Ionizing radiation alters myofilament calcium sensitivity in vascular smooth muscle: Potential role of protein kinase C

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 289, Issue 3 58-3, 2005, Pages

  Soloviev, Anatoly I ^a   Tishkin, Sergey M ^a   Zelensky, Sergey N ^a   Ivanova, Irina V ^a   Kizub, Igor V ^a   Pavlova, Alexandra A ^a   Moreland, Robert S ^b  

^a STATE INSTITUTION NATIONAL RESEARCH CENTER FOR RADIATION MEDICINE OF THE NATIONAL ACADEMY OF MEDICAL SCIENCES OF UKRAINE   (Ukraine)

^b DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

Chelerythrine; Fura 2; Ionized irradiation; Phorbol dibutyrate; Staurosporine

Indexed keywords

CALCIUM ION; CHELERYTHRINE; FURA 2 ACETOXYMETHYL ESTER; PHENYLEPHRINE; PHORBOL DIBUTYRATE; POTASSIUM CHLORIDE; PROTEIN KINASE C; PROTEIN KINASE C INHIBITOR; STAUROSPORINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ATOMIC BOMB; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVATION; GAMMA IRRADIATION; IONIZING RADIATION; MYOFILAMENT; NONHUMAN; PRIORITY JOURNAL; RADIATION EXPOSURE; SMOOTH MUSCLE CONTRACTILITY; THORACIC AORTA; VASCULAR RING; VASCULAR SMOOTH MUSCLE;

ANIMALS; AORTA, THORACIC; CALCIUM; CAPILLARY PERMEABILITY; INTRACELLULAR MEMBRANES; MICROFILAMENTS; MUSCLE, SMOOTH, VASCULAR; OSMOLAR CONCENTRATION; POTASSIUM CHLORIDE; PROTEIN KINASE C; RATS; RATS, INBRED WKY; VASOCONSTRICTION;

EID: 23944437103     PISSN: 03636119     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpregu.00748.2004     Document Type: Article

References (47)

1. Beckman A, Thakore A, Kalinowski B, Harris J, and Creagor M. Radiation therapy impairs-endothelium-dependent vasodilation in humans. J Am Coll Cardiol 37: 761-765, 2001.
2. 2+) sensitization in smooth muscle. J Biol Chem 279: 28998-289003, 2004.
3. Bourlier V, Diserbo M, Joyeux M, Ribuot C, Multon E, Gourmelon P, and Verdetti J. Early effects of acute gamma-radiation on vascular arterial tone. Br J Pharmacol 123: 1168-1172, 1998.
4. Chitaley K and Webb RC. Nitric oxide induces dilation of rat aorta via inhibition of Rho-kinase signaling. Hypertension 39: 438-450, 2002.
5. Chatterjee M and Tejada M. Phorbol ester-induced contraction in chemically skinned vascular smooth muscle. Am J Physiol Cell Physiol 251: C356-C361, 1986.
6. De Nucci G, Gryglewsky R, Warner TD, and Vane JR. Receptor mediated release of endothelium-derived factor and prostacyclin from bovine aortic endothelial cells is coupled. Proc Natl Acad Sci USA 85: 2334-2338, 1988.
7. Fulginiti J, Singer HA, and Moreland RS. Phorbol ester induced contractions of swine carotid artery arc supported by slowly cycling crossbridges which are not dependent on calcium or myosin light chain phosphorylation. J Vasc Res 30: 315-322, 1993.
8. Gopalkrisna R, Chen Z, and Gundimeda U. Nitric oxide and nitric oxide-generating agents induce a reversible inactivation of protein kinase C activity and phorbol ester binding. J Biol Chem 268: 27180-27185, 1993.
9. 2+ indicators with greatly improved fluorescence properties. J Biol Chem 260: 3440-3450, 1985.
10. 2+-independent contraction in vascular smooth muscle. Am J Physiol Cell Physiol 271: C589-C594, 1996.
11. Horowitz A, Menice CB, Laporte R, and Morgan KG. Mechanisms of smooth muscle contraction. Physiol Rev 76: 967-1003, 1996.
12. 2+- sensitivity in rabbit arterial skinned muscle. Br J Pharmacol 111: 311-317, 1994.
13. Jaenke RS, Robbins ME, Bywaters T, Whitehouse E, Rezvani M, and Hopewell JW. Capillary endothelium. Target site of renal radiation injury. Lab Invest 68: 396-405, 1993.
14. Kamm KE and Stull JT. The function of myosin and myosin light chain kinase phosphorylation in smooth muscle. Annu Rev Pharmacol Toxicol 25: 593-620, 1985.
15. Khomazjuk I. The problem of essential hypertension in survivors after Chernobyl catastrophe. In: Proceedings of the 2nd Conference on Long-Term Health Consequences of the Chernobyl Disaster. Geneva, Switzerland: World Health Organization. p. 398-399, 1998.
16. Kitazawa T, Masuo M, and Somlyo AP. G-protein-mediated inhibition of myosin light-chain phosphatase in vascular smooth muscle. Proc Natl Acad Sci USA 88: 9307-9310, 1991.
17. Krasilenko EP. Age dynamics of cerebral blood flow in liquidators of the accident at the Chernnobyl Atomic Energy Station. Lik Sprava 3-4: 27-32, 2002.
18. Kupittayanant S, Burdyga T, and Wary S. The effects of inhibiting Rho-associated kinase with Y-27632 on force and intracellular calcium in human myometrium. Pflügers Arch 443: 112-114, 2001.
19. Lee YH, Kim I, Laporte R, Walsh MP, and Morgan KG. Isozyme-specific inhibitors of protein kinase C translocation: effects on contractility of single permeabilized vascular muscle cells of the ferret. J Physiol 517: 709-720, 1999.
20. Levesque L, Lam MH, Allaire P, Mondat M, Houle S, Beaudoin G, Donath D, and Leclerc G. Effects of radiation exposure on vascular responsiveness. J Cardiovasc Pharmacol 37: 381-393, 2001.
21. Li J, De Leon H, Ebato B, Cui J, Todd J, Chronos NA, and Robinson KA. Endovascular irradiation impairs vascular functional responses in noninjured pig coronary arteries. Cardiovasc Radiat Med 3: 152-162, 2002.
22. Liubchenko PN, Gorenkov RV, Agal'tsov MV, and Shirokova EB. Ultrasound characteristics of common carotid arteries in Chernobyl clean-up crew members long after the accident. Ter Arkh 74: 59-62, 2002.
23. Moreland RS, Pott JWR, Cilea J, and Moreland S. Regulation of a smooth muscle contraction: A hypothesis based on skinned fiber studies. Adv Exp Med Biol 304 61-76, 1991.
24. Nakajima T and Yukawa O. Radiation-induced translocation of protein kinase C through membrane lipid peroxidation in primary cultured rat hepatocytes. Int J Radiat Biol 70: 473-480, 1996.
25. 2+ sensitivity in permeabilized rabbit mesenteric artery. Circ Res 71: 951-959, 1992.
26. Preston DL, Shimizu Y, Pierce DA, Suyama A, and Mabuchi K. Studies of mortality of atomic bomb survivors. Report 13: Solid cancer and noncancer disease mortality: 1950-1997. Radiat Res 160: 381-407, 2003.
27. Qi F, Sugihara T, Hattoru Y, Yamamoto Y, Kanno M, and Abe K. Functional and morphological damage of endothelium in rabbit ear artery following irradiation with cobalt60. Br J Pharmacol 123: 653-660, 1998.
28. Seko T, Ito M, Kureishi Y, Okamoto R, Moriki N, Onishi K, Isaka N, Hartshorne DJ, and Nakano T. Activation of RhoA and inhibition of myosin phosphatase as important components in hypertension in vascular smooth muscle. Circ Res 92: 411-418, 2003.
29. Sheherbatyi AA, Korkushko OO, and Chupryna HM. New approaches to the treatment of the initial manifestations of cerebral circulatory insufficiency. Lik Sprava 1: 70-73, 2000.
30. Shimuzu Y, Pierce DA, Preston DL, and Mabuchi K. Studies of mortality of atomic bomb survivors. Report 12. Part II Noncancer Mortality: 1950-1990. Radiat Res 152: 374-389, 1999.
31. Singer HA, Schworer CM, Sweeley C, and Benscoter H. Activation of protein kinase C isozymes by contractile stimuli in arterial smooth muscle. Arch Biochem Biophys 299: 320-329, 1992.
32. Soloviev A and Bershtein S. The contractile apparatus in vascular smooth muscle cells of spontaneously hypertensive rats possess increased calcium sensitivity: the possible role of protein kinase C. J Hypertens 10: 131-136, 1992.
33. Soloviev A, Parshikov A, and Stefanov A. Evidence for the involvement of protein kinase C in development of endothelium-dependent vascular responses in spontaneously hypertensive rats. J Vasc Res 35: 325-331, 1998.
34. Soloviev A, Stefanov A, Tishkin S, Khromov A, Parshikov Ivanova I A, and Gurney A. Saline containing phosphatidylcholine liposomes possess the ability to restore endothelial function damaged resulting from gamma-irradiation. J Physiol Pharmacol 53: 707-712, 2002.
35. Soloviev A, Tishkin S, Parshikov A, Ivanova I, Goncharov E, and Gurney A. Mechanisms of endothelium dysfunction after ionized radiation: selective impairment of the nitric oxide component of endothelium-dependent vasodilation. Br J Pharmacol 138: 837-842, 2003.
36. Soloviev A, Lehenky V, Zelensky S, and Hellstrand P. Nitric oxide relaxes rat tail artery smooth muscle by cyclic GMP-independent decrease in calcium sensitivity of myofilaments. Cell Calcium 36: 165-173, 2004.
37. 2+ sensitivity of smooth muscle and nonmuscle myosin II: modulated by G proteins, kinases, and myosin phosphatase. Physiol Rev 83: 1325-1258, 2003.
38. Stanton MC, Delaney D, Zderie SA, and Moreland RS. Partial bladder outlet obstruction abolishes the receptor and G-protein dependent increase in calcium sensitivity in rabbit bladder smooth muscle. Am J Physiol Renal Physiol 287: F682-F689, 2004.
39. Steg PG, Gal D, Rongione AJ, DeJesus SR, Clarke RH, Levine HJ, and Isner JM. Effect of argon laser irradiation on rabbit aortic smooth muscle: evidence for endothelium-independent contraction and relaxation. J Cardiovasc Pharmacol 22: 747-753, 1988.
40. Sugihara T, Hattori Y, Yamamoto Y, Qi F, Ichikawa R, Sato A, Liu MY, Abe K, and Kanno M. Preferential impairment of nitric-oxide-mediated endothelium-dependent relaxation in human cervical arteries after irradiation. Circulation 100: 635-641, 1999.
41. Taranenko VM, Tishkin SM, and Rudnev MI. Effect of ionized radiation on the vascular wall reactivity. Dokl Acad Sci USSR 322: 600-603, 1992.
42. Tsymbaliuk VI, Zavture IS, Horbatiuk DL, Dobriak ID, and Lisovyi AS. Comparative clinical pathology of encephalopathy with circulatory dysfunction in those who participated in the clean-up after the Chernobyl accident and in nonirradiated patients. Lik Sprava 3: 11-13, 2001.
43. Varadakr P, Krishna M, and Verma N. Dose-dependent differential expression of protein kinase C isozymes in mouse lymphocytes after gamma irradiation in vivo and ex vivo. Radiat Res 159: 453-457, 2003.
44. Wettschurek N and Offermanns S. Rho/Rho kinase mediated signaling in physiology and pathophysiology. J Mol Med 80: 629-638, 2002.
45. 2+ sensitivity of protein kinase C-induced contraction in rabbit smooth muscle. J Physiol 535: 553-564, 2001.
46. Yamada M, Wong FL, Fujiwara S, Akahoshi M, and Suzuki G. Noncancer disease incidence in atomic bomb survivors, 1958-1998. Radiat Res I 61: 622-632, 2004.
47. Zhong GZ, Chen FR, Bu DF, Wang SH, Pang YZ, and Tang CS. Cobalt-60 gamma radiation increased the nitric oxide generation in cultured rat vascular smooth muscle cells. Life Sci 74: 3055-3063, 2004.