Comparative study on glutathione transferases of rat brain and testis under the stress of phenobarbitol and β-methylcholanthrene

Journal of Zhejiang University: Science

Volumn 6 B, Issue 8, 2005, Pages 759-769

  Thyagaraju, K ^a   Hemavathi, B ^a   Vasundhara, K ^a   Rao, A D ^a   Devi, K N ^a  

^a SRI VENKATESWARA UNIVERSITY   (India)

Author keywords

Methylcholanthrene; Brain; Glutathione transferases; Phenobarbitol; Testis

Indexed keywords

AFFINITY CHROMATOGRAPHY; BRAIN; ISOMERIZATION; PH; PROTEINS; PURIFICATION; REDUCTION; TOXICITY;

CHEMICAL TOXICITY; GLUTATHIONE TRANSFERASES (GST); IMMUNOBLOT ANALYSIS; METHYLCHOLANTHRENE (MC); MULTIFUNCTIONAL PROTEINS; MULTIPLE ISOZYMES; PHENOBARBITOL (PB); POLYBUFFER EXCHANGER CHROMATOGRAM; TESTIS;

ENZYMES;

3 METHYLCHOLANTHRENE; GLUTATHIONE TRANSFERASE; PHENOBARBITAL;

ANIMAL; ARTICLE; BRAIN; DRUG EFFECT; ENZYMOLOGY; EXERCISE TEST; GENE EXPRESSION REGULATION; MALE; METABOLISM; PHYSIOLOGY; RAT; TESTIS; WISTAR RAT;

ANIMALS; BRAIN; EXERCISE TEST; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLUTATHIONE TRANSFERASE; MALE; METHYLCHOLANTHRENE; PHENOBARBITAL; RATS; RATS, WISTAR; TESTIS;

EID: 24044443913     PISSN: 10093095     EISSN: None     Source Type: Journal    
DOI: 10.1631/jzus.2005.B0759     Document Type: Article

References (51)

1. Abramovitz, M., Homma, H., Ishigaki, S., Tancey, F., Cammer, W., Listowsky, I., 1988. Characterization and localization of glutathione S-transferase in rat brain. J. Neurochem., 50: 50-57.
2. Aliya, S., Reddanna, P., Thyagaraju, K., 2003. Does glutathione S-transferase pi a carcinogenic marker? Molecular and Cellular Biochemistry, 253: 313-318.
3. Awasthi, Y., Singh, S.V., 1985. Subunit structure of human and rat glutathione S-transferases. Comp. Biochem. Physiol., 82B: 17-23.
4. Beckett, G.J., Hayes, J.D., 1993. Glutathione S transferases: Biomedical applications. Adv. Clin. Chem., 30: 281-380.
5. Beckett, G.J., Hussey, A.J., Laing, I., Howie, A.F., Hayes, J.D., Strange, R.C., Faulder, C.G., Hume, R., 1989. Measurements of glutathione S transferases B1 in plasma after birth asphyxia: An early indication of hepatocellular damage. Clin. Chem., 35: 995-999.
6. Board, P.G., Coggan, M., Chelvanayagam, G., Easteal, S., Jermiin, L.S., Schulte, G.K., Danley, D.B., Hoth, L.R., Griffor, M.C., Kamath, A.V., Rosner, M.H, Chrunyk, B.A., Perregaux, D.B., Gabel, C.A., Geoghegan, K.F., Pandit, J., 2000. Identification, characterization and crystal structure of the omega class glutathione transferases. J. Biol. Chem., 275: 24798-24806.
7. 2. Arch. Biochem. Biophy., 259: 548-557.
8. Clifton, G., Kaplowitz, N., 1978. Effect of dietary phenobarbitol, 3,4-benzopyrene and 3-methlycholanthrene on hepatic, intestinal and renal glutathione S-transferase activity in the rat. Biochem. Pharmacol., 27: 1284-1287.
9. Coles, B., Ketterer, B., 1990. The role of glutathione and glutathione transferases in chemical carcinogenesis. Crit. Rev. Biochem. Mol. Biol., 25: 47-70.
10. Devi, K.N., Reddy, C.C., Raveendra, A., Thyagaraju, K., 2002a. Effect of β-methyl cholanthrene on glutathione S-transferases of rat testis. Current Sci., 82: 1282-1287.
11. Devi, K.N., Hemavathi, B., Aliya, S., Raveendra, A., Thyagaraju, K., 2002b. A comparative study on the effect of PB and MC on glutathione S transferases of rat testis. J. Biochem. Molbiol. Biophys., 6(6): 373-378.
12. Dragan, Y.P., Singh, J., Pitit, H.C., 1996. Effect of separate and combined administration of mestranol and PB on glutathione S transferases of rat testis. Journal of Biochemistry, Molecular Biology and Biophysics, 6: 373-378.
13. Feinfeld, D.A., Fleischner, G.M., Arias, I.M., 1981. Urinary ligandin and glutathioen S tarnsferases in Gentamicin induced nephrotoxicity in the rat. Clin. Sci., 61: 123-125.
14. Guthenberg, C., Morgenstern, R., Depierre, J.W., Mannervik, B., 1980. Induction of GSTs A, B and C in rat liver cytosol by trans stillbene oxide. Biochem. Biophys. Acta, 631: 1-10.
15. Guthenberg, C., Astrand, I.M., Alin, P., Mannervik, B., 1983. Glutathione S-transferase in rat testis. Acta. Chem. Scand. Ser., B37: 261.
16. Habig, W.H., Jakoby, W.B., 1981. Assays for differentiation of glutathione S-transferases. Methods Enzymol., 77: 398-405.
17. Habig, W.H., Pabst, M.J., Jakoby, W.B., 1974. Glutathione S-transferase the firstenzymatic step in mercapturic acid formation. J. Biol. Chem., 249: 7130-7139.
18. Hayes, J.D., Mantle, T.J., 1986. Inhibition of hepatic and extrahepatic glutathione S-transferases by primary and secondary bile acids. Biochem. J., 233: 779-788.
19. Hayes, P.C., Portman, B., Aldis, P.M., Williams, R., Hayes, J.D., 1987. Glutathione S-Transferases and Human Pathology. In: Mantle, T.J., Pickett, C.B., Hayes, J.D. (Eds.), Glutathione S-transferases and Carcinogenesis. Taylor and Francis, London, p. 175-187.
20. Hayes, P.C., Hussey, A.J., Keating, J., Bouchier, I.A.D., Williams, R., Beckett, G.J., Hayes, J.D., 1988. Glutathione S transferase level in autoimmune chronic active hepatitis: A more sensitive index of hepatocellular damage than aspartate transaminase. Clin. Chem. Acta, 172: 211-216.
21. Hiratsuka, A., Sebata, N., Kswashima, K., Okuda, H., Ogura, K., Watabe, T., Satoh, K., Hatayama, I., Tsuchida, S., Ishikawa, T., Sat, K., 1990. A new class of rat glutathione S transferase Yrs-Yrs inactivating reactive sulphate esters as metabolites of carcinogenic aryl methanols. J. Biol. Chem., 265: 11973-11981.
22. Howie, A.W., Patrick, B.M., Fisher, A., Collier Frier, B.M., Beckett, G.J., 1989. Plasma hepatic glutathione S tarnsferase concentrations after insulin induced hypoglycemia in normal subjects and diabetic patients. Diabetic Med., 6: 224-227.
23. Kaplowitz, N., Kuhlen Kamp, J., Clifton, G., 1975. Drug induction of hepatic glutathione S-transferase in male and female rats. Biochem. J., 146: 351-356.
24. Ketterer, B., Tan, K.H., Meyer, D.J., Coles, B., 1987. Glutathione S-Transferases and Carcinogenesis. In: Mantle, T.J., Pickett, C.B., Hayes, J.D. (Eds.), Taylor and Francis. London, p. 149-164.
25. Kitahara, A., Satoh, K., Nishimura, K., Ishikawa, T., Ruike, K., Sato, K., Tsuda, H., Ito, N., 1984. Changes in molecular forms of rat hepatic glutathione S transferase durin chemical hepato carcinogenesis. Cancer Res., 44: 2698-2703.
26. Klys, H.S., Whillis, D., Howard, G., Harrison, D.J., 1992. Glutathione S-transferase expression in human testis and testicular germ cell neoplasia. Br. J. Cancer, 66: 589-593.
27. Laemmli, U.K., 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature, 227: 680-685.
28. Li, N., Reddanna, P., Thyagaraju, K., Reddy, C.C., Tu, C.P.D., 1986. Expression of glutathione S-transferases in rat brain. J. Biol. Chem., 261: 7596-7599.
29. Lowry, O.H., Rosebrough, N.J., Farr, A.L., Randall, R.J., 1951. Protein measurement with Folin phenol reagent. J. Biol. Chem., 193: 265-275.
30. Mannervik, B., Danielson, U.K., 1988. Glutathione S-transferases, structure and catalytic activity. CRC. Crit. Rev. Biochem. Mol. Biol., 23: 283-337.
31. Mannervik, B., Awasthi, Y.C., Board, P.G., Hayes, J.D., Dillio, C., Ketterer, B., 1992. Nomenclature of human glutathione transferases. Biochem. J., 282: 305-306.
32. Meyer, D.J., Beale, D., Tan, K.H., Cole, B., Ketterer, B., 1985. Glutathione S-transferases in primary rat hepatomas: The isolation of a form with glutathione peroxidase activity. FEBS Lett., 184: 139-143.
33. Meyer, D.J., Coles, B., Pemble, S.E., Gilmore, K.S., Fraser, G.M., Ketterer, B., 1991. Theta, a new class of glutathione S-transferases purified from rat and man. Biochem. J., 274: 409-414.
34. Morton, M.R., Bayney, R.M., Pickett, C.B., 1990. Isolation and characterization of the rat GSTs-Yb subunit gene. Archives of Biochemistry and Biophysics, 277: 56-60.
35. Ouchterlony, O., 1966. Handbook of Immunodiffusion and Immuno Electrophoresis. 2nd Ed., An Arbore Publishers, Ann Arbor.
36. Rabahi, F., Brule, S., Sirois, J., Beckers, J.F., Silversides, D.W., Lussier, J.G., 1999. High expression of bovine alpha glutathione S-transferase (GSTA1 and GSTA2) subunits is mainly associated with steroidogenically active cells and regulated by gonadotrophins in bovine ovarian follicles. Endocrinology, 140: 3507-3517.
37. Reynaud, S., Marionnet, D., Taysse, L., Duchiron, C., Deschaux, P., 2002. The effects of 3-methylcholanthrene on macrophage respiratory burst and bio-transformation activities in the common carp (Cyprinus carpio L.). Fish Shellfish Immunol, 12: 17-34.
38. Rowet, J.D., Patskovisky, Y.V., Patskovska, L.N., Novikova, E., Listowisky, I., 1998. Rationale for reclassification of a distinctive subdivision of mammalian class mu glutathione S-transferases that are primarily expressed in testis. J. Biol. Chem., 273: 9593-9601.
39. Rushmore, T.H., Sharma, R.N.S., Roomi, M.W., Harris, L., Satoh, K., Sato, K., Murray, R.K., Farber, E., 1987. Identification of a characteristic cytosolic poly peptide of rat preneoplastic hepatocyte nodules as placental glutathione S transferase. Biochem. Biophys. Res. Commun, 143: 98-103.
40. Sato, K., Kitahara, A., Satoh, Y., Ishikawa, T., Tatematsu, M., Ito, N., 1984. The placental form of glutathione S transferase as a new marker protein for preneoplasia in rat chemical carcinogenesis, Gann. Jpn. J. Cancer Res., 75: 199-202.
41. Satoh, K., Kitahara, A., Soma, Y., Inaba, Y., Hatayama, I., Sato, K., 1985. Purification, induction and distribution of placental glutathione S-transferases: A new marker enzyme for preneoplastic cells in the rat chemical hepato carcinogenesis. Proc. Natl. Acad. Sci. USA, 82: 3964-3968.
42. Singh, S.V., Saunders, M.O., Moller, P.C., Haber, B., Aswasthi, Y.C., 1987. Comparative studies on the isoenzymes of glutathione S-transferase of rat brain and other tissues. Comp. Biochem. Physiol., 86B: 73-81.
43. Tahir, M.K., Mannervik, B., 1986. Simple inhibition studies for distinction between homodimeric and heterodimeric isoenzymes of glutathione S transferases. J. Biol. Chem., 261: 1048-1051.
44. Thyagaraju, K., Reddanna, P., Nirmala Devi, K., Hildenbrandt, G.R., Reddy, C.C., 1994. Structural multiplicity of glutathione S-transferases. J. Parasit. Appl. Anim. Biol., 3(1): 23-29.
45. Thyagaraju, K., Devi, K.N., Hildenbrandt, G.R., Reddy, C.C., 1996. Purification and characterization of 12 forms of rat brain GSTs. J. Parasitol. Appl. Animal. Biol., 5(1): 33-48.
46. Thyagaraju, K., Vasundhara, K., Hemavathi, B., Uma, A., Devi, K.N., 2004. Effect of phenobarbitol on the induction of glutathione S-transferases in rat testis. Reproductive Biomedicine Online, 8(1): 68-74.
47. Towbin, H.T., Staehelin, J., Gordon, J., 1979. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications. Proc. Natl. Acad. Sci. USA, 7614: 4350-4354.
48. Trull, A.K., Facey, S.P., Rees, G.W., Wight, D.P.D., Nobile-Jamieson, G., Joughin, C., Friend, P.J., Alexander, G.J.M., 1994. Serum alpha-glutathione S transferase: A sensitive marker of hepatocellular damage associated with acute liver allograft rejection. Transplantation, 58: 1345-1351.
49. Tu, C.P.D., Reddy, C.C., 1985. On the multiplicity of rat liver glutathione S-transferases. J. Biol. Chem., 260: 9961-9964.
50. Warburg, O., Christian, W., 1941. Isolierung und kristallisation des gärungsferments enolase. Biochemische Zeitschrift, 310: 384-421.
51. Wendel, A., 1981. Enzymatic Basis of Detoxification. In: Jakoby, W.B. (Ed.), Glutathione. Academic Press, New York, 1: 333-353.