-
1
-
-
53049089639
-
Direct and potent regulation of gamma-secretase by its lipid microenvironment
-
Osenkowski P, Ye W, Wang R, Wolfe MS, Selkoe DJ. Direct and potent regulation of gamma-secretase by its lipid microenvironment. J Biol Chem 2008;283:22529-22540.
-
(2008)
J Biol Chem.
, vol.283
, pp. 22529-22540
-
-
Osenkowski, P.1
Ye, W.2
Wang, R.3
Wolfe, M.S.4
Selkoe, D.J.5
-
2
-
-
0035476329
-
Spatial control of cellular measurements with the laser micropipet
-
Li H, Sims CE, Wu HY, Allbritton NL. Spatial control of cellular measurements with the laser micropipet. Anal Chem 2001;73:4625-4631.
-
(2001)
Anal Chem.
, vol.73
, pp. 4625-4631
-
-
Li, H.1
Sims, C.E.2
Wu, H.Y.3
Allbritton, N.L.4
-
3
-
-
55249104596
-
Current techniques for single-cell lysis
-
Brown RB, Audet J. Current techniques for single-cell lysis. J R Soc Interface 2008;5(Suppl 2):S131-S138.
-
(2008)
J R Soc Interface
, vol.5
, Issue.SUPPL 2
-
-
Brown, R.B.1
Audet, J.2
-
4
-
-
0032496358
-
The biochemical basis of an all-or-none cell fate switch in Xenopus oocytes
-
Ferrell JE Jr, Machleder EM. The biochemical basis of an all-or-none cell fate switch in Xenopus oocytes. Science 1998;280:895-898.
-
(1998)
Science
, vol.280
, pp. 895-898
-
-
Ferrell Jr., J.E.1
MacHleder, E.M.2
-
5
-
-
0037310819
-
Single-cell kinase assays: Opening a window onto cell behavior
-
Sims CE, Allbritton NL. Single-cell kinase assays: Opening a window onto cell behavior. Curr Opin Biotechnol 2003;14:23-28.
-
(2003)
Curr Opin Biotechnol
, vol.14
, pp. 23-28
-
-
Sims, C.E.1
Allbritton, N.L.2
-
6
-
-
33947686032
-
Analysis of single mammalian cells on-chip
-
Sims CE, Allbritton NL. Analysis of single mammalian cells on-chip. Lab Chip 2007;7:423-440.
-
(2007)
Lab Chip
, vol.7
, pp. 423-440
-
-
Sims, C.E.1
Allbritton, N.L.2
-
7
-
-
0030590875
-
Molecular basis for the substrate specificity of protein kinase B; Comparison with MAPKAP kinase-1 and p70 S6 kinase
-
Alessi DR, Caudwell FB, Andjelkovic M, Hemmings BA, Cohen P. Molecular basis for the substrate specificity of protein kinase B; comparison with MAPKAP kinase-1 and p70 S6 kinase. FEBS Lett 1996;399:333-338.
-
(1996)
FEBS Lett.
, vol.399
, pp. 333-338
-
-
Alessi, D.R.1
Caudwell, F.B.2
Andjelkovic, M.3
Hemmings, B.A.4
Cohen, P.5
-
8
-
-
0034946412
-
Determination of protease cleavage site motifs using mixture-based oriented peptide libraries
-
Turk BE, Huang LL, Piro ET, Cantley LC. Determination of protease cleavage site motifs using mixture-based oriented peptide libraries. Nat Biotechnol 2001;19:661-667.
-
(2001)
Nat Biotechnol
, vol.19
, pp. 661-667
-
-
Turk, B.E.1
Huang, L.L.2
Piro, E.T.3
Cantley, L.C.4
-
9
-
-
3142651375
-
Characterization of TAT-mediated transport of detachable kinase substrates
-
Soughayer JS, Wang Y, Li H, Cheung SH, Rossi FM, Stanbridge EJ, Sims CE, Allbritton NL. Characterization of TAT-mediated transport of detachable kinase substrates. Biochemistry 2004;43:8528-8540.
-
(2004)
Biochemistry
, vol.43
, pp. 8528-8540
-
-
Soughayer, J.S.1
Wang, Y.2
Li, H.3
Cheung, S.H.4
Rossi, F.M.5
Stanbridge, E.J.6
Sims, C.E.7
Allbritton, N.L.8
-
10
-
-
61649121919
-
Selective enhancement of the uptake and bioactivity of a TAT-conjugated peptide inhibitor of glycogen synthase kinase-3
-
Manceur AP, Driscoll BD, Sun W, Audet J. Selective enhancement of the uptake and bioactivity of a TAT-conjugated peptide inhibitor of glycogen synthase kinase-3. Mol Ther 2009;17:500-507.
-
(2009)
Mol Ther.
, vol.17
, pp. 500-507
-
-
Manceur, A.P.1
Driscoll, B.D.2
Sun, W.3
Audet, J.4
-
11
-
-
33645323807
-
Imaging specific cell-surface proteolytic activity in single living cells
-
Hobson JP, Liu S, Rono B, Leppla SH, Bugge TH. Imaging specific cell-surface proteolytic activity in single living cells. Nat Methods 2006;3:259-261.
-
(2006)
Nat Methods
, vol.3
, pp. 259-261
-
-
Hobson, J.P.1
Liu, S.2
Rono, B.3
Leppla, S.H.4
Bugge, T.H.5
-
12
-
-
1042265207
-
A quantitative single-cell assay for protein kinase B reveals important insights into the biochemical behavior of an intracellular substrate peptide
-
Li H, Sims CE, Kaluzova M, Stanbridge EJ, Allbritton NL. A quantitative single-cell assay for protein kinase B reveals important insights into the biochemical behavior of an intracellular substrate peptide. Biochemistry 2004;43:1599-1608.
-
(2004)
Biochemistry
, vol.43
, pp. 1599-1608
-
-
Li, H.1
Sims, C.E.2
Kaluzova, M.3
Stanbridge, E.J.4
Allbritton, N.L.5
-
14
-
-
0032215305
-
Lasermicropipet combination for single-cell analysis
-
Sims CE, Meredith GD, Krasieva TB, Berns MW, Tromberg BJ, Allbritton NL. Lasermicropipet combination for single-cell analysis. Anal Chem 1998;70:4570-4577.
-
(1998)
Anal Chem.
, vol.70
, pp. 4570-4577
-
-
Sims, C.E.1
Meredith, G.D.2
Krasieva, T.B.3
Berns, M.W.4
Tromberg, B.J.5
Allbritton, N.L.6
-
15
-
-
13244283092
-
Chemical cytometry for monitoring metabolism of a Ras-mimicking substrate in single cells
-
Arkhipov SN, Berezovski M, Jitkova J, Krylov SN. Chemical cytometry for monitoring metabolism of a Ras-mimicking substrate in single cells. Cytometry Part A 2005;63A:41-47.
-
(2005)
Cytometry Part A
, vol.63
, Issue.A
, pp. 41-47
-
-
Arkhipov, S.N.1
Berezovski, M.2
Jitkova, J.3
Krylov, S.N.4
-
16
-
-
0033197985
-
Correlating cell cycle with metabolism in single cells: Combination of image and metabolic cytometry
-
Krylov SN, Zhang Z, Chan NW, Arriaga E, Palcic MM, Dovichi NJ. Correlating cell cycle with metabolism in single cells: Combination of image and metabolic cytometry. Cytometry 1999;37:14-20.
-
(1999)
Cytometry
, vol.37
, pp. 14-20
-
-
Krylov, S.N.1
Zhang, Z.2
Chan, N.W.3
Arriaga, E.4
Palcic, M.M.5
Dovichi, N.J.6
-
17
-
-
33846682918
-
Counting low-copy number proteins in a single cell
-
Huang B, Wu H, Bhaya D, Grossman A, Granier S, Kobilka BK, Zare RN. Counting low-copy number proteins in a single cell. Science 2007;315:81-84.
-
(2007)
Science
, vol.315
, pp. 81-84
-
-
Huang, B.1
Wu, H.2
Bhaya, D.3
Grossman, A.4
Granier, S.5
Kobilka, B.K.6
Zare, R.N.7
-
18
-
-
3042698096
-
Asymmetry between sister cells in a cancer cell line revealed by chemical cytometry
-
Hu K, Ahmadzadeh H, Krylov SN. Asymmetry between sister cells in a cancer cell line revealed by chemical cytometry. Anal Chem 2004;76:3864-3866.
-
(2004)
Anal Chem.
, vol.76
, pp. 3864-3866
-
-
Hu, K.1
Ahmadzadeh, H.2
Krylov, S.N.3
-
19
-
-
4444367423
-
Chemical cytometry on a picoliter-scale integrated microfluidic chip
-
Wu H, Wheeler A, Zare RN. Chemical cytometry on a picoliter-scale integrated microfluidic chip. Proc Natl Acad Sci USA 2004;101:12809-12813.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 12809-12813
-
-
Wu, H.1
Wheeler, A.2
Zare, R.N.3
-
20
-
-
34547420657
-
Single-cell measurements with mass spectrometry
-
Xu X-HN, editor, Hoboken, New Jersey: John Wiley & Sons
-
Monroe EB, Jurchen JC, Rubakhin SS, Sweedler JV. Single-cell measurements with mass spectrometry. In: Xu X-HN, editor. New Frontiers in Ultrasensitive Bioanalysis: Advanced Analytical Chemistry Applications in Nanobiotechnology, Single Molecule Detection, and Single Cell Analysis. Hoboken, New Jersey: John Wiley & Sons; 2007. pp 269-293.
-
(2007)
New Frontiers in Ultrasensitive Bioanalysis: Advanced Analytical Chemistry Applications in Nanobiotechnology, Single Molecule Detection, and Single Cell Analysis
, pp. 269-293
-
-
Monroe, E.B.1
Jurchen, J.C.2
Rubakhin, S.S.3
Sweedler, J.V.4
-
21
-
-
70449857638
-
Situ metabolic profiling of single cells by laser ablation electrospray ionization mass spectrometry
-
Shrestha B, Vertes A. In situ metabolic profiling of single cells by laser ablation electrospray ionization mass spectrometry. Anal Chem 2009;81:8265-8271.
-
(2009)
Anal Chem
, vol.81
, pp. 8265-8271
-
-
Shrestha, B.1
Vertes, A.2
-
22
-
-
0031569338
-
Analysis of fructans from higher plants by matrix-assisted laser desorption/ionization mass spectrometry
-
Stahl B, Linos A, Karas M, Hillenkamp F, Steup M. Analysis of fructans from higher plants by matrix-assisted laser desorption/ionization mass spectrometry. Anal Biochem 1997;246:195-204.
-
(1997)
Anal Biochem
, vol.246
, pp. 195-204
-
-
Stahl, B.1
Linos, A.2
Karas, M.3
Hillenkamp, F.4
Steup, M.5
-
23
-
-
49149126264
-
Mass spectrometric method for analyzing metabolites in yeast with single cell sensitivity
-
Amantonico A, Oh JY, Sobek J, Heinemann M, Zenobi R. Mass spectrometric method for analyzing metabolites in yeast with single cell sensitivity. Angew Chem Int Ed Engl 2008;47:5382-5385.
-
(2008)
Angew Chem Int Ed Engl.
, vol.47
, pp. 5382-5385
-
-
Amantonico, A.1
Oh, J.Y.2
Sobek, J.3
Heinemann, M.4
Zenobi, R.5
-
24
-
-
33750205820
-
Profiling signaling peptides in single mammalian cells using mass spectrometry
-
Rubakhin SS, Churchill JD, Greenough WT, Sweedler JV. Profiling signaling peptides in single mammalian cells using mass spectrometry. Anal Chem 2006;78:7267-7272.
-
(2006)
Anal Chem.
, vol.78
, pp. 7267-7272
-
-
Rubakhin, S.S.1
Churchill, J.D.2
Greenough, W.T.3
Sweedler, J.V.4
-
25
-
-
51949090814
-
Quantitative measurements of cell-cell signaling peptides with single-cell MALDI MS
-
Rubakhin SS, Sweedler JV. Quantitative measurements of cell-cell signaling peptides with single-cell MALDI MS. Anal Chem 2008;80:7128-7136.
-
(2008)
Anal Chem.
, vol.80
, pp. 7128-7136
-
-
Rubakhin, S.S.1
Sweedler, J.V.2
-
26
-
-
0029685835
-
Analysis of single cells with capillary electrophoresis electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry
-
Hofstadler SA, Severs JC, Smith RD, Swanek FD, Ewing AG. Analysis of single cells with capillary electrophoresis electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry. Rapid Commun Mass Spectrom 1996;10:919-922.
-
(1996)
Rapid Commun Mass Spectrom
, vol.10
, pp. 919-922
-
-
Hofstadler, S.A.1
Severs, J.C.2
Smith, R.D.3
Swanek, F.D.4
Ewing, A.G.5
-
28
-
-
35348951663
-
Sampling efficiency of a single-cell capillary electrophoresis system
-
Brown RB, Audet J. Sampling efficiency of a single-cell capillary electrophoresis system. Cytometry Part A 2007;71A:882-888.
-
(2007)
Cytometry Part A
, vol.71
, Issue.A
, pp. 882-888
-
-
Brown, R.B.1
Audet, J.2
-
29
-
-
0028101148
-
Microcolumn sample injection by spontaneous fluid displacement
-
Fishman H, Scheller R, Zare R. Microcolumn sample injection by spontaneous fluid displacement. J Chromatogr A 1994;680:99-107.
-
(1994)
J Chromatogr A
, vol.680
, pp. 99-107
-
-
Fishman, H.1
Scheller, R.2
Zare, R.3
-
31
-
-
0041589436
-
Partial purification and characterization of gamma-secretase from post-mortem human brain
-
Farmery MR, Tjernberg LO, Pursglove SE, Bergman A, Winblad B, Naslund J. Partial purification and characterization of gamma-secretase from post-mortem human brain. J Biol Chem 2003;278:24277-24284.
-
(2003)
J Biol Chem.
, vol.278
, pp. 24277-24284
-
-
Farmery, M.R.1
Tjernberg, L.O.2
Pursglove, S.E.3
Bergman, A.4
Winblad, B.5
Naslund, J.6
-
33
-
-
75649141318
-
The structure of well-folded beta-hairpin peptides promotes resistance to peptidase degradation
-
Cline LL, Waters ML. The structure of well-folded beta-hairpin peptides promotes resistance to peptidase degradation. Biopolymers 2009;92:502-507.
-
(2009)
Biopolymers
, vol.92
, pp. 502-507
-
-
Cline, L.L.1
Waters, M.L.2
-
34
-
-
33947597857
-
GxxxG motifs within the amyloid precursor protein transmembrane sequence are critical for the etiology of Abeta42
-
Munter LM, Voigt P, Harmeier A, Kaden D, Gottschalk KE, Weise C, Pipkorn R, Schaefer M, Langosch D, Multhaup G. GxxxG motifs within the amyloid precursor protein transmembrane sequence are critical for the etiology of Abeta42. EMBO J 2007;26:1702-1712.
-
(2007)
EMBO J.
, vol.26
, pp. 1702-1712
-
-
Munter, L.M.1
Voigt, P.2
Harmeier, A.3
Kaden, D.4
Gottschalk, K.E.5
Weise, C.6
Pipkorn, R.7
Schaefer, M.8
Langosch, D.9
Multhaup, G.10
-
35
-
-
0032728957
-
Mice lacking both presenilin genes exhibit early embryonic patterning defects
-
Donoviel DB, Hadjantonakis AK, Ikeda M, Zheng H, Hyslop PS, Bernstein A. Mice lacking both presenilin genes exhibit early embryonic patterning defects. Genes Dev 1999;13:2801-2810.
-
(1999)
Genes Dev.
, vol.13
, pp. 2801-2810
-
-
Donoviel, D.B.1
Hadjantonakis, A.K.2
Ikeda, M.3
Zheng, H.4
Hyslop, P.S.5
Bernstein, A.6
-
36
-
-
0036727463
-
Presenilins are not required for A beta 42 production in the early secretory pathway
-
Wilson CA, Doms RW, Zheng H, Lee VM. Presenilins are not required for A beta 42 production in the early secretory pathway. Nat Neurosci 2002;5:849-855.
-
(2002)
Nat Neurosci.
, vol.5
, pp. 849-855
-
-
Wilson, C.A.1
Doms, R.W.2
Zheng, H.3
Lee, V.M.4
-
37
-
-
8744237281
-
Pathway for degradation of peptides generated by proteasomes: A key role for thimet oligopeptidase and other metallopeptidases
-
Saric T, Graef CI, Goldberg AL. Pathway for degradation of peptides generated by proteasomes: A key role for thimet oligopeptidase and other metallopeptidases. J Biol Chem 2004;279:46723-46732.
-
(2004)
J Biol Chem.
, vol.279
, pp. 46723-46732
-
-
Saric, T.1
Graef, C.I.2
Goldberg, A.L.3
-
38
-
-
67649804558
-
Analysis of intracellular substrates and products of thimet oligopeptidase in human embryonic kidney 293 cells
-
Berti DA, Morano C, Russo LC, Castro LM, Cunha FM, Zhang X, Sironi J, Klitzke CF, Ferro ES, Fricker LD. Analysis of intracellular substrates and products of thimet oligopeptidase in human embryonic kidney 293 cells. J Biol Chem 2009;284:14105-14116.
-
(2009)
J Biol Chem.
, vol.284
, pp. 14105-14116
-
-
Berti, D.A.1
Morano, C.2
Russo, L.C.3
Castro, L.M.4
Cunha, F.M.5
Zhang, X.6
Sironi, J.7
Klitzke, C.F.8
Ferro, E.S.9
Fricker, L.D.10
-
39
-
-
0038771182
-
RIPped out by presenilin-dependent gamma-secretase
-
Medina M, Dotti CG. RIPped out by presenilin-dependent gamma-secretase. Cell Signal 2003;15:829-841.
-
(2003)
Cell Signal.
, vol.15
, pp. 829-841
-
-
Medina, M.1
Dotti, C.G.2
-
40
-
-
35448991324
-
Extracellular control of TGFbeta signalling in vascular development and disease
-
ten Dijke P, Arthur HM. Extracellular control of TGFbeta signalling in vascular development and disease. Nat Rev Mol Cell Biol 2007;8:857-869.
-
(2007)
Nat Rev Mol Cell Biol.
, vol.8
, pp. 857-869
-
-
Ten Dijke, P.1
Arthur, H.M.2
-
41
-
-
33747623018
-
Notch signalling: A simple pathway becomes complex
-
Bray SJ. Notch signalling: A simple pathway becomes complex. Nat Rev Mol Cell Biol 2006;7:678-689.
-
(2006)
Nat Rev Mol Cell Biol.
, vol.7
, pp. 678-689
-
-
Bray, S.J.1
|