Insight into the mechanism of domain movements and their role in enzyme function: Example of 3-phosphoglycerate kinase

Current Protein and Peptide Science

Volumn 11, Issue 2, 2010, Pages 118-147

  Vas, M ^a   Varga, A ^a   Graczer E ^a  

^a INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

Author keywords

3 phosphoglycerate kinase; Conformational flexibility; Domain motion; Enzyme function; Substrate binding

Indexed keywords

PHOSPHOGLYCERATE KINASE;

BINDING SITE; BIOINFORMATICS; CATALYSIS; CHEMICAL REACTION; CRYSTAL STRUCTURE; DIFFERENTIAL SCANNING CALORIMETRY; ENZYME ACTIVITY; ENZYME BINDING; ENZYME KINETICS; ENZYME STRUCTURE; ENZYME SUBSTRATE; FLUORESCENCE RESONANCE ENERGY TRANSFER; HINGE REGION; HUMAN; HYDROGEN BOND; INFRARED SPECTROSCOPY; LIGAND BINDING; MUTATIONAL ANALYSIS; NUCLEOTIDE BINDING SITE; PHYSICAL CHEMISTRY; PROTEIN ANALYSIS; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN FUNCTION; RADIATION SCATTERING; REVIEW; SITE DIRECTED MUTAGENESIS;

ANIMALS; CATALYSIS; CRYSTALLOGRAPHY, X-RAY; GLYCERIC ACIDS; HUMANS; KINETICS; MODELS, MOLECULAR; PHOSPHOGLYCERATE KINASE; PROTEIN STRUCTURE, TERTIARY;

EID: 77950170511     PISSN: 13892037     EISSN: None     Source Type: Journal    
DOI: 10.2174/138920310790848403     Document Type: Review

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