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Volumn 27, Issue 5-6, 2006, Pages 1248-1254

Capillary electrophoretic chiral separation of hydroxychloroquine and its metabolites in the microsomal fraction of liver homogenates

(3) Cardoso, Carmem Dickow a,b Jabor, Valquíria A Polisel a Bonato, Pierina Sueli a

a UNIVERSITY OF SÃO PAULO (Brazil)

b CATHOLIC UNIVERSITY OF PELOTAS (Brazil)

Author keywords

Chiral separation; Hydroxychloroquine; In vitro metabolism; Metabolites

Indexed keywords

BIOMOLECULES; CHIRALITY; EXTRACTION; FUSED SILICA; METABOLISM; ORGANIC SOLVENTS;

CAPILLARY ELECTROPHORETIC METHODS; CHIRAL METABOLITES; CHIRAL SEPARATIONS; HYDROXYCHLOROQUINE; IN VITRO METABOLISM; IN-VITRO; LIQUID-LIQUID EXTRACTION; LOW-COSTS; SIMULTANEOUS ANALYSIS; Β-CD;

METABOLITES;

BETA CYCLODEXTRIN DERIVATIVE; BUFFER; DEETHYLCHLOROQUINE; DRUG METABOLITE; HYDROXYCHLOROQUINE; PHOSPHATE; SOLVENT; TOLUENE;

ARTICLE; CAPILLARY ELECTROPHORESIS; CHIRALITY; CONCENTRATION RESPONSE; DRUG STRUCTURE; HUMAN; HUMAN TISSUE; LIQUID LIQUID EXTRACTION; LIVER HOMOGENATE; MICROSOME; PH; SEPARATION TECHNIQUE; VALIDATION PROCESS;

EID: 33645468790 PISSN: 01730835 EISSN: 15222683 Source Type: Journal
DOI: 10.1002/elps.200500752 Document Type: Article

Times cited : (23)

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