Strong versus weak chiral cation exchangers: Comparative evaluation for enantiomer separation of chiral bases by non-aqueous CEC

Journal of Separation Science

Volumn 25, Issue 15-17, 2002, Pages 1269-1283

  Zarbl, Elfriede ^a   Lämmerhofer, Michael ^a   Woschek, Anna ^b   Hammerschmidt, Friedrich ^b   Parenti, Carlo ^c   Cannazza, Guiseppe ^c   Lindner, Wolfgang ^a  

^a Institute of Analytical Chemistry   (Austria)

^b UNIVERSITY OF VIENNA   (Austria)

^c UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

Author keywords

Amino carboxylic acid; Amino phosphoric acid; Amino sulfonic acid; Basic chiral drugs; Non aqueous capillary electrochromatography; Weak strong cation exchange type selectors

Indexed keywords

ALCOHOLS; AMINES; CAPILLARY TUBES; CARBOXYLIC ACIDS; CHROMATOGRAPHIC ANALYSIS; CHROMATOGRAPHY; ELECTROPHORESIS; PH; POSITIVE IONS; SILICA; VELOCITY;

BACKGROUND ELECTROLYTE;

ION EXCHANGE;

2 AMINO 3,3 DIMETHYLBUTANEPHOSPHONIC ACID DERIVATIVE; ALPRENOLOL; ATENOLOL; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; BUNITROLOL; CARBOXYLIC ACID DERIVATIVE; CELIPROLOL; CLENBUTEROL; ELECTROLYTE; EPHEDRINE; MEFLOQUINE; N (4 ALLYLOXY 3,5 DICHLOROBENZOYL) 2 AMINO 3,3 DIMETHYLBUTANEPHOSPHONIC ACID; N (4 ALLYLOXY 3,5 DICHLOROBENZOYL) 2 AMINO 3,3 DIMETHYLBUTANEPHOSPHONIC ACID DERIVATIVE; N (4 ALLYLOXY 3,5 DICHLOROBENZOYL) 2 AMINO 3,3 DIMETHYLBUTANESULFONIC ACID; N (4 ALLYLOXY 3,5 DICHLOROBENZOYL) 3 AMINO 4,4 DIMETHYLPENTANOIC ACID; NIFENALOL; ORCIPRENALINE; PENBUTOLOL; PHOSPHONIC ACID DERIVATIVE; PRONETALOL; RIMITEROL; SALBUTAMOL; SILICON DIOXIDE; SOTALOL; SULFONIC ACID DERIVATIVE; TALINOLOL; TERBUTALINE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ACID BASE BALANCE; ACIDITY; ARTICLE; CAPILLARY CHROMATOGRAPHY; CATION EXCHANGE; CHIRALITY; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG STRUCTURE; DRUG SYNTHESIS; ENANTIOMER; ENANTIOSELECTIVITY; ION EXCHANGE; PH; PRIORITY JOURNAL; SEPARATION TECHNIQUE; VELOCITY;

EID: 0036924631     PISSN: 16159306     EISSN: None     Source Type: Journal    
DOI: 10.1002/1615-9314(20021101)25:15/17<1269::AID-JSSC1269>3.0.CO;2-R     Document Type: Article

References (50)

1. M. Lämmerhofer, F. Svec, J.M.J. Fréchet, W. Lindner, Trends Anal. Chem. 2000, 19, 676-697.
2. G. Gübitz, M.G. Schmid, Enantiomer 2000, 5, 5-11.
3. D. Wistuba, V. Schurig, Electrophoresis 2000, 21, 4136-4158.
4. B. Chankvetadze, G. Blaschke, J. Chromatogr. A 2001, 906, 309-363.
5. S. Fanali, P. Catarcini, G. Blaschke, B. Chankvetadze, Electrophoresis 2001, 22, 3131-3151.
6. C. Fujimoto, Anal. Sci. 2002, 18, 19-25.
7. G.K.E. Scriba, J. Pharm. Biomed. Anal. 2002, 27, 373-399.
8. S. Mayer, V. Schurig, J. High Resol. Chromatogr. 1992, 15, 129-131.
9. J.J. Pesek, M.T. Matyska, J. Chromatogr. A 2000, 887, 31-41.
10. Z. Liu, K. Otsuka, S. Terabe, J. Sep. Sci. 2001, 24, 17-26.
11. Z. Liu, H. Zou, M. Ye, J. Ni, Y. Zhang, Electrophoresis, 1999, 20, 2891-2897.
12. S. Li, D.K. Lloyd, Anal. Chem. 1993, 65, 3684-3690.
13. D.K. Lloyd, S. Li, P. Ryan, J. Chromatogr. A 1995, 694, 285-296.
14. F. Lelievre, C. Yan, R.N. Zare, P. Gareil, J. Chromatogr. A 1996, 723, 145-56.
15. C. Wolf, P.L. Spence, W.H. Pirkle, E.M. Derrico, D.M. Cavender, G.P. Rozing, J. Chromatogr. A 1997, 782, 175-179.
16. M. Lämmerhofer, W. Lindner, J. Chromatogr. A 1998, 829, 115-125.
17. M. Lämmerhofer, E. Tobler, W. Lindner, J. Chromatogr. A 2000, 887, 431-437.
18. E. Tobler, M. Lämmerhofer, W. Lindner, J. Chromatogr. A 2000, 875, 341-352.
19. E. Tobler, M. Lämmerhofer, G. Mancini, W. Lindner, Chirality 2001, 13, 641-647.
20. E. Tobler, M. Lämmerhofer, F. Wuggenig, F. Hammerschmidt, W. Lindner, Electrophoresis 2002, 23, 462-476.
21. M. Girod, B. Chankvetadze, G. Blaschke, J. Chromatogr. A 2000, 887, 439-455.
22. S. Mayer, X. Briand, E. Francotte, J. Chromatogr. A 2000, 875, 331-339.
23. B. Chankvetadze, I. Kartozia, J. Breitkreutz, Y. Okamoto, G. Blaschke, Electrophoresis 2001, 22, 3327-3334.
24. L. Chankvetadze, I. Kartozia, C. Yamamoto, B. Chankvetadze, G. Blaschke, Y. Okamoto, Electrophoresis 2002, 23, 486-493.
25. K. Kawamura, K. Otsuka, S. Terabe, J. Chromatogr. A 2001, 924, 251-257.
26. C. Karlsson, L. Karlsson, D.W. Armstrong, P. Owens, Anal. Chem. 2000, 72, 4394-4401.
27. E. Carlsson, H. Wikstrom, P.K. Owens, Chromatographia 2001, 53, 419-424.
28. C. Desiderio, Z. Aturki, S. Fanali, Electrophoresis 2001, 22, 535-543.
29. D. Wistuba, V. Schurig, Electrophoresis 1999, 20, 2779-2785.
30. D. Wistuba, K. Cabrera, V. Schurig, Electrophoresis 2001, 22, 2600-2605.
31. J.-M. Lin, T. Nakagama, K. Uchiyama, T. Hobo, J. Pharm. Biomed. Anal. 1997, 1351-1358.
32. L. Schweitz, I. Andersson, S. Nilsson, Anal. Chem. 1997, 69, 1179-1183.
33. E.C. Peters, K. Lewandowski, M. Petro, F. Svec, J.M.J. Fréchet, Anal. Commun. 1998, 35, 83-86.
34. M. Lämmerhofer, F. Svec, J.M.J. Fréchet, Anal. Chem. 2000, 72, 4623-4628.
35. M. Lämmerhofer, E.C. Peters, C. Yu, F. Svec, J.M.J. Fréchet, Anal. Chem. 2000, 72, 4614-4622.
36. M. Lämmerhofer, F. Svec, J.M.J. Fréchet, W. Lindner, J. Microcol. Sep. 2000, 12, 597-602.
37. T. Koide, K. Ueno, J. Chromatogr. A 2000, 893, 177-187.
38. T. Koide, K. Ueno, J. Chromatogr. A 2001, 909, 305-315.
39. A. Vegvari, A. Foldesi, C. Hetenyi, O. Kocnegarova, M.G. Schmid, V. Kudirkaite, S. Hjertén, Electrophoresis 2000, 21, 3116-3125.
40. M.G. Schmid, N. Grobuschek, C. Tuscher, G. Gübitz, A. Vegvari, E. Machtejevas, A. Maruska, S. Hjertén, Electrophoresis 2000, 21, 3141-3144.
41. M.G. Schmid, N. Grobuschek, O. Lecnik, G. Gübitz, A. Vegvari, S. Hjertén, Electrophoresis 2001, 22, 2616-2619.
42. Z. Chen, T. Hobo, Anal. Chem. 2001, 73, 3348-3357.
43. J.W. Kang, D. Wistuba, V. Schurig, Electrophoresis 2002, 23, 1116-1120.
44. D. Braghroli, M. Di Bella, Tetrahedron: Asymmetry 1996, 7, 2145-2150.
45. a) J.M. Varlet, N. Collignon, Ph. Savignac, Tetrahedron 181, 37, 3713-3721;
46. b) F. Mathey, Ph. Savignac, Tetrahedron 1978, 34, 649-654;
47. c) F. Hamerschmidt, F. Wuggenig, Tetrahedron: Asymmetry 1999, 10, 1709-1721.
48. L. Lazar, T. Martinek, G. Bernath, F. Fuelop, Synth. Commun. 1998, 28, 219-224.
49. K. Sarmini, E. Kennendler, J. Biochem. Biophys. Methods 1999, 38, 123.
50. S.P. Porras, M.-L. Riekkola, E. Kenndler, J. Chromatogr. A 2001, 905, 259-268.