-
1
-
-
0026595679
-
Halofantrine; a review of its anti-malarial activity, pharmacokinetic properties and therapeutic potential
-
Bryson HM and Goa KL. Halofantrine; a review of its anti-malarial activity, pharmacokinetic properties and therapeutic potential. Drugs 1992; 43: 236-258.
-
(1992)
Drugs
, vol.43
, pp. 236-258
-
-
Bryson, H.M.1
Goa, K.L.2
-
2
-
-
0026583261
-
In vitro activity of the enantiomers of mefloquine, halofantrine and enpiroline against Plasmodium falciparum
-
Basco LK, Gillotin C, Gimenez F, Farinotti R and Le Bras J. In vitro activity of the enantiomers of mefloquine, halofantrine and enpiroline against Plasmodium falciparum. Br J Clin Pharmacol 1992; 33: 517-520.
-
(1992)
Br J Clin Pharmacol
, vol.33
, pp. 517-520
-
-
Basco, L.K.1
Gillotin, C.2
Gimenez, F.3
Farinotti, R.4
Le Bras, J.5
-
3
-
-
0027267401
-
Plasmodium faldparum: Role of absolute stereochemistry in the antimalarial activity of synthetic amino alcohol antimalarial drugs
-
Karle JM, Olmeda R, Gerena L and Milhous WK. Plasmodium faldparum: Role of absolute stereochemistry in the antimalarial activity of synthetic amino alcohol antimalarial drugs. Exp Parasitol 1993; 76: 345-351.
-
(1993)
Exp Parasitol
, vol.76
, pp. 345-351
-
-
Karle, J.M.1
Olmeda, R.2
Gerena, L.3
Milhous, W.K.4
-
4
-
-
0026647624
-
The determination of the enantiomers of halofantrine and monodesbutylhalofantrine in plasma and whole blood using sequential achiral/chiral high performance liquid chromatography
-
Gimenez F, Aubry AF, Farinotti R, Kirkland R and Wainer IW. The determination of the enantiomers of halofantrine and monodesbutylhalofantrine in plasma and whole blood using sequential achiral/chiral high performance liquid chromatography. J Chramatogr 1992; 10: 245-250.
-
(1992)
J Chramatogr
, vol.10
, pp. 245-250
-
-
Gimenez, F.1
Aubry, A.F.2
Farinotti, R.3
Kirkland, R.4
Wainer, I.W.5
-
5
-
-
0029100802
-
A liquid chromatographic assay for the stereospecific quantitative analysis of halofantrine in human plasma
-
Brocks DR, Dennis MJ and Schaefer WH. A liquid chromatographic assay for the stereospecific quantitative analysis of halofantrine in human plasma. J Pharm Biomed Anal 1995; 13: 911-918.
-
(1995)
J Pharm Biomed Anal
, vol.13
, pp. 911-918
-
-
Brocks, D.R.1
Dennis, M.J.2
Schaefer, W.H.3
-
6
-
-
0028001131
-
Plasma concentrations of the enantiomers of halofantrine and its main metabolite in malaria patients
-
Gimenez F, Gillotin C, Basco LK, Bouchaud O, Aubry AF, Wainer IW, Le Bras J and Farinotti R. Plasma concentrations of the enantiomers of halofantrine and its main metabolite in malaria patients. Eur J Clin Pharmacol 1994; 46: 561-562.
-
(1994)
Eur J Clin Pharmacol
, vol.46
, pp. 561-562
-
-
Gimenez, F.1
Gillotin, C.2
Basco, L.K.3
Bouchaud, O.4
Aubry, A.F.5
Wainer, I.W.6
Le Bras, J.7
Farinotti, R.8
-
7
-
-
0028048876
-
Clinical pharmacokinetics of halofantrine
-
Karbwang J and Bangchang KN. Clinical pharmacokinetics of halofantrine. Clin Pharmacokinet 1994; 27: 104-119.
-
(1994)
Clin Pharmacokinet
, vol.27
, pp. 104-119
-
-
Karbwang, J.1
Bangchang, K.N.2
-
8
-
-
0024335624
-
Pharmacokinetics of halofantrine in man: Effects of food and dose size
-
Milton KA, Edwards G, Ward SA, Orme MLE and Breckenridge AM. Pharmacokinetics of halofantrine in man: effects of food and dose size. Br J Clin Pharmacol 1989; 28: 71-77.
-
(1989)
Br J Clin Pharmacol
, vol.28
, pp. 71-77
-
-
Milton, K.A.1
Edwards, G.2
Ward, S.A.3
Orme, M.L.E.4
Breckenridge, A.M.5
-
9
-
-
0029996464
-
A physiochemical basis for the effect of food on the absolute bioavailability of halofantrine
-
Humberstone AJ, Porter CJH and Charman WN. A physiochemical basis for the effect of food on the absolute bioavailability of halofantrine. J Pharm Sci 1996; 85: 525-529.
-
(1996)
J Pharm Sci
, vol.85
, pp. 525-529
-
-
Humberstone, A.J.1
Porter, C.J.H.2
Charman, W.N.3
-
10
-
-
0029082164
-
Cardiac complications of halofantrine: A prospective study of 20 patients
-
Molun E, Le Metayer P and Szwandt S. Cardiac complications of halofantrine: a prospective study of 20 patients. Trans R Soc Trop Med 1995; 89: 430-433.
-
(1995)
Trans R Soc Trop Med
, vol.89
, pp. 430-433
-
-
Molun, E.1
Le Metayer, P.2
Szwandt, S.3
-
11
-
-
0030551456
-
Electrocardiographic changes in antimalarial treatment with halofantrine, pharmacokinetic study, therapeutic deductions
-
Giudicelli CP, Touze JE and Bernard J. Electrocardiographic changes in antimalarial treatment with halofantrine, pharmacokinetic study, therapeutic deductions. J Bull Acad Nat Med 1996; 180: 71-82.
-
(1996)
J Bull Acad Nat Med
, vol.180
, pp. 71-82
-
-
Giudicelli, C.P.1
Touze, J.E.2
Bernard, J.3
-
12
-
-
0030978656
-
X-Ray crystal structure of the antimalarial agent (-)-halofantrine hydrochloride supports stereospecificity for cardiotoxicity
-
Karle JM. X-Ray crystal structure of the antimalarial agent (-)-halofantrine hydrochloride supports stereospecificity for cardiotoxicity. Antimicrob Agents Chemother 1997; 41: 791-794.
-
(1997)
Antimicrob Agents Chemother
, vol.41
, pp. 791-794
-
-
Karle, J.M.1
-
13
-
-
0029926358
-
Lymphatic transport of halofantrine in the triple-cannulated anesthetized rat model: Effect of lipid vehicle dispersion
-
Porter CJH, Charman SA and Charman WN. Lymphatic transport of halofantrine in the triple-cannulated anesthetized rat model: Effect of lipid vehicle dispersion. J Pharm Sci 1996; 85: 351-356.
-
(1996)
J Pharm Sci
, vol.85
, pp. 351-356
-
-
Porter, C.J.H.1
Charman, S.A.2
Charman, W.N.3
-
14
-
-
0029926358
-
Lymphatic transport of halofantrine in the conscious rat when administered as either the free base or the hydrochloride salt: Effect of lipid class and lipid vehicle dispersion
-
Porter CJH, Charman SA, Humberstone AJ and Charman WN. Lymphatic transport of halofantrine in the conscious rat when administered as either the free base or the hydrochloride salt: effect of lipid class and lipid vehicle dispersion. J Pharm Sci 1996; 85: 351-356.
-
(1996)
J Pharm Sci
, vol.85
, pp. 351-356
-
-
Porter, C.J.H.1
Charman, S.A.2
Humberstone, A.J.3
Charman, W.N.4
-
15
-
-
0001212773
-
Stereospecific high performance liquid chromatographic (HPLC) analysis of halofantrine enantiomers in rat plasma
-
Toni JW and Brocks DR. Stereospecific high performance liquid chromatographic (HPLC) analysis of halofantrine enantiomers in rat plasma. Pharm Res 1997; 14 (Suppl.): 568.
-
(1997)
Pharm Res
, vol.14
, Issue.SUPPL.
, pp. 568
-
-
Toni, J.W.1
Brocks, D.R.2
-
16
-
-
0027137381
-
Pharmacokinetics, efficacy and toxicity of parenteral halofantrine in uncomplicated malaria
-
Krishna S, ter Kuile F, Supanaranond W, Pukrittayakamee S, Teja-Isavadharm P, Kyle D and White NJ. Pharmacokinetics, efficacy and toxicity of parenteral halofantrine in uncomplicated malaria. Br J Clin Pharmacol 1993; 36: 585-591.
-
(1993)
Br J Clin Pharmacol
, vol.36
, pp. 585-591
-
-
Krishna, S.1
Ter Kuile, F.2
Supanaranond, W.3
Pukrittayakamee, S.4
Teja-Isavadharm, P.5
Kyle, D.6
White, N.J.7
-
18
-
-
0027275566
-
Physiological parameters in laboratory animals and humans
-
Davies B and Morris T. Physiological parameters in laboratory animals and humans. Pharm Res 1993; 10: 1093-1095.
-
(1993)
Pharm Res
, vol.10
, pp. 1093-1095
-
-
Davies, B.1
Morris, T.2
-
19
-
-
0027233056
-
Direct determination of the enantiomers of halofantrine and its pharmacologically active metabolite N-desbutylhalofantrine by high performance liquid chromatography
-
Terefe H and Blaschke G. Direct determination of the enantiomers of halofantrine and its pharmacologically active metabolite N-desbutylhalofantrine by high performance liquid chromatography. J Chromatogr 1993; 615: 347-351.
-
(1993)
J Chromatogr
, vol.615
, pp. 347-351
-
-
Terefe, H.1
Blaschke, G.2
-
20
-
-
0031852495
-
Association of halofantrine with postprandially derived plasma lipoproteins decreases its clearance relative to administration in the fasted state
-
Humberstone AJ, Porter CJH, Edwards GA and Charman WN. Association of halofantrine with postprandially derived plasma lipoproteins decreases its clearance relative to administration in the fasted state. J Pharm Sci 1998; 87: 936-942.
-
(1998)
J Pharm Sci
, vol.87
, pp. 936-942
-
-
Humberstone, A.J.1
Porter, C.J.H.2
Edwards, G.A.3
Charman, W.N.4
|