Stem cell-derived hepatocytes and their use in toxicology

Toxicology

Volumn 270, Issue 1, 2010, Pages 3-9

  Guguen Guillouzo, Christiane ^a   Corlu, Anne ^a   Guillouzo, Andre ^a  

^a UNIVERSITÉ DE RENNES 1   (France)

Author keywords

Adult stem cells; Cytochrome P450; Drug metabolism; Embryonic stem cells; HepaRG cells; Hepatocyte like cells; Induced pluripotent stem cells; Toxicology

Indexed keywords

CYTOCHROME P450; CYTOCHROME P450 2B6; CYTOCHROME P450 3A4; HEPATOCYTE NUCLEAR FACTOR 3ALPHA; HEPATOCYTE NUCLEAR FACTOR 4; KRUPPEL LIKE FACTOR 4; MESSENGER RNA; MYC PROTEIN; NOTCH3 RECEPTOR; OCTAMER TRANSCRIPTION FACTOR 4; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR SOX2;

ADULT STEM CELL; CELL DIFFERENTIATION; EMBRYONIC STEM CELL; FETUS LIVER; GENE EXPRESSION REGULATION; HEMATOPOIETIC STEM CELL; HUMAN; LIVER CELL; LIVER CELL CARCINOMA; LIVER DEVELOPMENT; NONHUMAN; NUCLEAR REPROGRAMMING; PRIORITY JOURNAL; REVIEW; SOMATIC CELL GENETICS; STEM CELL; TOXICITY TESTING; TUMOR CELL; XENOBIOTIC METABOLISM;

ADULT; ANIMALS; CELL LINE, TUMOR; EMBRYONIC STEM CELLS; FEMALE; HEPATOCYTES; HUMANS; HYBRID CELLS; LIVER; LIVER NEOPLASMS; PREGNANCY; STEM CELLS; TOXICOLOGY;

EID: 77950020144     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2009.09.019     Document Type: Review

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