메뉴 건너뛰기




Volumn 159, Issue 7, 2010, Pages 1440-1449

Impaired transactivation of the human CYP2J2 arachidonic acid epoxygenase gene in HepG2 cells subjected to nitrative stress: Research paper

Author keywords

Activator protein 1; Cytochrome P450 2J2; Epoxyfatty acids; Gene regulation; Nitrative stress

Indexed keywords

CYTOCHROME P450 2J2; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; NITROPRUSSIDE SODIUM; PROTEIN C FOS; PROTEIN C JUN; TRANSCRIPTION FACTOR AP 1;

EID: 77949779917     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2009.00628.x     Document Type: Article
Times cited : (19)

References (42)
  • 1
    • 57149086269 scopus 로고    scopus 로고
    • Epoxyeicosatrienoic acid prevents postischemic electrocardiogram abnormalities in an isolated heart model
    • Batchu SN, Law E, Brocks DR, Falck JR, Seubert JM (2009). Epoxyeicosatrienoic acid prevents postischemic electrocardiogram abnormalities in an isolated heart model. J Mol Cell Cardiol 46: 67 74.
    • (2009) J Mol Cell Cardiol , vol.46 , pp. 67-74
    • Batchu, S.N.1    Law, E.2    Brocks, D.R.3    Falck, J.R.4    Seubert, J.M.5
  • 2
    • 0026728159 scopus 로고
    • Incorporation and distribution of epoxyeicosatrienoic acids into cellular phospholipids
    • Bernstrom K, Kayganich K, Murphy RC, Fitzpatrick FA (1992). Incorporation and distribution of epoxyeicosatrienoic acids into cellular phospholipids. J Biol Chem 267: 3638 3690.
    • (1992) J Biol Chem , vol.267 , pp. 3638-3690
    • Bernstrom, K.1    Kayganich, K.2    Murphy, R.C.3    Fitzpatrick, F.A.4
  • 3
    • 4644273095 scopus 로고    scopus 로고
    • Counting on mitogen-activated protein kinases - ERKs 3, 4, 5, 6, 7 and 8
    • Bogoyevitch MA, Court NW (2004). Counting on mitogen-activated protein kinases - ERKs 3, 4, 5, 6, 7 and 8. Cell Signal 16: 1345 1354.
    • (2004) Cell Signal , vol.16 , pp. 1345-1354
    • Bogoyevitch, M.A.1    Court, N.W.2
  • 4
    • 54049141728 scopus 로고    scopus 로고
    • Mitogen-activated protein (MAP) kinase/MAP kinase phosphatase regulation: Roles in cell growth, death, and cancer
    • Boutros T, Chevet E, Matrakos P (2008). Mitogen-activated protein (MAP) kinase/MAP kinase phosphatase regulation: roles in cell growth, death, and cancer. Pharmacol Rev 60: 261 310.
    • (2008) Pharmacol Rev , vol.60 , pp. 261-310
    • Boutros, T.1    Chevet, E.2    Matrakos, P.3
  • 5
    • 0039137646 scopus 로고    scopus 로고
    • Role of mitogen-activated protein kinases in S-nitrosoglutathione-induced macrophage apoptosis
    • Callsen D, Brüne B (1999). Role of mitogen-activated protein kinases in S-nitrosoglutathione-induced macrophage apoptosis. Biochemistry 38: 2279 2286.
    • (1999) Biochemistry , vol.38 , pp. 2279-2286
    • Callsen, D.1    Brüne, B.2
  • 6
    • 0035725998 scopus 로고    scopus 로고
    • Cytochrome P450 epoxygenase metabolism of arachidonic acid inhibits apoptosis
    • Chen JK, Capdevila J, Harris RC (2001). Cytochrome P450 epoxygenase metabolism of arachidonic acid inhibits apoptosis. Mol Cell Biol 21: 6322 6331.
    • (2001) Mol Cell Biol , vol.21 , pp. 6322-6331
    • Chen, J.K.1    Capdevila, J.2    Harris, R.C.3
  • 7
    • 33749589959 scopus 로고    scopus 로고
    • Cytotoxicity of nitric oxide is alleviated by zinc-mediated expression of antioxidant genes
    • Chung MJ, Hogstrand C, Lee SJ (2006). Cytotoxicity of nitric oxide is alleviated by zinc-mediated expression of antioxidant genes. Exp Biol Med 231: 1555 1563.
    • (2006) Exp Biol Med , vol.231 , pp. 1555-1563
    • Chung, M.J.1    Hogstrand, C.2    Lee, S.J.3
  • 8
    • 0032740614 scopus 로고    scopus 로고
    • Extracellular signal-related kinase (ERK) and p38 mitogen-activated protein (MAP) kinases differentially regulate the lipopolysaccharide-mediated induction of inducible nitric oxide synthase and IL-12 in macrophages: Leishmania phosphoglycans subvert macrophage IL-12 production by targeting ERK MAP kinase
    • Feng GJ, Goodridge HS, Harnett MM, Wei XQ, Nikolaev AV, Higson AP et al. (1999). Extracellular signal-related kinase (ERK) and p38 mitogen-activated protein (MAP) kinases differentially regulate the lipopolysaccharide-mediated induction of inducible nitric oxide synthase and IL-12 in macrophages: Leishmania phosphoglycans subvert macrophage IL-12 production by targeting ERK MAP kinase. J Immunol 163: 6403 6412.
    • (1999) J Immunol , vol.163 , pp. 6403-6412
    • Feng, G.J.1    Goodridge, H.S.2    Harnett, M.M.3    Wei, X.Q.4    Nikolaev, A.V.5    Higson, A.P.6
  • 9
    • 0035955607 scopus 로고    scopus 로고
    • Cytochrome P450 enzymes in vascular homeostasis
    • Fleming I (2001). Cytochrome P450 enzymes in vascular homeostasis. Circ Res 89: 753 762.
    • (2001) Circ Res , vol.89 , pp. 753-762
    • Fleming, I.1
  • 11
    • 0022640297 scopus 로고
    • Superoxide anion is involved in the breakdown of endothelium-derived vascular relaxing factor
    • Gryglewski RJ, Palmer RMJ, Moncada S (1986). Superoxide anion is involved in the breakdown of endothelium-derived vascular relaxing factor. Nature 320: 454 456.
    • (1986) Nature , vol.320 , pp. 454-456
    • Gryglewski, R.J.1    Palmer, R.M.J.2    Moncada, S.3
  • 12
    • 0036138172 scopus 로고    scopus 로고
    • Involvement of CYP2J2 and CYP4F12 in the metabolism of ebastine in human intestinal microsomes
    • Hashizume T, Imaoka S, Mise M, Terauchi Y, Fujii T, Miyazaki H et al. (2002). Involvement of CYP2J2 and CYP4F12 in the metabolism of ebastine in human intestinal microsomes. J Pharmacol Exp Ther 300: 298 304.
    • (2002) J Pharmacol Exp Ther , vol.300 , pp. 298-304
    • Hashizume, T.1    Imaoka, S.2    Mise, M.3    Terauchi, Y.4    Fujii, T.5    Miyazaki, H.6
  • 13
    • 23444437459 scopus 로고    scopus 로고
    • Accumulation of 8-nitroguanine in the liver of patients with chronic hepatitis C
    • Horiike S, Kawanishi S, Kaito M, Ma N, Tanaka H, Fujita N et al. (2005). Accumulation of 8-nitroguanine in the liver of patients with chronic hepatitis C. J Hepatol 43: 403 410.
    • (2005) J Hepatol , vol.43 , pp. 403-410
    • Horiike, S.1    Kawanishi, S.2    Kaito, M.3    Ma, N.4    Tanaka, H.5    Fujita, N.6
  • 14
    • 21144459060 scopus 로고    scopus 로고
    • Cytochrome P450 2J2 promotes the neoplastic phenotype of carcinoma cells and is up-regulated in human tumors
    • Jiang JG, Chen CL, Card JW, Yang S, Chen JX, Fu XN et al. (2005). Cytochrome P450 2J2 promotes the neoplastic phenotype of carcinoma cells and is up-regulated in human tumors. Cancer Res 65: 4707 4715.
    • (2005) Cancer Res , vol.65 , pp. 4707-4715
    • Jiang, J.G.1    Chen, C.L.2    Card, J.W.3    Yang, S.4    Chen, J.X.5    Fu, X.N.6
  • 15
    • 0033559903 scopus 로고    scopus 로고
    • Overexpression of protein kinase C isoforms protects RAW264.7 macrophages from nitric oxide-induced apoptosis: Involvement of c-Jun N-terminal kinase/stress-activated protein kinase, p38 kinase and CPP32 protease pathways
    • Jun CD, Oh CD, Kwak HJ, Pae HO, Yoo JC, Choi BM et al. (1999a). Overexpression of protein kinase C isoforms protects RAW264.7 macrophages from nitric oxide-induced apoptosis: involvement of c-Jun N-terminal kinase/stress-activated protein kinase, p38 kinase and CPP32 protease pathways. J Immunol 162: 3395 3401.
    • (1999) J Immunol , vol.162 , pp. 3395-3401
    • Jun, C.D.1    Oh, C.D.2    Kwak, H.J.3    Pae, H.O.4    Yoo, J.C.5    Choi, B.M.6
  • 16
    • 0033602849 scopus 로고    scopus 로고
    • Modulation of nitric oxide-induced apoptotic death of HL-60 cells by protein kinase C and protein kinase A through mitogen-activated protein kinases and CPP32-like protease pathways
    • Jun CD, Pae HO, Kwak HJ, Yoo JC, Choi BM, Oh CD et al. (1999b). Modulation of nitric oxide-induced apoptotic death of HL-60 cells by protein kinase C and protein kinase A through mitogen-activated protein kinases and CPP32-like protease pathways. Cell Immunol 194: 36 46.
    • (1999) Cell Immunol , vol.194 , pp. 36-46
    • Jun, C.D.1    Pae, H.O.2    Kwak, H.J.3    Yoo, J.C.4    Choi, B.M.5    Oh, C.D.6
  • 17
    • 28644431994 scopus 로고    scopus 로고
    • Trans-arachidonic acids generated during nitrative stress induce a thrombospondin-1-dependent microvascular degeneration
    • Kermorvant-Duchemin E, Sennlaub F, Sirinyan M, Brault S, Andelfinger G, Kooli A et al. (2005). Trans-arachidonic acids generated during nitrative stress induce a thrombospondin-1-dependent microvascular degeneration. Nature Med 11: 1339 1345.
    • (2005) Nature Med , vol.11 , pp. 1339-1345
    • Kermorvant-Duchemin, E.1    Sennlaub, F.2    Sirinyan, M.3    Brault, S.4    Andelfinger, G.5    Kooli, A.6
  • 18
    • 0030829981 scopus 로고    scopus 로고
    • Nitric oxide modulates the c-Jun N-terminal kinase/stress-activated protein kinase activity through activating c-Jun N-terminal kinase kinase
    • Kim H, Shim J, Han PL, Choi EJ (1997). Nitric oxide modulates the c-Jun N-terminal kinase/stress-activated protein kinase activity through activating c-Jun N-terminal kinase kinase. Biochemistry 36: 13677 13681.
    • (1997) Biochemistry , vol.36 , pp. 13677-13681
    • Kim, H.1    Shim, J.2    Han, P.L.3    Choi, E.J.4
  • 19
    • 0037059796 scopus 로고    scopus 로고
    • ERK1/2 and p38 kinase oppositely regulate nitric oxide-induced apoptosis of chondrocytes in association with p53, caspase-3 and differentiation status
    • Kim SJ, Ju JW, Oh CD, Yoon YM, Song WK, Lim JH et al. (2002). ERK1/2 and p38 kinase oppositely regulate nitric oxide-induced apoptosis of chondrocytes in association with p53, caspase-3 and differentiation status. J Biol Chem 277: 1332 1339.
    • (2002) J Biol Chem , vol.277 , pp. 1332-1339
    • Kim, S.J.1    Ju, J.W.2    Oh, C.D.3    Yoon, Y.M.4    Song, W.K.5    Lim, J.H.6
  • 20
    • 0034678608 scopus 로고    scopus 로고
    • Cyclic GMP-dependent and -independent regulation of MAP kinases by sodium nitroprusside in isolated cardiomyocytes
    • Kim SO, Xu YJ, Katz S, Pelech S (2000). Cyclic GMP-dependent and -independent regulation of MAP kinases by sodium nitroprusside in isolated cardiomyocytes. Biochim Biophys Acta 1498: 277 284.
    • (2000) Biochim Biophys Acta , vol.1498 , pp. 277-284
    • Kim, S.O.1    Xu, Y.J.2    Katz, S.3    Pelech, S.4
  • 21
    • 1842332149 scopus 로고    scopus 로고
    • Cyclooxygenase-2: An essential regulator of NO-mediated apoptosis
    • von Knethen A, Brune B (1997). Cyclooxygenase-2: an essential regulator of NO-mediated apoptosis. FASEB J 11: 887 895.
    • (1997) FASEB J , vol.11 , pp. 887-895
    • Von Knethen, A.1    Brune, B.2
  • 23
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
    • Livak KJ, Schmittgen TD (2001). Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25: 402 408.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 24
    • 27744450038 scopus 로고    scopus 로고
    • Characterisation of a c-Jun - Responsive module in the 5′flank of the human CYP2J2 gene that regulates transactivation
    • Marden NY, Murray M (2005). Characterisation of a c-Jun - responsive module in the 5′flank of the human CYP2J2 gene that regulates transactivation. Biochem J 391: 631 640.
    • (2005) Biochem J , vol.391 , pp. 631-640
    • Marden, N.Y.1    Murray, M.2
  • 25
    • 0043069910 scopus 로고    scopus 로고
    • Role of activator protein-1 in the down-regulation of the human CYP2J2 gene in hypoxia
    • Marden NY, Fiala-Beer E, Xiang SH, Murray M (2003). Role of activator protein-1 in the down-regulation of the human CYP2J2 gene in hypoxia. Biochem J 373: 669 680.
    • (2003) Biochem J , vol.373 , pp. 669-680
    • Marden, N.Y.1    Fiala-Beer, E.2    Xiang, S.H.3    Murray, M.4
  • 26
    • 0022471136 scopus 로고
    • Drug Metabolism in cirrhosis: Selective changes in cytochrome P-450 isozymes in the choline-deficient rat model
    • Murray M, Zaluzny L, Farrell GC (1986). Drug Metabolism in cirrhosis: selective changes in cytochrome P-450 isozymes in the choline-deficient rat model. Biochem Pharmacol 35: 1817 1824.
    • (1986) Biochem Pharmacol , vol.35 , pp. 1817-1824
    • Murray, M.1    Zaluzny, L.2    Farrell, G.C.3
  • 27
    • 0033588034 scopus 로고    scopus 로고
    • Anti-inflammatory properties of cytochrome P450 epoxygenase-derived eicosanoids
    • Node K, Huo Y, Ruan X, Yang B, Spieker M, Ley K et al. (1999). Anti-inflammatory properties of cytochrome P450 epoxygenase-derived eicosanoids. Science 285: 1276 1279.
    • (1999) Science , vol.285 , pp. 1276-1279
    • Node, K.1    Huo, Y.2    Ruan, X.3    Yang, B.4    Spieker, M.5    Ley, K.6
  • 28
    • 0030605013 scopus 로고    scopus 로고
    • Nitric oxide stimulates stress-activated protein kinases in glomerular endothelial and mesangial cells
    • Pfeilschifter J, Huwiler A (1996). Nitric oxide stimulates stress-activated protein kinases in glomerular endothelial and mesangial cells. FEBS Lett 396: 67 70.
    • (1996) FEBS Lett , vol.396 , pp. 67-70
    • Pfeilschifter, J.1    Huwiler, A.2
  • 29
    • 0029005508 scopus 로고
    • Nitric oxide and cGMP analogs activate transcription from AP-1-responsive promoters in mammalian cells
    • Pilz RB, Suhasini M, Idriss S, Meinkoth JL, Boss GR (1995). Nitric oxide and cGMP analogs activate transcription from AP-1-responsive promoters in mammalian cells. FASEB J 9: 552 558.
    • (1995) FASEB J , vol.9 , pp. 552-558
    • Pilz, R.B.1    Suhasini, M.2    Idriss, S.3    Meinkoth, J.L.4    Boss, G.R.5
  • 30
    • 0042564502 scopus 로고    scopus 로고
    • Nitric oxide is involved in establishing the balance between cell cycle progression and cell death in the developing neural tube
    • Plachta N, Traister A, Weil M (2003). Nitric oxide is involved in establishing the balance between cell cycle progression and cell death in the developing neural tube. Exp Cell Res 288: 354 362.
    • (2003) Exp Cell Res , vol.288 , pp. 354-362
    • Plachta, N.1    Traister, A.2    Weil, M.3
  • 32
    • 0036080081 scopus 로고    scopus 로고
    • P450 metabolites of arachidonic acid in the control of cardiovascular function
    • Roman RJ (2002). P450 metabolites of arachidonic acid in the control of cardiovascular function. Physiol Rev 82: 131 185.
    • (2002) Physiol Rev , vol.82 , pp. 131-185
    • Roman, R.J.1
  • 33
    • 0035512186 scopus 로고    scopus 로고
    • Transcription activator protein 1 (AP-1) mediates NO-induced apoptosis of adult cardiomyocytes
    • Taimor G, Rakow A, Piper HM (2001). Transcription activator protein 1 (AP-1) mediates NO-induced apoptosis of adult cardiomyocytes. FASEB J 15: 2518 2520.
    • (2001) FASEB J , vol.15 , pp. 2518-2520
    • Taimor, G.1    Rakow, A.2    Piper, H.M.3
  • 34
    • 0029935418 scopus 로고    scopus 로고
    • Regulation of transcription by MAP kinase cascades
    • Treisman R (1996). Regulation of transcription by MAP kinase cascades. Curr Opin Cell Biol 8: 205 215.
    • (1996) Curr Opin Cell Biol , vol.8 , pp. 205-215
    • Treisman, R.1
  • 35
    • 0027333030 scopus 로고
    • 14,15-Epoxyeicosatrienoic acid metabolism in endothelial cells
    • VanRollins M, Kaduce TL, Knapp HR, Spector AA (1993). 14,15-Epoxyeicosatrienoic acid metabolism in endothelial cells. J Lipid Res 34: 1931 1942.
    • (1993) J Lipid Res , vol.34 , pp. 1931-1942
    • Vanrollins, M.1    Kaduce, T.L.2    Knapp, H.R.3    Spector, A.A.4
  • 36
    • 0029841018 scopus 로고    scopus 로고
    • Measurement of nitric oxide and peroxynitrite generation in the postischemic heart
    • Wang P, Zweier JL (1996). Measurement of nitric oxide and peroxynitrite generation in the postischemic heart. J Biol Chem 271: 29223 29230.
    • (1996) J Biol Chem , vol.271 , pp. 29223-29230
    • Wang, P.1    Zweier, J.L.2
  • 37
    • 0030063499 scopus 로고    scopus 로고
    • Molecular cloning and expression of CYP2J2, a human cytochrome P450 arachidonic acid epoxygenase highly expressed in heart
    • Wu S, Moomaw CR, Tomer KB, Falck JR, Zeldin DC (1996). Molecular cloning and expression of CYP2J2, a human cytochrome P450 arachidonic acid epoxygenase highly expressed in heart. J Biol Chem 271: 3460 3468.
    • (1996) J Biol Chem , vol.271 , pp. 3460-3468
    • Wu, S.1    Moomaw, C.R.2    Tomer, K.B.3    Falck, J.R.4    Zeldin, D.C.5
  • 38
    • 33845712373 scopus 로고    scopus 로고
    • Inter-individual variation of cytochrome P4502J2 expression and catalytic activities in liver microsomes from Japanese and Caucasian populations
    • Yamazaki H, Okayama A, Imai N, Guengerich FP, Shimizu M (2006). Inter-individual variation of cytochrome P4502J2 expression and catalytic activities in liver microsomes from Japanese and Caucasian populations. Xenobiotica 36: 1201 1209.
    • (2006) Xenobiotica , vol.36 , pp. 1201-1209
    • Yamazaki, H.1    Okayama, A.2    Imai, N.3    Guengerich, F.P.4    Shimizu, M.5
  • 39
    • 0034923447 scopus 로고    scopus 로고
    • Overexpression of cytochrome P450 CYP2J2 protects against hypoxia-reoxygenation injury in cultured bovine aortic endothelial cells
    • Yang B, Graham L, Dikalov S, Mason RP, Falck JP, Liao JK et al. (2001). Overexpression of cytochrome P450 CYP2J2 protects against hypoxia-reoxygenation injury in cultured bovine aortic endothelial cells. Mol Pharmacol 60: 310 320.
    • (2001) Mol Pharmacol , vol.60 , pp. 310-320
    • Yang, B.1    Graham, L.2    Dikalov, S.3    Mason, R.P.4    Falck, J.P.5    Liao, J.K.6
  • 40
    • 0029889723 scopus 로고    scopus 로고
    • Biochemical characterization of the human liver Cytochrome P450 arachidonic acid epoxygenase pathway
    • Zeldin DC, Moomaw CR, Jesse N, Tomer KB, Beetham J, Hammock BD et al. (1996). Biochemical characterization of the human liver Cytochrome P450 arachidonic acid epoxygenase pathway. Arch Biochem Biophys 330: 87 96.
    • (1996) Arch Biochem Biophys , vol.330 , pp. 87-96
    • Zeldin, D.C.1    Moomaw, C.R.2    Jesse, N.3    Tomer, K.B.4    Beetham, J.5    Hammock, B.D.6
  • 41
    • 0031057495 scopus 로고    scopus 로고
    • Predominant expression of an arachidonate epoxygenase in islets of Langerhans cells in human and rat pancreas
    • Zeldin DC, Foley J, Boyle JE, Moomaw CR, Tomer KB, Parker C et al. (1997a) Predominant expression of an arachidonate epoxygenase in islets of Langerhans cells in human and rat pancreas. Endocrinology 138: 1338 1346.
    • (1997) Endocrinology , vol.138 , pp. 1338-1346
    • Zeldin, D.C.1    Foley, J.2    Boyle, J.E.3    Moomaw, C.R.4    Tomer, K.B.5    Parker, C.6
  • 42
    • 0030960145 scopus 로고    scopus 로고
    • CYP2J subfamily cytochrome P450s in the gastrointestinal tract: Expression, localization, and potential functional significance
    • Zeldin DC, Foley J, Goldsworthy SM, Cook ME, Boyle JE, Ma J et al. (1997b) CYP2J subfamily cytochrome P450s in the gastrointestinal tract: expression, localization, and potential functional significance. Mol Pharmacol 51: 931 943.
    • (1997) Mol Pharmacol , vol.51 , pp. 931-943
    • Zeldin, D.C.1    Foley, J.2    Goldsworthy, S.M.3    Cook, M.E.4    Boyle, J.E.5    Ma, J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.