Rho kinase and protein kinase C involvement in vascular smooth muscle myofilament calcium sensitization in arteries from diabetic rats

British Journal of Pharmacology

Volumn 159, Issue 8, 2010, Pages 1724-1731

  Kizub, Iv ^a   Pavlova, Oo ^a   Johnson, Cd ^b   Soloviev, Ai ^a   Zholos, Av ^b  

^a STATE INSTITUTION NATIONAL RESEARCH CENTER FOR RADIATION MEDICINE OF THE NATIONAL ACADEMY OF MEDICAL SCIENCES OF UKRAINE   (Ukraine)

^b QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

Author keywords

Arterial smooth muscles; Calcium sensitivity; Diabetes; Myofilaments; Phenylephrine; Protein kinase C; Rho kinase; Vascular complications

Indexed keywords

CALCIUM ION; CHELERYTHRINE; FASUDIL; PHENYLEPHRINE; PROTEIN KINASE C; RHO KINASE; STREPTOZOCIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA; ARTICLE; CALCIUM SENSITIZATION; CONTROLLED STUDY; DIABETES MELLITUS; ENZYME ACTIVITY; EXPERIMENTAL RAT; HYPERGLYCEMIA; MALE; MESENTERIC ARTERY; MYOFILAMENT; NONHUMAN; PRIORITY JOURNAL; RAT; SENSITIZATION; SMOOTH MUSCLE CONTRACTION; UPREGULATION; VASCULAR SMOOTH MUSCLE;

1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE; ANIMALS; ARTERIES; BENZOPHENANTHRIDINES; CALCIUM; DIABETES MELLITUS, EXPERIMENTAL; MALE; MUSCLE CONTRACTION; MUSCLE, SMOOTH, VASCULAR; PHENYLEPHRINE; PROTEIN KINASE C; RATS; RATS, SPRAGUE-DAWLEY; RHO-ASSOCIATED KINASES; STREPTOZOCIN;

EID: 77950221837     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2010.00666.x     Document Type: Article

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