan sulfate as useful chiral selector in capillary electrophoresis
-
Gotti, R.; Cavrini, V.; Andrisano, V.; Mascellani, G. Dermatan sulfate as useful chiral selector in capillary electrophoresis. J. Chromatogr. A, 1998, 805, 205-211.
-
(1998)
J. Chromatogr. A
, vol.805
, pp. 205-211
-
-
Gotti, R.1
Cavrini, V.2
Andrisano, V.3
Mascellani, G.4
-
130
-
-
0029009487
-
Chiral separations using heparin and dextran sulfate in capillary zone electrophoresis
-
Agyei, N.M.; Gahm, K.H.; Stalcup, A.M. Chiral separations using heparin and dextran sulfate in capillary zone electrophoresis. Anal. Chim. Acta, 1995, 307, 185-191.
-
(1995)
Anal. Chim. Acta
, vol.307
, pp. 185-191
-
-
Agyei, N.M.1
Gahm, K.H.2
Stalcup, A.M.3
-
131
-
-
0033045601
-
Semisynthetic chondroitins as chiral buffer additives in capillary electrophoresis
-
Gotti, R.; Cavrini, V.; Andrisano, V.; Mascellani, G. Semisynthetic chondroitins as chiral buffer additives in capillary electrophoresis. J. Chromatogr. A, 1999, 845, 247-256.
-
(1999)
J. Chromatogr. A
, vol.845
, pp. 247-256
-
-
Gotti, R.1
Cavrini, V.2
Andrisano, V.3
Mascellani, G.4
-
132
-
-
0028075491
-
Heparin: A chiral mobile-phase additive for capillary zone electrophoresis
-
Stalcup, A.M.; Agyei, N.M. Heparin: a chiral mobile-phase additive for capillary zone electrophoresis. Anal. Chem., 1994, 66, 3054-3059.
-
(1994)
Anal. Chem.
, vol.66
, pp. 3054-3059
-
-
Stalcup, A.M.1
Agyei, N.M.2
-
133
-
-
0030200906
-
Chiral separation of chloroquine using heparin as a chiral selector in high-performance liquid chromatography
-
Stalcup, A.M.; Gahm, K.H.; Baldueza, M. Chiral separation of chloroquine using heparin as a chiral selector in high-performance liquid chromatography. Anal. Chem., 1996, 68, 2248-2250.
-
(1996)
Anal. Chem.
, vol.68
, pp. 2248-2250
-
-
Stalcup, A.M.1
Gahm, K.H.2
Baldueza, M.3
-
134
-
-
0032832297
-
Chiral selectors from fruit: Application of citrus pectins to enantiomer separations in capillary electrophoresis
-
Phinney, K.W.; Jinadu, L.A.; Sander, L.C. Chiral selectors from fruit: application of citrus pectins to enantiomer separations in capillary electrophoresis. J. Chromatogr. A, 1999, 857, 285-293.
-
(1999)
J. Chromatogr. A
, vol.857
, pp. 285-293
-
-
Phinney, K.W.1
Jinadu, L.A.2
Sander, L.C.3
-
135
-
-
0346504258
-
Comparative enantioseparations with native β-cyclodextrin, randomly acetylated β-cyclodextrin and heptakis-(2,3-di-O-acetyl)-β- cyclodextrin in capillary electrophoresis
-
Chankvetadze, B.; Lomsadze, K.; Burjanadze, N.; Breitkreutz, J.; Pintore, G.; Chessa, M.; Bergander, K.; Blaschke, G. Comparative enantioseparations with native β-cyclodextrin, randomly acetylated β-cyclodextrin and heptakis-(2,3-di-O-acetyl)-β-cyclodextrin in capillary electrophoresis. Electrophoresis, 2003, 24, 1083-1091.
-
(2003)
Electrophoresis
, vol.24
, pp. 1083-1091
-
-
Chankvetadze, B.1
Lomsadze, K.2
Burjanadze, N.3
Breitkreutz, J.4
Pintore, G.5
Chessa, M.6
Bergander, K.7
Blaschke, G.8
-
136
-
-
0031854646
-
Chiral separation of chloroquine and pemoline by capillary zone electrophoresis with sulfobutyl ether β-cyclodextrin as buffer additive
-
Dong, Y.; Huang, A.; Sun, Y.; Sun, Z. Chiral separation of chloroquine and pemoline by capillary zone electrophoresis with sulfobutyl ether β-cyclodextrin as buffer additive. Chromatographia, 1998, 48, 310-313.
-
(1998)
Chromatographia
, vol.48
, pp. 310-313
-
-
Dong, Y.1
Huang, A.2
Sun, Y.3
Sun, Z.4
-
137
-
-
0032562457
-
Comparison of chiral recognition capabilities of cyclodextrins for the separation of basic drugs in capillary zone electrophoresis
-
Jin, L.J.; Li, S.F.Y. Comparison of chiral recognition capabilities of cyclodextrins for the separation of basic drugs in capillary zone electrophoresis. J. Chromatogr. B, 1998, 708, 257-266.
-
(1998)
J. Chromatogr. B
, vol.708
, pp. 257-266
-
-
Jin, L.J.1
Li, S.F.Y.2
-
138
-
-
26844499908
-
Enantioseparation of some clinically used drugs by capillary electrophoresis using sulfated β-cyclodextrin as a chiral selector
-
Yang, G.S.; Chen, D.M.; Yang, Y.; Tang, B.; Gao, J.J.; Aboul-Enein, H.Y.; Koppenhoefer, B. Enantioseparation of some clinically used drugs by capillary electrophoresis using sulfated β-cyclodextrin as a chiral selector. Chromatographia, 2005, 62, 441-445.
-
(2005)
Chromatographia
, vol.62
, pp. 441-445
-
-
Yang, G.S.1
Chen, D.M.2
Yang, Y.3
Tang, B.4
Gao, J.J.5
Aboul-Enein, H.Y.6
Koppenhoefer, B.7
-
139
-
-
0037212812
-
Capillary electrophoretic separation of drug enantiomers in human serum
-
Taga, A.; Du, Y.; Suzuki, S.; Honda, S. Capillary electrophoretic separation of drug enantiomers in human serum. J. Pharm. Biomed. Anal., 2003, 30, 1587-1593.
-
(2003)
J. Pharm. Biomed. Anal.
, vol.30
, pp. 1587-1593
-
-
Taga, A.1
Du, Y.2
Suzuki, S.3
Honda, S.4
-
140
-
-
0034308937
-
Enantioselective assay of chloroquine and its main metabolite deethyl chloroquine in human plasma by capillary electrophoresis
-
Müller, D.; Blaschke, G. Enantioselective assay of chloroquine and its main metabolite deethyl chloroquine in human plasma by capillary electrophoresis. J. Chromatogr. Sci., 2000, 38, 435-440.
-
(2000)
J. Chromatogr. Sci.
, vol.38
, pp. 435-440
-
-
Müller, D.1
Blaschke, G.2
-
141
-
-
33645468790
-
Capillary electrophoretic chiral separation of hydroxychloroquine and its metabolites in the microsomal fraction of liver homogenates
-
Cardoso, C.D.; Jabor, V.A.P.; Bonato, P.S. Capillary electrophoretic chiral separation of hydroxychloroquine and its metabolites in the microsomal fraction of liver homogenates. Electrophoresis, 2006, 27, 1248-1254.
-
(2006)
Electrophoresis
, vol.27
, pp. 1248-1254
-
-
Cardoso, C.D.1
Jabor, V.A.P.2
Bonato, P.S.3
-
142
-
-
34247155188
-
Stereoselective determination of hydroxychloroquine and its metabolites in human urine by liquid-phase microextraction and CE
-
de Oliveira, A.R.M.; Cardoso, C.D.; Bonato, P.S. Stereoselective determination of hydroxychloroquine and its metabolites in human urine by liquid-phase microextraction and CE. Electrophoresis, 2007, 28, 1081-1091.
-
(2007)
Electrophoresis
, vol.28
, pp. 1081-1091
-
-
De Oliveira, A.R.M.1
Cardoso, C.D.2
Bonato, P.S.3
-
143
-
-
0030595274
-
Use of cyclodextrins in the capillary electrophoretic separation of erythro- And threo-mefloquine enantiomers
-
Fanali, S.; Camera, E. Use of cyclodextrins in the capillary electrophoretic separation of erythro- and threo-mefloquine enantiomers. J. Chromatogr. A, 1996, 745, 17-23.
-
(1996)
J. Chromatogr. A
, vol.745
, pp. 17-23
-
-
Fanali, S.1
Camera, E.2
-
144
-
-
0030904628
-
Separation of enantiomers of drugs by capillary electrophoresis. Part 4: Hydroxypropyl-gammacyclodextrin as chiral solvating agent
-
Koppenhoefer, B.; Epperlein, U.; Xiaofeng, Z.; Bingcheng, L. Separation of enantiomers of drugs by capillary electrophoresis. Part 4: Hydroxypropyl-gammacyclodextrin as chiral solvating agent. Electrophoresis, 1997, 18, 924-930.
-
(1997)
Electrophoresis
, vol.18
, pp. 924-930
-
-
Koppenhoefer, B.1
Epperlein, U.2
Xiaofeng, Z.3
Bingcheng, L.4
-
145
-
-
0031928080
-
Separation of enantiomers of drugs by capillary electrophoresis, part 7: Gammacyclodextrin as chiral solvating agent
-
Koppenhoefer, B.; Epperlein, U.; Jakob, A.; Wuerthner, S.; Xiaofeng, Z.; Bingcheng, L. Separation of enantiomers of drugs by capillary electrophoresis, part 7: Gammacyclodextrin as chiral solvating agent. Chirality, 1998, 10, 548-554.
-
(1998)
Chirality
, vol.10
, pp. 548-554
-
-
Koppenhoefer, B.1
Epperlein, U.2
Jakob, A.3
Wuerthner, S.4
Xiaofeng, Z.5
Bingcheng, L.6
-
146
-
-
0032498123
-
Separation of enantiomers of drugs by capillary electrophoresis V. Hydroxypropyl-α-cyclodextrin as chiral solvating agent
-
Koppenhoefer, B.; Epperlein, U.; Schlunk, R.; Zhu, Y.; Bingcheng, L. Separation of enantiomers of drugs by capillary electrophoresis V. Hydroxypropyl-α-cyclodextrin as chiral solvating agent. J. Chromatogr. A, 1998, 793, 153-164.
-
(1998)
J. Chromatogr. A
, vol.793
, pp. 153-164
-
-
Koppenhoefer, B.1
Epperlein, U.2
Schlunk, R.3
Zhu, Y.4
Bingcheng, L.5
-
147
-
-
0036744618
-
Comparative enantioseparations with native β-cyclodextrin and heptakis-(2-O-methyl-3,6-di-O-sulfo)-β- Cyclodextrin in capillary electrophoresis
-
Chankvetadze, B.; Burjanadze, N.; Maynard, D.M.; Bergander, K.; Bergenthal, D.; Blaschke, G. Comparative enantioseparations with native β-cyclodextrin and heptakis-(2-O-methyl-3,6-di-O-sulfo)-β- cyclodextrin in capillary electrophoresis. Electrophoresis, 2002, 23, 3027-3034.
-
(2002)
Electrophoresis
, vol.23
, pp. 3027-3034
-
-
Chankvetadze, B.1
Burjanadze, N.2
Maynard, D.M.3
Bergander, K.4
Bergenthal, D.5
Blaschke, G.6
-
148
-
-
0037464414
-
Enantioseparation of erythro-mefloquine and its analogues in capillary electrophoresis
-
Chankvetadze, B.; Burjanadze, N.; Blaschke, G. Enantioseparation of erythro-mefloquine and its analogues in capillary electrophoresis. J. Pharm. Biomed. Anal., 2003, 32, 41-49.
-
(2003)
J. Pharm. Biomed. Anal.
, vol.32
, pp. 41-49
-
-
Chankvetadze, B.1
Burjanadze, N.2
Blaschke, G.3
-
149
-
-
33751296722
-
δ-Cyclodextrin as novel chiral probe for enantiomeric separation by electromigration methods
-
Wistuba, D.; Bogdanski, A.; Larsen, K.L.; Schurig, V. δ-Cyclodextrin as novel chiral probe for enantiomeric separation by electromigration methods. Electrophoresis, 2006, 27, 4359-4363.
-
(2006)
Electrophoresis
, vol.27
, pp. 4359-4363
-
-
Wistuba, D.1
Bogdanski, A.2
Larsen, K.L.3
Schurig, V.4
-
150
-
-
38949106144
-
Highlighting the role of the hydroxyl position on the alkyl spacer of hydroxypropyl-β-cyclodextrin for enantioseparation in capillary electrophoresis
-
Jiang, Z.; Thorogate, R.; Smith, N.W. Highlighting the role of the hydroxyl position on the alkyl spacer of hydroxypropyl-β-cyclodextrin for enantioseparation in capillary electrophoresis. J. Sep. Sci., 2008, 31, 177-187.
-
(2008)
J. Sep. Sci.
, vol.31
, pp. 177-187
-
-
Jiang, Z.1
Thorogate, R.2
Smith, N.W.3
-
151
-
-
0035104429
-
Use of vancomycin silica stationary phase in packed capillary electrochromatography I. Enantiomer separation of basic compounds
-
Desiderio, C.; Aturki, Z.; Fanali, S. Use of vancomycin silica stationary phase in packed capillary electrochromatography I. Enantiomer separation of basic compounds. Electrophoresis, 2001, 22, 535-543.
-
(2001)
Electrophoresis
, vol.22
, pp. 535-543
-
-
Desiderio, C.1
Aturki, Z.2
Fanali, S.3
-
152
-
-
0034790031
-
Development of stereoselective nonaqueous capillary electrophoresis system for the resolution of cationic and amphoteric analytes
-
Zarbl, E.; Lämmerhofer, M.; Franco, P.; Petracs, M.; Lindner, W. Development of stereoselective nonaqueous capillary electrophoresis system for the resolution of cationic and amphoteric analytes. Electrophoresis, 2001, 22, 3297-3307.
-
(2001)
Electrophoresis
, vol.22
, pp. 3297-3307
-
-
Zarbl, E.1
Lämmerhofer, M.2
Franco, P.3
Petracs, M.4
Lindner, W.5
-
153
-
-
0036198663
-
Low-molecular-weight chiral cation exchangers: Novel chiral stationary phases and their application for enantioseparation of chiral bases by nonaqueous capillary electrochromatography
-
Tobler, E.; Lämmerhofer, M.; Wuggenig, F.; Hammerschmidt, F.; Lindner, W. Low-molecular-weight chiral cation exchangers: novel chiral stationary phases and their application for enantioseparation of chiral bases by nonaqueous capillary electrochromatography. Electrophoresis, 2002, 23, 462-476.
-
(2002)
Electrophoresis
, vol.23
, pp. 462-476
-
-
Tobler, E.1
Lämmerhofer, M.2
Wuggenig, F.3
Hammerschmidt, F.4
Lindner, W.5
-
154
-
-
0036924631
-
Strong versus weak chiral cation exchangers: Comparative evaluation for enantiomer separation of chiral bases by non-aqueous CEC
-
Zarbl, E.; Lämmerhofer, M.; Woschek, A.; Hammerschmidt, F.; Parenti, C.; Cannazza, G.; Lindner, W. Strong versus weak chiral cation exchangers: comparative evaluation for enantiomer separation of chiral bases by non-aqueous CEC. Electrophoresis, 2002, 25, 1269-1283.
-
(2002)
Electrophoresis
, vol.25
, pp. 1269-1283
-
-
Zarbl, E.1
Lämmerhofer, M.2
Woschek, A.3
Hammerschmidt, F.4
Parenti, C.5
Cannazza, G.6
Lindner, W.7
-
155
-
-
0029683521
-
Dextran and dextrin as chiral selectors in capillary zone electrophoresis
-
Nishi, H.; Izumoto, S.; Nakamura, K.; Nakai, H.; Sato, T. Dextran and dextrin as chiral selectors in capillary zone electrophoresis. Chromatographia, 1996, 42, 617-630.
-
(1996)
Chromatographia
, vol.42
, pp. 617-630
-
-
Nishi, H.1
Izumoto, S.2
Nakamura, K.3
Nakai, H.4
Sato, T.5
-
156
-
-
0037080855
-
Enantiomer separation by capillary electrophoresis utilizing carboxymethyl derivatives of polysaccharides as chiral selectors
-
Nishi, H.; Kuwahara, Y. Enantiomer separation by capillary electrophoresis utilizing carboxymethyl derivatives of polysaccharides as chiral selectors. J. Pharm. Biomed. Anal., 2002, 27, 577-585.
-
(2002)
J. Pharm. Biomed. Anal.
, vol.27
, pp. 577-585
-
-
Nishi, H.1
Kuwahara, Y.2
-
157
-
-
0028941625
-
Partial separation zone technique for the separation of enantiomers by affinity electrokinetic chromatography with proteins as chiral pseudo-stationary phases
-
Tanaka, Y.; Terabe, S. Partial separation zone technique for the separation of enantiomers by affinity electrokinetic chromatography with proteins as chiral pseudo-stationary phases. J. Chromatogr. A, 1995, 694, 277-284.
-
(1995)
J. Chromatogr. A
, vol.694
, pp. 277-284
-
-
Tanaka, Y.1
Terabe, S.2
-
158
-
-
0031048403
-
1-acid glycoprotein as chiral selector
-
1-acid glycoprotein as chiral selector. Chromatographia, 1997, 44, 119-128.
-
(1997)
Chromatographia
, vol.44
, pp. 119-128
-
-
Tanaka, Y.1
Terabe, S.2
-
159
-
-
0031550289
-
Separation of enantiomers and isomers of amino compounds by capillary electrophoresis and high-performance liquid chromatography utilizing crown ethers
-
Nishi, H.; Nakamura, K.; Nakai, H.; Sato, T. Separation of enantiomers and isomers of amino compounds by capillary electrophoresis and high-performance liquid chromatography utilizing crown ethers. J. Chromatogr. A, 1997, 757, 225-235.
-
(1997)
J. Chromatogr. A
, vol.757
, pp. 225-235
-
-
Nishi, H.1
Nakamura, K.2
Nakai, H.3
Sato, T.4
-
160
-
-
4544280151
-
Enantioselective analysis of primaquine and its metabolite carboxyprimaquine by capillary electrophoresis
-
Bortocan, R.; Bonato, P.S. Enantioselective analysis of primaquine and its metabolite carboxyprimaquine by capillary electrophoresis. Electrophoresis, 2004, 25, 2848-2853.
-
(2004)
Electrophoresis
, vol.25
, pp. 2848-2853
-
-
Bortocan, R.1
Bonato, P.S.2
-
161
-
-
0027981258
-
Chiral separation of drugs by capillary electrophoresis using β-cyclodextrin polymer
-
Nishi, H.; Nakamura, K.; Nakai, H.; Sato, T. Chiral separation of drugs by capillary electrophoresis using β-cyclodextrin polymer. J. Chromatogr. A, 1994, 678, 333-342.
-
(1994)
J. Chromatogr. A
, vol.678
, pp. 333-342
-
-
Nishi, H.1
Nakamura, K.2
Nakai, H.3
Sato, T.4
-
162
-
-
0347137317
-
Separation of neutral and basic enantiomers by cyclodextrin electrokinetic chromatography using anionic cyclodextrin derivatives as chiral pseudo-stationary phases
-
Tanaka, Y.; Yanagawa, M.; Terabe, S. Separation of neutral and basic enantiomers by cyclodextrin electrokinetic chromatography using anionic cyclodextrin derivatives as chiral pseudo-stationary phases. J. High Resolut. Chromatogr., 1996, 19, 421-433.
-
(1996)
J. High Resolut. Chromatogr.
, vol.19
, pp. 421-433
-
-
Tanaka, Y.1
Yanagawa, M.2
Terabe, S.3
-
163
-
-
0028057538
-
Chiral separation of drugs using cyclodextrins in capillary zone electrophoresis
-
Nishi, H.; Kokusenya, Y.; Miyamoto, T.; Sato, T. Chiral separation of drugs using cyclodextrins in capillary zone electrophoresis. J. Chromatogr. A, 1994, 659, 449-457.
-
(1994)
J. Chromatogr. A
, vol.659
, pp. 449-457
-
-
Nishi, H.1
Kokusenya, Y.2
Miyamoto, T.3
Sato, T.4
-
164
-
-
45849095664
-
Development of a capillary electrophoresis method for the enantioselective estimation of primaquine in pharmaceutical formulations
-
Elbashir, A.A.; Saad, B.; Ali, A.S.M.; Saleh, M.I. Development of a capillary electrophoresis method for the enantioselective estimation of primaquine in pharmaceutical formulations. J. AOAC Int., 2008, 91, 536-541.
-
(2008)
J. AOAC Int.
, vol.91
, pp. 536-541
-
-
Elbashir, A.A.1
Saad, B.2
Ali, A.S.M.3
Saleh, M.I.4
-
165
-
-
65249146146
-
Enantioselective analysis of primaquine and its impurity quinocide by capillary electrophoresis
-
Elbashir, A.A.; Saad, B.; Ali, A.S.M.; Saleh, M.I.; Aboul-Enein, H.Y. Enantioselective analysis of primaquine and its impurity quinocide by capillary electrophoresis. Biomed. Chromatogr., 2009, 23, 295-301.
-
(2009)
Biomed. Chromatogr.
, vol.23
, pp. 295-301
-
-
Elbashir, A.A.1
Saad, B.2
Ali, A.S.M.3
Saleh, M.I.4
Aboul-Enein, H.Y.5
-
166
-
-
0036001456
-
Enantiomeric separation of primaquine, an antimalarial drug, by cyclodextrin-modified micellar electrokinetic capillary chromatography
-
Zhang, C.; Zhu, C.; Lin, X.; Gao, F.; Wei, Y. Enantiomeric separation of primaquine, an antimalarial drug, by cyclodextrin-modified micellar electrokinetic capillary chromatography. Anal. Sci., 2002, 18, 595-597.
-
(2002)
Anal. Sci.
, vol.18
, pp. 595-597
-
-
Zhang, C.1
Zhu, C.2
Lin, X.3
Gao, F.4
Wei, Y.5
-
167
-
-
39749092605
-
Liquid-phase microextraction with porous hollow fibers, a miniaturized and highly flexible format for liquid-liquid extraction
-
Pedersen-Bjergaard, S.; Rasmussen, K.E. Liquid-phase microextraction with porous hollow fibers, a miniaturized and highly flexible format for liquid-liquid extraction. J. Chromatogr. A, 2008, 1184, 132-142.
-
(2008)
J. Chromatogr. A
, vol.1184
, pp. 132-142
-
-
Pedersen-Bjergaard, S.1
Rasmussen, K.E.2
-
168
-
-
48949092425
-
Environmental and bioanalytical applications of hollow fiber membrane liquid-phase microextraction: A review
-
Lee, J.; Lee, H.K.; Rasmussen, K.E.; Pedersen-Bjergaard, S. Environmental and bioanalytical applications of hollow fiber membrane liquid-phase microextraction: a review. Anal. Chim. Acta, 2008, 624, 253-268.
-
(2008)
Anal. Chim. Acta
, vol.624
, pp. 253-268
-
-
Lee, J.1
Lee, H.K.2
Rasmussen, K.E.3
Pedersen-Bjergaard, S.4
-
169
-
-
34547294240
-
Application of solid-phase microextraction in analytical toxicology
-
Pragst, F. Application of solid-phase microextraction in analytical toxicology. Anal. Bioanal. Chem., 2007, 388, 1393-1414.
-
(2007)
Anal. Bioanal. Chem.
, vol.388
, pp. 1393-1414
-
-
Pragst, F.1
-
170
-
-
20544463335
-
Recent advances in solid-phase microextraction and related techniques for pharmaceutical and biomedical analysis
-
Kataoka, H. Recent advances in solid-phase microextraction and related techniques for pharmaceutical and biomedical analysis. Curr. Pharm. Anal., 2005, 1, 65-84.
-
(2005)
Curr. Pharm. Anal.
, vol.1
, pp. 65-84
-
-
Kataoka, H.1
|