Species differences in the in vitro metabolism of deltamethrin and esfenvalerate: Differential oxidative and hydrolytic metabolism by humans and rats

Drug Metabolism and Disposition

Volumn 34, Issue 10, 2006, Pages 1764-1771

  Godin, Stephen J ^b   Scollon, Edward J ^a   Hughes, Michael F ^a   Potter, Philip M ^c   DeVito, Michael J ^a,e   Ross, Matthew K ^d  

^a U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

^c ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^d MISSISSIPPI STATE UNIVERSITY   (United States)

^e U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOXYLESTERASE; CARBOXYLESTERASE 1; CARBOXYLESTERASE 2; DELTAMETHRIN; FENVALERATE; HYDROLASE; PESTICIDE; PYRETHROID; RECOMBINANT ENZYME; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; UNCLASSIFIED DRUG;

AEROBIC METABOLISM; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOTRANSFORMATION; BODY WEIGHT; CONTROLLED STUDY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; HYDROLYSIS; IN VITRO STUDY; LIVER CLEARANCE; LIVER MICROSOME; MALE; NONHUMAN; OXIDATION; PRIORITY JOURNAL; RAT; SPECIES DIFFERENCE; TOXICOKINETICS;

ANIMALS; CARBOXYLESTERASE; CARBOXYLIC ESTER HYDROLASES; HUMANS; HYDROLYSIS; LIVER; MALE; METABOLIC DETOXICATION, PHASE I; MICROSOMES, LIVER; NITRILES; PYRETHRINS; RATS; RATS, LONG-EVANS; SPECIES SPECIFICITY;

RODENTIA;

EID: 33748901822     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.106.010058     Document Type: Article

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